Silencing MIG1 in Saccharomyces cerevisiae: Effects of antisense MIG1 expression and MIG1 gene disruption

Applied and Environmental Microbiology

Volumn 63, Issue 6, 1997, Pages 2366-2371

  Olsson, Lisbeth ^a   Larsen, Michael Elleskov ^a,c   Rønnow, Birgitte ^b   Mikkelsen, Jørn Dalgaard ^b   Nielsen, Jens ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b DANISCO A S   (Denmark)

^c NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BETA FRUCTOFURANOSIDASE; COMPLEMENTARY RNA; GLUCOSE; SUCROSE; TRANSCRIPTION FACTOR;

ARTICLE; GENE DISRUPTION; GENE EXPRESSION; GENE REPRESSION; NONHUMAN; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 0030921937     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/aem.63.6.2366-2371.1997     Document Type: Article

References (37)

1. Atkins, D., G. M. Arndt, and J. G. Izant. 1994. Antisense gene expression in yeast. Biol. Chem. Hoppe-Seyler 375:721-729.
2. Barford, J. P., P. K. Mwesigye, P. J. Phillips, D. Jayasuriya, and I. Blom. 1993. Further evidence of direct uptake of sucrose by Saccharomyces cerevisiae in batch culture. J. Gen. Appl. Microbiol. 39:389-394.
3. Barnett, J. A. 1981. The utilization of disaccharides and some other sugars by yeasts. Adv. Carbohydr. Chem. Biochem. 39:347-404.
4. Benthin, S., J. Nielsen, and J. Villadsen. 1992. Flow-injection analysis of micromolar concentrations of glucose and lactate in fermentation media. Anal. Chim. Acta 261:145-153.
5. Bourque, J. E. 1995. Antisense strategies for genetic manipulations in plant. Plant Sci. 105:125-149.
6. Carlson, M. 1987. Regulation of sugar utilization in Saccharomyces species. J. Bacteriol. 169:4873-4877.
7. Carlson, M., and D. Botstein. 1982. Two different regulated mRNA's with different ends encode secreted and intracellular forms of yeast invertase. Cell 28:145-154.
8. Chu, G., D. Vollrath, and R. W. Davis. 1986. Separation of large DNA molecules by contour-clamped homogeneous electric fields. Science 234: 1582-1585.
9. Elorza, M. A., J. R. Villanueva, and R. Sentandreu. 1977. The mechanism of catabolite inhibition of invertase by glucose in Saccharomyces cerevisiae. Biochim. Biophys. Acta 475:103-112.
10. Erickson, R. P., and J. G. Izant. 1992. Gene regulation: biology of antisense RNA and DNA. Raven Press, New York, N.Y.
11. Falco, S. C., and K. S. Dumas. 1985. Genetic analysis of mutants of Saccharomyces cerevisiae resistant to the herbicide sulfometuron methyl. Genetics 109:21-35.
12. Fiechter, A., and W. Seghezzi. 1992. Regulation of glucose metabolism in growing yeast cells. J. Biotechnol. 27:27-45.
13. Gancedo, J. M. 1992. Carbon catabolite repression in yeast. Eur. J. Biochem. 206:297-313.
14. Hadfield, C., B. E. Jordan, R. C. Mount, G. H. J. Pretorius, and E. Burak. 1990. G418-resistance as a dominant marker and reporter for gene expression in Saccharomyces cerevisiae. Curr. Genet. 18:303-313.
15. Johnston, M., and M. Carlson. 1992. Regulation of carbon and phosphate utilization, p. 193-281. In E. W. Jones, J. R. Pringle, and J. R. Broach (ed.), The molecular and cellular biology of the yeast Saccharomyces: gene expression, vol. 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
16. Keleher, C. A., M. J. Redd, J. Schultz, M. Carlson, and A. D. Johnson. 1992. Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68:704-719.
17. Knust, B., and D. von Wettstein. 1992. Expression and secretion of pea-seed lipoxygenase isoenzymes in Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 37:342-351.
18. Lutfiyya, L. L., and M. Johnston. 1996. Two zinc-finger-containing repressers are responsible for glucose repression of SUC2 expression. Mol. Cell. Biol. 16:4790-4797.
19. Marten, M. R., and J.-H. Seo. 1989. Localization of cloned invertase in Saccharomyces cerevisiae directed by the SUC2 and MFa1 signal sequences. Biotechnol. Bioeng. 34:1133-1139.
20. Nasr, F., A.-M. Bécam, S. C. Brown, D. De Nay, P. P. Slonimski, and C. J. Herbert. 1995. Artificial antisense RNA regulation of YBR1012 (YBR136w), an essential gene from Saccharomyces cerevisiae which is important for progression through G1/S. Mol. Gen. Genet. 249:51-57.
21. Nasr, F., A. M. Becam, P. P. Slonimski, and C. J. Herbert. 1994. YBR1012, an essential gene from Saccharomyces cerevisiae: construction of an RNA-antisense conditional allele and isolation of a multicopy suppressor. C. R. Acad. Sci. Paris Ser. III 317:607-613.
22. Nehlin, J. O., M. Carlberg, and H. Ronne. 1992. Yeast SKO1 gene encodes a bZIP protein that hinds to the CRE motif and acts as a repressor of transcription. Nucleic Acids Res. 20:5271-5278.
23. Nehlin, J. O., and H. Ronne. 1990. Yeast MIG1 repressor is related to the mammalian early growth response and Wilms tumour linger proteins. EMBO J. 9:2891-2898.
24. Patkar, A., and J.-H. Seo. 1992. Fermentation kinetics of recombinant yeast in batch and fed-batch cultures. Biotechnol. Bioeng. 40:103-109.
25. Pedersen, M. B. 1986. DNA sequence polymorphisms in the genus Saccharomyces cerevisiae. III. Restriction endonuclease fragment patterns of chromosomal regions in brewing and other yeast strains. Carlsberg Res. Commun. 51:163-183.
26. Post-Beitenmiller, M. A., R. W. Hamilton, and J. E. Hopper. 1984. Regulation of basal and induced levels of the MEL1 transcript in Saccharomyces cerevisiae. Mol. Cell. Biol. 4:1238-1245.
27. Rose, M., F. Winston, and P. Hieter. 1990. Methods in yeast genetics: a laboratory course manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
28. Rothstein, R. J. 1983. One step gene disruption in yeast. Methods Enzymol. 101:202-211.
29. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
30. Santos, E., L. Rodriguez, M. V. Elorza, and R. Sentandreu. 1982. Uptake of sucrose by Saccharomyces cerevisiae. Arch. Biochem. Biophys. 216:652-660.
31. Schmitt, M. E., T. A. Brown, and B. L. Trumpower. 1984. A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae. Nucleic Acids Res. 18:3091-3092.
32. Schwartz, D. C., and C. R. Cantor. 1984. Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis. Cell 37:67-75.
33. Struhl, K., D. T. Stinchcomb, S. Scherer, and R. W. Davis. 1979. High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules. Proc. Natl. Acad. Sci. USA 76:1035-1039.
34. Trumbly, R. J. 1992. Glucose repression in the yeast Saccharomyces cerevisiae. Mol. Microbiol. 6:15-21.
35. Vallier, L. G., and M. Carlson. 1991. New SNF genes, GAL11 and GRR1 affect SUC2 expression in Saccharomyces cerevisiae. Genetics 129:675-684.
36. Vallier, L. G., and M. Carlson. 1994. Synergistic release from glucose repression by mig1 and ssn mutations in Saccharomyces cerevisiae. Genetics 137:49-54.
37. Verduyn, C., E. Postma, W. A. Scheffers, and J. P. van Dijken. 1990. Physiology of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat cultures. J. Gen. Microbiol. 136:395-403.