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Volumn 10, Issue 16, 1996, Pages 2089-2101

Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer

Author keywords

Alternative splicing; doublesex; sex determination; site specific crosslinking; SR proteins; transformer proteins

Indexed keywords

PURINE;

EID: 0029858338     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.16.2089     Document Type: Article
Times cited : (202)

References (48)
  • 1
    • 0024255702 scopus 로고
    • The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein
    • Amrein, H., M. Gorman, and R. Nöthiger. 1988. The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein. Cell 55: 1025-1035.
    • (1988) Cell , vol.55 , pp. 1025-1035
    • Amrein, H.1    Gorman, M.2    Nöthiger, R.3
  • 2
    • 0028324929 scopus 로고
    • The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2
    • Amrein, H., M.L. Hedley, and T. Maniatis. 1994. The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2. Cell 76: 735-746.
    • (1994) Cell , vol.76 , pp. 735-746
    • Amrein, H.1    Hedley, M.L.2    Maniatis, T.3
  • 3
    • 0024328766 scopus 로고
    • Sex in flies: The splice of life
    • Baker, B.S. 1989. Sex in flies: The splice of life. Nature 340: 521-524.
    • (1989) Nature , vol.340 , pp. 521-524
    • Baker, B.S.1
  • 4
    • 0026770678 scopus 로고
    • Differential binding of heterogeneous nuclear ribonucleoproteins to mRNA precursors prior to spliceosome assembly in vitro
    • Bennett, M., S. Pinol-Roma, D. Staknis, G. Dreyfuss, and R. Reed. 1992. Differential binding of heterogeneous nuclear ribonucleoproteins to mRNA precursors prior to spliceosome assembly in vitro. Mol. Cell. Biol. 12: 3165-3175.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3165-3175
    • Bennett, M.1    Pinol-Roma, S.2    Staknis, D.3    Dreyfuss, G.4    Reed, R.5
  • 5
    • 0023667001 scopus 로고
    • Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene
    • Boggs, R.T., P. Gregor, S. Idriss, J.M. Belote, and M. McKeown. 1987. Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene. Cell 50: 739-747.
    • (1987) Cell , vol.50 , pp. 739-747
    • Boggs, R.T.1    Gregor, P.2    Idriss, S.3    Belote, J.M.4    McKeown, M.5
  • 6
    • 0024539898 scopus 로고
    • Drosophila doublesex gene controls somatic sexual differentiation by producing alternative spliced mRNAs encoding related sex-specific polypeptides
    • Burtis, K.C. and B.S. Baker. 1989. Drosophila doublesex gene controls somatic sexual differentiation by producing alternative spliced mRNAs encoding related sex-specific polypeptides. Cell 56: 997-1010.
    • (1989) Cell , vol.56 , pp. 997-1010
    • Burtis, K.C.1    Baker, B.S.2
  • 7
    • 0028338991 scopus 로고
    • Characterization and cloning of the human splicing factor 9G8: A novel 35 kDa factor of the serine/arginine protein family
    • Cavaloc, Y., M. Popielaiz, J.P. Fuchs, R. Gattoni, and J. Stevenin. 1994. Characterization and cloning of the human splicing factor 9G8: A novel 35 kDa factor of the serine/arginine protein family. EMBO J. 13: 2639-2649.
    • (1994) EMBO J. , vol.13 , pp. 2639-2649
    • Cavaloc, Y.1    Popielaiz, M.2    Fuchs, J.P.3    Gattoni, R.4    Stevenin, J.5
  • 8
    • 0027532430 scopus 로고
    • Sex-specific transcriptional regulation by the male and female doublesex proteins of Drosophila
    • Coschigano, K.T. and P.C. Wensink. 1993. Sex-specific transcriptional regulation by the male and female doublesex proteins of Drosophila. Genes & Dev. 7: 42-54.
    • (1993) Genes & Dev. , vol.7 , pp. 42-54
    • Coschigano, K.T.1    Wensink, P.C.2
  • 9
    • 0027424442 scopus 로고
    • Specific commitment of different pre-mRNAs to splicing by single SR proteins
    • Fu, X.-D. 1993. Specific commitment of different pre-mRNAs to splicing by single SR proteins. Nature 343: 82-85.
    • (1993) Nature , vol.343 , pp. 82-85
    • Fu, X.-D.1
  • 10
    • 0029372979 scopus 로고
    • The superfamily of arginine/serine-rich splicing factors
    • _. 1995. The superfamily of arginine/serine-rich splicing factors. RNA 1: 663-680.
    • (1995) RNA , vol.1 , pp. 663-680
  • 11
    • 0026586528 scopus 로고
    • Isolation of a complementary DNA that encodes the mammalian splicing factor SC35
    • Fu, X.-D. and T. Maniatis. 1992. Isolation of a complementary DNA that encodes the mammalian splicing factor SC35. Science 256: 535-538.
    • (1992) Science , vol.256 , pp. 535-538
    • Fu, X.-D.1    Maniatis, T.2
  • 12
    • 0025827463 scopus 로고
    • Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators
    • Ge, H., P. Zuo, and J.L. Manley. 1991. Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators. Cell 66: 373-382.
    • (1991) Cell , vol.66 , pp. 373-382
    • Ge, H.1    Zuo, P.2    Manley, J.L.3
  • 13
    • 0025745243 scopus 로고
    • Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro
    • Hedley, M.L. and T. Maniatis. 1991. Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro. Cell 65: 579-586.
    • (1991) Cell , vol.65 , pp. 579-586
    • Hedley, M.L.1    Maniatis, T.2
  • 14
    • 0029618696 scopus 로고
    • An amino acid sequence motif sufficient for subnuclear localization of an arginine/serine-rich splicing factor
    • Hedley, M.L., H. Amrein, and T. Maniatis. 1995. An amino acid sequence motif sufficient for subnuclear localization of an arginine/serine-rich splicing factor. Proc. Natl. Acad. Sci. 92: 11524-11528.
    • (1995) Proc. Natl. Acad. Sci. , vol.92 , pp. 11524-11528
    • Hedley, M.L.1    Amrein, H.2    Maniatis, T.3
  • 15
    • 0029114121 scopus 로고
    • The Drosophila SR protein RBP1 contributes to the regulation of doublesex alternative splicing by recognizing RBP1 RNA target sequences
    • Heinrichs, V. and B.S. Baker. 1995. The Drosophila SR protein RBP1 contributes to the regulation of doublesex alternative splicing by recognizing RBP1 RNA target sequences. EMBO J. 14: 3987-4000.
    • (1995) EMBO J. , vol.14 , pp. 3987-4000
    • Heinrichs, V.1    Baker, B.S.2
  • 16
    • 0025815671 scopus 로고
    • Control of doublesex alternative splicing by transformer and transformer-2 in Drosophila
    • Hoshijima, K., K. Inoue, I. Higuchi, H. Sakamoto, and Y. Shimura. 1991. Control of doublesex alternative splicing by transformer and transformer-2 in Drosophila. Science 252: 833-836.
    • (1991) Science , vol.252 , pp. 833-836
    • Hoshijima, K.1    Inoue, K.2    Higuchi, I.3    Sakamoto, H.4    Shimura, Y.5
  • 17
    • 0027083267 scopus 로고
    • The Drosophila RNA-binding protein RBP1 is localized to transcriptionally active sites of chromosomes and shows a functional similarity to human splicing factor ASF/SF2
    • Kim, Y.J., P. Zuo, J.L. Manley, and B.S. Baker. 1992. The Drosophila RNA-binding protein RBP1 is localized to transcriptionally active sites of chromosomes and shows a functional similarity to human splicing factor ASF/SF2. Genes & Dev. 6: 2569-2579.
    • (1992) Genes & Dev. , vol.6 , pp. 2569-2579
    • Kim, Y.J.1    Zuo, P.2    Manley, J.L.3    Baker, B.S.4
  • 18
  • 19
    • 0025743575 scopus 로고
    • Functional expression of clones of human splicing factor SF2: Homology to RNA binding proteins, U1 70K, and Drosophila splicing regulators
    • Krainer, A.R., A. Mayeda, K. Kozak, and G. Binns. 1991. Functional expression of clones of human splicing factor SF2: Homology to RNA binding proteins, U1 70K, and Drosophila splicing regulators. Cell 66: 383-394.
    • (1991) Cell , vol.66 , pp. 383-394
    • Krainer, A.R.1    Mayeda, A.2    Kozak, K.3    Binns, G.4
  • 20
    • 0027143943 scopus 로고
    • A splicing enhancer in the human fibronectin alternative ED1 exon interacts with SR proteins and stimulates U2 snRNP binding
    • Lavigueur, A., H. La Branche, A.R. Kornblihtt, and B. Chabot. 1993. A splicing enhancer in the human fibronectin alternative ED1 exon interacts with SR proteins and stimulates U2 snRNP binding. Genes & Dev. 7: 2405-2417.
    • (1993) Genes & Dev. , vol.7 , pp. 2405-2417
    • Lavigueur, A.1    La Branche, H.2    Kornblihtt, A.R.3    Chabot, B.4
  • 21
    • 0028926275 scopus 로고
    • Synergistic interaction between two distinct elements of a regulated splicing enhancer
    • Lynch, K.W. and T. Maniatis. 1995. Synergistic interaction between two distinct elements of a regulated splicing enhancer. Genes & Dev. 9: 284-293.
    • (1995) Genes & Dev. , vol.9 , pp. 284-293
    • Lynch, K.W.1    Maniatis, T.2
  • 22
    • 0026034658 scopus 로고
    • Mechanisms of alternative pre-mRNA splicing
    • Maniatis, T. 1991. Mechanisms of alternative pre-mRNA splicing. Science 251:33-34.
    • (1991) Science , vol.251 , pp. 33-34
    • Maniatis, T.1
  • 23
    • 0026516573 scopus 로고
    • Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing
    • Mayeda, A., A.M. Zahler, A.R. Krainer, and M.B. Roth. 1992. Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing. Proc. Natl. Acad. Sci. 89: 1301-1304.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 1301-1304
    • Mayeda, A.1    Zahler, A.M.2    Krainer, A.R.3    Roth, M.B.4
  • 24
    • 0023921858 scopus 로고
    • Ectopic expression of the female transformer gene product leads to female differentiation of chromosomally male Drosophila
    • McKeown, M., J.M. Belote, and R.T. Boggs. 1988. Ectopic expression of the female transformer gene product leads to female differentiation of chromosomally male Drosophila. Cell 53: 887-895.
    • (1988) Cell , vol.53 , pp. 887-895
    • McKeown, M.1    Belote, J.M.2    Boggs, R.T.3
  • 25
    • 0026680843 scopus 로고
    • Site-specific modification of pre-mRNA: The 2′-hydroxyl group at the splice site
    • Moore, M. and P.A. Sharp. 1992. Site-specific modification of pre-mRNA: The 2′-hydroxyl group at the splice site. Science 256: 992-996.
    • (1992) Science , vol.256 , pp. 992-996
    • Moore, M.1    Sharp, P.A.2
  • 26
    • 0025189682 scopus 로고
    • Regulation of sex-specific RNA splicing at the Drosophila doublesex gene: Cis-acting mutations in exon sequences alter sex-specific RNA splicing patterns
    • Nagoshi, R.N. and B.S. Baker. 1990. Regulation of sex-specific RNA splicing at the Drosophila doublesex gene: cis-acting mutations in exon sequences alter sex-specific RNA splicing patterns. Genes & Dev. 4: 89-97.
    • (1990) Genes & Dev. , vol.4 , pp. 89-97
    • Nagoshi, R.N.1    Baker, B.S.2
  • 27
    • 0024294339 scopus 로고
    • The control of alternative splicing at genes regulating sexual differentiation in D. melanogaster
    • Nagoshi, R.N., M. McKeown, K.C. Burtis, J.M. Belote, and B.S. Baker. 1988. The control of alternative splicing at genes regulating sexual differentiation in D. melanogaster. Cell 53: 229-236.
    • (1988) Cell , vol.53 , pp. 229-236
    • Nagoshi, R.N.1    McKeown, M.2    Burtis, K.C.3    Belote, J.M.4    Baker, B.S.5
  • 28
    • 0028832642 scopus 로고
    • Genetic enhancement of RNA-processing defects by a dominant mutation in B52, the Drosophila gene for an SR protein splicing factor
    • Peng, X. and S.M. Mount. 1995. Genetic enhancement of RNA-processing defects by a dominant mutation in B52, the Drosophila gene for an SR protein splicing factor. Mol. Cell. Biol. 15: 6273-6282.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6273-6282
    • Peng, X.1    Mount, S.M.2
  • 29
    • 0029144216 scopus 로고
    • A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by directing interactions with an exonic enhancer
    • Ramchatesingh, J., A.M. Zahler, K.M. Neugebauer, M.B. Roth, and T.A. Cooper. 1995. A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by directing interactions with an exonic enhancer. Mol. Cell. Biol. 15: 4898-4907.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4898-4907
    • Ramchatesingh, J.1    Zahler, A.M.2    Neugebauer, K.M.3    Roth, M.B.4    Cooper, T.A.5
  • 30
    • 0024290434 scopus 로고
    • Purification and visualization of native spliceosomes
    • Reed, R., J. Griffith, and T. Maniatis. 1988. Purification and visualization of native spliceosomes. Cell 53: 949-961.
    • (1988) Cell , vol.53 , pp. 949-961
    • Reed, R.1    Griffith, J.2    Maniatis, T.3
  • 31
    • 0028046121 scopus 로고
    • The SR protein B52/SRp55 is essential for Drosophila development
    • Ring, H.Z. and J.T. Lis. 1994. The SR protein B52/SRp55 is essential for Drosophila development. Mol. Cell. Biol. 14: 7499-7506.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7499-7506
    • Ring, H.Z.1    Lis, J.T.2
  • 32
    • 0026477884 scopus 로고
    • RNA binding proteins, splice site selection and alternative pre-mRNA splicing
    • Rio, D. 1992. RNA binding proteins, splice site selection and alternative pre-mRNA splicing. Gene Expr. 2: 1-5.
    • (1992) Gene Expr. , vol.2 , pp. 1-5
    • Rio, D.1
  • 33
    • 0025931225 scopus 로고
    • A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription
    • Roth, M.B., A.M. Zahler, and J.A. Stolk. 1991. A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription. J. Cell. Biol. 115: 587-596.
    • (1991) J. Cell. Biol. , vol.115 , pp. 587-596
    • Roth, M.B.1    Zahler, A.M.2    Stolk, J.A.3
  • 34
    • 0025988927 scopus 로고
    • Regulation of doublesex premRNA processing occurs by 3′-splice site activation
    • Ryner, L.C. and B.S. Baker. 1991. Regulation of doublesex premRNA processing occurs by 3′-splice site activation. Genes & Dev 5: 2071-2085.
    • (1991) Genes & Dev , vol.5 , pp. 2071-2085
    • Ryner, L.C.1    Baker, B.S.2
  • 36
    • 0028006713 scopus 로고
    • SR proteins promote the first specific recognition of pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex
    • Staknis, D. and R. Reed. 1994. SR proteins promote the first specific recognition of pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex. Mol. Cell. Biol. 14: 7670-7682.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7670-7682
    • Staknis, D.1    Reed, R.2
  • 37
    • 0025140080 scopus 로고
    • Genetic control of sex determination in Drosophila
    • Steinmann-Zwicky, M., H. Amrein, and R. Nöthiger. 1990. Genetic control of sex determination in Drosophila. Adv. Genet. 27: 189-237.
    • (1990) Adv. Genet. , vol.27 , pp. 189-237
    • Steinmann-Zwicky, M.1    Amrein, H.2    Nöthiger, R.3
  • 38
    • 0027715743 scopus 로고
    • General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer
    • Sun, Q., A. Mayeda, R.K. Hampson, A.R. Krainer, and F.M. Rottman. 1993. General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer. Genes & Dev. 7: 2598-2608.
    • (1993) Genes & Dev. , vol.7 , pp. 2598-2608
    • Sun, Q.1    Mayeda, A.2    Hampson, R.K.3    Krainer, A.R.4    Rottman, F.M.5
  • 39
    • 0029064220 scopus 로고
    • The human splicing factors ASF/SF2 and SC35 possess different, functionally significant, RNA binding specificities
    • Tacke, R. and J.L. Manley. 1995. The human splicing factors ASF/SF2 and SC35 possess different, functionally significant, RNA binding specificities. EMBO J. 14: 3540-3551.
    • (1995) EMBO J. , vol.14 , pp. 3540-3551
    • Tacke, R.1    Manley, J.L.2
  • 40
    • 0026579802 scopus 로고
    • Positive control of pre-mRNA splicing in vitro
    • Tian, M. and T. Maniatis. 1992. Positive control of pre-mRNA splicing in vitro. Science 256: 237-240.
    • (1992) Science , vol.256 , pp. 237-240
    • Tian, M.1    Maniatis, T.2
  • 41
    • 0027185151 scopus 로고
    • A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA
    • _. 1993. A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA. Cell 74: 105-114.
    • (1993) Cell , vol.74 , pp. 105-114
  • 42
    • 0028025033 scopus 로고
    • A splicing enhancer exhibits both constitutive and regulated activities
    • _. 1994. A splicing enhancer exhibits both constitutive and regulated activities. Genes & Dev. 8: 1703-1712.
    • (1994) Genes & Dev. , vol.8 , pp. 1703-1712
  • 43
    • 0029295349 scopus 로고
    • Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways
    • Wang, J. and J.L. Manley. 1995. Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways. RNA 1: 335-346.
    • (1995) RNA , vol.1 , pp. 335-346
    • Wang, J.1    Manley, J.L.2
  • 44
    • 0027137934 scopus 로고
    • Specific interactions between proteins implicated in splice site selection and regulated alternative splicing
    • Wu, J.Y. and T. Maniatis. 1993. Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. Cell 75: 1061-1070.
    • (1993) Cell , vol.75 , pp. 1061-1070
    • Wu, J.Y.1    Maniatis, T.2
  • 45
    • 0026716104 scopus 로고
    • SR proteins: A conserved family of pre-mRNA splicing factors
    • Zahler, A.M., W.S. Lane, J.A. Stolk, and M.B. Roth. 1992. SR proteins: A conserved family of pre-mRNA splicing factors. Genes & Dev. 6: 837-847.
    • (1992) Genes & Dev. , vol.6 , pp. 837-847
    • Zahler, A.M.1    Lane, W.S.2    Stolk, J.A.3    Roth, M.B.4
  • 46
    • 0027160003 scopus 로고
    • Distinct functions of SR proteins in alternative premRNA splicing
    • Zahler, A.M., K.M. Neugebauer, W.S. Lane, and M.B. Roth. 1993. Distinct functions of SR proteins in alternative premRNA splicing. Science 260: 219-222.
    • (1993) Science , vol.260 , pp. 219-222
    • Zahler, A.M.1    Neugebauer, K.M.2    Lane, W.S.3    Roth, M.B.4
  • 47
    • 0026649523 scopus 로고
    • Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit
    • Zhang, M., P.D. Zamore, M. Carmo-Fonseca, A.I. Lamond, and M.R. Green. 1992. Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit. Proc. Natl. Acad. Sci. 89: 8769-8773.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 8769-8773
    • Zhang, M.1    Zamore, P.D.2    Carmo-Fonseca, M.3    Lamond, A.I.4    Green, M.R.5
  • 48
    • 0029665533 scopus 로고    scopus 로고
    • 35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing
    • 35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing. Genes & Dev. 10: 1356-1368.
    • (1996) Genes & Dev. , vol.10 , pp. 1356-1368
    • Zuo, P.1    Maniatis, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.