Impaired modulation of sympathetic excitability by nitric oxide after long-term administration of organic nitrates in pigs

Circulation

Volumn 97, Issue 23, 1998, Pages 2352-2358

  Zanzinger, Johannes ^a   Czachurski, Jürgen ^b   Seller, Horst ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b NONE

Author keywords

Brain; Nervous system; Nitric oxide

Indexed keywords

NITRIC OXIDE;

ANIMAL EXPERIMENT; ARTICLE; ELECTROSTIMULATION THERAPY; HEART OUTPUT; HEMODYNAMICS; MEAN ARTERIAL PRESSURE; NERVE CELL EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; SWINE; SYMPATHETIC TONE;

EID: 0032537518     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.97.23.2352     Document Type: Article

References (38)

1. Moncada S, Higgs A. Mechanisms of disease: the L-arginine-nitric oxide pathway. N Engl J Med. 1993;329:2002-2012.
2. Fleming I, Bauersachs J, Busse R. Paracrine functions of the coronary vascular endothelium. Mol Cell Biochem. 1996;157:137-145.
3. Zanzinger J, Czachurski J, Seller H. Inhibition of sympathetic vasoconstriction is a major principle of vasodilation by nitric oxide in vivo. Circ Res. 1994;75:1073-1077.
4. Hirai T, Musch TI, Morgan DA, Kregel KC, Claassen DE, Pickar JG, Lewis SJ, Kenney MJ. Differential sympathetic nerve responses to nitric oxide synthase inhibition in anesthetized rats. Am J Physiol. 1995;269:R807-R813.
5. Harada S, Tokunaga S, Momohara M, Masaki H, Tagawa T, Imaizumi T, Takeshita A. Inhibition of nitric oxide formation in the nucleus tractus solitarius increases renal sympathetic nerve activity in rabbits. Circ Res. 1993;72:511-516.
6. Matsuoka H, Nishida H, Nomura G, Van Vliet BN, Toshima H. Hypertension induced by nitric oxide synthesis inhibition is renal nerve dependent. Hypertension. 1994;23:971-975.
7. Anderson TJ, Meredith IT, Ganz P, Selwyn AP, Yeung AC. Nitric oxide and nitrovasodilators: similarities, differences and potential interactions. J Am Coll Cardiol. 1994;24:555-566.
8. Harrison DG, Bates JN. The nitrovasodilators: new ideas about old drugs. Circulation. 1993;87:1461-1467.
9. Bassenge E, Zanzinger J. Nitrates in different vascular beds, nitrate tolerance, and interactions with endothelial function. Am J Cardiol. 1992;70:23B-29B.
10. Laursen JB, Mulsch A, Boesgaard S, Mordvintcev P, Trautner S, Gruhn N, Nielsenkudsk JE, Busse R, Aldershvile J. In vivo nitrate tolerance is not associated with reduced bioconversion of nitroglycerin to nitric oxide. Circulation. 1996;94:2241-2247.
11. Münzel T, Sayegh H, Freeman BA, Tarpey M, Harrison DG. Evidence for enhanced vascular superoxide anion production in nitrate tolerance. J Clin Invest. 1995;95:187-194.
12. Münzel T, Giaid A, Kurz S, Stewart DJ, Harrison DG. Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance. Proc Natl Acad Sci U S A. 1995;92:5244-5248.
13. Parker JD, Farrell B, Fenton T, Cohanim M, Parker JO. Counterregulatory responses to continuous and intermittent therapy with nitroglycerin. Circulation. 1991;84:2336-2345.
14. Schwarz P, Diem R, Dun NJ, Förstermann U. Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart sympathetic nerves. Circ Res. 1995;77:841-848.
15. Zanzinger J, Czachurski J, Seller H. Neuronal nitric oxide reduces sympathetic excitability by modulation of central glutamate effects in pigs. Circ Res. 1997;80:565-571.
16. Berman AL. The Brain Stem of the Cat. Madison/Milwaukee, Wis: The University of Wisconsin Press; 1968.
17. Zanzinger J, Seller H. Species differences in the distribution of nitric oxide synthase in brain stem regions that regulate sympathetic activity. Brain Res. 1997;764:265-268.
18. Dampney RAL. Functional organization of central pathways regulating the cardiovascular system. Physiol Rev. 1994;74:323-364.
19. Dupuis J, Lalonde G, Lemieux R, Rouleau J. Tolerance by intravenous nitroglycerin in patients with congestive heart failure: role of increased intravascular volume, neurohumoral activation and lack of prevention with N-acetylcysteine. J Am Coll Cardiol. 1990;16:923-931.
20. Parker JO. Nitrate tolerance-problems both new and old. Can J Cardiol. 1996;12(suppl C):5C-8C.
21. Kirchheim HR, Finke R, Hackenthal E, Löwe W, Persson P. Baroreflex sympathetic activation increases threshold pressure for the pressure-dependent renin release in conscious dogs. Pflugers Arch. 1985;405:127-135.
22. Münzel T, Bassenge E. Long-term angiotensin-converting enzyme inhibition with high dose enalapril retards nitrate tolerance in large epicardial arteries and prevents rebound coronary vasoconstriction in vivo. Circulation. 1996;93:2052-2058.
23. Münzel T, Heitzer T, Kurz S, Harrison DG, Luhman C, Pape L, Olschewski M, Just H. Dissociation of coronary vascular tolerance and neurohumoral adjustments during long-term nitroglycerin therapy in patients with stable coronary artery disease. J Am Coll Cardiol. 1996;27:297-303.
24. Parker JD, Parker JO. Effect of therapy with an angiotensin-converting enzyme inhibitor on hemodynamic and counterregulatory responses during continuous therapy with nitroglycerin. J Am Coll Cardiol. 1993;21:1445-1453.
25. Stewart DJ, Elsner D, Sommer O, Holtz J, Bassenge E. Altered spectrum of nitroglycerin action in long-term treatment: nitroglycerin-specific venous tolerance with maintenance of arterial vasodepressor potency. Circulation. 1986;74:573-582.
26. Zanzinger J, Czachurski J, Seller H. Effects of nitric oxide on sympathetic baroreflex transmission in the nucleus tractus solitarii and caudal ventrolateral medulla in cats. Neurosci Lett. 1995;197:199-202.
27. Zanzinger J, Czachurski J, Seller H. Lack of nitric oxide sensitivity of carotid sinus baroreceptors activated by normal blood pressure stimuli in cats. Neurosci Lett. 1996;208:121-124.
28. Jimbo M, Suzuki H, Ichikawa M, Kumagai K, Nishizawa M, Saruta T. Role of nitric oxide in regulation of baroreceptor reflex. J Auton Nerv Syst. 1994;50:209-219.
29. Liu JL, Murakami H, Zucker IH. Effects of NO on baroreflex control of heart rate and renal nerve activity in conscious rabbits. Am J Physiol. 1996;39:R1361-R1370.
30. Griscavage JM, Fukuto JM, Komori Y, Ignarro LJ. Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group: role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide. J Biol Chem. 1994;269:21644-21649.
31. Hökfelt T, Ceccatelli S, Gustafsson L, Hulting A-L, Verge V, Villar M, Xu X-J, Xu Z-Q. Wiesenfeld-Hallin Z, Zhang X. Plasticity of NO synthase expression in the nervous and endocrine systems. Neuropharmacology, 1994;33:1221-1227.
32. Scharfstein JS, Keaney JF Jr, Slivka A, Welch GN, Vita JA, Stamler JS, Loscalzo J. In vivo transfer of nitric oxide between a plasma protein-bound reservoir and low molecular weight thiols. J Clin Invest. 1994;94:1432-1439.
33. Jia L, Bonaventura C, Bonaventura J, Stamler JS. S-Nitrosohemoglobin: a dynamic activity of blood involved in vascular control. Nature. 1996;380:221-226.
34. Abrams J. Interval therapy to avoid nitrate tolerance: paradise regained. Am J Cardiol. 1989;64:931-934.
35. Parker JO, Amies MH, Hawkinson RW, Heilman JM, Hougham AJ, Vollmer MC, Wilson RR. Intermittent transdermal nitroglycerin therapy in angina pectoris: clinically effective without tolerance or rebound: Minitran Efficacy Study Group. Circulation. 1995;91:1368-1374.
36. Zanzinger J, Feelisch M, Bassenge E. Novel organic nitrates are potent dilators of large coronary arteries with reduced development of tolerance during long-term infusion in dogs: role of the sulfhydryl moiety. J Cardiovasc Pharmacol. 1994;23:772-778.
37. Arnal JF, Rami J, Souchard JP, Tack I, Besombes JP. Role of the superoxide anion on biological activity of nitric oxide produced by the endothelium. Arch Physiol Biochem. 1996;104:D27-D28.
38. Bassenge E, Fink B. Tolerance to nitrates and simultaneous upregulation of platelet activity prevented by enhancing antioxidant state. Naunyn Schmiedebergs Arch Pharmacol. 1996;353:363-367.