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Volumn 39, Issue 28, 1998, Pages 5125-5128

Towards an asymmetric synthesis of ADDA conjugates

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM DERIVATIVE; CYANOGINOSIN; DIPEPTIDE; GLUTAMIC ACID; NODULARIN; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR;

EID: 0032499986     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00946-0     Document Type: Article
Times cited : (19)

References (34)
  • 2
    • 0010521980 scopus 로고    scopus 로고
    • note
    • 3. Microcystins in which the glutamic acid carboxyl residue of microcystin LR Ib has been esterified are essentially non-toxic when compared to microcystin LR Ib in the same laboratory animal study. See ref. 2 and references cited therein.
  • 3
    • 0010446409 scopus 로고    scopus 로고
    • note
    • 4. Microcystins related to microcystin LR Ib in which the C-9 methoxy group of the ADDA residue is replaced with hydroxy or acetoxy show slightly reduced toxicity in laboratory animal tests. Microcystins or nodularins in which the C-6,7 double bond of the ADDA residue has been isomerised to the Z-isomer are essentially non-toxic in the same animal study. See ref. 2 and references cited therein.
  • 5
    • 0000727123 scopus 로고    scopus 로고
    • 6. The use of activated β-lactams in amide bond formation has been reviewed. Ojima, I. and Delaloge, F. Chem. Soc. Rev., 1997, 26, 377.
    • (1997) Chem. Soc. Rev. , vol.26 , pp. 377
    • Ojima, I.1    Delaloge, F.2
  • 9
    • 4243967712 scopus 로고    scopus 로고
    • PhD thesis, Oxford University, 1990. We thank Prof. E.J. Thomas (Manchester, UK) for providing extracts from this thesis and Prof A. Kende (Rochester, USA) for providing unpublished experimental details
    • 10. Chem. Abs. 116: 20822m. Roe, J.M., PhD thesis, Oxford University, 1990. We thank Prof. E.J. Thomas (Manchester, UK) for providing extracts from this thesis and Prof A. Kende (Rochester, USA) for providing unpublished experimental details.
    • Chem. Abs. , vol.16
    • Roe, J.M.1
  • 25
    • 0010441860 scopus 로고    scopus 로고
    • 1H n.m.r. of alcohol 15
    • 1H n.m.r. of alcohol 15
  • 26
    • 33947085552 scopus 로고
    • (b) The enantiomeric excess of alcohol 15 was determined by Mosher's method [J. Am. Chem. Soc. 1973, 95, 512].
    • (1973) J. Am. Chem. Soc. , vol.95 , pp. 512
  • 31
    • 0010444302 scopus 로고    scopus 로고
    • E,E-4 was separated from E,Z-4 by careful silica gel chromatography
    • 20. E,E-4 was separated from E,Z-4 by careful silica gel chromatography.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.