Hepatocyte injury in tyrosinemia type 1 is induced by fumarylacetoacetate and is inhibited by caspase inhibitors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 16, 1998, Pages 9552-9557

  Kubo, Shuji ^a   Sun, Maosen ^a   Miyahara, Michio ^a   Umeyama, Kazuhiro ^b   Urakami, Ken Ichi ^b   Yamamoto, Tetsuro ^c   Jakobs, Cornelis ^d   Matsuda, Ichiro ^a   Endo, Fumio ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b TERUMO CORPORATION   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE PROTEINASE INHIBITOR; CYTOCHROME C; FUMARIC ACID DERIVATIVE; FUMARYLACETOACETASE;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME DEFICIENCY; GENE MUTATION; LIVER CELL DAMAGE; LIVER FAILURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TYROSINEMIA;

ACETOACETATES; AMINO ACID METABOLISM, INBORN ERRORS; ANIMALS; APOPTOSIS; CELL-FREE SYSTEM; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROME C GROUP; DISEASE MODELS, ANIMAL; LIVER; MICE; MICE, KNOCKOUT; MITOCHONDRIA, LIVER; TYROSINE;

ANIMALIA;

EID: 0032482959     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.16.9552     Document Type: Article

References (41)

1. Phaneuf, D., Lambert, M., Laframboise, R., Mitchell, G., Lettre, F. & Tanguay, R. M. (1992) J. Clin. Invest. 90, 1185-1192.
2. Mitchell, G. A., Lambert, M. & Tanguay, R. M. (1995) in The Metabolic and Molecular Basis of Inherited Disease, eds. Scriver, C. R., Beaudet, A. L., Sly, W. S. & Valle, D. (McGraw-Hill, New York), 7th Ed., pp. 1077-1106.
3. Holme, E. & Lindstedt, S. (1995) Curr. Opin. Pediatr. 7, 726-732.
4. Lindblad, B., Lindstedt, S. & Steen, G. (1977) Proc. Natl. Acad. Sci. USA 74, 4641-4645.
5. Awata, H., Endo, F. & Matsuda, I. (1994) Genomics 23, 534-539.
6. Haber, B. A., Chuang, E., Lee, W. & Taub, R. (1996) Hepatology 24, 65-71.
7. Ruppert, S., Kelsey, G., Schedl, A., Schmid, E., Thies, E. & Schütz, G. (1992) Genes Dev. 6, 1430-1443.
8. Tönjes, R. R., Xanthopoulos, K. G., Darnell, J. E., Jr., & Paul, D. (1992) EMBO J. 11, 127-133.
9. Kvittingen, E. A., Rootwelt, H., Berger, R. & Brandtzaeg, P. (1994) J. Clin. Invest. 94, 1657-1661.
10. Grompe, M., Lindstedt, S., al-Dhalimy, M., Kennaway, N. G., Papaconstantinou, J., Torres-Ramos, C. A., Ou, C. N. & Fine-gold, M. (1995) Nat. Genet. 10, 453-460.
11. Endo, F., Kubo, S., Awata, H., Kiwaki, K., Katoh, H., Kanegae, Y., Saito, I., Miyazaki, J., Yamamoto, T., Jakobs, C., Hattori, S. & Matsuda, I. (1997) J. Biol. Chem. 272, 24426-24432.
12. Gluecksohn-Waelsch, S. (1979) Cell 16, 225-237.
13. Klebig, M. L., Russell, L. B. & Rinchik, E. M. (1992) Proc. Natl. Acad. Sci. USA 89, 1363-1367.
14. Kelsey, G., Ruppert, S., Beermann, F., Grund, C., Tanguay, R. M. & Schütz, G. (1993) Genes Dev. 7, 2285-2297.
15. Grompe, M., al-Dhalimy, M., Finegold, M., Ou, C. N., Burlingame, T., Kennaway, N. G. & Soriano, P. (1993) Genes Dev. 7, 2298-2307.
16. Katoh, H., Endo, F., Suzuki, K. & Matsuda, I. (1991) Mouse Genome 89, 572.
17. Endo, F., Katoh, H., Yamamoto, S. & Matsuda, I. (1991) Am. J. Hum. Genet. 48, 704-709.
18. Kubo, S., Kiwaki, K., Awata, H., Katoh, H., Kanegae, Y., Saito, I., Yamamoto, T., Miyazaki, J., Matsuda, I. & Endo, F. (1997) Human Gene Ther. 8, 65-71.
19. Kroemer, G. (1997) Nat. Med. 3, 614-620.
20. Reed, J. C. (1997) Nature (London) 387, 773-776.
21. Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T. I., Jones, D. P. & Wang, X. (1997) Science 275, 1129-1132.
22. Kluck, R. M., Wetzel, E. B., Green, D. R. & Newmeyer, D. D. (1997) Science 215, 1132-1136.
23. Liu, X., Kim, C. N., Yang, J., Jemmerson, R. & Wang, X. (1996) Cell 86, 147-157.
24. Zou, H., Henzel, W. J., Liu, X., Lutschg, A. & Wang, X. (1997) Cell 90, 405-413.
25. Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S. & Wang, X. (1997) Cell 91, 479-489.
26. Liu, X., Zou, H., Slaughter, C. & Wang, X. (1997) Cell 89, 175-184.
27. Kiwaki, K., Kanegae, Y., Saito, I., Komaki, S., Nakamura, K., Miyazaki, J., Endo, F. & Matsuda, I. (1996) Human Gene Ther. 7, 821-830.
28. Miyazaki, J., Takai, S., Araki, K., Tashiro, F., Tominaga, A., Takatsu, K. & Yamamura, K. (1989) Gene 79, 269-277.
29. Niwa, H., Yamamura, K. & Miyazaki, J. (1991) Gene 108, 193-199.
30. Kanegae, Y., Makimura, M. & Saito, I. (1994) Jpn. J. Med. Sci. Biol. 47, 157-166.
31. Ueno, T., Miyamura, T., Saito, I. & Mizuno, K. (1993) Hum. Cell 6, 126-135.
32. Ni, R., Tomita, Y., Matsuda, K., Ichihara, A., Ishimura, K., Ogasawara, J. & Nagata, S. (1994) Exp. Cell Res. 215, 332-337.
33. Schnaitman, C. & Greenawalt, J. W. (1968) J. Cell Biol. 38, 158-175.
34. Jakobs, C., Dorland, L., Wikkerink, B., Kok, R. M., de Jong, A. P. & Wadman, S. K. (1988) Clin. Chim. Acta 171, 223-231.
35. Thornberry, N. A., Bull, H. G., Calaycay, J. R., Chapman, K. T., Howard, A. D., Kostura, M. J., Miller, D. K., Molineaux, S. M., Weidner, J. R., Aunins, J., et al. (1992) Nature (London) 356, 768-774.
36. Nicholson, D. W., Ali, A., Thornberry, N. A., Vaillancourt, J. P., Ding, C. K., Gallant, M., Gareau, Y., Griffin, P. R., Labelle, M., Lazebnik, Y. A., et al. (1995) Nature (London) 376, 37-43.
37. Lindstedt, S., Holme, E., Lock, E. A., Hjalmarson, O. & Strandvik, B. (1992) Lancet 340, 813-817.
38. Sassa, S. & Kappas, A. (1983) J. Clin. Invest. 71, 625-634.
39. Maltzman, W. & Czyzyk, L. (1984) Mol. Cell. Biol. 4, 1689-1694.
40. Kastan, M. B., Onyekwere, O., Sidransky, D., Vogelstein, B. & Craig, R. W. (1991) Cancer Res. 51, 6304-6311.
41. Shneider, B. L. (1996) Curr. Opin. Pediatr. 8, 495-501.