Inhibition of mSOS-activity by binding of phosphatidylinositol 4,5-P2 to the mSOS pleckstrin homology domain

Oncogene

Volumn 16, Issue 18, 1998, Pages 2303-2310

  Jefferson, Anne Bennett ^a   Klippel, Anke ^a   Williams, Lewis T ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Phosphatidylinositol 4,5P2; Pleckstrin homology domain; Ras; SOS

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; NEOMYCIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHATIDYLSERINE; PLECKSTRIN; PROTEIN P21;

ARTICLE; BINDING AFFINITY; PRIORITY JOURNAL;

EID: 0032493134     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1201891     Document Type: Article

References (41)

1. Aronheim A, Engelberg D, Li N, al-Alawi N, Schlessinger J and Karin M. (1994). Cell, 78, 949-961.
2. Bowtell D, Fu P, Simon M and Senior P. (1992). Proc. Nutl Acad. Sci. USA, 89, 6511-6515.
3. Buday L and Downward J. (1993). Cell, 73, 611-620.
4. Byrne JL, Paterson HF and Marshall CJ. (1996). Oncogene, 13, 2055-2065.
5. Carpenter CL and Cantley LC. (1996). Curr. Opin. Cell. Biol., 8, 153-158.
6. Chen R-H, Corbalan-Garcia S, and Bar-Sagi D. (1997). EMBO J. 16, 1351-1359.
7. Cullen PJ, Hsuan JJ, Truong O, Letcher AJ, Jackson TR, Dawson AP and Irvine RF. (1995). Nature, 376, 527-530.
8. Ferguson KM, Lemmon MA, Sigler PB and Schlessinger J. (1995). Nat. Struct. Biol., 2, 715-718.
9. Font de Mora, J, Guerrero C, Mahadevan D, Coque JJR, Rojas JM, Esteban LM, Rebecchi M and Santos E. (1996). J. Biol. Chem., 271, 18272-18276.
10. Franke TF, Kaplan DR, Cantley LC and Toker A. (1997). Science, 275, 665-668.
11. Gibson TJ, Hyvonen M, Musacchio A, Saraste M and Birney E. (1994). Trends Biochem. Sci. 19, 349-353.
12. Harlan JE, Hajduk PJ, Yoon HS and Fesik SW. (1994). Nature, 371, 168-170.
13. Haslam RJ, Koide HB and Hemmings BA. (1993). Nature. 363, 309-310.
14. Hu Q, Klippel A, Muslin AJ, Fantl WJ and Williams LT. (1995). Science, 268, 100-102.
15. Hyvonen M, Macias MJ, Nilges M, Oschkinat H, Saraste M and Wilmanns M. (1995). EMBO J., 14, 4676-4685.
16. Ingley E and Hemmings BA. (1994). J. Cell. Biochem., 56, 436-443.
17. Janmey PA, Iida K, Yin HL and Stossel TP. (1987). J. Biol. Chem., 262, 12228-12236.
18. Karlovich CA, Bonfini L, McCollam L, Rogge RD, Daga A, Czech MP and Banerjee U. (1995). Science, 268, 576-579.
19. Kavanaugh WM and Williams LT. (1994). Science. 266, 1862-1865.
20. Klippel A, Kavanaugh WM, Pot D and Williams LT. (1997). Mol. Cell. Biol., 17, 338-344.
21. Kubiseski TJ, Chook YM, Parris WE, Rozakis-Adcock M and Pawson T. (1997). J. Biol. Chem., 272, 1799-1804.
22. Lemmon MA, Ferguson KM and Schlessinger J. (1996). Cell. 85, 621-624.
23. Lodhi. S, Weiner ND and Schacht J. (1979). Biochim. Biophs. Acta, 557, 1-8.
24. Mahadevan D, Thanki N, Singh J, McPhic P, Zangrilli D, Wang LM, Guerrero C, LeVine HR, Humblet C., Saldanha J. et al., (1995). Biochemistry, 34, 9111-9117.
25. Marshall CJ. (1996). Curr. Opin. Cell. Biol., 8, 197-204.
26. Mayer BJ, Ren R, Clark KL and Baltimore D. (1993). Cell. 73, 629-630.
27. McCollam L, Bonfini L, Karlovich CA, Conway BR, Kozma LM, Banerjee U and Czech MP. (1995). J. Biol. Chem., 270, 15954-15957.
28. Medema RH and Bos JL. (1993). Crit. Rev. Oncog., 4, 615-661.
29. Musacchio A, Gibson T, Rice P, Thompson J and Saraste M. (1993). Trends Biochem. Sci., 18, 343-348.
30. Pitcher JA, Touhara K, Payne ES and Lefkowitz RJ. (1995). J. Biol. Chem., 270, 11707-11710.
31. Porfiri E, Evans T, Chardin P and Hancock JF. (1994). J. Biol. Chem., 269, 22672-22677.
32. Rameh LE, Arvidsson A, Carraway KL, Couvillon AD, Rathbun G, Crompton A, VanRenterghem B, Czech MP, Ravichandran KS, Burakoff SJ, Wang D, Chen C and Cantley LC. (1997). J. Biol. Chem., 272, 22059-22066.
33. Rodriguez-Viciana P, Warne PH, Vanhaesebroeck B, Waterfield MD and Downward J. (1996). EMBO J., 15, 2442-2451.
34. Rozakis-Adcock M, Fernley R, Wade J, Pawson T and Bowtell D. (1993). Nature, 363, 83-85.
35. Shaw G. (1996). Bioessays, 18, 35-46.
36. Stern MJ, Marengere LE, Daly RJ, Lowenstein EJ, Kokel M, Batzer A, Olivier P, Pawson T and Schlessinger J. (1993). Mol. Biol. Cell. 4, 1175-1188.
37. Tsukada S, Simon MI, Witte ON and Katz A. (1994). Proc. Natl. Acad. Sci. USA, 91, 11256-1260.
38. Wang DS and Chen CS. (1996). J. Org. Chem., 61, 5905-5910.
39. Wang W, Fisher EM, Jia Q, Dunn JM, Porfiri E, Downward J and Egan SE. (1995). Natl. Genet., 10, 294-300.
40. Welham MJ, Duronio V, Leslie KB, Bowtell D and Schrader JW. (1994). J. Biol. Chem., 269, 21165-21176.
41. Yao L, Kawakami Y and Kawakami T. (1994). Proc. Natl. Acad. Sci. USA, 91, 9175-9179.