Glycopeptide antibiotic resistance genes in glycopeptide-producing organisms

Antimicrobial Agents and Chemotherapy

Volumn 42, Issue 9, 1998, Pages 2215-2220

  Marshall, C G ^a   Lessard, I A D ^b   Park, I S ^b   Wright, G D ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

A47934; GLYCOPEPTIDE; UNCLASSIFIED DRUG; VANCOMYCIN;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENETICS; GENE AMPLIFICATION; GENE CLUSTER; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SOUTHERN BLOTTING; STREPTOMYCES;

EID: 0031663280     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.42.9.2215     Document Type: Article

References (44)

1. Arthur, M., C. Molinas, and P. Courvalin. 1992. The VanS-VanR two-component regulatory system controls synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. J. Bacteriol. 174:2582-2591.
2. Arthur, M., C. Molinas, F. Depardieu, and P. Courvalin. 1993. Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. J. Bacteriol. 175:117-127.
3. Arthur, M., C. Molinas, S. Dutka-Malen, and P. Courvalin. 1991. Structural relationship between the vancomycin resistance protein VanH and 2-hydroxycarboxylic acid dehydrogenases. Gene 103:133-134.
4. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. 1994. Current protocols in molecular biology. John Wiley & Sons, Inc., New York, N.Y.
5. Bager, F., M. Madsen, J. Christensen, and F. M. Aarestrup. 1997. Avoparcin used as a growth promoter is associated with the occurrence of vancomycin-resistant Enterococcus faecium on Danish poultry and pig farms. Prev. Vet. Med. 31:95-112.
6. Barna, J. C. J., and D. H. Williams. 1984. The structure and mode of action of glycopeptide antibiotics. Annu. Rev. Microbiol. 38:339-357.
7. Bates, J., J. Z. Jordens, and D. T. Griffiths. 1994. Farm animals as a putative reservoir for vancomycin-resistant enterococcal infection in man. J. Antimicrob. Chemother. 34:507-516.
8. Bibb, M. J., P. R. Findlay, and M. W. Johnson. 1984. The relationship between base composition and codon usage in bacterial genes and its use for the simple and reliable identification of protein-coding sequences. Gene 30:157-166.
9. Bugg, T. D. H., G. D. Wright, S. Dutka-Malen, M. Arthur, P. Courvalin, and C. T. Walsh. 1991. Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA. Biochemistry 30:10408-10415.
10. Coque, T. M., J. F. Tomayko, S. C. Ricke, P. C. Okhyusen, and B. E. Murray. 1996. Vancomycin-resistant enterococci from nosocomial, community, and animal sources in the United States. Antimicrob. Agents Chemother. 40: 2605-2609.
11. Cunha, B. A. 1995. Vancomycin. Med. Clin. N. Am. 79:817-831.
12. Dartois, V., V. Phalip, P. Schmitt, and C. Divies. 1995. Purification, properties and DNA sequence of the D-lactate dehydrogenase from Leuconostoc mesenteroides subsp. cremoris. Res. Microbiol. 146:291-302.
13. de Lencastre, H., B. L. de Jonge, P. R. Matthews, and A. Tomasz. 1994. Molecular aspects of methicillin resistance in Staphylococcus aureus. J. Antimicrob. Chemother. 33:7-24.
14. Dutka-Malen, S., C. Molinas, M. Arthur, and P. Courvalin. 1992. Sequence of the vanC gene of Enterococcus gallinarum BM4174 encoding a D-alanine: D-alanine ligase-related protein necessary for vancomycin resistance. Gene 112:53-58.
15. Elisha, B. G., and P. Courvalin. 1995. Analysis of genes encoding D-alanine: D-alanine ligase-related enzymes in Leuconostoc mesenteroides and Lactobacillus spp. Gene 152:79-83.
16. Evers, S., B. Casadewall, M. Charles, S. Dutka-Malen, M. Galimand, and P. Courvalin. 1996. Evolution of structure and substrate specificity in D-alanine:D-alanine ligases and related enzymes. J. Mol. Evol. 42:706-712.
17. B two-component regulatory system in Enterococcus faecalis V583. J. Bacteriol. 178:1302-1309.
18. Evers, S., D. F. Sahm, and P. Courvalin. 1993. The vanB gene of vancomycin-resistant Enterococcus faecalis V583 is structurally related to genes encoding D-Ala:D-Ala ligases and glycopeptide-resistance proteins VanA and VanC. Gene 124:143-144.
19. Felsenstein, J. 1993. PHYLIP (Phylogeny Inference Package), version 3.5c. Distributed by the author. Department of Genetics, University of Washington, Seattle.
20. Kirst, H. A., D. G. Thompson, and T. I. Nicas. 1998. Historical yearly usage of vancomycin. Antimicrob. Agents Chemother. 42:1303-1304.
21. Kochhar, S., N. Chuard, and H. Hottinger. 1992. Glutamate 264 modulates the pH dependence of the NAD(+)-dependent D-lactate dehydrogenase. J. Biol. Chem. 267:20298-20301.
22. Leclercq, R., and P. Courvalin. 1997. Resistance to glycopeptides in enterococci. Clin. Infect. Dis. 24:545-554.
23. Marshall, C. G., G. Broadhead, B. Leskiw, and G. D. Wright. 1997. D-AlaD-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB Proc Natl. Acad. Sci. USA 94:6480-6483.
24. Marshall, C. G., and G. D. Wright. 1997. The glycopeptide antibiotic producer Streptomyces toyocaensis NRRL 15009 has both D-alanyl-D-alanine and D-alanyl-D-lactate ligases. FEMS Microbiol. Lett. 157:295-299.
25. McCafferty, D. G., I. A. Lessard, and C. T. Walsh. 1997. Mutational analysis of potential zinc-binding residues in the active site of the enterococcal D-Ala-D-Ala dipeptidase VanX. Biochemistry 36:10498-10505.
26. McDonald, L. C., M. J. Kuehnert, F. C. Tenover, and W. R. Jarvis. 1997. Vancomycin-resistant enterococci outside the health-care setting: prevalence, sources, and public health implications. Emerg. Infect. Dis. 3:311-317.
27. Murray, E. 1997. Vancomycin-resistant enterococci. Am. J. Med. 102:284-293.
28. Park, I. S., C. H. Lin, and C. T. Walsh. 1997. Bacterial resistance to vancomycin: overproduction, purification, and characterization of VanC2 from Enterococcus casseliflavus as a D-Ala-D-Ser ligase. Proc. Natl. Acad. Sci. USA 94:10040-10044.
29. Park, I. S., and C. T. Walsh. 1997. D-Alanyl-D-lactate and D-alanyl-D-alanine synthesis by D-alanyl-D-alanine ligase from vancomycin-resistant Leuconostoc mesenteroides. Effects of a phenylalanine 261 to tyrosine mutation. J. Biol. Chem. 272:9210-9214.
30. Power, E. G. M., Y. H. Abdulla, H. G. Talsania, W. Spice, S. Aathithan, and G. L. French. 1995. VanA genes in vancomycin-resistant clinical isolates of Oerskovia turbata and Arcanobacterium (Cornebacterium) haemolyticum. J. Antimicrob. Chemother. 36:595-606.
31. Quintiliani, R. J., and P. Courvalin. 1996. Characterization of Tn1547, a composite transposon flanked by the IS16 and IS256-like elements, that confers vancomycin resistance in Enterococus faecalis BM428. Gene 172: 1-8.
32. Quintiliani, R. J., and P. Courvalin. 1994. Conjugal transfer of the vancomycin resistance determinant vanB between enterococci involves the movement of large genetic elements from chromosome to chromosome. FEMS Microbiol. Lett. 119:359-363.
33. Quintiliani, R. J., S. Evers, and P. Courvalin. 1993. The vanB gene confers various levels of self-transferable resistance to vancomycin in enterococci. J. Infect. Dis. 167:1220-1223.
34. Reynolds, P. E., F. Depardieu, S. Dutka-Malen, M. Arthur, and P. Courvalin. 1994. Glycopeptide resistance mediated by enterococcal transposon Tn1546 requires production of VanX for hydrolysis of D-alanyl-D-alanine. Mol. Microbiol. 13:1065-1070.
35. Stoll, V. S., M. S. Kimber, and E. F. Pai. 1996. Insights into substrate binding by D-2-ketoacid dehydrogenases from the structure of Lactobacillus pentosus D-lactate dehydrogenase. Structure 4:437-447.
36. Strohl, W. R. 1992. Compilation and analysis of DNA sequences associated with apparent streptomycete promoters. Nucleic Acids Res. 20:961-974.
37. Taguchi, H., and T. Ohta. 1994. Essential role of arginine 235 in the substrate-binding of Lactobacillus plantarum D-lactate dehydrogenase. J. Biochem. 115:930-936.
38. Taguchi, H., and T. Ohta. 1993. Histidine 296 is essential for the catalysis in Lactobacillus plantarum D-lactate dehydrogenase. J. Biol. Chem. 268:18030-18034.
39. Thompson, J. D., D. G. Higgins, and T. J. Gibson. 1994. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22:4673-4680.
40. Walsh, C. T., S. L. Fisher, L.-S. Park, M. Prahalad, and Z. Wu. 1996. Bacterial resistance to vancomycin: five genes and one missing hydrogen bond tell the story. Chem. Biol. 3:21-28.
41. Webb, V., and J. Davies. 1993. Antibiotic preparations contain DNA: a source of drug resistance genes? Antimicrob. Agents Chemother. 37:2379-2384.
42. Woodford, N., B. L. Jones, Z. Baccus, H. A. Ludlam, and D. F. Brown. 1995. Linkage of vancomycin and high-level gentamicin resistance genes on the same plasmid in a clinical isolate of Enterococcus faecalis. J. Antimicrob. Chemother. 35:179-184.
43. Wu, Z., G. D. Wright, and C. T. Walsh. 1995. Overexpression, purification, and characterization of VanX, a D,D-dipeptidase which is essential for vancomycin resistance in Enterococcus faecium BM4147. Biochemistry 34:2455-2463.
44. Zmijewski, M. J., Jr., and J. T. Fayerman. 1994. Glycopeptides, p. 269-281. In L. C. Vining and C. Stuttard (ed.), Genetics and biochemistry of antibiotic production. Butterworth-Heinemann, Boston, Mass.