Heterobifunctional cross-linkers containing 4,9-dioxa-1,12-dodecanediamine spacers

Bioconjugate Chemistry

Volumn 8, Issue 3, 1997, Pages 447-452

  Johnson, Gary M ^a   Albarella, James P ^a   Petry, Christoph ^b  

^a Organic Chemistry Group   (India)

^b BAYER AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACID CHLORIDES; CROSSLINKER; HETEROBIFUNCTIONAL LINKER;

CHLORINE COMPOUNDS;

EID: 0031149732     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc970026o     Document Type: Article

References (7)

1. (a) Nagasawa, T., et al. (1973) New Agents for t-Butyloxy-carbonylation and Methoxybenzyloxycarbonylation of Amino Acids. Bull. Chem. Soc. Jpn. 46, 1269-1272.
2. (b) Sheldon, E. L., Levenson, C. H., Mullis, K. B., and Rapoport, H. (1989) N-Substituted 4,9-Dioxa-1,2-dodecane Diamines Useful for Preparing Nucleic Acid Intercalators. EP 0 309 006 Al.
3. (c) Baer, B. W., Groves, E. S., Houston, L. L., and Levenson, C. H. (1989) Conjugates of Antisense Oligonucleotides & Therapeutic Uses Thereof. WO 91/04753.
4. (d) Houston, L. L., Aldwin, L., and Nitecki, D. E. (1991) Thioether Linked Immunotoxin Conjugates. U.S. 5,024,834.
5. (a) Henry, D. W. (1966) Heterocycl. Chem., 503-511.
6. (b) Voerman, M. G. L. (1904) Acc. Trav. Pays Bas, 265-282.
7. Greene, T. W. (1981) Protecting Groups in Organic Synthesis: tBOC Deprotection, John Wiley & Sons, New York.