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Volumn 76, Issue 2, 1997, Pages 264-265

Phase II trial of raltitrexed ('Tomudex') in advanced small-cell lung cancer

Author keywords

Chemotherapy; Phase II study; Raltitrexed; Small cell lung cancer; Thymidylate synthase inhibitor; Tomudex; ZD1694

Indexed keywords

RALTITREXED; THYMIDYLATE SYNTHASE INHIBITOR;

EID: 0031011302     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1997.373     Document Type: Article
Times cited : (11)

References (9)
  • 2
    • 0024791358 scopus 로고
    • The design of phase II trials
    • Cullen M (1989) The design of phase II trials. Lung Cancer 5: 214-220
    • (1989) Lung Cancer , vol.5 , pp. 214-220
    • Cullen, M.1
  • 4
    • 0029931840 scopus 로고    scopus 로고
    • 'Tomudex' (ZD1694): A novel thymidylate synthase inhibitor with clinical antitumour activity in a range of solid tumours
    • Cunningham D, Zalcberg J, Smith J. Gore M, Pazdur R, Burris H, Meropol NJ, Kennealey G, Seymour L and the 'Tomudex' International Study Group (1996) 'Tomudex' (ZD1694): a novel thymidylate synthase inhibitor with clinical antitumour activity in a range of solid tumours. Ann Oncol 7: 179-182
    • (1996) Ann Oncol , vol.7 , pp. 179-182
    • Cunningham, D.1    Zalcberg, J.2    Smith, J.3    Gore, M.4    Pazdur, R.5    Burris, H.6    Meropol, N.J.7    Kennealey, G.8    Seymour, L.9
  • 5
    • 0025219280 scopus 로고
    • Evaluation of new drugs in untreated patients with small cell lung cancer - Its time has come
    • Ettinger DS (1990) Evaluation of new drugs in untreated patients with small cell lung cancer - its time has come. J Clin Oncol 8: 374-377
    • (1990) J Clin Oncol , vol.8 , pp. 374-377
    • Ettinger, D.S.1
  • 6
    • 0025997350 scopus 로고
    • ICI D1694, a quinazoline antilblate thymidylate synthase inhibitor that is a potent inhibitor of LI210 tumor cell growth in vitro and in vivo: A new agent for clinical study
    • Jackman AL, Taylor GA, Gibson W, Kimbell R, Brown M, Culvert H, Judson IR and Hughes LR (1991) ICI D1694, a quinazoline antilblate thymidylate synthase inhibitor that is a potent inhibitor of LI210 tumor cell growth in vitro and in vivo: a new agent for clinical study. Cancer Res 51: 5579-5586
    • (1991) Cancer Res , vol.51 , pp. 5579-5586
    • Jackman, A.L.1    Taylor, G.A.2    Gibson, W.3    Kimbell, R.4    Brown, M.5    Culvert, H.6    Judson, I.R.7    Hughes, L.R.8
  • 7
    • 0026543551 scopus 로고
    • Phase II trial design considerations for small cell lung cancer
    • Moore TD and Korn EL (1992) Phase II trial design considerations for small cell lung cancer. J Natl Cancer Inst 84: 150-154
    • (1992) J Natl Cancer Inst , vol.84 , pp. 150-154
    • Moore, T.D.1    Korn, E.L.2
  • 9
    • 0000154770 scopus 로고
    • Phase I trial of the new thymidylate synthase inhibitor 'Tomudex' (ZD1694) in patients with advanced malignancy
    • Sorensen JM, Jordan E, Grem JL et al (1994) Phase I trial of the new thymidylate synthase inhibitor 'Tomudex' (ZD1694) in patients with advanced malignancy (abstract 240). Ann Oncol 5 (suppl. 5): 132
    • (1994) Ann Oncol , vol.5 , Issue.5 SUPPL. , pp. 132
    • Sorensen, J.M.1    Jordan, E.2    Grem, J.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.