Effects of NO on baroreflex control of heart rate and renal nerve activity in conscious rabbits

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 270, Issue 6 39-6, 1996, Pages

  Liu, Jun Li ^a   Murakami, Hiroshi ^a   Zucker, Irving H ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

autonomic tone; blood pressure; nitric oxide; vagus

Indexed keywords

ATROPINE; METOPROLOL; N(G) NITROARGININE; NITRIC OXIDE;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; AORTA NERVE; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; HEART RATE; KIDNEY NERVE; MALE; MEAN ARTERIAL PRESSURE; NERVE STIMULATION; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RABBIT; SYMPATHETIC TONE; VAGUS NERVE;

EID: 0029798158     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1996.270.6.r1361     Document Type: Article

References (34)

1. Bell, L. B., K. P. O'Hagen, and P. S. Clifford. Cardiac but not pulmonary receptors mediate depressor response to IV phenyl biguanide in conscious rabbits. Am. J. Physiol. 264 (Regulatory Integrative Comp. Physiol. 33): R1050-R1057, 1993.
2. Dorward, P. K., W. Riedel, S. L. Burke, J. Gipps, and P. I. Korner. The renal sympathetic baroreflex in the rabbits: arterial and cardiac baroreceptor influences, resetting, and effect of anesthesia. Circ. Res. 57: 618-633, 1985.
3. Du, Z.-Y., G. J. Dusting, and O. L. Woodman. Hemodynamic responses to N-nitro-L-arginine in conscious rabbits. Clin. Exp. Pharmacol. Physiol. 18: 371-374, 1991.
4. Du, Z.-Y., G. J. Dusting, and O. L. Woodman. Baroreceptor reflexes and vascular reactivity during inhibition of nitric oxide synthesis in conscious rabbits. Eur. J. Pharmacol. 214: 21-26, 1992.
5. Dubbin, P. N., M. Zambetis, and G. J. Dusting. Inhibition of endothelial nitric oxide biosynthesis by N-nitro-L-arginine. Clin. Exp. Pharmacol. Physiol. 17: 281-286, 1990.
6. Garthwaite, J., and C. L. Boulton. Nitric oxide signaling in the central nervous system. Annu. Rev. Physiol. 57: 683-706, 1995.
7. Garthwaite, J., S. L. Charles, and R. Chess-Williams. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature Lond. 336: 385-388, 1988.
8. Gebber, G. L., and D. W. Snyder. Hypothalamic control of baroreflex. Am. J. Physiol. 218: 124-131, 1969.
9. Hansen, J., T. N. Jacobsen, and R. G. Victor. Is nitric oxide involved in the tonic inhibition of central sympathetic outflow in humans? Hypertension Dallas 24: 439-444, 1994.
10. Harada, S., S. Tokunaga, M. Momohara, H. Masaki, T. Tagawa, T. Imaizumi, and A. Takeshita. Inhibition of nitric oxide formation in the nucleus tractus solitarius increases renal sympathetic nerve activity in rabbits. Circ. Res. 72: 511-516, 1993.
11. Hassall, C. J. S., M. J. Saffrey, A. Belai, C. H. V. Hoyle, E. W. Moules, J. Moss, H. H. H. W. Schmidt, F. Murad, U. Förstermann, and G. Burnstock. Nitric oxide synthase immunoreactivity and NADPH-diaphorase activity in a subpopulation of intrinsic neurones of the guinea-pig heart. Neurosci. Lett. 143: 65-68, 1992.
12. Höhler, B., B. Mayer, and W. Kummer. Nitric oxide synthase in the rat carotid body and carotid sinus. Cell Tissue Res. 276: 559-564, 1994.
13. Horn, T., P. M. Smith, B. E. McLaugblin, L. Bauce, G. S. Marks, Q. J. Pittman, and A. V. Ferguson. Nitric oxide actions in paraventricular nucleus: cardiovascular and neurochemical implications. Am. J. Physiol. 266 (Regulatory Integrafive Comp. Physiol. 35): R306-R313, 1994.
14. Iadecola, C., P. L. Faris, B. K. Hartman, and X. Xu. Localization of NADPH diaphorase in neurons of the rostral ventral medulla: possible role of nitric oxide in central autonomic regulation of oxygen chemoreception. Brain Res. 603: 173-179, 1993.
15. Jimbo, M., H. Suzuki, M. Ichikawa, K. Kumagai, M. Nishizawa, and T. Saruta. Role of nitric oxide in regulation of baroreceptor reflex. J. Auton. Nerv. Sys. 50: 209-219, 1994.
16. Kent, B. B., J. W. Drane, B. Blumenstein, and J. W. Manning. A mathematical model to assess changes in the baroreceptor reflex. Cardiology 57: 295-310, 1972.
17. Kumagai, H., D. B. Averill, M. C. Khosla, and C. M. Ferrario. Role of nitric oxide and angiotensin II in the regulation of sympathetic nerve activity in spontaneously hypertensive rats. Hypertension Dallas 21: 476-484, 1993.
18. Ma, S., A. Sandra, and F. Abboud. Expression of nitric oxide synthase gene in the brain stem is dependent on baroreceptor input (Abstract). FASEB J. 9: A44, 1995.
19. Ma, S., P. G. Schmid, Jr., and J. P. Long. Noradrenergic mechanisms and the cardiovascular actions of nitroglycerin. Life Sci. 55: 1595-1603, 1994.
20. Matsuda, T., J. N. Bates, S. J. Lewis, F. M. Abboud, and M. W. Chapleau. Modulation of baroreceptor activity by nitric oxide and S-nitrosocysteine. Circ. Res. 76: 426-433, 1995.
21. Matsukawa, S., and I. A. Reid. Role of the area postrema in the modulation of the baroreflex control of heart rate by angiotensin II. Circ. Res. 67: 1462-1473, 1990.
22. Palmer, R. M. J., D. S. Ashton, and S. Moncada. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature Lond. 333: 664-666, 1988.
23. Palmer, R. M. J., D. D. Rees, D. S. Ashton, and S. Moncada. L-Arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation. Biochem. Bio-phys. Res. Commun. 153: 1251-1256, 1988.
24. Paola, E. D. D., M. J. Vidai, and G. Nistico. L-Glutamate evokes the release of an EDRF-derived relaxing factor-like substance from the rat nucleus tractus solitarius. J. Cardiovasc. Pharmacol. 17. Suppl. 3: S269-S272, 1991.
25. Prabhakar, N. R., G. K. Kumar, C. H. Chang, F. H. Agani, and M. A. Haxhiu. Nitric oxide in the sensory function of the carotid body. Brain Res. 625: 16-22, 1993.
26. Rand, M. J. Nitrergic transmission: nitric oxide as a mediator of non-adrenergic. non-cholinergic neuro-effector transmission. Clin. Exp. Pharmacol. Physiol. 19: 147-169, 1992.
27. Rees, D. D., R. M. J. Palmer, and S. Moncada. Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc. Natl. Acad. Sci. USA 86: 3375-3378, 1989.
28. G-methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo: a role for nitric oxide in the central regulation of sympathetic tone. Circ. Res. 70: 607-611, 1992.
29. G-nitro-L-arginine methyl ester treatment in conscious rats. Hypertension Dallas 23: 982-986, 1994.
30. Togashi, H., I. Sakuma, M. Yoshioka, T. Kobayashi, H. Yasuda, A. Kitabatake, H. Saito, S. S. Gross, and R. Levi. A central nervous system action of nitric oxide in blood pressure regulation, J. Pharmacol. Exp. Ther. 262: 343-347, 1992.
31. Travagli, R. A., and R. A. Gillis. Nitric oxide-mediated excitatory effect on neurons of dorsal motor nucleus of vagus. Am. J. Physiol. 266 (Gastrointest. Liver Physiol. 29): G154-G160, 1994.
32. Traystman, R. J., L. E. Moore, M. A. Helfaer, S. Davis, K. Banasiak, M. Williams, and P. D. Hurn. Nitro-L-arginine analogues. Dose- and time-related nitric oxide synthase inhibition in brain. Stroke 26: 864-869, 1995.
33. Vasquez, E. C., R. S. Cunha, and A. M. Cabral. Baroreceptor reflex function in rats submitted to chronic inhibition of nitric oxide synthesis. Braz. J. Med. Biol. Res. 27: 767-774, 1994.
34. Zanzinger, J., J. Czachurski, and H. Seller. Inhibition of sympathetic vasoconstriction is a major principle of vasodilation by nitric oxide in vivo. Circ. Res. 75: 1073-1077, 1994.