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Volumn 16, Issue 4, 1996, Pages 359-379

The MHC class II-associated invariant chain: A molecule with multiple roles in MHC class II biosynthesis and antigen presentation to CD4+ T cells

Author keywords

antigen presentation; CD4+ T cells; CLIP; Ii; isoforms

Indexed keywords

CD4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; T LYMPHOCYTE RECEPTOR;

EID: 0029966857     PISSN: 10408401     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (48)

References (189)
  • 1
    • 0018367950 scopus 로고
    • Detection of a common polypeptide chain in I-A and I-E subregions immunoprecipitates
    • Jones, P., Murphy, D. B., Hewgill, D., and McDevitt, H. O., Detection of a common polypeptide chain in I-A and I-E subregions immunoprecipitates, Immunochemistry, 16, 51-60, 1978.
    • (1978) Immunochemistry , vol.16 , pp. 51-60
    • Jones, P.1    Murphy, D.B.2    Hewgill, D.3    McDevitt, H.O.4
  • 2
    • 0018613819 scopus 로고
    • Analysis of HLA-D region associated molecules with monoclonal antibody
    • Charron D. J. and McDevitt, H. O., Analysis of HLA-D region associated molecules with monoclonal antibody, Proc Natl. Acad. Sci. U.S.A., 76, 6567-6571, 1979.
    • (1979) Proc Natl. Acad. Sci. U.S.A. , vol.76 , pp. 6567-6571
    • Charron, D.J.1    McDevitt, H.O.2
  • 3
    • 0024977415 scopus 로고
    • A role of Ia-associated invariant chains in antigen processing and presentation
    • Stockinger, B., Pessara, U., Lin, R. H., Habicht, J., Grez, M., and Koch, N., A role of Ia-associated invariant chains in antigen processing and presentation, Cell, 56, 683-689, 1989.
    • (1989) Cell , vol.56 , pp. 683-689
    • Stockinger, B.1    Pessara, U.2    Lin, R.H.3    Habicht, J.4    Grez, M.5    Koch, N.6
  • 6
    • 0028147578 scopus 로고
    • The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules
    • Elliott, E. A., Drake, J. R., Amigorena, S., Elsemore, J., Webster, P., Mellman, I., and Flavell, R. A., The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules, J. Exp. Med., 179, 681-694, 1994.
    • (1994) J. Exp. Med. , vol.179 , pp. 681-694
    • Elliott, E.A.1    Drake, J.R.2    Amigorena, S.3    Elsemore, J.4    Webster, P.5    Mellman, I.6    Flavell, R.A.7
  • 7
    • 0021834981 scopus 로고
    • Murine invariant chain gene: Chromosomal assignment and segregation in recombinant inbred strains
    • Richards, J. E., Pravtcheva, D. D., Day, C., Ruddle, F. H., and Jones, P. P., Murine invariant chain gene: chromosomal assignment and segregation in recombinant inbred strains, Immunogenetics, 22, 193-199, 1985.
    • (1985) Immunogenetics , vol.22 , pp. 193-199
    • Richards, J.E.1    Pravtcheva, D.D.2    Day, C.3    Ruddle, F.H.4    Jones, P.P.5
  • 9
    • 0006380659 scopus 로고
    • cDNA clone for the human invariant gamma chain of class II histocompatibility antigens and its implications for the protein structure
    • Claesson, L., Larhammar, D., Rask, L., and Peterson, P. A., cDNA clone for the human invariant gamma chain of class II histocompatibility antigens and its implications for the protein structure, Proc. Natl. Acad. Sci. U.S.A., 80, 7395-7399, 1983.
    • (1983) Proc. Natl. Acad. Sci. U.S.A. , vol.80 , pp. 7395-7399
    • Claesson, L.1    Larhammar, D.2    Rask, L.3    Peterson, P.A.4
  • 10
    • 0025257112 scopus 로고
    • Regulation of major histocompatibiity complex class II genes: X, Y and other letters of the alphabet
    • Benoist, C. and Mathis, D., Regulation of major histocompatibiity complex class II genes: X, Y and other letters of the alphabet, Anna. Rev. Immunol., 8, 681-715, 1990.
    • (1990) Anna. Rev. Immunol. , vol.8 , pp. 681-715
    • Benoist, C.1    Mathis, D.2
  • 12
    • 0022972838 scopus 로고
    • Regulation of class II gene expression: Analysis in B cell stimulatory factor I-inducible murine pre-B cell lines
    • Polla, B. S., Poljack, A., Ohara, J., Paul, W. E., and Glimcher, L. H., Regulation of class II gene expression: analysis in B cell stimulatory factor I-inducible murine pre-B cell lines, J. Immunol., 136, 3332-3337, 1986.
    • (1986) J. Immunol. , vol.136 , pp. 3332-3337
    • Polla, B.S.1    Poljack, A.2    Ohara, J.3    Paul, W.E.4    Glimcher, L.H.5
  • 13
    • 0020560102 scopus 로고
    • Interferon-γ induces enhanced expression of Ia and H-2 antigens on B lymphoid, macrophage and myeloid cell lines
    • Wong, G. H. W., Clarck-Lewis, L, McKimm-Breschkin, J. L., Harris, A. W., and Schrader, J. W., Interferon-γ induces enhanced expression of Ia and H-2 antigens on B lymphoid, macrophage and myeloid cell lines, J. Immunol, 131, 788-796, 1983.
    • (1983) J. Immunol , vol.131 , pp. 788-796
    • Wong, G.H.W.1    Clarck-Lewis, L.2    McKimm-Breschkin, J.L.3    Harris, A.W.4    Schrader, J.W.5
  • 14
    • 0021329785 scopus 로고
    • Effect of cloned interferon-γ on expression of H-2 and Ia antigens on cell lines of hemopoietic, lymphoid, epithelial, fibroblastic and neuronal origin
    • Wong, G. W. H., Clarck-Lewis, L, Harris, A. W., and Schrader, J. W., Effect of cloned interferon-γ on expression of H-2 and Ia antigens on cell lines of hemopoietic, lymphoid, epithelial, fibroblastic and neuronal origin, Eur. J. Immunol., 14, 52-60, 1984.
    • (1984) Eur. J. Immunol. , vol.14 , pp. 52-60
    • Wong, G.W.H.1    Clarck-Lewis, L.2    Harris, A.W.3    Schrader, J.W.4
  • 15
    • 0020442220 scopus 로고
    • Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity
    • Steeg, P. S., Moore, R. N., Johnson, H. M., and Oppenheim, J. J., Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity, J.Exp.Med., 156, 1780-1792, 1982.
    • (1982) J.Exp.Med. , vol.156 , pp. 1780-1792
    • Steeg, P.S.1    Moore, R.N.2    Johnson, H.M.3    Oppenheim, J.J.4
  • 16
    • 0020524896 scopus 로고
    • Induction of Ia and H-2 antigens on a macrophage cell line by immune interferon
    • King, D. P. and Jones, P. P., Induction of Ia and H-2 antigens on a macrophage cell line by immune interferon, J. Immunol., 131, 315, 1983.
    • (1983) J. Immunol. , vol.131 , pp. 315
    • King, D.P.1    Jones, P.P.2
  • 17
    • 0023009755 scopus 로고
    • Effects of interferon-γ and tumor necrosis factor-α on the expression of an MHC class II antigen on a murine macrophage cell line
    • Chang, R. J. and Lee, S. H., Effects of interferon-γ and tumor necrosis factor-α on the expression of an MHC class II antigen on a murine macrophage cell line, J. Immunol., 135, 2853-2856, 1986.
    • (1986) J. Immunol. , vol.135 , pp. 2853-2856
    • Chang, R.J.1    Lee, S.H.2
  • 19
    • 0022654204 scopus 로고
    • Differential expression of Ia and Ia-associated invariant chain in mouse tissues after in vivo treatment with IFN-gamma
    • Momburg, F., Koch, N., Moller, P., Moldenhauer, G., Butcher, G. W., and Hämmerling, G. J., Differential expression of Ia and Ia-associated invariant chain in mouse tissues after in vivo treatment with IFN-gamma, J. Immunol., 136, 940-948, 1986.
    • (1986) J. Immunol. , vol.136 , pp. 940-948
    • Momburg, F.1    Koch, N.2    Moller, P.3    Moldenhauer, G.4    Butcher, G.W.5    Hämmerling, G.J.6
  • 20
    • 0022613314 scopus 로고
    • Interferon-gamma, mitocycin C, and cycloheximide as regulatory agents of MHC class II-associated invariant chain expression
    • Rahmsdorf, H. J., Harth, N., Eades, A. M., Litfin, M., Steinmetz, M., Forni, L., and Herrlich, P., Interferon-gamma, mitocycin C, and cycloheximide as regulatory agents of MHC class II-associated invariant chain expression, J. Immunol., 136, 2293-2299, 1986.
    • (1986) J. Immunol. , vol.136 , pp. 2293-2299
    • Rahmsdorf, H.J.1    Harth, N.2    Eades, A.M.3    Litfin, M.4    Steinmetz, M.5    Forni, L.6    Herrlich, P.7
  • 21
    • 0025352678 scopus 로고
    • Tumor necrosis factor alpha regulates expression of the major histocompatibility complex class II-associated invariant chain by binding of an NF-kappa B-like factor to a promoter element
    • Pessara, U. and Koch, N., Tumor necrosis factor alpha regulates expression of the major histocompatibility complex class II-associated invariant chain by binding of an NF-kappa B-like factor to a promoter element, Mol. Cell. Biol., 10, 4146-4154, 1990.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 4146-4154
    • Pessara, U.1    Koch, N.2
  • 22
    • 0027210536 scopus 로고
    • Induction of the murine class-II antigen associated invariant chain by TNF-a is controlled by an NF-kB-like element
    • Kolk, D. P. and Floyd-Smith, G., Induction of the murine class-II antigen associated invariant chain by TNF-a is controlled by an NF-kB-like element, Gene, 126, 179-185, 1993.
    • (1993) Gene , vol.126 , pp. 179-185
    • Kolk, D.P.1    Floyd-Smith, G.2
  • 23
    • 0025277507 scopus 로고
    • Transcriptional control of the invariant chain gene involves promoter and enhancer elements common to and distinct from major histocompatibility complex class II genes
    • Zhu, L. and Jones, P. P., Transcriptional control of the invariant chain gene involves promoter and enhancer elements common to and distinct from major histocompatibility complex class II genes, Mol. Cell. Biol., 10, 3906-3916, 1990.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 3906-3916
    • Zhu, L.1    Jones, P.P.2
  • 24
    • 0025810510 scopus 로고
    • Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and form a heterodimer with c-fos
    • Ono, S. J., Liou, H. C., Davidson, R., and Strominger, J. L., Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and form a heterodimer with c-fos, Proc. Natl. Acad. Sci. U.S.A., 88, 4309-4312, 1991.
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 4309-4312
    • Ono, S.J.1    Liou, H.C.2    Davidson, R.3    Strominger, J.L.4
  • 25
    • 0024920023 scopus 로고
    • From cell code to gene code: Cytokines and transcription factors
    • Muegge, K. and Durum, S., From cell code to gene code: cytokines and transcription factors, New Biologist, 1, 239-246, 1989.
    • (1989) New Biologist , vol.1 , pp. 239-246
    • Muegge, K.1    Durum, S.2
  • 26
    • 0021233606 scopus 로고
    • Ia-negative B-cell variants revealed a coordinate regulation in the transcription of the HLA class II gene family
    • Long, E. O., Mach, B., and Accolla, R. S., Ia-negative B-cell variants revealed a coordinate regulation in the transcription of the HLA class II gene family, Immunogenetics, 19, 349-353, 1984.
    • (1984) Immunogenetics , vol.19 , pp. 349-353
    • Long, E.O.1    Mach, B.2    Accolla, R.S.3
  • 27
    • 0022413343 scopus 로고
    • The human Ia-associated invariant chain is synthesized in Ia-negative B cell variants and is not expressed on the cell surface of both Ia-negative and Ia-positive parental cells
    • Accolla, R. S., Carra, G., Buchegger, F., Carrel, S., and Mach, J. P., The human Ia-associated invariant chain is synthesized in Ia-negative B cell variants and is not expressed on the cell surface of both Ia-negative and Ia-positive parental cells, J. Immunol., 134. 3265-3271, 1985.
    • (1985) J. Immunol. , vol.134 , pp. 3265-3271
    • Accolla, R.S.1    Carra, G.2    Buchegger, F.3    Carrel, S.4    Mach, J.P.5
  • 28
    • 0024475227 scopus 로고
    • NF-KB: A pleiotropic mediator of inducible and tissue-specific gene control
    • Lenardo, M. J. and Baltimore, D., NF-KB: a pleiotropic mediator of inducible and tissue-specific gene control, Cell, 58, 227-229, 1989.
    • (1989) Cell , vol.58 , pp. 227-229
    • Lenardo, M.J.1    Baltimore, D.2
  • 29
    • 0025903720 scopus 로고
    • Correlation between invariant chain expression level and capability to present antigen to MHC class II-restricted T cells
    • Bertolino, P., Forquet, F., Pont, S., Koch, N., Gerlier, D., and Rabourdin-Combe, C., Correlation between invariant chain expression level and capability to present antigen to MHC class II-restricted T cells, Int. Immunol., 3, 435-443, 1991.
    • (1991) Int. Immunol. , vol.3 , pp. 435-443
    • Bertolino, P.1    Forquet, F.2    Pont, S.3    Koch, N.4    Gerlier, D.5    Rabourdin-Combe, C.6
  • 30
    • 0021952734 scopus 로고
    • One gene encodes two distinct Ia-associated invariant chains
    • Yamamoto, K., Koch, N., Steinmetz, M., and Hämmerling, G. J., One gene encodes two distinct Ia-associated invariant chains, J. Immunol., 134, 3461-3466, 1985.
    • (1985) J. Immunol. , vol.134 , pp. 3461-3466
    • Yamamoto, K.1    Koch, N.2    Steinmetz, M.3    Hämmerling, G.J.4
  • 31
    • 0023001316 scopus 로고
    • Two forms of the Ia antigen-associated invariant chain result from alternative initiations at two in-phase AUGs
    • Strubin, M., Long, E. O., and Mach, B., Two forms of the Ia antigen-associated invariant chain result from alternative initiations at two in-phase AUGs, Cell, 47, 619-625, 1986.
    • (1986) Cell , vol.47 , pp. 619-625
    • Strubin, M.1    Long, E.O.2    Mach, B.3
  • 32
    • 0023223411 scopus 로고
    • Four Ia invariant chain forms derive from a single gene by alternate splicing and alternate initiation of transcription/translation
    • O'Sullivan, D. M., Noonan, D., and Quarante, V., Four Ia invariant chain forms derive from a single gene by alternate splicing and alternate initiation of transcription/translation, J. Exp. Med., 166, 444-460, 1987.
    • (1987) J. Exp. Med. , vol.166 , pp. 444-460
    • O'Sullivan, D.M.1    Noonan, D.2    Quarante, V.3
  • 33
    • 0023353636 scopus 로고
    • Primary structure of the gene for the murine Ia antigen-associated invariant chains(Ii). An alternatively spliced exon encodes a cysteine-rich domain highly homologous to a repetitive sequence of thyroglobulin
    • Koch, N., Lauer, W., Habicht, J., and Dobberstein, B., Primary structure of the gene for the murine Ia antigen-associated invariant chains(Ii). An alternatively spliced exon encodes a cysteine-rich domain highly homologous to a repetitive sequence of thyroglobulin, EMBO J., 6, 1677-1683, 1987.
    • (1987) EMBO J. , vol.6 , pp. 1677-1683
    • Koch, N.1    Lauer, W.2    Habicht, J.3    Dobberstein, B.4
  • 34
    • 0019520427 scopus 로고
    • The invariant chain of murine Ia antigens: Its glycosylation, abundance and subcellular localization
    • Sung, E. and Jones, P. P., The invariant chain of murine Ia antigens: its glycosylation, abundance and subcellular localization, Mol. ImmunoL, 18, 899-913, 1981.
    • (1981) Mol. ImmunoL , vol.18 , pp. 899-913
    • Sung, E.1    Jones, P.P.2
  • 35
    • 0019962031 scopus 로고
    • Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigens
    • Kvist, S., Wiman, K., Claesson, L., Peterson, A., and Dobberstein, B., Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigens, Cell, 29, 61-69, 1982.
    • (1982) Cell , vol.29 , pp. 61-69
    • Kvist, S.1    Wiman, K.2    Claesson, L.3    Peterson, A.4    Dobberstein, B.5
  • 36
    • 0020422255 scopus 로고
    • Biosynthesis and glycosylation of the invariant chain associated with HLA-DRantigens
    • Machamer, C. E. and Cresswell, P., Biosynthesis and glycosylation of the invariant chain associated with HLA-DRantigens, J. Immunol., 129, 2564-2569, 1982.
    • (1982) J. Immunol. , vol.129 , pp. 2564-2569
    • Machamer, C.E.1    Cresswell, P.2
  • 37
    • 0025083334 scopus 로고
    • Invariant chain trimers are sequestered in the rough endoplasmic reticulum in the absence of association with HLA class II antigens
    • Marks, M. S., Blum, J. S., and Cresswell, P., Invariant chain trimers are sequestered in the rough endoplasmic reticulum in the absence of association with HLA class II antigens, J. Cell Biol., 111, 839-855, 1990.
    • (1990) J. Cell Biol. , vol.111 , pp. 839-855
    • Marks, M.S.1    Blum, J.S.2    Cresswell, P.3
  • 39
    • 0029040014 scopus 로고
    • Efficient endosomal localization of major histocompatibility complex class II-invariant chain complexes requires multimerization of the invariant chain targeting sequence
    • Arneson, L. S. and Miller, J., Efficient endosomal localization of major histocompatibility complex class II-invariant chain complexes requires multimerization of the invariant chain targeting sequence, J. Cell Biol., 129, 1217-1228, 1995.
    • (1995) J. Cell Biol. , vol.129 , pp. 1217-1228
    • Arneson, L.S.1    Miller, J.2
  • 40
    • 0026509280 scopus 로고
    • Assembly and transport properties of invariant chain trimers and HLA-DR-invariant chain complexes
    • Lamb, C. A. and Cresswell, P., Assembly and transport properties of invariant chain trimers and HLA-DR-invariant chain complexes, J. Immunol., 148, 3478-3482, 1992.
    • (1992) J. Immunol. , vol.148 , pp. 3478-3482
    • Lamb, C.A.1    Cresswell, P.2
  • 41
    • 0028233882 scopus 로고
    • Mapping functional regions in the lumenal domain of the class-II-associated invariant chain
    • Bijlmakers, M. J., Benaroch, P., and Ploegh, H. L., Mapping functional regions in the lumenal domain of the class-II-associated invariant chain, J. Exp. Med., 180, 623-629, 1994.
    • (1994) J. Exp. Med. , vol.180 , pp. 623-629
    • Bijlmakers, M.J.1    Benaroch, P.2    Ploegh, H.L.3
  • 42
    • 0027489002 scopus 로고
    • The segment of invariant chain that is critical for association with major histocompatibility complex class II molecules contains the sequence of a peptide eluted from class II polypeptides
    • Freisewinkel, I. M., Schanck, K., and Koch, N., The segment of invariant chain that is critical for association with major histocompatibility complex class II molecules contains the sequence of a peptide eluted from class II polypeptides, Proc. Natl. Acad. Sci. U.S.A., 90, 9703-9706, 1993.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 9703-9706
    • Freisewinkel, I.M.1    Schanck, K.2    Koch, N.3
  • 43
    • 0028805246 scopus 로고
    • Direct observation of disordered regions in the major histocompatibility complex class II-associated invariant chain
    • Jasanoff, A., Park, S. J., and Wiley, D. C., Direct observation of disordered regions in the major histocompatibility complex class II-associated invariant chain, Proc. Natl. Acad. Sci. U.S.A., 92, 9900-9904, 1995.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 9900-9904
    • Jasanoff, A.1    Park, S.J.2    Wiley, D.C.3
  • 44
    • 0028845966 scopus 로고
    • Evidence for invariant chain 85-101 (CLIP) binding in the antigen binding site of MHC class II molecules
    • Bangia, N. and Watts, T. H., Evidence for invariant chain 85-101 (CLIP) binding in the antigen binding site of MHC class II molecules, Int. Immunol., 7, 1585-1591, 1995.
    • (1995) Int. Immunol. , vol.7 , pp. 1585-1591
    • Bangia, N.1    Watts, T.H.2
  • 45
    • 0026088251 scopus 로고
    • Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain
    • Roche, P, A., Marks, M. S., and Cresswell, P., Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain, Nature, 354, 392-394, 1991.
    • (1991) Nature , vol.354 , pp. 392-394
    • Roche, P.A.1    Marks, M.S.2    Cresswell, P.3
  • 46
    • 0028212649 scopus 로고
    • Targeting major histocompatibility complex class II molecules to the cell surface by invariant chain allows antigen presentation upon recycling
    • Nijenhuis, M., Calafat, J., Kuijpers, K. C., Janssen, H., De Haas, M., Nordeng, T. W., Bakke, O., and Neefjes, J. J., Targeting major histocompatibility complex class II molecules to the cell surface by invariant chain allows antigen presentation upon recycling, EurJ. Immunol., 24, 873-883, 1994.
    • (1994) EurJ. Immunol. , vol.24 , pp. 873-883
    • Nijenhuis, M.1    Calafat, J.2    Kuijpers, K.C.3    Janssen, H.4    De Haas, M.5    Nordeng, T.W.6    Bakke, O.7    Neefjes, J.J.8
  • 47
    • 0028057880 scopus 로고
    • Association with BiP and aggregation of class II MHC molecules synthesized in the absence of invariant chain
    • Bonnerot, C., Marks, M. S., Cosson, P., Robertson, E. J., Bikoff, E. K., Germain, R. N., and Bonifacino, J. S., Association with BiP and aggregation of class II MHC molecules synthesized in the absence of invariant chain, EMBO J., 13, 934-944, 1994.
    • (1994) EMBO J. , vol.13 , pp. 934-944
    • Bonnerot, C.1    Marks, M.S.2    Cosson, P.3    Robertson, E.J.4    Bikoff, E.K.5    Germain, R.N.6    Bonifacino, J.S.7
  • 48
    • 0028152358 scopus 로고
    • A role for calnexin (IP90) in the assembly of class II MHC molecules
    • Andersen, K. S. and Cresswell, P., A role for calnexin (IP90) in the assembly of class II MHC molecules, EMBO J., 13, 675-682, 1994.
    • (1994) EMBO J. , vol.13 , pp. 675-682
    • Andersen, K.S.1    Cresswell, P.2
  • 49
    • 0020460539 scopus 로고
    • Analysis of murine Ia antigen glycosylation by lectin affinity chromatography. I-Ak α chain subspecies and β are each glycosylated differently
    • Cowan, E. P., Cummings, R. D., Schwartz, B. D., and Cullen, S. E., Analysis of murine Ia antigen glycosylation by lectin affinity chromatography. I-Ak α chain subspecies and β are each glycosylated differently, J. Biol. Chem., 257, 11241-11248, 1982.
    • (1982) J. Biol. Chem. , vol.257 , pp. 11241-11248
    • Cowan, E.P.1    Cummings, R.D.2    Schwartz, B.D.3    Cullen, S.E.4
  • 51
    • 0022642799 scopus 로고
    • Fatty acylation of murine α, β and Ii chains
    • Simonis, S. and Cullen, S., Fatty acylation of murine α, β and Ii chains, J. Immunol., 136, 2962-2967, 1986.
    • (1986) J. Immunol. , vol.136 , pp. 2962-2967
    • Simonis, S.1    Cullen, S.2
  • 52
    • 0022999809 scopus 로고
    • The HLA-D-associated invariant chain binds palmitic acid at the cysteine adjacent to the membrane segment
    • Koch, N. and Hämmerling, G. J., The HLA-D-associated invariant chain binds palmitic acid at the cysteine adjacent to the membrane segment, J. Biol. Chem., 261, 3434-3440, 1986.
    • (1986) J. Biol. Chem. , vol.261 , pp. 3434-3440
    • Koch, N.1    Hämmerling, G.J.2
  • 53
    • 0022354023 scopus 로고
    • Ia-associated invariant chain is fatty acylated before addition of sialic acid
    • Koch, N. and Hämmerling, G. J., Ia-associated invariant chain is fatty acylated before addition of sialic acid, Biochemistry, 24, 6185-6190, 1985.
    • (1985) Biochemistry , vol.24 , pp. 6185-6190
    • Koch, N.1    Hämmerling, G.J.2
  • 54
    • 0021354880 scopus 로고
    • Monensin prevents terminal glycosylation of the N- and O-linked oligosaccharides of the HLA-DR-associated invariant chain and inhibits its dissociation from the alpha-beta chain complex
    • Machamer, C. E. and Cresswell, P., Monensin prevents terminal glycosylation of the N- and O-linked oligosaccharides of the HLA-DR-associated invariant chain and inhibits its dissociation from the alpha-beta chain complex, Proc. Natl. Acad. Sci U.S.A., 81, 1287-1291, 1984.
    • (1984) Proc. Natl. Acad. Sci U.S.A. , vol.81 , pp. 1287-1291
    • Machamer, C.E.1    Cresswell, P.2
  • 56
    • 0024469867 scopus 로고
    • The invariant chain is a phosphorylated subunit of class II molecules
    • Spiro, R. C. and Quaranta, V., The invariant chain is a phosphorylated subunit of class II molecules, J. Immunol., 143, 2589-2594, 1989.
    • (1989) J. Immunol. , vol.143 , pp. 2589-2594
    • Spiro, R.C.1    Quaranta, V.2
  • 57
    • 0021087493 scopus 로고
    • Identification of a new component in the murine Ia molecular complex
    • Sant, A. J., Schwartz, B. D., and Cullen, S., Identification of a new component in the murine Ia molecular complex, J. Exp. Med., 158, 1979-1982, 1983.
    • (1983) J. Exp. Med. , vol.158 , pp. 1979-1982
    • Sant, A.J.1    Schwartz, B.D.2    Cullen, S.3
  • 58
    • 0022332685 scopus 로고
    • Invariant chain is the core protein of the Ia-associated chondroitin sulfate proteoglycan
    • Sant, A. J., Cullen, S. E., Giacoletto, K. S., and Schwartz, B. D., Invariant chain is the core protein of the Ia-associated chondroitin sulfate proteoglycan, J. Exp. Med., 162, 1916-1934, 1985.
    • (1985) J. Exp. Med. , vol.162 , pp. 1916-1934
    • Sant, A.J.1    Cullen, S.E.2    Giacoletto, K.S.3    Schwartz, B.D.4
  • 60
    • 0023974392 scopus 로고
    • Identification of the glycosaminoglycan-attachment site of mouse invariant-chain proteoglycan core protein by site-directed mutagenesis
    • Miller, J., Hatch, J. A., Simonis, S., and Cullen, S. E., Identification of the glycosaminoglycan-attachment site of mouse invariant-chain proteoglycan core protein by site-directed mutagenesis, Proc. Natl. Acad. Sci. U.S.A., 85, 1359-1363, 1988.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 1359-1363
    • Miller, J.1    Hatch, J.A.2    Simonis, S.3    Cullen, S.E.4
  • 61
    • 0026584505 scopus 로고
    • Invariant chain: A regulator of antigen presentation
    • Teyton, L. and Peterson, P. A., Invariant chain: a regulator of antigen presentation, Trends In Cell Biol., 2, 52-56, 1992.
    • (1992) Trends in Cell Biol. , vol.2 , pp. 52-56
    • Teyton, L.1    Peterson, P.A.2
  • 62
    • 0024300824 scopus 로고
    • Posttranslational modifications of the Ia-associated invariant protein p41 after gene transfer
    • Koch, N., Posttranslational modifications of the Ia-associated invariant protein p41 after gene transfer, Biochem., 27, 4097-4102, 1988.
    • (1988) Biochem. , vol.27 , pp. 4097-4102
    • Koch, N.1
  • 63
    • 0027498929 scopus 로고
    • Relationship between invariant chain expression and major histocompatibility complex class-II transport into early and late endocytic compartments
    • Romagnoli, P., Layet, C., Yewdell, J., Bakke, O., and Germain, R. N., Relationship between invariant chain expression and major histocompatibility complex class-II transport into early and late endocytic compartments, J. Exp. Med., 177, 583-596, 1993.
    • (1993) J. Exp. Med. , vol.177 , pp. 583-596
    • Romagnoli, P.1    Layet, C.2    Yewdell, J.3    Bakke, O.4    Germain, R.N.5
  • 64
    • 0028226469 scopus 로고
    • Transport properties of free and MHC class II-associated oligomers containing different isoforms of human invariant chain
    • Arunachalam, B., Lamb, C. A., and Cresswell, P., Transport properties of free and MHC class II-associated oligomers containing different isoforms of human invariant chain, Int. Immunol., 6, 439-451, 1993.
    • (1993) Int. Immunol. , vol.6 , pp. 439-451
    • Arunachalam, B.1    Lamb, C.A.2    Cresswell, P.3
  • 65
    • 0026729240 scopus 로고
    • Antigen presentation enhanced by the alternative spliced invariant chain product p41
    • Peterson, M. and Miller, J., Antigen presentation enhanced by the alternative spliced invariant chain product p41, Nature, 357, 596-598, 1992.
    • (1992) Nature , vol.357 , pp. 596-598
    • Peterson, M.1    Miller, J.2
  • 68
    • 0028349810 scopus 로고
    • An N-terminal double arginine motif maintains type II membrane proteins in the endoplasmic reticulum
    • Schultze, M. P., Peterson, P. A., and Jackson, M. R., An N-terminal double arginine motif maintains type II membrane proteins in the endoplasmic reticulum, EMBO J., 13, 1696-1705, 1994.
    • (1994) EMBO J. , vol.13 , pp. 1696-1705
    • Schultze, M.P.1    Peterson, P.A.2    Jackson, M.R.3
  • 69
    • 0024589213 scopus 로고
    • Time course of intracellular associations, processing and cleavages of Ii forms and class II major histocompatibility complex molecules
    • Nguyen, Q. V. and Humphreys, R. E., Time course of intracellular associations, processing and cleavages of Ii forms and class II major histocompatibility complex molecules, J. Biol. Chem., 264, 1631-1637, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 1631-1637
    • Nguyen, Q.V.1    Humphreys, R.E.2
  • 70
    • 0024404855 scopus 로고
    • The role of the Ia-invariant chain complex in the post-translational processing and transport of Ia and invariant chain glycoproteins
    • Simonis, S., Miller, J., and Cullen, S. E., The role of the Ia-invariant chain complex in the post-translational processing and transport of Ia and invariant chain glycoproteins, J. Immunol., 143, 3619-3625, 1989.
    • (1989) J. Immunol. , vol.143 , pp. 3619-3625
    • Simonis, S.1    Miller, J.2    Cullen, S.E.3
  • 71
    • 0025835176 scopus 로고
    • Invariant chain targets HLA class II molecules to acidic endosomes containing internalized influenza virus
    • Lamb, C. A., Yewdell, J. W., Bennink, J. R., and Cresswell, P., Invariant chain targets HLA class II molecules to acidic endosomes containing internalized influenza virus, Proc. Natl. Acad. Sci. U.S.A., 88, 5998-6002, 1991.
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 5998-6002
    • Lamb, C.A.1    Yewdell, J.W.2    Bennink, J.R.3    Cresswell, P.4
  • 72
    • 0028916288 scopus 로고
    • In the absence of major histocompatibility complex class II molecules, invariant chain is translocated to late endocytic compartments by autophagy
    • Chervonsky, A. and Sant, A. J., In the absence of major histocompatibility complex class II molecules, invariant chain is translocated to late endocytic compartments by autophagy, Eur. J. Immunol., 25, 911-918, 1995.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 911-918
    • Chervonsky, A.1    Sant, A.J.2
  • 73
    • 0025202076 scopus 로고
    • MHC class II-associated invariant chain contains a sorting signal for endosomal compartments
    • Bakke, O. and Dobberstein, B., MHC class II-associated invariant chain contains a sorting signal for endosomal compartments, Cell, 63, 707-716, 1990.
    • (1990) Cell , vol.63 , pp. 707-716
    • Bakke, O.1    Dobberstein, B.2
  • 74
    • 0029439973 scopus 로고
    • The function of invariant chain in class II-restricted antigen presentation
    • Ceman, S. and Sant, A., The function of invariant chain in class II-restricted antigen presentation, Sem. in Immunol., 7, 373-387, 1995.
    • (1995) Sem. in Immunol. , vol.7 , pp. 373-387
    • Ceman, S.1    Sant, A.2
  • 75
    • 0026571278 scopus 로고
    • The human class II MHC protein HLA-DR1 assembles as empty a/β heterodimers in the absence of antigenic peptides
    • Stern, L. J. and Wiley, D. C., The human class II MHC protein HLA-DR1 assembles as empty a/β heterodimers in the absence of antigenic peptides, Cell, 68, 465-477, 1992.
    • (1992) Cell , vol.68 , pp. 465-477
    • Stern, L.J.1    Wiley, D.C.2
  • 76
    • 0026742999 scopus 로고
    • HLA-DR associates with specific stress proteins and is retained in the endoplasmic reticulum in invariant chain negative cells
    • Schaiff, W. T., Hruska, K. Jr., McCourt, D. W., Green, M., and Schwartz, B. D., HLA-DR associates with specific stress proteins and is retained in the endoplasmic reticulum in invariant chain negative cells, J. Exp. Med., 176, 657-666, 1992.
    • (1992) J. Exp. Med. , vol.176 , pp. 657-666
    • Schaiff, W.T.1    Hruska Jr., K.2    McCourt, D.W.3    Green, M.4    Schwartz, B.D.5
  • 77
    • 0023018742 scopus 로고
    • Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain
    • Miller, J. and Germain, R. N., Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain, J. Exp. Med., 164, 1478-1489, 1986.
    • (1986) J. Exp. Med. , vol.164 , pp. 1478-1489
    • Miller, J.1    Germain, R.N.2
  • 78
    • 0025820461 scopus 로고
    • Invariant chain influences post-translational processing of HLA-DR molecules
    • Schaiff, W. T., Hruska, K. Jr., Bono, C., Shuman, S., and Schwartz, B. D., Invariant chain influences post-translational processing of HLA-DR molecules, J. Immunol., 147, 603-608, 1991.
    • (1991) J. Immunol. , vol.147 , pp. 603-608
    • Schaiff, W.T.1    Hruska Jr., K.2    Bono, C.3    Shuman, S.4    Schwartz, B.D.5
  • 79
    • 0026589838 scopus 로고
    • Invariant chain can function as a chaperone protein for class II major histocompatibility complex molecules
    • Anderson, M. S. and Miller, J., Invariant chain can function as a chaperone protein for class II major histocompatibility complex molecules, Proc. Natl. Acad. Sci. U.S.A., 89, 2282-2286, 1992.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 2282-2286
    • Anderson, M.S.1    Miller, J.2
  • 80
    • 0025249197 scopus 로고
    • The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route
    • Neefjes, J. J., Stollorz, V., Peters, P. J., Geuze, H. J., and Ploegh, H. L., The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route, Cell, 61, 171-183, 1990.
    • (1990) Cell , vol.61 , pp. 171-183
    • Neefjes, J.J.1    Stollorz, V.2    Peters, P.J.3    Geuze, H.J.4    Ploegh, H.L.5
  • 81
    • 0025939316 scopus 로고
    • Processed antigen binds to newly synthesized MHC class II molecules in antigen-specific B lymphocytes
    • Davidson, H. W., Reid, P. A., Lanzavecchia, A., and Watts, C., Processed antigen binds to newly synthesized MHC class II molecules in antigen-specific B lymphocytes, Cell, 67, 105-116, 1991.
    • (1991) Cell , vol.67 , pp. 105-116
    • Davidson, H.W.1    Reid, P.A.2    Lanzavecchia, A.3    Watts, C.4
  • 83
    • 0026708305 scopus 로고
    • Stable surface expression of invariant chain prevents peptide presentation by HLA-DR
    • Roche,P. A., Teletski, C. L., Karp, D. R., Pinet, V., Bakke, O., and Long, E, O., Stable surface expression of invariant chain prevents peptide presentation by HLA-DR, EMBO J., 11, 2841-2847, 1992.
    • (1992) EMBO J. , vol.11 , pp. 2841-2847
    • Rochep, A.1    Teletski, C.L.2    Karp, D.R.3    Pinet, V.4    Bakke, O.5    Long, E.O.6
  • 84
    • 0027202548 scopus 로고
    • Intracellular distribution of the MHC class II molecules and the associated invariant chain (Ii) in different cell lines
    • Simonsen, A., Momburg, F., Drexler, J., Hämmerling, G. J., and Bakke, O., Intracellular distribution of the MHC class II molecules and the associated invariant chain (Ii) in different cell lines, Int. Immunol., 5, 903-917, 1993.
    • (1993) Int. Immunol. , vol.5 , pp. 903-917
    • Simonsen, A.1    Momburg, F.2    Drexler, J.3    Hämmerling, G.J.4    Bakke, O.5
  • 85
    • 0028229612 scopus 로고
    • An LI and ML motif in the cytoplasmic tail of the MHC-associated invariant chain mediate rapid internalization
    • Bremnes, B., Madsen, T., Gedde-Dahl, M., and Bakke, O., An LI and ML motif in the cytoplasmic tail of the MHC-associated invariant chain mediate rapid internalization, J. Cell Sci, 107, 2021-2032, 1994.
    • (1994) J. Cell Sci , vol.107 , pp. 2021-2032
    • Bremnes, B.1    Madsen, T.2    Gedde-Dahl, M.3    Bakke, O.4
  • 86
    • 0028282982 scopus 로고
    • Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment
    • Odorizzi, C. G., Trowbridge, I. S., Xue, L., Hopkins, C. R., Davis, C. D., and Collawn, J. F., Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment, J. Cell Biol., 126, 317-330, 1994.
    • (1994) J. Cell Biol. , vol.126 , pp. 317-330
    • Odorizzi, C.G.1    Trowbridge, I.S.2    Xue, L.3    Hopkins, C.R.4    Davis, C.D.5    Collawn, J.F.6
  • 88
    • 0029155721 scopus 로고
    • Invariant chain-independent antigen presentation depends primarily upon the pool of newly synthesized MHC class II molecules
    • Swier, K. and Miller, J., Invariant chain-independent antigen presentation depends primarily upon the pool of newly synthesized MHC class II molecules, J. Immunol., 155, 1851-1861, 1995.
    • (1995) J. Immunol. , vol.155 , pp. 1851-1861
    • Swier, K.1    Miller, J.2
  • 90
    • 0025947902 scopus 로고
    • Rapid intracellular pathway gives rise to cell surface expression of the MHC class II-associated invariant chain (CD74)
    • Koch, N., Moldenhauer, G., Hofmann, W. J., and Moller, P., Rapid intracellular pathway gives rise to cell surface expression of the MHC class II-associated invariant chain (CD74), J. Immunol., 147, 2643-2651, 1991.
    • (1991) J. Immunol. , vol.147 , pp. 2643-2651
    • Koch, N.1    Moldenhauer, G.2    Hofmann, W.J.3    Moller, P.4
  • 91
    • 0027258589 scopus 로고
    • Cell-surface expression of human histocompatibility leukocyte antigen (HLA) class II-associated invariant chain (CD74) does not always correlate with cell-surface expression of HLA class II molecules
    • Wilson, K. M., Labeta, M. O., Pawelec, G., and Fernandez, N., Cell-surface expression of human histocompatibility leukocyte antigen (HLA) class II-associated invariant chain (CD74) does not always correlate with cell-surface expression of HLA class II molecules, Immunol., 79, 331-335, 1993.
    • (1993) Immunol. , vol.79 , pp. 331-335
    • Wilson, K.M.1    Labeta, M.O.2    Pawelec, G.3    Fernandez, N.4
  • 92
    • 0028967148 scopus 로고
    • Surface expression of the invariant chain (CD74) is independent of concomitant expression of major histocompatibility complex class II antigens
    • Henne, C., Schwenk, F., Koch, N., and Moller, P., Surface expression of the invariant chain (CD74) is independent of concomitant expression of major histocompatibility complex class II antigens, Immunology; 84, 177-182, 1995.
    • (1995) Immunology , vol.84 , pp. 177-182
    • Henne, C.1    Schwenk, F.2    Koch, N.3    Moller, P.4
  • 93
    • 0027326548 scopus 로고
    • Cell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalization
    • Roche, P. A., Teletski, C. L., Stang, E., Bakke, O., and Long, E. O., Cell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalization, Proc. Natl. Acad. Sci. U.S.A., 90, 8581-8585, 1993.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 8581-8585
    • Roche, P.A.1    Teletski, C.L.2    Stang, E.3    Bakke, O.4    Long, E.O.5
  • 94
    • 0028626201 scopus 로고
    • Endosomal localization of MHC class II-invariant chain complexes
    • Miller, J., Endosomal localization of MHC class II-invariant chain complexes, Immunol. Res., 13, 244-252, 1994.
    • (1994) Immunol. Res. , vol.13 , pp. 244-252
    • Miller, J.1
  • 95
    • 0025038910 scopus 로고
    • Mouse B lymphocyte specific endocytosis and recycling of MHC class II molecules
    • Salamero, J., Humbert, M., Cosson, P., and Davoust, J., Mouse B lymphocyte specific endocytosis and recycling of MHC class II molecules, EMBO J., 9, 3489-3494, 1990.
    • (1990) EMBO J. , vol.9 , pp. 3489-3494
    • Salamero, J.1    Humbert, M.2    Cosson, P.3    Davoust, J.4
  • 96
    • 0028275138 scopus 로고
    • A segment of MHC class II β chain plays a critical role in targeting class II molecules to the endocytic pathway
    • Chervonsky, A. V., Gordon, L., and Sant. A., A segment of MHC class II β chain plays a critical role in targeting class II molecules to the endocytic pathway, Int. Immunol., 6, 973-982, 1994.
    • (1994) Int. Immunol. , vol.6 , pp. 973-982
    • Chervonsky, A.V.1    Gordon, L.2    Sant, A.3
  • 97
    • 0642282644 scopus 로고
    • Intracellular class II HLA antigens are accessible to transferrin-neuraminidase conjugates internalized by receptor-mediated endocytosis
    • Cresswell, P., Intracellular class II HLA antigens are accessible to transferrin-neuraminidase conjugates internalized by receptor-mediated endocytosis, Proc. Natl. Acad. Sci U.S.A., 82, 8188-8192, 1985.
    • (1985) Proc. Natl. Acad. Sci U.S.A. , vol.82 , pp. 8188-8192
    • Cresswell, P.1
  • 98
    • 0025014816 scopus 로고
    • Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment
    • Guagliardi, L. E., Koppelman, B., Blum, J. S., Marks, M. S., Cresswell, P., and Brodsky, F. M., Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment, Nature, 343, 133-139, 1990.
    • (1990) Nature , vol.343 , pp. 133-139
    • Guagliardi, L.E.1    Koppelman, B.2    Blum, J.S.3    Marks, M.S.4    Cresswell, P.5    Brodsky, F.M.6
  • 99
    • 0028922618 scopus 로고
    • Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles
    • Amigorena, S., Webster, P., Drake, J., Newcomb, J., Cresswell, P., and Mellman, I., Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles, J. Exp. Med., 181, 1729-1741, 1995.
    • (1995) J. Exp. Med. , vol.181 , pp. 1729-1741
    • Amigorena, S.1    Webster, P.2    Drake, J.3    Newcomb, J.4    Cresswell, P.5    Mellman, I.6
  • 100
    • 0028970286 scopus 로고
    • Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptideloaded class II in multiple compartments
    • Castellino, F. and Germain, R. N., Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptideloaded class II in multiple compartments, Immunity, 2, 73-88, 1995.
    • (1995) Immunity , vol.2 , pp. 73-88
    • Castellino, F.1    Germain, R.N.2
  • 101
    • 0028861481 scopus 로고
    • Invariant chain induces a delayed transport from early to late endosomes
    • Gorvel, J. P., Escola, J. M., Stang, E., and Bakke, O., Invariant chain induces a delayed transport from early to late endosomes, J. Biol. Chem., 270, 2741-2746, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2741-2746
    • Gorvel, J.P.1    Escola, J.M.2    Stang, E.3    Bakke, O.4
  • 102
    • 0026034448 scopus 로고
    • Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments
    • Peters, P. J., Neefjes, J. J., Oorschot, V., Ploegh, H. L., and Geuze, H. J., Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments, Nature, 349, 669-676, 1991.
    • (1991) Nature , vol.349 , pp. 669-676
    • Peters, P.J.1    Neefjes, J.J.2    Oorschot, V.3    Ploegh, H.L.4    Geuze, H.J.5
  • 103
    • 0029076285 scopus 로고
    • Intracellular transport of invariant chain MHC class II complexes to the peptide-loading compartment
    • Xu, X. X., Song, W. X., Cho, H., Qiu, Y., and Pierce, S. K., Intracellular transport of invariant chain MHC class II complexes to the peptide-loading compartment, J. Immunol., 155, 2984-2992, 1995.
    • (1995) J. Immunol. , vol.155 , pp. 2984-2992
    • Xu, X.X.1    Song, W.X.2    Cho, H.3    Qiu, Y.4    Pierce, S.K.5
  • 104
    • 0028229009 scopus 로고
    • Isolation and characterization of the intracellular MHC class II compartment
    • Tulp, A., Verwoerd, D., Dobberstein, B., Ploegh, H. L., and Pieters, J., Isolation and characterization of the intracellular MHC class II compartment, Nature, 369, 120-126, 1994.
    • (1994) Nature , vol.369 , pp. 120-126
    • Tulp, A.1    Verwoerd, D.2    Dobberstein, B.3    Ploegh, H.L.4    Pieters, J.5
  • 105
    • 0028303848 scopus 로고
    • Antigen processing and class II MHC peptide loading compartments in human B-lymphoblastoid cells
    • West, M. A., Lucocq, J. M., and Watts, C., Antigen processing and class II MHC peptide loading compartments in human B-lymphoblastoid cells, Nature, 369, 147-150, 1994.
    • (1994) Nature , vol.369 , pp. 147-150
    • West, M.A.1    Lucocq, J.M.2    Watts, C.3
  • 107
    • 0028285075 scopus 로고
    • Separation of subcellular compartments containing distinct functional forms of MHC class II
    • Qiu, Y., Xu, X., Wandinger-Ness, A., Dalke, D. P., and Pierce, S. K., Separation of subcellular compartments containing distinct functional forms of MHC class II, J. Cell Biol., 125, 595-605, 1994.
    • (1994) J. Cell Biol. , vol.125 , pp. 595-605
    • Qiu, Y.1    Xu, X.2    Wandinger-Ness, A.3    Dalke, D.P.4    Pierce, S.K.5
  • 109
    • 0028618339 scopus 로고
    • Reconstitution of an operational MHC class II compartment in nonantigen-presenting cells
    • Karlsson, L., Péléraux, A., Lindstedt, R., Liljedahl, M., and Peterson, P. A., Reconstitution of an operational MHC class II compartment in nonantigen-presenting cells, Science, 266, 1569-1573, 1994.
    • (1994) Science , vol.266 , pp. 1569-1573
    • Karlsson, L.1    Péléraux, A.2    Lindstedt, R.3    Liljedahl, M.4    Peterson, P.A.5
  • 110
    • 0028362563 scopus 로고
    • Transport and intracellular distribution of MHC class II molecules and associated invariant chain in normal and antigen-processing mutant cell lines
    • Riberdy, J. M., Avva, R. R., Geuze, H. J., and Cresswell, P., Transport and intracellular distribution of MHC class II molecules and associated invariant chain in normal and antigen-processing mutant cell lines, J. Cell Biol., 125, 1225-1237, 1994.
    • (1994) J. Cell Biol. , vol.125 , pp. 1225-1237
    • Riberdy, J.M.1    Avva, R.R.2    Geuze, H.J.3    Cresswell, P.4
  • 111
    • 0027370367 scopus 로고
    • Immunogenic peptides bind to class II MHC molecules in an early lysosomal compartment
    • Harding, C. V. and Geuze, H. J., Immunogenic peptides bind to class II MHC molecules in an early lysosomal compartment, J. Immunol., 151, 3988-3998, 1993.
    • (1993) J. Immunol. , vol.151 , pp. 3988-3998
    • Harding, C.V.1    Geuze, H.J.2
  • 112
    • 0026583941 scopus 로고
    • Inhibition of endosomal proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistant αβ heterodimers
    • Neefjes, J. J. and Ploegh, H. L., Inhibition of endosomal proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistant αβ heterodimers, EMBO J., 11, 411-416, 1992.
    • (1992) EMBO J. , vol.11 , pp. 411-416
    • Neefjes, J.J.1    Ploegh, H.L.2
  • 113
    • 0027232592 scopus 로고
    • Invariant chain retains MHC class II molecules in the endocytic pathway
    • Loss, G. E. and Sant, A. J., Invariant chain retains MHC class II molecules in the endocytic pathway, J. Immunol., 150, 3187-3197, 1993.
    • (1993) J. Immunol. , vol.150 , pp. 3187-3197
    • Loss, G.E.1    Sant, A.J.2
  • 114
    • 0028344898 scopus 로고
    • Endosomal aspartic proteinases are required for invariant-chain processing
    • Maric, M. A., Taylor, M. D., and Blum, J. S., Endosomal aspartic proteinases are required for invariant-chain processing, Proc. Natl. Acad. Sci. U.S.A., 91, 2171-2175, 1994.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 2171-2175
    • Maric, M.A.1    Taylor, M.D.2    Blum, J.S.3
  • 115
    • 0028853165 scopus 로고
    • Delivery of nascent MHC class II-invariant chain complexes to lysosomal compartments and proteolysis of invariant chain by cysteine proteases precedes peptide binding in B-lymphoblastoid cells
    • Morton, P. A., Zacheis, M. L., Giacoletto, K. S., Manning, J. A., and Schwartz, B. D., Delivery of nascent MHC class II-invariant chain complexes to lysosomal compartments and proteolysis of invariant chain by cysteine proteases precedes peptide binding in B-lymphoblastoid cells, J. Immunol., 154, 137-150, 1995.
    • (1995) J. Immunol. , vol.154 , pp. 137-150
    • Morton, P.A.1    Zacheis, M.L.2    Giacoletto, K.S.3    Manning, J.A.4    Schwartz, B.D.5
  • 116
    • 0028572551 scopus 로고
    • Both cathepsin B and cathepsin D are necessary for processing of ovalbumin as well as for degradation of class IIMHC invariant chain
    • Mizuochi, T., Yee, S. T., Kasai, M., Kakiuchi, T., Muno, D., and Kominami, E., Both cathepsin B and cathepsin D are necessary for processing of ovalbumin as well as for degradation of class IIMHC invariant chain, Immunol. Lett., 43, 189-193, 1994.
    • (1994) Immunol. Lett. , vol.43 , pp. 189-193
    • Mizuochi, T.1    Yee, S.T.2    Kasai, M.3    Kakiuchi, T.4    Muno, D.5    Kominami, E.6
  • 117
    • 0025824732 scopus 로고
    • Intracellular transport and localization of Major Histocompatibility Complex class II molecules and associated invariant chain
    • Pieters, J., Horstmann, H., Bakke, O., Griffiths, G., and Lipp, J., Intracellular transport and localization of Major Histocompatibility Complex class II molecules and associated invariant chain, J. Cell Biol., 115, 1213-1223, 1991.
    • (1991) J. Cell Biol. , vol.115 , pp. 1213-1223
    • Pieters, J.1    Horstmann, H.2    Bakke, O.3    Griffiths, G.4    Lipp, J.5
  • 118
    • 0011720253 scopus 로고
    • Role for intracellular proteases in the processing and transport of class II HLA antigens
    • Blum, J. S. and Cresswell, P., Role for intracellular proteases in the processing and transport of class II HLA antigens, Proc. Natl. Acad. Sci. U.S.A., 85, 3975-3979, 1988.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 3975-3979
    • Blum, J.S.1    Cresswell, P.2
  • 119
    • 0024565825 scopus 로고
    • Inhibition by leupeptine and antipaine of intracellular proteolysis of Ii
    • Nguyen, Q. V., Knapp, W., and Humphreys, R. E., Inhibition by leupeptine and antipaine of intracellular proteolysis of Ii, Hum. Immunol., 24, 153-163, 1989.
    • (1989) Hum. Immunol. , vol.24 , pp. 153-163
    • Nguyen, Q.V.1    Knapp, W.2    Humphreys, R.E.3
  • 120
    • 0027094238 scopus 로고
    • A block in degradation of MHC class II-associated invariant chain correlates with a reduction in transport from endosome carrier vesicles to the prelysosome compartment
    • Zachgo, S., Dobberstein, B., and Griffiths, G., A block in degradation of MHC class II-associated invariant chain correlates with a reduction in transport from endosome carrier vesicles to the prelysosome compartment, J. Cell Sci., 103, 811-822, 1992.
    • (1992) J. Cell Sci. , vol.103 , pp. 811-822
    • Zachgo, S.1    Dobberstein, B.2    Griffiths, G.3
  • 121
    • 0025760601 scopus 로고
    • Cathepsin B cleavage of Ii from class II MHC α- and β-chains
    • Reyes, V. E., Lu, S., and Humphreys, R. E., Cathepsin B cleavage of Ii from class II MHC α- and β-chains, J. Immunol., 146, 3877-3880, 1991.
    • (1991) J. Immunol , vol.146 , pp. 3877-3880
    • Reyes, V.E.1    Lu, S.2    Humphreys, R.E.3
  • 122
    • 0026101418 scopus 로고
    • Characterization of fragments of the murine la-associated invariant chain
    • Mehringer, J. H., Harris, M. R., Kindle, C. S., McCourt, D. W., and Cullen, S. E., Characterization of fragments of the murine la-associated invariant chain, J. Immunol., 146, 920-927, 1991.
    • (1991) J. Immunol. , vol.146 , pp. 920-927
    • Mehringer, J.H.1    Harris, M.R.2    Kindle, C.S.3    McCourt, D.W.4    Cullen, S.E.5
  • 124
    • 0028877058 scopus 로고
    • T cell recognition of major histocompatibility complex class II complexes with invariant chain processing intermediates
    • Morkowski, S., Goldrath, A. W., Eastman, S., Ramachandra, L., Freed, D. C., Whiteley, P., and Rudensky, A. Y., T cell recognition of major histocompatibility complex class II complexes with invariant chain processing intermediates, J. Exp. Med., 182, 1403-1413, 1995.
    • (1995) J. Exp. Med. , vol.182 , pp. 1403-1413
    • Morkowski, S.1    Goldrath, A.W.2    Eastman, S.3    Ramachandra, L.4    Freed, D.C.5    Whiteley, P.6    Rudensky, A.Y.7
  • 125
    • 0026440236 scopus 로고
    • HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides
    • Riberdy, J. M., Newcomb, J. R., Surman, M. J., Barbosa, J. A., and Cresswell, P., HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides, Nature, 360, 414-477, 1992.
    • (1992) Nature , vol.360 , pp. 414-477
    • Riberdy, J.M.1    Newcomb, J.R.2    Surman, M.J.3    Barbosa, J.A.4    Cresswell, P.5
  • 127
    • 0026733449 scopus 로고
    • Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size
    • Chicz, R. M., Urban, R. G., Lane, W. S., Gorga, J. C., Stern, L. J., Vignali, D. A. A., and Strominger, J. L., Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size, Nature, 358, 764-768, 1992.
    • (1992) Nature , vol.358 , pp. 764-768
    • Chicz, R.M.1    Urban, R.G.2    Lane, W.S.3    Gorga, J.C.4    Stern, L.J.5    Vignali, D.A.A.6    Strominger, J.L.7
  • 128
    • 0028945021 scopus 로고
    • Supermotifs enable natural invariant chain-derived peptides to interact with many major histocompatibility complex-class II molecules
    • Malcherek, G., Gnau, V., Jung, G., Rammensee, H. G., and Melms, A., Supermotifs enable natural invariant chain-derived peptides to interact with many major histocompatibility complex-class II molecules, J. Exp. Med., 181, 527-536, 1995.
    • (1995) J. Exp. Med. , vol.181 , pp. 527-536
    • Malcherek, G.1    Gnau, V.2    Jung, G.3    Rammensee, H.G.4    Melms, A.5
  • 129
    • 0029131499 scopus 로고
    • Kinetics of the reactions between the invariant chain (85-99) peptide and proteins of the munne class II MHC
    • Liang, M. N., Beeson, C., Mason, K., and McConnell, H. M., Kinetics of the reactions between the invariant chain (85-99) peptide and proteins of the munne class II MHC. Int. Immunol., 7, 1397-1404, 1995.
    • (1995) Int. Immunol. , vol.7 , pp. 1397-1404
    • Liang, M.N.1    Beeson, C.2    Mason, K.3    McConnell, H.M.4
  • 131
    • 0028676010 scopus 로고
    • In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides
    • Avva, R. R. and Cresswell, P., In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides, Immunity, 1, 763-774, 1994.
    • (1994) Immunity , vol.1 , pp. 763-774
    • Avva, R.R.1    Cresswell, P.2
  • 132
    • 0028898253 scopus 로고
    • Allelic differences affecting invariant chain dependency of MHC class II subunit assembly
    • Bikoff, E. K., Germain, R. N., and Robertson, E. J., Allelic differences affecting invariant chain dependency of MHC class II subunit assembly, Immunity, 2, 301-310, 1995.
    • (1995) Immunity , vol.2 , pp. 301-310
    • Bikoff, E.K.1    Germain, R.N.2    Robertson, E.J.3
  • 133
    • 0028921633 scopus 로고
    • Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II
    • Sette, A., Southwood, S., Miller, J., and Appella, E., Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II, J. Exp. Med., 181, 677-683, 1995.
    • (1995) J. Exp. Med. , vol.181 , pp. 677-683
    • Sette, A.1    Southwood, S.2    Miller, J.3    Appella, E.4
  • 134
    • 0029014498 scopus 로고
    • Invariant chain peptides enhancing or inhibiting the presentation of antigenic peptides by major histocompatibility complex class II molecules
    • Adams, S. and Humphreys, R. E., Invariant chain peptides enhancing or inhibiting the presentation of antigenic peptides by major histocompatibility complex class II molecules, Eur. J. Immunol., 25, 1693-1702, 1995.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1693-1702
    • Adams, S.1    Humphreys, R.E.2
  • 135
    • 0028800411 scopus 로고
    • Clip binds to HLA class II using methionine-based, allele-dependent motifs as well as allele-independent supermotifs
    • Geluk, A., Van Meijgaarden, K. E., Drijfhout, J. W., and Ottenhoff, T., Clip binds to HLA class II using methionine-based, allele-dependent motifs as well as allele-independent supermotifs, Mol. Immunol., 32, 975-981, 1995.
    • (1995) Mol. Immunol. , vol.32 , pp. 975-981
    • Geluk, A.1    Van Meijgaarden, K.E.2    Drijfhout, J.W.3    Ottenhoff, T.4
  • 136
    • 0029114962 scopus 로고
    • Structural features of the invariant chain fragment CLIP controlling rapid release from HLA-DR molecules and inhibition of peptide binding
    • Kropshofer, H., Vogt, A. B., and Hämmerling, G. J., Structural features of the invariant chain fragment CLIP controlling rapid release from HLA-DR molecules and inhibition of peptide binding, Proc. Natl. Acad. Sci. U.S.A., 92, 8313-8317, 1995.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 8313-8317
    • Kropshofer, H.1    Vogt, A.B.2    Hämmerlingg, J.3
  • 137
    • 0028942082 scopus 로고
    • Binding of an invariant-chain peptide, CLIP, to I-A major histocompatibility complex class II molecules
    • Gautam, A. M., Pearson, C., Quinn, V., McDevitt, H. O., and Milburn, P. J., Binding of an invariant-chain peptide, CLIP, to I-A major histocompatibility complex class II molecules, Proc. Natl. Acad. Sci. U.S.A., 92, 335-339, 1995.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 335-339
    • Gautam, A.M.1    Pearson, C.2    Quinn, V.3    McDevitt, H.O.4    Milburn, P.J.5
  • 138
    • 0028823585 scopus 로고
    • The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3
    • Ghosh, P., Amaya, M., Mellins, E., and Wiley, D. C., The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3, Nature, 378, 457-462, 1995.
    • (1995) Nature , vol.378 , pp. 457-462
    • Ghosh, P.1    Amaya, M.2    Mellins, E.3    Wiley, D.C.4
  • 139
    • 0025313181 scopus 로고
    • Regulation of antigen presentation by acidic pH
    • Jensen, P., Regulation of antigen presentation by acidic pH, J. Exp. Med., 171, 1779-1784, 1990.
    • (1990) J. Exp. Med. , vol.171 , pp. 1779-1784
    • Jensen, P.1
  • 140
    • 0025898515 scopus 로고
    • Expression of a class II major histocompatibility complex (MHC) heterodimer in a lipid-linked form with enhanced peptide/soluble MHC complex formation at low pH
    • Wettstein, D. A., Boniface, J. J., Reay, P. A., Schild, H., and Davis, M., Expression of a class II major histocompatibility complex (MHC) heterodimer in a lipid-linked form with enhanced peptide/soluble MHC complex formation at low pH, J. Exp. Med., 174, 219-228, 1991.
    • (1991) J. Exp. Med. , vol.174 , pp. 219-228
    • Wettstein, D.A.1    Boniface, J.J.2    Reay, P.A.3    Schild, H.4    Davis, M.5
  • 141
    • 0026643116 scopus 로고
    • pH dependence and exchange of high and low responder peptides binding to a class II MHC molecule
    • Reay, P. A., Wettstein, D. A., and Davis, M. M., pH dependence and exchange of high and low responder peptides binding to a class II MHC molecule, EMBO J., 11, 2829-2839, 1992.
    • (1992) EMBO J. , vol.11 , pp. 2829-2839
    • Reay, P.A.1    Wettstein, D.A.2    Davis, M.M.3
  • 142
    • 0026595058 scopus 로고
    • pH dependence for an acidic intracellular compartment being the organelle of interac-tion
    • Mouritsen, S., Stryhn Hansen, A., Laub Petersen, T., and Buus, S., pH dependence for an acidic intracellular compartment being the organelle of interac-tion, J. Immunol., 148, 1438-1444, 1992.
    • (1992) J. Immunol. , vol.148 , pp. 1438-1444
    • Mouritsen, S.1    Stryhn Hansen, A.2    Laub Petersen, T.3    Buus, S.4
  • 146
    • 0028981178 scopus 로고
    • HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading
    • Denzin, L. K. and Cresswell, P., HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading, Cell, 82, 155-165, 1995.
    • (1995) Cell , vol.82 , pp. 155-165
    • Denzin, L.K.1    Cresswell, P.2
  • 147
    • 0029084023 scopus 로고
    • DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide
    • Sherman, M. A., Weber, D. A., and Jensen, P. E., DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide, Immunity, 3, 197-205, 1995.
    • (1995) Immunity , vol.3 , pp. 197-205
    • Sherman, M.A.1    Weber, D.A.2    Jensen, P.E.3
  • 150
    • 0025826118 scopus 로고
    • MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding
    • Germain, R. N. and Hendrix, L. R., MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding, Nature, 353, 134-139, 1991.
    • (1991) Nature , vol.353 , pp. 134-139
    • Germain, R.N.1    Hendrix, L.R.2
  • 151
    • 0025266452 scopus 로고
    • Invariant chain influences the immunological recognition of MHC class II molecules
    • Peterson, M. and Miller, J., Invariant chain influences the immunological recognition of MHC class II molecules, Nature, 345, 172-174, 1990.
    • (1990) Nature , vol.345 , pp. 172-174
    • Peterson, M.1    Miller, J.2
  • 152
    • 0026718083 scopus 로고
    • T and B cell receptors discriminate major histocompatibility complex class II conformations influenced by the invariant chain
    • Rath, S., Lin, R. H., Rudensky, A., and Janeway, C. Jr., T and B cell receptors discriminate major histocompatibility complex class II conformations influenced by the invariant chain, Eur. J. Immunol., 22, 2121-2127, 1992.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2121-2127
    • Rath, S.1    Lin, R.H.2    Rudensky, A.3    Janeway Jr., C.4
  • 153
    • 0028857202 scopus 로고
    • Acquisition of peptides by MHC class II polypeptides in the absence of the invariant chain
    • Hitzel, C., Van Endert, P., and Koch, N., Acquisition of peptides by MHC class II polypeptides in the absence of the invariant chain, J. Immunol., 154, 1048-1056, 1995.
    • (1995) J. Immunol. , vol.154 , pp. 1048-1056
    • Hitzel, C.1    Van Endert, P.2    Koch, N.3
  • 154
    • 0021968677 scopus 로고
    • Binding of immunogenic peptides to Ia histocompatibility molecules
    • Babbitt, B. P., Allen, P. M., Matsueda, G. R., Haber, E., and Unanue, E. R., Binding of immunogenic peptides to Ia histocompatibility molecules, Nature, 317, 359-361, 1985.
    • (1985) Nature , vol.317 , pp. 359-361
    • Babbitt, B.P.1    Allen, P.M.2    Matsueda, G.R.3    Haber, E.4    Unanue, E.R.5
  • 155
    • 0022636572 scopus 로고
    • A group-specific inhibitor of lysosomal cysteine proteinases selectively inhibits both proteolytic degradation and presentation of the antigen dinitrophenyl-poly-L-Lysine by guinea pig accessory cells to T cells
    • Buus, S. and Wederlin, O., A group-specific inhibitor of lysosomal cysteine proteinases selectively inhibits both proteolytic degradation and presentation of the antigen dinitrophenyl-poly-L-Lysine by guinea pig accessory cells to T cells, J. Immunol., 136, 452-460, 1986.
    • (1986) J. Immunol. , vol.136 , pp. 452-460
    • Buus, S.1    Wederlin, O.2
  • 156
    • 0025331726 scopus 로고
    • Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding
    • Roche, P. A. and Cresswell, P., Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding. Nature, 345, 615-618, 1990.
    • (1990) Nature , vol.345 , pp. 615-618
    • Roche, P.A.1    Cresswell, P.2
  • 157
    • 0026353496 scopus 로고
    • Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules
    • Roche, P. A. and Cresswell, P., Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules, Proc. Natl. Acad. Sci. U.S.A., 88, 3150-3154, 1991.
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 3150-3154
    • Roche, P.A.1    Cresswell, P.2
  • 158
    • 0028341362 scopus 로고
    • Assembly of HLA DR1 molecules translated in vitro: Binding of peptide in the endoplasmic reticulum precludes association with invariant chain
    • Bijlmakers, M. J., Benaroch, P., and Ploegh, H. L., Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain, EMBO J., 13, 2699-2707, 1994.
    • (1994) EMBO J. , vol.13 , pp. 2699-2707
    • Bijlmakers, M.J.1    Benaroch, P.2    Ploegh, H.L.3
  • 159
    • 0028919184 scopus 로고
    • Poor loading of major histocompatibility complex class II molecules with endogeneously synthesized short peptides in the absence of invariant chain
    • Busch, R., Vturina, I. Y., Drexler, J., Momburg, F., and Hämmerling, G. J., Poor loading of major histocompatibility complex class II molecules with endogeneously synthesized short peptides in the absence of invariant chain, Eur. J. Immunol., 25, 48-53, 1995.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 48-53
    • Busch, R.1    Vturina, I.Y.2    Drexler, J.3    Momburg, F.4    Hämmerling, G.J.5
  • 160
    • 0027950862 scopus 로고
    • Mutually exclusive binding of peptide and invariant chain to major histocompatibility complex class II antigens
    • Ericson, M. L., Sundstrom, M., Sansom, D. M., and Charron, D. J., Mutually exclusive binding of peptide and invariant chain to major histocompatibility complex class II antigens, J. Biol. Chem., 269, 26531-26538, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 26531-26538
    • Ericson, M.L.1    Sundstrom, M.2    Sansom, D.M.3    Charron, D.J.4
  • 161
    • 0027272815 scopus 로고
    • DR alpha-beta-dimers released from complexes with invariant chain fail to stimulate alloreactive T cell clones
    • Demotz, S., DR alpha-beta-dimers released from complexes with invariant chain fail to stimulate alloreactive T cell clones, Eur. J. Immunol., 23, 2100-2108, 1993.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2100-2108
    • Demotz, S.1
  • 163
    • 0027373035 scopus 로고
    • Studies on naturally processed peptides associated with MHC class II molecules
    • Rudensky, A. and Janeway, C. Jr., Studies on naturally processed peptides associated with MHC class II molecules, Chem. Immunol., 57, 134-151, 1993.
    • (1993) Chem. Immunol. , vol.57 , pp. 134-151
    • Rudensky, A.1    Janeway Jr., C.2
  • 165
    • 0026031205 scopus 로고
    • MHC Class II-restricted presentation of intracellular antigen
    • Weiss, S. and Bogen, B., MHC Class II-restricted presentation of intracellular antigen, Cell, 64, 767-776, 1991.
    • (1991) Cell , vol.64 , pp. 767-776
    • Weiss, S.1    Bogen, B.2
  • 166
    • 0024550907 scopus 로고
    • HLA class II-restricted presentation of cytoplasmic measles virus antigens to cytotoxic T cells
    • Jacobson, S., Sekaly, R., Jacobson, C. L., McFarland, H. F., and Long, E. O., HLA class II-restricted presentation of cytoplasmic measles virus antigens to cytotoxic T cells, J. Virol., 63, 1756-1762, 1989.
    • (1989) J. Virol. , vol.63 , pp. 1756-1762
    • Jacobson, S.1    Sekaly, R.2    Jacobson, C.L.3    McFarland, H.F.4    Long, E.O.5
  • 167
    • 0025159204 scopus 로고
    • Class-II MHC molecules can use the endogenous pathway of antigen presentation
    • Nuchtern, J. G., Biddison, W. E., and Klausner, R. D., Class-II MHC molecules can use the endogenous pathway of antigen presentation, Nature, 343, 74-76, 1990.
    • (1990) Nature , vol.343 , pp. 74-76
    • Nuchtern, J.G.1    Biddison, W.E.2    Klausner, R.D.3
  • 168
    • 0025035510 scopus 로고
    • An endogenous processing pathway in vaccinia virusinfected cells for presentation of cytoplasmic antigens to class II-restricted T cells
    • Jaraquemada, D., Marti, M., and Long, E., An endogenous processing pathway in vaccinia virusinfected cells for presentation of cytoplasmic antigens to class II-restricted T cells, J. Exp. Med., 172, 947-952, 1990.
    • (1990) J. Exp. Med. , vol.172 , pp. 947-952
    • Jaraquemada, D.1    Marti, M.2    Long, E.3
  • 169
    • 0025860160 scopus 로고
    • Class II-restricted IgG2ab-specific T cells recognize a signal-minus form of the V-Ch3b antigen
    • Bikoff, E., Class II-restricted IgG2ab-specific T cells recognize a signal-minus form of the V-Ch3b antigen, Eur. J. Immunol., 21, 1411-1417, 1991.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 1411-1417
    • Bikoff, E.1
  • 171
    • 0027138095 scopus 로고
    • Presentation of cytosolic antigen by HLA-DR requires a function encoded in the class-II region of the MHC
    • Malnati, M. S., Ceman, S., Weston, M., Demars, R., and Long, E. O., Presentation of cytosolic antigen by HLA-DR requires a function encoded in the class-II region of the MHC, J. Immunol., 151, 6751-6756, 1993.
    • (1993) J. Immunol. , vol.151 , pp. 6751-6756
    • Malnati, M.S.1    Ceman, S.2    Weston, M.3    Demars, R.4    Long, E.O.5
  • 172
    • 0027232740 scopus 로고
    • Invariant chain expression similarly controls presentation of endogenously synthesized and exogenous antigens by MHC class II molecules
    • Lombard-Platet, S., Bertolino, P., Gimenez, C., Humbert, M., Gerlier, D., and Rabourdin-Combe, C., Invariant chain expression similarly controls presentation of endogenously synthesized and exogenous antigens by MHC class II molecules, Cell Immunol., 148, 60-70, 1993.
    • (1993) Cell Immunol. , vol.148 , pp. 60-70
    • Lombard-Platet, S.1    Bertolino, P.2    Gimenez, C.3    Humbert, M.4    Gerlier, D.5    Rabourdin-Combe, C.6
  • 173
    • 0027977846 scopus 로고
    • Invariant chain prevents the HLA-DR-restricted presentation of a cytosolic peptide
    • Long, E. O., LaVaute, T., Pinet, V., and Jaraquemada, D., Invariant chain prevents the HLA-DR-restricted presentation of a cytosolic peptide, J. Immunol., 153, 1487-1494, 1994.
    • (1994) J. Immunol. , vol.153 , pp. 1487-1494
    • Long, E.O.1    LaVaute, T.2    Pinet, V.3    Jaraquemada, D.4
  • 174
    • 0028354968 scopus 로고
    • Diversity of endogenous epitopes bound to MHC class II molecules limited by invariant chain
    • Bodmer, H., Viville, S., Benoist, C., and Mathis, D., Diversity of endogenous epitopes bound to MHC class II molecules limited by invariant chain, Science, 263, 1284-1286, 1994.
    • (1994) Science , vol.263 , pp. 1284-1286
    • Bodmer, H.1    Viville, S.2    Benoist, C.3    Mathis, D.4
  • 175
    • 0026543206 scopus 로고
    • The class II MHC-restricted presentation of endogenously synthesized ovalbumin displays clonal variation, requires endosomal/lysosomal processing, and is up-regulated by heat shock
    • Michalek, M. T., Benacerraf, B., and Rock, K. L., The class II MHC-restricted presentation of endogenously synthesized ovalbumin displays clonal variation, requires endosomal/lysosomal processing, and is up-regulated by heat shock, J. Immunol., 148, 1016-1024, 1992.
    • (1992) J. Immunol. , vol.148 , pp. 1016-1024
    • Michalek, M.T.1    Benacerraf, B.2    Rock, K.L.3
  • 176
    • 0025748794 scopus 로고
    • Processing of an endogenous protein can generate MHC class II-restricted T cell determinants distinct from those derived from exogenous antigen
    • Moreno, J., Vignali, D. A. A., Nadimi, F., Fuchs, S., Adorini, L., and Hämmerling, G. J., Processing of an endogenous protein can generate MHC class II-restricted T cell determinants distinct from those derived from exogenous antigen, J. Immunol., 147, 3306-3313, 1991.
    • (1991) J. Immunol. , vol.147 , pp. 3306-3313
    • Moreno, J.1    Vignali, D.A.A.2    Nadimi, F.3    Fuchs, S.4    Adorini, L.5    Hämmerling, G.J.6
  • 177
    • 0024374199 scopus 로고
    • Mutine cell lines stably expressing the influenza virus hemagglutinin gene introduced by a recombinant retrovirus vector are constitutive targets for MHC class I- and class II-restricted T lymphocytes
    • Eager, K. B., Hackett, C. J., Gerhard, W. U., Bennink, J., Eisenlohr, L. C., Yewdell, J., and Ricciardi, R. P., Mutine cell lines stably expressing the influenza virus hemagglutinin gene introduced by a recombinant retrovirus vector are constitutive targets for MHC class I- and class II-restricted T lymphocytes, J. Immunol., 143, 2328-2335, 1989.
    • (1989) J. Immunol. , vol.143 , pp. 2328-2335
    • Eager, K.B.1    Hackett, C.J.2    Gerhard, W.U.3    Bennink, J.4    Eisenlohr, L.C.5    Yewdell, J.6    Ricciardi, R.P.7
  • 179
    • 0027216140 scopus 로고
    • MHC class II-restricted presentation of endogenously synthesized antigen: Epstein-Barr virus transformed B cell lines can present the viral glycoprotein gp340 by two distinct pathways
    • Lee, S. P., Wallace, L. E., Mackett, M., Arrand, J. R., Searle, P. F., Rowe, M., and Rickinson, A. B., MHC class II-restricted presentation of endogenously synthesized antigen: Epstein-Barr virus transformed B cell lines can present the viral glycoprotein gp340 by two distinct pathways, Int. Immunol., 5, 451-460, 1993.
    • (1993) Int. Immunol. , vol.5 , pp. 451-460
    • Lee, S.P.1    Wallace, L.E.2    Mackett, M.3    Arrand, J.R.4    Searle, P.F.5    Rowe, M.6    Rickinson, A.B.7
  • 180
    • 0025907412 scopus 로고
    • Antigen presentation of hen egg-white lysozyme but not of ribonuclease A is augmented by the major histocompatibility complex class II-associated invariant chain
    • Nadimi, F., Moreno, J., Momburg, F., Heuser, A., Fuchs, S., Adorini, L., and Hämmerling, G. J., Antigen presentation of hen egg-white lysozyme but not of ribonuclease A is augmented by the major histocompatibility complex class II-associated invariant chain, Eur. J. Immunol., 21, 1255-1263, 1991.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 1255-1263
    • Nadimi, F.1    Moreno, J.2    Momburg, F.3    Heuser, A.4    Fuchs, S.5    Adorini, L.6    Hämmerling, G.J.7
  • 181
    • 0027496305 scopus 로고
    • Major histocompatibility complex class II-restricted presentation of secreted and endoplasmic reticulum resident antigens requires the invariant chains and is sensitive to lysosomotropic agents
    • Humbert, M., Bertolino, P., Forquet, F., RabourdinCombe, C., Gerlier, D., Davoust, J., and Salamero, J., Major histocompatibility complex class II-restricted presentation of secreted and endoplasmic reticulum resident antigens requires the invariant chains and is sensitive to lysosomotropic agents, Eur. J. Immunol., 23, 3167-3172, 1993.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 3167-3172
    • Humbert, M.1    Bertolino, P.2    Forquet, F.3    Rabourdincombe, C.4    Gerlier, D.5    Davoust, J.6    Salamero, J.7
  • 183
    • 0028879422 scopus 로고
    • Reconstitution of invariant chain function in transgenic mice in vivo by individual p31 and p41 isoforms
    • Shachar, I., Elliott, E. A., Chasnoff, B., Grewal, I. S., and Flavell, R. A., Reconstitution of invariant chain function in transgenic mice in vivo by individual p31 and p41 isoforms, Immunity, 3, 373-383, 1995.
    • (1995) Immunity , vol.3 , pp. 373-383
    • Shachar, I.1    Elliott, E.A.2    Chasnoff, B.3    Grewal, I.S.4    Flavell, R.A.5
  • 185
    • 0028809769 scopus 로고
    • Proteolysis of major histocompatibility complex class II-associated invariant chain is regulated by the alternatively spliced gene product, p41
    • Fineschi, B., Arneson, L., Naujokas, M. F., and Miller, J., Proteolysis of major histocompatibility complex class II-associated invariant chain is regulated by the alternatively spliced gene product, p41, Proc. Natl. Acad. Sci. U.S.A., 92, 10257-10261, 1995.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 10257-10261
    • Fineschi, B.1    Arneson, L.2    Naujokas, M.F.3    Miller, J.4
  • 186
    • 0027761288 scopus 로고
    • Purification of the complex of cathepsin L and the MHC-class II-associated invariant chain fragment from human kidney
    • Ogrinc, T., Dolenc, I., Ritonja, A., and Turk, V., Purification of the complex of cathepsin L and the MHC-class II-associated invariant chain fragment from human kidney, FEBS Lett., 336, 555-559, 1993.
    • (1993) FEBS Lett. , vol.336 , pp. 555-559
    • Ogrinc, T.1    Dolenc, I.2    Ritonja, A.3    Turk, V.4
  • 188
    • 0029041519 scopus 로고
    • The influence of invariant chain on the positive selection of single T cell receptor specificities
    • Tourne, S., Nakano, N., Viville, S., Benoist, C., and Mathis, D., The influence of invariant chain on the positive selection of single T cell receptor specificities, Eur. J. Immunol., 25, 1851-1856, 1995.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1851-1856
    • Tourne, S.1    Nakano, N.2    Viville, S.3    Benoist, C.4    Mathis, D.5
  • 189
    • 0026345419 scopus 로고
    • Class II major histocompatibility complex molecules of murine dendritic cells: Synthesis, sialylation of invariant chain, and antigen processing capacity are down-regulated upon culture
    • Kampgen, E., Koch, N., Koch, F., Stoger, P., Heufler, C., Schuler, G., and Romani, N., Class II major histocompatibility complex molecules of murine dendritic cells: synthesis, sialylation of invariant chain, and antigen processing capacity are down-regulated upon culture, Proc. Natl. Acad. Sci. U.S.A., 88, 3014-3018, 1991.
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 3014-3018
    • Kampgen, E.1    Koch, N.2    Koch, F.3    Stoger, P.4    Heufler, C.5    Schuler, G.6    Romani, N.7


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