-
1
-
-
10544223268
-
Synergy in protein engineering: Mutagenic manipulation of protein structure to simplify semisynthesis
-
Woods, A.C., Guillemette, J.G., Pasrrish, J.C., Smith, M. & Wallace, C.J.A. (1996). Synergy in protein engineering: mutagenic manipulation of protein structure to simplify semisynthesis. J. Biol. Chem. 271, 32008-32015.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32008-32015
-
-
Woods, A.C.1
Guillemette, J.G.2
Pasrrish, J.C.3
Smith, M.4
Wallace, C.J.A.5
-
2
-
-
0029108642
-
Probing protein structure and function with an expanded genetic code
-
Cornish, V.W., Mendel, D. & Schultz, P.G. (1995). Probing protein structure and function with an expanded genetic code. Angew. Chem. Int. Ed. Engl. 34, 621-633.
-
(1995)
Angew. Chem. Int. Ed. Engl.
, vol.34
, pp. 621-633
-
-
Cornish, V.W.1
Mendel, D.2
Schultz, P.G.3
-
3
-
-
0026857064
-
Construction of protein analogues by site-specific condensation of unprotected peptides
-
Gaertner, H.F., Rose, K., Cotton, R., Timms, D., Gamble R. & Offord, R.E. (1992). Construction of protein analogues by site-specific condensation of unprotected peptides. Bioconjugate Chem. 3, 262-268.
-
(1992)
Bioconjugate Chem.
, vol.3
, pp. 262-268
-
-
Gaertner, H.F.1
Rose, K.2
Cotton, R.3
Timms, D.4
Gamble, R.5
Offord, R.E.6
-
4
-
-
0026674590
-
Functional role of heme ligation in cytochrome c
-
Wallace, C.J.A. & Clark-Lewis, I. (1992). Functional role of heme ligation in cytochrome c. J. Biol. Chem. 267, 3852-3861.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 3852-3861
-
-
Wallace, C.J.A.1
Clark-Lewis, I.2
-
5
-
-
0026525457
-
Constructing proteins by dovetailing unprotected synthetic peptides: Backbone-engineered HIV protease
-
Schnölzer, M. & Kent, S.B.H. (1992). Constructing proteins by dovetailing unprotected synthetic peptides: backbone-engineered HIV protease. Science 256, 221-225.
-
(1992)
Science
, vol.256
, pp. 221-225
-
-
Schnölzer, M.1
Kent, S.B.H.2
-
6
-
-
0001385018
-
Synthesis of a 39-peptide and a 25-peptide by thiol-capture ligations: Observation of a 40-fold rate acceleration of the intramolecular O,N-acyl transfer reaction between peptide fragments bearing only cysteine protecting groups
-
Kemp, D.S. & Carey, R.I. (1993). Synthesis of a 39-peptide and a 25-peptide by thiol-capture ligations: observation of a 40-fold rate acceleration of the intramolecular O,N-acyl transfer reaction between peptide fragments bearing only cysteine protecting groups. J. Org. Chem. 58, 2216-2222.
-
(1993)
J. Org. Chem.
, vol.58
, pp. 2216-2222
-
-
Kemp, D.S.1
Carey, R.I.2
-
7
-
-
0028231302
-
Facile synthesis of homogeneous artificial proteins
-
Rose, K. (1994). Facile synthesis of homogeneous artificial proteins. J. Am. Chem. Soc. 116, 30-33.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 30-33
-
-
Rose, K.1
-
8
-
-
12044253737
-
Chemical ligation approach to form a peptide bond between unprotected peptide segments. Concept and model study
-
Liu, C.-F. &Tam, J.P. (1994). Chemical ligation approach to form a peptide bond between unprotected peptide segments. Concept and model study. J. Am. Chem. Soc. 116, 4149-4153.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 4149-4153
-
-
Liu, C.-F.1
Tam, J.P.2
-
9
-
-
0028831838
-
Chemoselective ligation of multifunctional peptides to topological templates via thioether formation for TASP synthesis
-
Nefzi, A., Sun, X. & Mutter, M. (1995). Chemoselective ligation of multifunctional peptides to topological templates via thioether formation for TASP synthesis. Tetrahedron Lett. 36, 229-230.
-
(1995)
Tetrahedron Lett.
, vol.36
, pp. 229-230
-
-
Nefzi, A.1
Sun, X.2
Mutter, M.3
-
10
-
-
0028308549
-
Chemo-enzymatic backbone engineering of proteins
-
Gaertner, H.F., Offord, R.E., Cotton, R., Timms, D., Camble, R. & Rose, K. (1994). Chemo-enzymatic backbone engineering of proteins. J. Biol. Chem. 269, 7224-7230.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 7224-7230
-
-
Gaertner, H.F.1
Offord, R.E.2
Cotton, R.3
Timms, D.4
Camble, R.5
Rose, K.6
-
11
-
-
0028518514
-
A designed peptide ligase for total synthesis of ribonuclease A with unnatural catalytic residues
-
Jackson, D.Y., Burnier, J., Quan, C., Stanley, M., Tom, J. & Wells, J.A. (1994). A designed peptide ligase for total synthesis of ribonuclease A with unnatural catalytic residues. Science 266, 243-247.
-
(1994)
Science
, vol.266
, pp. 243-247
-
-
Jackson, D.Y.1
Burnier, J.2
Quan, C.3
Stanley, M.4
Tom, J.5
Wells, J.A.6
-
12
-
-
0028577295
-
Subtiligase: A tool for semisynthesis of proteins
-
Chang, T.K., Jackson, D.Y., Burnier, J.P. & Wells, J.A. (1994). Subtiligase: a tool for semisynthesis of proteins. Proc. Natl Acad. Sci. USA 91, 12544-12548.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 12544-12548
-
-
Chang, T.K.1
Jackson, D.Y.2
Burnier, J.P.3
Wells, J.A.4
-
13
-
-
0030936614
-
Enzymatic glycoprotein synthesis: Preparation of ribonuclease glycoforms via enzymatic glycopeptide condensation and glycosylation
-
Witte, K., Sears, P., Martin, R. & Wong, C.H. (1997). Enzymatic glycoprotein synthesis: preparation of ribonuclease glycoforms via enzymatic glycopeptide condensation and glycosylation. J. Am. Chem. Soc. 119, 2114-2118.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 2114-2118
-
-
Witte, K.1
Sears, P.2
Martin, R.3
Wong, C.H.4
-
14
-
-
0032499752
-
Expressed protein ligation: A general method for protein engineering
-
Muir, T.W., Sondhi, D. & Cole, P.A. (1998). Expressed protein ligation: a general method for protein engineering. Proc. Natl Acad. Sci. USA 95, 6705-6710.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 6705-6710
-
-
Muir, T.W.1
Sondhi, D.2
Cole, P.A.3
-
15
-
-
0032568924
-
Expressed protein ligation, a novel method for studying protein-protein interactions in transcription
-
Severinov, K. & Muir, T.W. (1998). Expressed protein ligation, a novel method for studying protein-protein interactions in transcription. J. Biol. Chem. 273, 16205-16209.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16205-16209
-
-
Severinov, K.1
Muir, T.W.2
-
16
-
-
0344351815
-
Semi-synthesis of cytotoxic proteins using a modified protein splicing element
-
in press
-
Evans, T.C.Jr, Benner, J. & Xu, M.-Q. (1998). Semi-synthesis of cytotoxic proteins using a modified protein splicing element. Protein Sci. in press.
-
(1998)
Protein Sci.
-
-
Evans Jr., T.C.1
Benner, J.2
Xu, M.-Q.3
-
17
-
-
0031244525
-
Protein splicing and autoproteolysis mechanisms
-
Perler, F.B., Xu, M.-Q. & Paulus, H. (1997). Protein splicing and autoproteolysis mechanisms. Curr. Opin. Chem. Biol. 1, 292-299.
-
(1997)
Curr. Opin. Chem. Biol.
, vol.1
, pp. 292-299
-
-
Perler, F.B.1
Xu, M.-Q.2
Paulus, H.3
-
18
-
-
0023889559
-
Chemical synthesis of peptides and proteins
-
Kent, S.B.H. (1988). Chemical synthesis of peptides and proteins. Annu. Rev. Biochem. 57, 957-989.
-
(1988)
Annu. Rev. Biochem.
, vol.57
, pp. 957-989
-
-
Kent, S.B.H.1
-
19
-
-
0029645122
-
A chemical approach to the construction of multimeric protein assemblies
-
Muir, T.W. (1995). A chemical approach to the construction of multimeric protein assemblies. Structure 3, 649-652.
-
(1995)
Structure
, vol.3
, pp. 649-652
-
-
Muir, T.W.1
-
20
-
-
0030691875
-
Rapid in situ neutralization protocols for Boc and Fmoc solid-phase chemistries
-
Alewood, P., Alewood, D., Miranda, L., Love, S., Meutermans, W. & Wilson, D. (1997). Rapid in situ neutralization protocols for Boc and Fmoc solid-phase chemistries. Methods Enzymol. 289, 14-29.
-
(1997)
Methods Enzymol.
, vol.289
, pp. 14-29
-
-
Alewood, P.1
Alewood, D.2
Miranda, L.3
Love, S.4
Meutermans, W.5
Wilson, D.6
-
21
-
-
0027373903
-
Convergent solid-phase peptide synthesis
-
Lloyd-Williams, P., Albericio, F. & E. Giralt, (1993). Convergent solid-phase peptide synthesis. Tetrahedron 48, 11065-11133.
-
(1993)
Tetrahedron
, vol.48
, pp. 11065-11133
-
-
Lloyd-Williams, P.1
Albericio, F.2
Giralt, E.3
-
22
-
-
0027944205
-
Synthesis of proteins by native chemical ligation
-
Dawson, P.E., Muir, T.W., Clark-Lewis, I. & Kent, S.B.H. (1994). Synthesis of proteins by native chemical ligation. Science 266, 776-779.
-
(1994)
Science
, vol.266
, pp. 776-779
-
-
Dawson, P.E.1
Muir, T.W.2
Clark-Lewis, I.3
Kent, S.B.H.4
-
23
-
-
0029559773
-
Peptide synthesis using unprotected peptides through orthogonal coupling methods
-
Tam, J.P., Lu, Y.-A., Liu, C.-F. & Shao, J. (1995). Peptide synthesis using unprotected peptides through orthogonal coupling methods. Proc. Natl Acad. Sci. USA 92, 12485-12489.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 12485-12489
-
-
Tam, J.P.1
Lu, Y.-A.2
Liu, C.-F.3
Shao, J.4
-
24
-
-
0030822919
-
Total chemical synthesis of enzymatically active human type II secretory phopholipase A(2)
-
Hackeng, T.M., Mounier, C.M., Bon, C., Dawson, P.E., Griffin J.H. & Kent, S.B.H. (1997). Total chemical synthesis of enzymatically active human type II secretory phopholipase A(2). Proc. Natl Acad. Sci. USA 94, 7845-7850.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 7845-7850
-
-
Hackeng, T.M.1
Mounier, C.M.2
Bon, C.3
Dawson, P.E.4
Griffin, J.H.5
Kent, S.B.H.6
-
25
-
-
0030973396
-
Modulation in native chemical ligation through the use of thiol additives
-
Dawson, P.E., Churchill, M.J., Ghadiri, M.R. & Kent, S.B.H. (1997). Modulation in native chemical ligation through the use of thiol additives. J. Am. Chem. Soc. 119, 4325-4329.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 4325-4329
-
-
Dawson, P.E.1
Churchill, M.J.2
Ghadiri, M.R.3
Kent, S.B.H.4
-
26
-
-
0029847275
-
Comparative total synthesis of turkey ovomucoid third domain by both stepwise solid phase synthesis and native chemical ligation
-
Lu, W., Qasim, M.A. & Kent, S.B.H. (1996). Comparative total synthesis of turkey ovomucoid third domain by both stepwise solid phase synthesis and native chemical ligation. J. Am. Chem. Soc. 118, 8518-8523.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 8518-8523
-
-
Lu, W.1
Qasim, M.A.2
Kent, S.B.H.3
-
27
-
-
0031894588
-
Chemical ligation of unprotected peptides directly from a solid support
-
Camarero, J.A., Cotton, G.C., Adeva, A. & Muir, T.W. (1998). Chemical ligation of unprotected peptides directly from a solid support. J. Peptide Res. 51, 303-316.
-
(1998)
J. Peptide Res.
, vol.51
, pp. 303-316
-
-
Camarero, J.A.1
Cotton, G.C.2
Adeva, A.3
Muir, T.W.4
-
28
-
-
0030482408
-
The leucine zipper domain controls the orientation of AP-1 in the NFAT·AP-1·DNA complex
-
Erlandson, D.A., Chytil, M. & Verdine, G.L. (1996). The leucine zipper domain controls the orientation of AP-1 in the NFAT·AP-1·DNA complex. Chem. Biol. 3, 981-991.
-
(1996)
Chem. Biol.
, vol.3
, pp. 981-991
-
-
Erlandson, D.A.1
Chytil, M.2
Verdine, G.L.3
-
29
-
-
0025226104
-
Protein splicing converts the yeast TFP1 gene product to the 69-kD subunit of the vacuolar H+-adenosine triphosphatase
-
Kane, P.M., Yamashiro, C.T., Wolczyk, D.F., Neff, N., Goebl, M. & Stevens, T.H. (1990). Protein splicing converts the yeast TFP1 gene product to the 69-kD subunit of the vacuolar H+-adenosine triphosphatase. Science 250, 651-657.
-
(1990)
Science
, vol.250
, pp. 651-657
-
-
Kane, P.M.1
Yamashiro, C.T.2
Wolczyk, D.F.3
Neff, N.4
Goebl, M.5
Stevens, T.H.6
-
30
-
-
0028214350
-
Protein splicing elements: Inteins and exteins - A definition of terms and recommended nomenclature
-
Perler, F.B., et al., & Belford, M. (1994). Protein splicing elements: inteins and exteins - a definition of terms and recommended nomenclature. Nucleic Acids Res. 22, 1125-1127.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 1125-1127
-
-
Perler, F.B.1
Belford, M.2
-
31
-
-
0029838842
-
The mechanism of protein splicing and its modulation by mutation
-
Xu, M.-Q. & Perler, F.B. (1996). The mechanism of protein splicing and its modulation by mutation. EMBO J. 15, 5146-5153.
-
(1996)
EMBO J.
, vol.15
, pp. 5146-5153
-
-
Xu, M.-Q.1
Perler, F.B.2
-
32
-
-
0030012109
-
Protein splicing: Evidence of an N-O acyl rearrangement as the initial step in the splicing process
-
Shao, Y., Xu, M.-Q. & Paulus, H. (1996). Protein splicing: evidence of an N-O acyl rearrangement as the initial step in the splicing process. Biochemistry 35, 3810-3815.
-
(1996)
Biochemistry
, vol.35
, pp. 3810-3815
-
-
Shao, Y.1
Xu, M.-Q.2
Paulus, H.3
-
33
-
-
0029834656
-
Protein splicing involving the Saccharomyces cerevisiae VMA intein: The steps in the splicing pathway, side reactions leading to protein cleavage, and establishment of an in vitro splicing system
-
Chong, S., Shao, Y., Paulus, H., Benner, J., Perler, F.B. & Xu, M.-Q. (1996). Protein splicing involving the Saccharomyces cerevisiae VMA intein: the steps in the splicing pathway, side reactions leading to protein cleavage, and establishment of an in vitro splicing system. J. Biol. Chem. 271, 22159-22168.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22159-22168
-
-
Chong, S.1
Shao, Y.2
Paulus, H.3
Benner, J.4
Perler, F.B.5
Xu, M.-Q.6
-
34
-
-
0031975772
-
Crystal structure of GyrA intein from Mycobacterium xenopi reveals structural basis of protein splicing
-
Klabunde, T., Sharma, S., Telenti, A., Jacobs , W.R., Jr. & Sacchettini, J.C. (1998). Crystal structure of GyrA intein from Mycobacterium xenopi reveals structural basis of protein splicing. Nat. Struct. Biol. 5, 31-36.
-
(1998)
Nat. Struct. Biol.
, vol.5
, pp. 31-36
-
-
Klabunde, T.1
Sharma, S.2
Telenti, A.3
Jacobs Jr., W.R.4
Sacchettini, J.C.5
-
35
-
-
17744415288
-
Single column purification of free recombinant proteins using a self-cleavable affinity tag derived from a protein splicing element
-
Chong, S., et al., & Xu, M.-Q. (1997). Single column purification of free recombinant proteins using a self-cleavable affinity tag derived from a protein splicing element. Gene 192, 271-281.
-
(1997)
Gene
, vol.192
, pp. 271-281
-
-
Chong, S.1
Xu, M.-Q.2
-
36
-
-
0031034930
-
Crystal structure of the Src family tyrosine kinase Hck
-
Sicheri, F., Moarefi, I. & Kuriyan, J. (1997). Crystal structure of the Src family tyrosine kinase Hck. Nature 385, 602-609.
-
(1997)
Nature
, vol.385
, pp. 602-609
-
-
Sicheri, F.1
Moarefi, I.2
Kuriyan, J.3
-
37
-
-
0031025991
-
Three-dimensional structure of the tyrosine kinase c-Src
-
Xu, W., Harrison, S.C. & Eck, M.J. (1997). Three-dimensional structure of the tyrosine kinase c-Src. Nature 385, 595-602.
-
(1997)
Nature
, vol.385
, pp. 595-602
-
-
Xu, W.1
Harrison, S.C.2
Eck, M.J.3
-
38
-
-
0032481347
-
Control of protein splicing by intein fragment reassembly
-
Southworth, M.W., Adam, E., Panne, D., Byer, R., Kautz, R. & Perler, F.B. (1998). Control of protein splicing by intein fragment reassembly. EMBO J. 17, 918-926.
-
(1998)
EMBO J.
, vol.17
, pp. 918-926
-
-
Southworth, M.W.1
Adam, E.2
Panne, D.3
Byer, R.4
Kautz, R.5
Perler, F.B.6
-
39
-
-
0032579457
-
Molecular dissection of the Mycobacterium tuberculosis RecA intein: Design of a minimal intein and of a trans-splicing system involving two intein fragments
-
Shingledecker, K., Jiang, S.-Q. & Paulus, H. (1998). Molecular dissection of the Mycobacterium tuberculosis RecA intein: design of a minimal intein and of a trans-splicing system involving two intein fragments. Gene 207, 187-195.
-
(1998)
Gene
, vol.207
, pp. 187-195
-
-
Shingledecker, K.1
Jiang, S.-Q.2
Paulus, H.3
-
40
-
-
0032584098
-
Protein slicing in trans by purified N- and C-terminal fragments of the Mycobacterium tuberculosis RecA intein
-
Mills, K.V., Lew, B.M., Jiang, S.-Q. & Paulus, H. (1998). Protein slicing in trans by purified N- and C-terminal fragments of the Mycobacterium tuberculosis RecA intein. Proc. Natl Acad. Sci. USA 95, 3343-3548.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 3343-3548
-
-
Mills, K.V.1
Lew, B.M.2
Jiang, S.-Q.3
Paulus, H.4
-
41
-
-
0032503612
-
Segmental isotope labeling for protein NMR using peptide splicing
-
Yamazaki, T., et al., & Nakamura, H. (1998). Segmental isotope labeling for protein NMR using peptide splicing. J. Am. Chem. Soc. 120, 5591-5592.
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 5591-5592
-
-
Yamazaki, T.1
Nakamura, H.2
-
42
-
-
0030210936
-
A new intein in cyanobacteria and its influence for the spread of inteins
-
Pietrokovski, S., (1996). A new intein in cyanobacteria and its influence for the spread of inteins. Trends Genet. 12, 287-288.
-
(1996)
Trends Genet.
, vol.12
, pp. 287-288
-
-
Pietrokovski, S.1
-
43
-
-
0030761813
-
The Mycobacterium xenopt GyrA protein splicing element: Characterization of a minimal intein
-
Telenti, A., Southworth, M., Alcaide, F., Daugelat, S., Jacobs, W.R.Jr. & Perler, F.B. (1997). The Mycobacterium xenopt GyrA protein splicing element: characterization of a minimal intein. J. Bacteriol. 179, 6378-6382.
-
(1997)
J. Bacteriol.
, vol.179
, pp. 6378-6382
-
-
Telenti, A.1
Southworth, M.2
Alcaide, F.3
Daugelat, S.4
Jacobs Jr., W.R.5
Perler, F.B.6
-
44
-
-
0030711495
-
Protein synthesis by chemical ligation of unprotected peptides in aqueous solution
-
Muir, T.W., Dawson, P.E. & Kent, S.B.H. (1997). Protein synthesis by chemical ligation of unprotected peptides in aqueous solution. Methods Enzymol. 289, 266-298.
-
(1997)
Methods Enzymol.
, vol.289
, pp. 266-298
-
-
Muir, T.W.1
Dawson, P.E.2
Kent, S.B.H.3
-
45
-
-
0030897311
-
Synthesis and application of unprotected cyclic peptides as building blocks for peptide dendrimers
-
Zhang, L. & Tam, J.P. (1997). Synthesis and application of unprotected cyclic peptides as building blocks for peptide dendrimers. J. Am. Chem. Soc. 119, 2363-2370.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 2363-2370
-
-
Zhang, L.1
Tam, J.P.2
-
46
-
-
1542468131
-
Chemoselective backbone cyclization of unprotected peptides
-
Camarero, J.A. & Muir, T.W. (1997). Chemoselective backbone cyclization of unprotected peptides. J. Chem. Soc. Chem. Commun. 1369-1370.
-
(1997)
J. Chem. Soc. Chem. Commun.
, pp. 1369-1370
-
-
Camarero, J.A.1
Muir, T.W.2
-
47
-
-
0032536553
-
Chemical synthesis of a circular protein domain: Evidence for folding-assisted cyclization
-
Camarero, J.A., Pavel, J. & Muir, T.W. (1998). Chemical synthesis of a circular protein domain: evidence for folding-assisted cyclization. Angew. Chem. Int. Ed. 37, 347-349.
-
(1998)
Angew. Chem. Int. Ed.
, vol.37
, pp. 347-349
-
-
Camarero, J.A.1
Pavel, J.2
Muir, T.W.3
|