IL-4 upregulates tenascin synthesis in scleroderma and healthy skin fibroblasts

Journal of Investigative Dermatology

Volumn 107, Issue 6, 1996, Pages 856-859

  Makhluf, Huda A ^a   Stepniakowska, Joanna ^a   Hoffman, Stanley ^a   Smith, Edwin ^a   LeRoy, E Carwile ^a   Trojanowska, Maria ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

bFGF; PDGF; TGF

Indexed keywords

CYTOKINE; FIBROBLAST GROWTH FACTOR; GAMMA INTERFERON; GROWTH FACTOR; INTERLEUKIN 1; INTERLEUKIN 4; INTERLEUKIN 6; PLATELET DERIVED GROWTH FACTOR; TENASCIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SCLERODERMA; SKIN FIBROBLAST;

EID: 0029856134     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12331160     Document Type: Article

References (20)

1. Chiquet-Ehrismann R, Kalla P, Pearson CA: Participation of tenascin and transforming growth factor-beta in reciprocal epithelial-mesenchymal interactions of MCF7 cells and fibroblasts. Cancer Res 49:4322-4325, 1989
2. Claman HN: On scleroderma. Mast cells, endothelial cells, and fibroblasts. JAMA 262:1206-1209, 1989
3. Erickson HP, Bourdon MA: Tenascin: an extracellular matrix protein prominent in specialized embryonic tissues and tumors. Annu Rev Cell Biol 5:71-92, 1989
4. Fagundus DM, LeRoy EC: Cytokines and systemic sclerosis. Clin Dermatol 12:407-417, 1994
5. Gailit J, Clark RA: Wound repair in the context of extracellular matrix. Curr Opin Cell Biol 6:717-725, 1994
6. Gruber BL: Mast cells: accessory cells which potentiate fibrosis. Int Rev Immunol 12:259-279, 1995
7. Koukoulis GK, Gould VE, Bhattacharyya A, Gould JE, Howeedy AA, Virtanen I: Tenascin in normal, reactive, hyperplastic, and neoplastic tissues: biologic and pathologic implications. Hum Pathol 22:636-643, 1991
8. La Fleur DW, Fagin JA, Forrester JS, Rubin SA, Sharifi BG: Cloning and characterization of alternatively spliced isoforms of rat tenascin. Platelet-derived growth factor-BB markedly stimulates expression of spliced variants of tenascin mRNA in arterial smooth muscle cells. J Biol Chem 269:20757-20763, 1994
9. Lacour JP, Vitetta A, Chiquet-Ehrismann R, Pisani A, Ortonne JP: Increased expression of tenascin in the dermis in scleroderma. Br J Dermatol 127:328-334, 1992
10. Lightner VA, Gumkowski F, Bigner DD, Erickson HP: Tenascin/hexabrachion in human skin: biochemical identification and localization by light and electron microscopy. J Cell Biol 108:2483-2493, 1989
11. McCachren SS, Lightner VA: Expression of human tenascin in synovitis and its regulation by interleukin-1. Arthritis Rheum 35:1185-1196, 1992
12. Needleman BW, Wigley FM, Stair RW: Interleukin-1, interleukin-2, interleukin-4, interleukin-6, tumor necrosis factor alpha, and interferon-gamma levels in sera from patients with scleroderma. Arthritis Rheum 35:67-72, 1992
13. Pearson CA, Pearson D, Shibahara S, Hofsteenge J, Chiquet-Ehrismann R: Tenascin: cDNA cloning and induction by TGF-beta. EMBO J 7:2977-2982, 1988
14. Rettig WJ, Erickson HP, Albino AP, Garin-Chesa P: Induction of human tenascin (neuronectin) by growth factors and cytokines: cell type-specific signals and signalling pathways. J Cell Sci 107:487-497, 1994
15. Rettig WJ, Garin-Chesa P: Cell type-specific control of human neuronectin secretion by polypeptide mediators and phorbol ester. J Histochem Cytochem 37:1777-1786, 1989
16. Salter DM: Tenascin is increased in cartilage and synovium from arthritic knees. Br J Rheumatol 132:780-786, 1993
17. Sharifi BG, La Fleur DW, Pirola CJ, Forrester JS, Fagin JA: Angiotensin II regulates tenascin gene expression in vascular smooth muscle cells. J Biol Chem 267:23910-23915, 1992
18. Tucker RP, Hammarback JA, Jenrath DA, Mackie EJ, Xu Y: Tenascin expression in the mouse: in situ localization and induction in vitro by bFGF. J Cell Sci 104:69-76, 1993
19. Whitby DJ, Ferguson MW: The extracellular matrix of lip wounds in fetal, neonatal and adult mice. Development 112:651-668, 1991
20. Yamakage A, Kikuchi K, Smith EA, LeRoy EC, Trojanowska M: Selective upregulation of platelet-derived growth factor a receptors by transforming growth factor B in scleroderma fibroblasts. J Exp Med 175:1227-1234, 1992