-
1
-
-
0021180180
-
-
1. (a) Iwasaki, S.; Kobayashi, H.; Furukawa, J.; Namikoshi, M.; Okuda, S.; Sato, Z.; Matsuda, I.; Noda, T. J. Antibiot. 1984, 37, 354.
-
(1984)
J. Antibiot.
, vol.37
, pp. 354
-
-
Iwasaki, S.1
Kobayashi, H.2
Furukawa, J.3
Namikoshi, M.4
Okuda, S.5
Sato, Z.6
Matsuda, I.7
Noda, T.8
-
2
-
-
0022459992
-
-
(b) Kiyoto, S.; Kawai, Y.; Kawakita, T.; Kino, E.; Okuhara, M.; Uchida, I.; Tanaka, H.; Hashimoto, M.; Terano, H.; Kohsaka, M.; Aoki, H.; Imanika, H. J. Antibiot. 1986, 39, 762.
-
(1986)
J. Antibiot.
, vol.39
, pp. 762
-
-
Kiyoto, S.1
Kawai, Y.2
Kawakita, T.3
Kino, E.4
Okuhara, M.5
Uchida, I.6
Tanaka, H.7
Hashimoto, M.8
Terano, H.9
Kohsaka, M.10
Aoki, H.11
Imanika, H.12
-
3
-
-
0023133165
-
-
(c) Takahashi, M.; Iwasaki, S.; Kobayashi, H.; Okuda, S.; Murai, T.; Sato, Y.; Haraguchi-Hiraoka, T.; Nagano, H. J. Antibiot. 1987,40, 66.
-
(1987)
J. Antibiot.
, vol.40
, pp. 66
-
-
Takahashi, M.1
Iwasaki, S.2
Kobayashi, H.3
Okuda, S.4
Murai, T.5
Sato, Y.6
Haraguchi-Hiraoka, T.7
Nagano, H.8
-
4
-
-
0026483483
-
-
2. Hendriks, H. R.; Plowman, J.; Berger, D. P.; Paull, K. D.; Fiebig, H. H.; Fodstad, O.; Dreef-van der Meulen, H. C.; Henrar, R. E. C.; Pinedo, H. M.; Schwartsmann, G. Ann. Oncol. 1992, 3, 755.
-
(1992)
Ann. Oncol.
, vol.3
, pp. 755
-
-
Hendriks, H.R.1
Plowman, J.2
Berger, D.P.3
Paull, K.D.4
Fiebig, H.H.5
Fodstad, O.6
Dreef-Van Der Meulen, H.C.7
Henrar, R.E.C.8
Pinedo, H.M.9
Schwartsmann, G.10
-
5
-
-
9044229142
-
-
3. (a) Hanauske, A. R.; Catimel, G.; Aamdal, S.; Huinink, W. T.; Paridaens, R.; Pavlidis, N.; Kaye, S. B.; Tevelde, A.; Wanders, J.; Verweij, J. Br. J. Cancer 1996, 73, 397.
-
(1996)
Br. J. Cancer
, vol.73
, pp. 397
-
-
Hanauske, A.R.1
Catimel, G.2
Aamdal, S.3
Huinink, W.T.4
Paridaens, R.5
Pavlidis, N.6
Kaye, S.B.7
Tevelde, A.8
Wanders, J.9
Verweij, J.10
-
6
-
-
0030067375
-
-
(b) Verweij, J.; Wanders, J.; Gil, J.; Schoffski, P.; Catimel, G.; Tevelde, A.; Demulder, P. H. M. Br. J. Cancer 1996, 73, 400.
-
(1996)
Br. J. Cancer
, vol.73
, pp. 400
-
-
Verweij, J.1
Wanders, J.2
Gil, J.3
Schoffski, P.4
Catimel, G.5
Tevelde, A.6
Demulder, P.H.M.7
-
7
-
-
0030032650
-
-
(c) Kaplan, S.; Hanauske, A. R.; Pavlidis, N.; Bruntsch, U.; Tevelde, A.; Wanders, J.; Heinrich, B.; Verweij, J. Br. J. Cancer 1996, 73, 403.
-
(1996)
Br. J. Cancer
, vol.73
, pp. 403
-
-
Kaplan, S.1
Hanauske, A.R.2
Pavlidis, N.3
Bruntsch, U.4
Tevelde, A.5
Wanders, J.6
Heinrich, B.7
Verweij, J.8
-
8
-
-
0027480114
-
-
4. For total syntheses of rhizoxin, see: (a) Nakada, M.; Kobayashi, S.; Iwasaki, S.; Ohno, M. Tetrahedron Lett. 1993, 34, 1035.
-
(1993)
Tetrahedron Lett.
, vol.34
, pp. 1035
-
-
Nakada, M.1
Kobayashi, S.2
Iwasaki, S.3
Ohno, M.4
-
9
-
-
0027535385
-
-
(b) Nakada, M.; Kobayashi, S.; Shibasaki, M.; Iwasaki, S.; Ohno, M. Tetrahedron Lett. 1993, 34, 1039. For total syntheses of rhizoxin D, see:
-
(1993)
Tetrahedron Lett.
, vol.34
, pp. 1039
-
-
Nakada, M.1
Kobayashi, S.2
Shibasaki, M.3
Iwasaki, S.4
Ohno, M.5
-
10
-
-
0029033724
-
-
(c) Kende, A. S.; Blass, B. E.; Henry, J. R. Tetrahedron Lett. 1995, 36, 4741.
-
(1995)
Tetrahedron Lett.
, vol.36
, pp. 4741
-
-
Kende, A.S.1
Blass, B.E.2
Henry, J.R.3
-
11
-
-
0030839481
-
-
(d) Williams, D. R.; Werner, K. M.; Feng, B. Tetrahedron Lett, 1997, 38, 6825.
-
(1997)
Tetrahedron Lett
, vol.38
, pp. 6825
-
-
Williams, D.R.1
Werner, K.M.2
Feng, B.3
-
12
-
-
0026647544
-
-
5. For synthetic efforts directed at rhizoxin, see: (a) Rama Rao, A. V.; Sharma, G. V. M.; Bhanu, M. N. Tetrahedron Lett. 1992, 33, 3907.
-
(1992)
Tetrahedron Lett.
, vol.33
, pp. 3907
-
-
Rama Rao, A.V.1
Sharma, G.V.M.2
Bhanu, M.N.3
-
13
-
-
0027472990
-
-
(b) Rama Rao, A. V.; Bhanu, M. N.; Sharma, G. V. M. Tetrahedron Lett. 1993, 34, 707.
-
(1993)
Tetrahedron Lett.
, vol.34
, pp. 707
-
-
Rama Rao, A.V.1
Bhanu, M.N.2
Sharma, G.V.M.3
-
16
-
-
0029937762
-
-
(e) Keck, G. E.; Savin, K. A.; Weglarz, M. A.; Cressman, E. N. K. Tetrahedron Lett. 1996, 37, 3291.
-
(1996)
Tetrahedron Lett.
, vol.37
, pp. 3291
-
-
Keck, G.E.1
Savin, K.A.2
Weglarz, M.A.3
Cressman, E.N.K.4
-
18
-
-
0029094722
-
-
(g) Provencal, D. P.; Gardelli, C.; Lafontaine, J. A.; Leahy, J. W. Tetrahedron Lett. 1995, 36, 6033.
-
(1995)
Tetrahedron Lett.
, vol.36
, pp. 6033
-
-
Provencal, D.P.1
Gardelli, C.2
Lafontaine, J.A.3
Leahy, J.W.4
-
19
-
-
0030768734
-
-
(h) White, J. D.; Nylund, C. S.; Green, N. J. Tetrahedron Lett. 1997, 38, 7329.
-
(1997)
Tetrahedron Lett.
, vol.38
, pp. 7329
-
-
White, J.D.1
Nylund, C.S.2
Green, N.J.3
-
20
-
-
0030770653
-
-
(i) White, J. D.; Holoboski, M. A.; Green, N. J. Tetrahedron Lett. 1997, 38, 7333.
-
(1997)
Tetrahedron Lett.
, vol.38
, pp. 7333
-
-
White, J.D.1
Holoboski, M.A.2
Green, N.J.3
-
23
-
-
0001538420
-
-
8. (a) Burke, S. D.; Fobare, W. F.; Pacofsky, G. J. J. Org. Chem. 1983, 48, 5221.
-
(1983)
J. Org. Chem.
, vol.48
, pp. 5221
-
-
Burke, S.D.1
Fobare, W.F.2
Pacofsky, G.J.3
-
24
-
-
0010647746
-
-
The diastereomeric ratio of this reaction can be improved to 30:1 using diastereomerically pure substrate prepared by enzymatic hydrolysis of the derived acetates of 5 and its epimer
-
(b) The diastereomeric ratio of this reaction can be improved to 30:1 using diastereomerically pure substrate prepared by enzymatic hydrolysis of the derived acetates of 5 and its epimer.
-
-
-
-
26
-
-
2142858450
-
-
(b) The absolute stereochemistry at C(15) in 12 was determined by the modified Mosher method: Ohtani, I.; Kusumi, T.; Kashman, Y.; Kakisawa, H. J. Am. Chem. Soc. 1991, 113, 4092.
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 4092
-
-
Ohtani, I.1
Kusumi, T.2
Kashman, Y.3
Kakisawa, H.4
-
29
-
-
0029893354
-
-
11. For synthesis of trisubstituted olefins via the Horner-Wadsworth-Emmons reaction, see: (a) White, J. D.; Jeffrey, S. C. J. Org. Chem. 1996, 61, 2600.
-
(1996)
J. Org. Chem.
, vol.61
, pp. 2600
-
-
White, J.D.1
Jeffrey, S.C.2
-
31
-
-
0029791607
-
-
12. (a) Scarlato, G. R.; DeMattei, .F. A.; Chong, L. S.; Ogawa, A. K.; Lin, M. R.; Armstrong, R. W. J. Org. Chem. 1996, 61, 6139.
-
(1996)
J. Org. Chem.
, vol.61
, pp. 6139
-
-
Scarlato, G.R.1
Demattei, F.A.2
Chong, L.S.3
Ogawa, A.K.4
Lin, M.R.5
Armstrong, R.W.6
-
32
-
-
0010689789
-
-
4b is shown below: (equation presented)
-
4b is shown below: (equation presented)
-
-
-
-
33
-
-
0020444481
-
-
13. For applications of the Horner-Wadsworth-Emmons reaction in diene synthesis, see: (a) Roush, W. R.; Peseckis, S. M. Tetrahedron Lett. 1982, 23, 4879.
-
(1982)
Tetrahedron Lett.
, vol.23
, pp. 4879
-
-
Roush, W.R.1
Peseckis, S.M.2
-
35
-
-
0010690550
-
-
note
-
+) 553.3403, found 553.3382.
-
-
-
-
36
-
-
0000036757
-
-
Trost, B. M.; Fleming, I., Eds.; Pergamon Press: Oxford
-
15. (a) Lee, D. G.; Chen, T. in Comprehensive Organic Synthesis; Trost, B. M.; Fleming, I., Eds.; Pergamon Press: Oxford, 1991, Vol. 7, pp 541-591.
-
(1991)
Comprehensive Organic Synthesis
, vol.7
, pp. 541-591
-
-
Lee, D.G.1
Chen, T.2
-
37
-
-
0027997412
-
-
(b) Ley, S. V.; Norman, J.; Griffith, W. P.; Marsden, S. P. Synthesis 1994, 639.
-
(1994)
Synthesis
, pp. 639
-
-
Ley, S.V.1
Norman, J.2
Griffith, W.P.3
Marsden, S.P.4
-
38
-
-
0029933368
-
-
16. Bellingham, R.; Jarowiski, K.; Kocienski, P.; Martin, V. Synthesis 1996, 285.
-
(1996)
Synthesis
, pp. 285
-
-
Bellingham, R.1
Jarowiski, K.2
Kocienski, P.3
Martin, V.4
-
39
-
-
0010730836
-
-
note
-
+) 437.0967, found 437.0978.
-
-
-
|