Milk-borne transmission of HIV: Characterization of productively infected cells in breast milk and interactions between milk and saliva

Journal of Human Virology

Volumn 1, Issue 5, 1998, Pages 328-337

  Southern, Šárka O ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Epithelial cells; HIV; Milk; Milk borne transmission; Saliva

Indexed keywords

ANIMAL; ARTICLE; BREAST MILK; CELL CULTURE; COCULTURE; COLOSTRUM; COMPARATIVE STUDY; CYTOLOGY; DISEASE TRANSMISSION; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN SITU HYBRIDIZATION; PREGNANCY; SALIVA; VIROLOGY; VIRUS LATENCY;

ANIMALS; CELLS, CULTURED; COCULTURE TECHNIQUES; COLOSTRUM; DISEASE TRANSMISSION, VERTICAL; EPITHELIAL CELLS; FEMALE; HIV INFECTIONS; HIV SEROPOSITIVITY; HIV-1; HUMANS; IN SITU HYBRIDIZATION; MILK, HUMAN; PREGNANCY; SALIVA; VIRUS LATENCY;

EID: 0032106168     PISSN: 10909508     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Van de Perre P, Simonon A, Msellati P, et al. Postnatal transmission of human immunodeficiency virus type 1 from mother to infant: a prospective cohort study in Kigali, Rwanda. N Engl J Med 1991;325:595-598.
2. Van de Perre P. The epidemiology of HIV infection and AIDS in Africa. Trends Microbiol 1995;3:217-222.
3. European Collaborative Study. Risk factors for mother-to-child transmission of HIV-1. Lancet 1992;339:1007-1012.
4. Hira SK, Mangrola UG, Mwale C, et al. Apparent vertical transmission of human immunodeficiency virus type 1 by breast-feeding in Zambia. J Pediatr 1990;117:421-424.
5. Dunn DT, Newell ML, Ades AE, Peckham CS. Risk of human immunodeficiency virus type 1 transmission through breastfeeding. Lancet 1992;340:585-588.
6. Simonon A, Mulder-Kampinga GA, Van de Perre P, Karita E, Msellati P, Goudsmit J. Evolution of human immunodeficiency virus type 1 subtype A in women seroconverting post partum and their offspring postnatally infected by breast milk ingestion. J General Virol 1997;78:2225-2233.
7. Kampinga GA, Simonon A, Van de Perre P, Karita E, Msellati P, Goudsmit J. Primary infections with HIV-1 of women and their offspring in Rwanda: findings of heterogeneity at seroconversion, coinfection, and recombinants of HIV-1 subtypes A and C. Virology 1997;227:63-76.
8. Joint United Nations Programme on HIV/AIDS (UN-AIDS). Wkly Epidemiol Rec 1992;7:177-184.
9. Thiry L, Sprecher-Goldberger S, Jonckheer T, et al. Isolation of AIDS virus from cell-free breast milk of three healthy virus carriers. Lancet 1985;2:891-892.
10. Lewis P, Nduati R, Kreiss JK, et al. Cell-free human immunodeficiency virus type 1 in breast milk. J Infect Dis 1998;177:34-39.
11. Van de Perre P, Simonon A, Hitimana DG, et al. Infective and anti-infective properties of breastmilk from HIV-1-infected women. Lancet 1993;341:914-918.
12. Buranasin P, Kunakorn M, Petchlai B, et al. Detection of human immunodeficiency virus type 1 (HIV-1) proviral DNA in breast milk and colostrum of seropositive mothers. J Med Assoc Thai 1993;76:41-44.
13. Ruff A, Coberly J, Halsey N, et al. Prevalence of HIV-1 DNA and p24 antigen in breast milk and correlation with maternal factors. J Acquir Immune Defic Syndr 1994;7: 68-73.
14. Nduati RW, John GC, Richardson BA, et al. Human immunodeficiency virus type 1-infected cells in breast milk: association with immunosuppression and vitamin A deficiency. J Infect Dis 1995;172:1461-1468.
15. Guay LA, Hom DL, Mmiro F, et al. Detection of human immunodeficiency virus type 1 (HIV-1) DNA and p24 antigen in breast milk of HIV-1-infected Ugandan women and vertical transmission. Pediatrics 1996;98:438-444.
16. Bourinbaiar AS, Phillips DM. Transmission of human immunodeficiency virus from monocytes to epithelia. J Acquir Immune Defic Syndr 1991;4:56-63.
17. Phillips DM, Bourinbaiar AS. Mechanism of HIV spread from lymphocytes to epithelia. Virology 1992;186:261-273.
18. Bomsel M. Transcytosis of infectious human immunodeficiency virus across a tight human epithelial cell line barrier. Nat Med 1997;3:42-47.
19. Ho FC, Wong RL, Lawton JW. Human colostral and breast milk cells. Acta Pediatr Scand 1979;68:389-396.
20. Goldman AS. The immune system of human milk: antimicrobial, antiinflammatory and immunomodulating properties: Pediatr Infect Dis J 1993;12:664-671.
21. Southern SO, Southern PJ. Persistent HTLV-I infection of breast luminal epithelial cells: a role in. HTLV transmission? Virology 1998;241:200-215.
22. Taylor-Papadimitriou J, Berdichevsky F, D'Souza B, Burchell J. Human models of breast cancer. Cancer Surv 1993;16:59-78.
23. Liuzzi G, Chirianni A, Clementi M, et al. Analysis of HIV-1 load in blood, semen and saliva: evidence for different viral compartments in a cross-sectional and longitudinal study. AIDS 1996;10:F51-F56.
24. Zhu T, Wang N, Carr A, et al. Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: evidence for viral compartmentalization and selection during sexual transmission. J Virol 1996;70: 3098-3107.
25. Baba TW, Trichel AM, Li A, et al. Infection and AIDS in adult macaques after nontraumatic oral exposure to cell-free SIV. Science 1996;272:1486-1489.
26. Stahl-Hennig C, Tenner-Racz C, Stolte N, et al. The tonsil as a portal of entry for simian immunodeficiency virus (SIV) [abstract 17]. 15th Annual Symposium on Nonhuman Primate Models for AIDS, Seattle, WA, September 1997.
27. Schacker T, Collier AC, Hughes J, Shea T, Corey L. Clinical and epidemiologic features of primary HIV infection. Ann Intern Med 1996;125:257-264.
28. De SK, Notkins AL. HIV genes are highly expressed in the oral tissues of HIV transgenic mice: enhancement and suppression by hormones [abstract 4]. HIV-1 Infection, Mucosal Immunity and Pathogenesis, Bethesda, MD, U.S.A., September 1997.
29. Oyaski M, Davis CA, Nagashunmugam T, et al. Cell-mediated HIV-1 infection of oral epithelial cells [abstract 5]. HIV-1 Infection, Mucosal Immunity and Pathogenesis, Bethesda, September 1997.
30. Haase AT, Henry K, Zupanic M, et al. Quantitative image analysis of HIV-1 infection in lymphoid tissue. Science 1996;274:985-989.
31. - cell lines. AIDS 1991;5:275-281.
32. Clouse KA, Powell D, Washington I, et al. Monokine regulation of human immunodeficiency virus-1 expression in a chronically infected human T cell clone. J Immunol 1989;142:431-438.
33. Shi SR, Chaiwun B, Young L, Cote R, Taylor CR. Antigen retrieval technique utilizing citrate buffer or urea solution for immunohistochemical demonstration of androgen receptor in formalin-fixed paraffin sections. J Histochem Cytochem 1993;41:1599-1604.
34. LeVasseur RJ, Southern SO, Southern PJ. Mammary epithelial cells support and transfer productive HTLV infection. J Human Virol 1998;1:214-223.
35. Haase AT. Analysis of viral infections by in situ hybridization. In Valentine KL, Eberwine JH, Barchas JD, eds. Symposium on in situ hybridization: applications to neurobiology. New York: Oxford University Press, 1987:197-219.
36. 35S. J Histochem 1990;38:917-922.
37. Stiehm ER, Vink P. Transmission of human immunodeficiency virus infection by breast-feeding. J Pediatr 1991; 118:410-412.
38. Rubini NP, Passman LJ. Transmission of human immunodeficiency virus infection from a newly infected mother to her two-year-old child by breast-feeding. Pediatr Infect Dis J 1992;11:682-683.
39. Stevenson M, Brichacek B, Heinzinger N, et al. Molecular basis of cell cycle dependent HIV-1 replication. Implications for control of virus burden. Adv Exp Med Biol 1995; 374:33-45.
40. Toniolo A, Serra C, Conaldi PG, Basolo F, Falcone V, Dolei A. Productive HIV-1 infection of normal human mammary epithelial cells. AIDS 1995;9:859-866.
41. Buehring GC, Kramme PM, Schultz RD. Evidence for bovine leukemia virus in mammary epithelial cells of infected cows. Lab Invest 1994;71:359-365.
42. Hakansson A, Zhivotovsky B, Orrenius S, Sabharwal H, Svanborg C. Apoptosis induced by a human milk protein. Proc Natl Acad Sci USA 1995;92:8064-8068.
43. Nakano S, Ando Y, Saito K, et al. Primary infection of Japanese infants with adult T-cell leukaemia-associated retrovirus (ATLV): evidence for viral transmission from mothers to children. J Infect 1986;12:205-212.
44. Kinoshita K, Amagasaki T, Hino S, et al. Milk-borne transmission of HTLV-I from carrier mothers to their children. Gann 1987;78:674-680.
45. Kinoshita K, Yamanouchi K, Ikeda S, et al. Oral infection of a common marmoset with human T-cell leukemia virus type-I (HTLV-I) by inoculating fresh human milk of HTLV-I carrier mothers. Gann 1985;76:1147-1153.
46. Quayle AJ, Xu C, Mayer KH, Anderson DJ. T lymphocytes and macrophages, but not motile spermatozoa, are a significant source of human immunodeficiency virus in semen. J Infect Dis 1997;176:960-968.