Systemic administration of a nerve growth factor conjugate reverses age- related cognitive dysfunction and prevents cholinergic neuron atrophy

Journal of Neuroscience

Volumn 16, Issue 17, 1996, Pages 5437-5442

  Bäckman, Cristina ^a   Rose, Gregory M ^a,b   Hoffer, Barry J ^a   Henry, Michael A ^a   Bartus, Raymond T ^c   Friden, Phillip ^c,e   Granholm, Ann Charlotte ^a,d  

^a UNIVERSITY OF COLORADO   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c ALKERMES INC   (United States)

^d UNIVERSITY OF COLORADO   (United States)

^e Periodontix Inc   (United States)

Author keywords

acetylcholine; Alzheimer's disease; basal forebrain; nerve growth factor; neurotrophic factors; plasticity; regeneration; septal nucleus

Indexed keywords

NERVE GROWTH FACTOR;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; CHOLINERGIC NERVE CELL; COGNITIVE DEFECT; CONTROLLED STUDY; COVALENT BOND; ENDOTHELIUM CELL; FOREBRAIN; IMMUNOREACTIVITY; INTRAVENOUS DRUG ADMINISTRATION; NERVE CELL PLASTICITY; NERVE REGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; SPATIAL MEMORY;

EID: 0029843679     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-17-05437.1996     Document Type: Article

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