Telomere length regulation - A view from the individual chromosome perspective

Experimental Cell Research

Volumn 244, Issue 1, 1998, Pages 268-274

  Slijepcevic, Predrag ^a,b  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b BRUNEL UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA POLYMERASE;

ANIMAL CELL; ARTICLE; CENTROMERE; CHO CELL; CHROMOSOME; EVOLUTION; GENE EXPRESSION; HUMAN; HUMAN CELL; KARYOTYPE; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; TELOMERE;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; MAMMALIA;

EID: 0032505687     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1998.4185     Document Type: Article

References (38)

1. Zakian, V. A. (1995). Telomeres: Beginning to understand the end. Science 270, 1601-1607.
2. Kirk, K. E., Harmon, B. P., Reichardt, I. K., Sedat, J. W., and Blackburn, E. H. (1997). Block in anaphase chromosome separation caused by a telomerase template mutation. Science 275, 1478-1481.
3. de Lange, T. (1998). Ending up with the right partner. Nature 392, 753-754.
4. Boulton, S. J., and Jackson, S. P. (1996). Identification of a Saccharomyces cerevisiae Ku80 homologue: Roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acid Res. 24, 4639-4648.
5. Gravel, S., Larrivee, M., Labrecque, P., and Wellinger, R. J. (1998). Yeast Ku as a regulator of chromosomal DNA end structure. Science 280, 741-744.
6. Nugent, C. I., Bosco, G., Ross, L. O., Evans, S. K., Salinger, A. P., Moore, J. K., Haber, J. E., and Lundblad, V. (1998). Telomere maintenance is dependent on activities required for end repair of double-strand breaks. Curr. Biol. 8, 657-660.
7. Harley, C. B. (1995). Telomeres and aging. In "Telomeres" (E. H. Blackburn and C. W. Greider, Eds.), pp. 247-263, Cold Spring Harbor Press, New York.
8. Counter, C. M., Avillion, A. A., LeFeuvre, C. E., Stewart, N. G., Greider, C. W., Harley, C. B., and Bacchetti, S. (1992). Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11, 1921-1929.
9. Kim, N. W., Piatyszek, M. A., Prowse, K., Harley, C. B., West, M. D., Ho, P. L. C., Covielo, G. M., Wright, W. E., Weinrich, S. C., and Shay, J. W. (1994). Specific association of human telomerase activity with immortal cells and cancer cells. Science 270, 2011-2015.
10. Blasco, M. A., Lee, H., Hande, M. P., Samper, E., Lansdorp, P. M., DePinho, R. A., and Greider, C. W. (1997). Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91, 25-34.
11. Zakian, V. A. (1997). Life and cancer without telomerase. Cell 91, 1-3.
12. Bodnar, A. G., Ouellette, M., Frolkis, M., Holt, S. E., Chiu, C., Morin, G. B., Harley, C. B., Shay, J. W., Lichtsteiner, S., and Wright, E. W. (1998). Extension of life-span by introduction of telomerase into normal human cells. Science 279, 349-352.
13. Bryan, T. M., Englezou, A., Gupta, J., Bacchetti, S., and Reddel, R. R. (1995). Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J. 17, 4240-4248.
14. Bryan, T. M., Marusic, L., Bacchetti, S., Namba, M., and Reddel, R. R. (1997). The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit. Hum. Mol. Genet. 6, 921-926.
15. Bryan, T. M., Englezou, A., Dalla-Pozza, L., Dunham, M. A., and Reddel, R. R. (1997). Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nature Med. 3, 1271-1274.
16. Martens, U. M. M., Zijlmans, M. J. M., Poon, S. S. S., Dragowska, W., Yui, J., Chavez, E. A., Ward, R. K., and Lansdorp, P. M. (1998). Short telomeres on human chromosome 17p. Nature Genet. 18, 76-80.
17. Lingner, J., Cooper, J. P., and Cech, T. R. (1995). Telomerase and DNA end replication: No longer a lagging strand problem? Science 269, 1533-1534.
18. Wellinger, R. J., Ethier, K., Labrecque, P., and Zakian, V. A. (1996). Evidence for a new step in telomere maintenance. Cell 85, 423-433.
19. Makarov, V. L., Hirose, Y., and Langmore, J. P. (1997). Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell 88, 657-666.
20. Greider, C. W. (1995). Telomerase biochemistry and regulation. In "Telomeres" (E. H. Blackburn and C. W. Greider, Eds.), pp. 35-68, Cold Spring Harbor Press, New York.
21. Biessman, H., and Mason, J. M. (1997). Telomere maintenance without telomerase. Chromosoma 106, 63-69.
22. Marcand, S., Gilson, E., and Shore, D. (1997). A protein-counting mechanism for telomere length regulation in yeast. Science 275, 986-990.
23. Cooper, J. P., Nimmo, E. R., Allshire, R. C., and Cech, T. R. (1997). Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature 385, 744-747.
24. van Steensel, B., and de Lange, T. (1997). Control of telomere length by the human telomeric protein TRF1. Nature 385, 740-743.
25. van Steensel, B., Smogorzewska, A., and de Lange, T. (1998). TRF2 protects human telomeres from end-to-end fusions. Cell 92, 401-413.
26. 3 repeats. Proc. Natl. Acad. Sci. USA 94, 7423-7428.
27. de Lange, T. (1995). Telomere dynamics and genome instability in human cancer. In "Telomeres" (E. H. Blackburn and C. W. Greider, Eds.), pp. 265-295, Cold Spring Harbor Press, New York.
28. Kipling, D., Ackford, H. E., Taylor, B. A., and Cooke, H. J. (1991). Mouse minor satellite DNA genetically maps to the centromere and is physically linked to the proximal telomere. Genomics 11, 235-241.
29. Slijepcevic, P., Hande, M. P., Bouffler, S. D., Lansdorp, P. M., and Bryant, P. E. (1997). Telomere length, chromatin structure and chromosome fusigenic potential. Chromosoma 106, 413-421.
30. Slijepcevic, P., and Natarajan, A. T. (1994). Distribution of radiation-indiced G1 exchange and terminal deletion break-points in Chinese hamster chromosomes as detected by G-banding. Int. J. Radiat. Biol. 66, 747-755.
31. Flint, J., Bates, G. P., Clark, K., Dorman, A., Willingham, D., Roe, B. A., Micklem, G., Higgs, D. R., and Louis, E. J. (1997). Sequence comparison of human and yeast telomeres identifies structurally distinct subtelomeric domains. Hum. Mol. Genet. 6, 1305-1314.
32. Lima-de-Faria, A. (1983). "Molecular Evolution and Organization of the Chromosome," pp. 1-1186, Elsevier, Amsterdam.
33. Shore, D. (1995). Telomere position effects and transcriptional silencing in the yeast Saccharomyces cerevisiae. In "Telomeres" (E. H. Blackburn and C. W. Greider, Eds.), pp. 139-191, Cold Spring Harbor Press, New York.
34. Enomoto, S., Longtine, M. S., and Berman, J. (1994). TEL+CEN antagonism on plasmids involves telomere repeat sequences tracts and gene products that interact with chromosomal telomeres. Chromosoma 103, 237-250.
35. Dernburg, A. F., Sedat, J. W., Zacheus, W., and Bass, H. W. (1995). Cytology of telomeres. In "Telomeres" (E. H. Blackburn and C. W. Greider, Eds.), pp. 295-335, Cold Spring Harbor Press, New York.
36. Cooper, J. P., Watanabe, Y., and Nurse, P. (1998). Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination. Nature 392, 828-831.
37. Nimmo, E., Pidoux, A. L., Perry, P. E., and Allshire, R. C. (1998). Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe. Nature 392, 825-828.
38. Lima-de-Faria, A., and Bose, S. (1962). The role of telomeres at anaphase. Chromosoma 13, 315-327.