Biochemical, biophysical, and pharmacological characterization of bacterially expressed human agouti-related protein

Biochemistry

Volumn 37, Issue 46, 1998, Pages 16041-16052

  Rosenfeld, Robert D ^a   Zeni, Lisa ^a   Welcher, Andrew A ^a   Narhi, Linda O ^a   Hale, Clarence ^a   Marasco, Julie ^a   Delaney, John ^a   Gleason, Thomas ^a   Philo, John S ^a   Katta, Viswanathan ^a   Hui, John ^a   Baumgartner, Jamie ^a   Graham, Melissa ^a   Stark, Kevin L ^a   Karbon, William ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; DISULFIDE; GENE PRODUCT; LEPTIN; MELANOCORTIN RECEPTOR; PROTEIN;

ANIMAL CELL; ARTICLE; CIRCULAR DICHROISM; DIABETES MELLITUS; ESCHERICHIA COLI; FEEDING BEHAVIOR; GENE; GENE EXPRESSION; HYPOTHALAMUS; IMMUNOBLOTTING; MASS SPECTROMETRY; MOUSE; NONHUMAN; OBESITY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEDIMENTATION RATE;

AMINO ACID SEQUENCE; CELL LINE; CHEMISTRY, PHYSICAL; CIRCULAR DICHROISM; ESCHERICHIA COLI; GENETIC VECTORS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY; LYSINE; METHIONINE; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PITUITARY GLAND, ANTERIOR; PROTEIN BINDING; PROTEIN FOLDING; PROTEINS; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SULFHYDRYL COMPOUNDS; TRANSFECTION;

EID: 0032542061     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi981027m     Document Type: Article

References (36)

1. Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., and Friedman, J. M. (1994) Nature 372, 425.
2. Naggert, J. K., Frisker, L. D., Varlamov, O., et al. (1995) Nat. Genet. 10, 135-142.
3. Noben-Trauth, K., Naggert, J. K., North, M. A., and Nishina, P. M. (1996) Nature 380, 534-538.
4. Kleyn, P. W., Fan, W., Kovats, S. G., et al. (1996) Cell 85, 281-290.
5. Cuenot, L. (1905) Arch. Zool. Exp. Gen. 3, 123-132.
6. Manne, J., Argeson, A. C., and Siracusa, L. D. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 4721-4724.
7. Bultman, S. J., Michaud, E. J., and Woychik, R. P. (1992) Cell 71, 1195-1204.
8. Lu, D., Willard, D., Patel, I. R., Kadwell, S., Overton, L., Kost, T., Luther, M., Chen, W., Woychik, R. P., Wilkinson, W. O., and Cone, R. D. (1994) Nature 371, 799-802.
9. Fan, W., Boston, B. A., Kesterson, R. A., Hruby, V. J., and Cone, R. D. (1997) Nature 385, 165-168.
10. Huszar, D., Lynch, C. A., Fairchild-Huntress, V., Dunmore, J. H., Fand, Q., Berkmeier, L. R., Boston, B. A., Cone, R., Smith, F. J., Campfield, L. A., Burn, P., and Lee, F. (1997) Cell 88, 131-141.
11. Shutter, J. R., Graham, M., Kinsey, A. C., Scully, S., Lüthy, R., and Stark, K. L. (1997) Genes Dev. 11, 593-602.
12. Graham, M., Shutter, J. R., Sarmiento, U., Sarosi, I., and Stark, K. L. (1997) Nat. Genet. 17, 274.
13. Ollmann, M. M., Wilson, B. D., Yang, Y.-K., Kerns, J. A., Chen, Y., Gantz, I., and Barsh, G. S. (1997) Science 278, 135-138.
14. Fong, T. M., Mao, C., MacNeil, T., et al. (1997) Biochem. Biophys. Res. Commun. 237, 629-631.
15. Laemmli, U. K. (1970) Nature 227, 680-685.
16. Towbin, H., Staehelin, T., and Gordon, J. (1979) Proc. Natl. Acad. Sci. U.S.A. 76, 4350-4354.
17. Philo, J. S. (1997) Biophys. J. 72, 435.
18. Laue, T. M., Shah, B. D., Ridgeway, T. M., and Pelletier, S. L. (1992) in Analytical ultracentrifugation in biochemistry and polymer science (Harding, S. E., Rowe, A. J., and Horton, J. C., Eds.) pp 90-125, Royal Society of Chemistry, Cambridge, U.K.
19. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254.
20. Ellman, G. L. (1959) Arch. Biochem. Biophys. 82, 70-77.
21. Arunlakshan, O., and Schild, H. O. (1959) Br. J. Pharmacol. 14, 48-58.
22. Stempfer, G., Neugebauer, B. H., and Rudolph, R. (1995) Nat. Biotechnol. 14, 329-334.
23. Shoemaker, J. M., Brasnett, A. H., and Marston, F. A. O. (1985) EMBO J. 4, 775-780.
24. Hober, S., Forsberg, G., Palm, G., Hartmanus, M., and Nilsson, B. (1992) Biochemistry 31, 1749-1756.
25. Langley, K. E., Lai, P. H., Wypych, J., Everett, R. R., Berg, T. F., Krabill, L. F., and Souza, L. M. (1987) Eur. J. Biochem. 163, 323-330.
26. Chang, C. T., Wu, C.-S. C., and Yang, J. T. (1978) Anal. Biochem. 91, 13-31.
27. Willard, D. H., Bodnar, W., Harris, C., Kiefer, L., Nichols, J. S., Blanchard, S., Hoffman, C., Moyer, M., Burkhart, W., Weiel, J., Luther, M. A., Wilkison, W. O., and Roque, W. J. (1995) Biochemistry 34, 12341-12346.
28. Narhi, L. O., Philo, J. S., Li, T., Zhang, M., Samal, B., and Arakawa, T. (1996) Biochemistry 35, 11454-11460.
29. Gast, K., Damaschun, H., Eckert, K., Schulze-Forster, K., Maurer, H. R., Muler-Frohne, D. Z., Czarnecki, J., and Damaschun, G. (1995) Biochemistry 34, 13211-13218.
30. Fink, A. L., Calciano, L. J., Goto, Y., Karotsu, T., and Pallaro, D. R. (1994) Biochemistry 33, 12504-12511.
31. Eipper, B. A., and Mains, R. E. (1976) Endocr. Rev. 1, 1-27.
32. Moore, H. P. H., Walker, M. D., Lee, F., and Kelly, R. B. (1983) Cell 35, 531-538.
33. Nagahama, M., Nakayama, K., and Murakami, K. (1991) Eur. J. Biochem. 197, 135-140.
34. Dickerson, I. M., Dixon, J. E., and Mains, R. E. (1987) J. Biol. Chem. 262, 13646-13653.
35. Klebig, M. L., Wilkinson, J. E., Geisler, J. G., and Woychik, R. P. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 4728-4732.
36. Bures, E. J., Hui, J. O., Young, Y., Chow, D. T., Katta, V., Rhode, M. F., Zeni, L., Rosenfeld, R. D., Stark, K. L., and Haniu, M. (1998) Biochemistry (in press).