Detection of human immunodeficiency virus type 1 (HIV-1) DNA and p24 antigen in breast milk of HIV-1-infected Ugandan women and vertical transmission

Pediatrics

Volumn 98, Issue 3, 1996, Pages 438-444

  Guay, Laura A ^a   Hom, David L ^a   Mmiro, Francis ^c   Piwowar, Estelle M ^a   Kabengera, Sam ^b   Parsons, Jana ^a   Ndugwa, Christopher ^c   Marum, Lawrence ^a,c   Olness, Karen ^a   Kataaha, Peter ^b   Jackson, J Brooks ^a,d  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MINISTRY OF HEALTH   (Uganda)

^c MAKERERE UNIVERSITY MEDICAL SCHOOL   (Uganda)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

breast milk; HIV 1; p24 antigen; PCR; Uganda; vertical transmission

Indexed keywords

ANTIGEN P24; VIRUS DNA;

ARTICLE; BREAST FEEDING; BREAST MILK; ENZYME IMMUNOASSAY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; UGANDA; VERTICAL TRANSMISSION; VIRUS DETECTION;

BREAST FEEDING; COHORT STUDIES; DISEASE TRANSMISSION, VERTICAL; DNA, VIRAL; FEMALE; HIV CORE PROTEIN P24; HIV INFECTIONS; HIV-1; HUMANS; INFANT; INFANT, NEWBORN; MILK, HUMAN; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; TIME FACTORS; UGANDA;

EID: 9544220642     PISSN: 00314005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Palasanthiran P, Ziegler JB, Stewart GJ, et al. Breast-feeding during primary maternal human immunodeficiency virus infection and risk of transmission from mother to infant. J Infect Dis. 1993;167:441-444
2. Hira SK, Mangrola UG, Mwale C, et al. Apparent vertical transmission of human immunodeficiency virus type 1 by breast-feeding in Zambia. J Pediatr. 1990;117:421-424
3. Van de Perre P, Simonon A, Msellati P, et al. Postnatal transmission of human immunodeficiency virus type 1 from mother to infant: a prospective cohort study in Kigali, Rwanda. N Engl J Med. 1991;325:593-598
4. Rubini N, Passman L. Transmission of human immunodeficiency virus infection from a newly infected mother to her two-year old child by breast-feeding. Pediatr Inf Dis J. 1992;11:682-683. Letter
5. Lepage P, Van de Perre P, Carael M, et al. Postnatal transmission of HIV from mother to child. Lancet. 1987;2:400. Letter
6. Senturia YD, Ades AE, Peckham CS. Breast-feeding and HIV infection. Lancet. 1987;2:400-401. Letter
7. Malaviya AN, Pande I, Adya CM, Kumar A, Kakkar R, Khan MA. Circumstantial evidence of HIV transmission via breast milk. J Acquir Immune Defic Syndr. 1992;5:102. Letter
8. Ziegler J, Cooper D, Johnson R, Gold J. Postnatal transmission of AIDS-associated retrovirus from mother to onfant. Lancet. 1985;1:896-897
9. Dunn DT, Newell ML, Ades AE, Peckham CS. Risk of human immunodeficiency virus type 1 transmission through breastfeeding. Lancet. 1992;340:585-588
10. Ryder R, Manzila T, Baende E, et al. Evidence from Zaire that breastfeeding by HIV-1-seropositive mothers is not a major route for perinatal HIV-1 transmission but does decrease morbidity. AIDS. 1991;5:709-714
11. Global Programme on AIDS. Consensus statement from the WHO/UNICEF Constitution on HIV Transmission and Breastfeeding. Wkly Epidemiol Rec. 1992;67:177-184
12. Lallemant M, Lapointe N, M'Pele P, Lallemant-LeCoeur S. Perinatal HIV transmission. In: Mann J, Tarantola DJM, Netter TW, eds. AIDS in the World. Cambridge, MA: Harvard University Press; 1992:629-645
13. Dabis F, Msellati P, Dunn D, et al. Estimating the rate of mother-to-child transmission of HIV. Report of a workshop on methodological issues Ghent (Belgium); 17-20 Feb 17-20, 1992. AIDS. 1993;7:1139-1148
14. Marum L, Guay L, Mmiro F, et al. Mother to child HIV-1 transmission in Uganda (abstract). In: The Global Challenge of AIDS: Together for the Future. Yokohama, Japan: Tenth International Conference on AIDS/International Conference on STD; Aug 7-12, 1994. Vol 1:219C
15. World Health Organization. Provisional WHO clinical case definition for AIDS. Wkly Epidemiol Rec. 1986;10:69-70
16. Centers for Disease Control. Interpretation and use of the western blot assay for serodiagnosis of human immuno-deficiency virus type 1 infection. MMWR. 1989;38:1-7
17. Jackson JB, Drew J, Lin HJ, et al. Establishment of a quality assurance program for human immunodeficiency virus type 1 DNA polymerase chain reaction assays by the AIDS Clinical Trials Group. J Clin Microbiol. 1993;31:3123-3128
18. Hosmer DW, Lemeshow S. Applied Logistic Regression. New York. Wiley and Sons; 1989:38-126
19. Norusis MJ. SPSS for Windows Release 6.0. Chicago, IL: SPSS Inc; 1993
20. Dean AG, Dean JA, Burton AH, Dicker RC. EPI INFO, Version 5.01b: A Word Processing, Database, and Statistics Program for Epidemiology on Microcomputers. Stone Mountain, GA: USD, Inc; 1990
21. Thiry L, Sprecher-Goldberger S, Jonckheer T, et al. Isolation of AIDS virus from cell-free breast milk of three healthy virus carriers. Lancet. 1985;2:891-892. Letter
22. Colebunders R, Kapita B, Nekwei W, et al. Breastfeeding and transmission of HIV. Lancet. 1988;2:1487
23. Vogt M, Witt D, Craven D, et al. Isolation of HTLV-III/LAV from cervical secretions of women at risk for AIDS, Lancet. 1986;1:525-527
24. Ruff A, Coberly J, Halsey N, et al. Prevalence of HIV-1 DNA and p24 antigen in breast milk and correlation with maternal factors. J Acquir Immune Defic Syndr. 1994;7:68-73
25. Bulterys M, Chao A, Farzadegan H, et al. Detection of HIV-1 in breast milk, multiple sexual partners, and mother-to-child transmission of HIV-1: a cohort study (abstract). In: Final Program and Oral Abstracts of the Eighth International Conference on AIDS/Third STD World Congress. Amsterdam, The Netherlands, July 19-24, 1992; Vol 1:ThC 1524
26. Van de Perre P, Simonon A, Hitimana DG, et al. Infective and antiinfective properties of breastmilk from HTV-1-infected women. Lancet. 1993;341:914-918
27. Buranasin P, Kunakom M, Petchclai B, et al. Detection of human immunodeficiency virus type 1 (HIV-1) proviral DNA in breast milk and colostrum of seropositive mothers. J Med Assoc Thai. 1993;76:41-44
28. Ruff A, Coberly J, Burnley A, et al. Prevalence of HIV in breast milk and correlation with maternal-infant transmission (abstract). In: Final Program and Oral Abstracts of the Eighth International Conference on AIDS/Third STD World Congress. Amsterdam, The Netherlands, July 19-24, 1992; Vol 1:ThC 1523
29. de Martino M, Tovo PA, Tozzi AE, et al. HIV-1 transmission through breast-milk: appraisal of risk according to duration of feeding. AIDS. 1992;6:991-997
30. Datta P, Embree J, Kreiss J, et al. Mother-to-child transmission of human immunodeficiency virus type 1: report from the Nairobi study. J infect Dis. 1994;170:1134-1140
31. Tozzi AE, Pezzoti P, Greco D. Does breast-feeding delay progression to AIDS in HIV-infected children? AIDS. 1990;4:1293-1304
32. Connor E, Sperling R, Gelber R, et al. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. N Engl J Med. 1994;331:1173-1180