Prolonged activation of the mitogen-activated protein kinase pathway promotes DNA synthesis in primary hepatocytes from p21(Cip-WAF1)-null mice, but not in hepatocytes from p16(INK4a)-null mice

Biochemical Journal

Volumn 336, Issue 3, 1998, Pages 551-560

  Auer, Kelly L ^a   Park, Jong Sung ^a   Seth, Prem ^b   Coffey, Robert J ^c   Darlington, Gretchen ^d   Abo, Arie ^e   Mcmahon, Martin ^f   Depinho, Ronald A ^g   Fisher, Paul B ^h   Dent, Paul ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c VANDERBILT UNIVERSITY   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e ONYX PHARMACEUTICALS   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g HARVARD MEDICAL SCHOOL   (United States)

^h The New York Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYTAMOXIFEN; CYCLIN DEPENDENT KINASE INHIBITOR; ESTROGEN RECEPTOR; GUANOSINE TRIPHOSPHATASE; HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P16; PROTEIN P21; RAF PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME INHIBITION; GENE DELETION; GENE INDUCTION; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALIA;

EID: 0032535711     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3360551     Document Type: Article

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