A solution-phase combinatorial parallel synthesis of 3β-amido-3α- hydroxy 5α-androstane-17-ones

Tetrahedron Letters

Volumn 39, Issue 24, 1998, Pages 4151-4154

  Maltais, René ^a   Poirier, Donald ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA AMIDO 3ALPHA HYDROXY 5ALPHA ANDROSTANE 17 ONE DERIVATIVE; AMINE; ANDROSTANE DERIVATIVE; ETHYLENE OXIDE; UNCLASSIFIED DRUG;

ACYLATION; DRUG SYNTHESIS; NOTE; REACTION ANALYSIS;

EID: 0032507931     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00772-2     Document Type: Article

References (23)

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22. 22. Typically, 30 mg of amine 3 was added to a 10 mL syringe loaded with silica gel (2 mL) and the compound was eluted using 3 mL of hexane / ethyl acetate (1:1) followed by 5 mL of chloroform / methanol (9:1).
23. 23. Same procedure as note 22 except that 10 mL of hexane / ethyl acetate (8:2) was used as eluent.