The solid phase synthesis of a guanidinium based 'tweezer' receptor

Tetrahedron Letters

Volumn 37, Issue 30, 1996, Pages 5409-5412

  Bonnat, Murielle ^a   Bradley, Mark ^a   Kilburn, Jeremy D ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG RECEPTOR; GUANIDINE DERIVATIVE; PEPTIDE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; MODEL;

EID: 0030598080     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01058-1     Document Type: Article

References (22)

1. 1. LaBrenz, S. R.; Kelly, J. W. J. Am. Chem. Soc., 1995, 117, 1655
2. 2. The solid-phase synthesis of a 'tweezer' receptor, incorporating sulphonamide functionality, which binds peptides in non-polar solvents has also been descibed recently: Gennari, C.; Nestler, H. P.; Salom, B; Still, W. C. Angew. Chem. Int. Ed. Eng., 1995, 34, 1765.
3. 3. For earlier work on 'tweezer' receptors see: Zimmerman, S. C.; Wu, W.; Zeng, Z. J. Am. Chem. Soc., 1991, 113, 196.
4. 4. For previous work on receptors for peptides with a carboxylate/carboxylic acid terminus see: Patel, H. K.; Kilburn, J. D.; Langley, G. J.; Edwards, P. D.; Mitchell, T.; Southgate, R. Tetrahedron Lett, 1994, 35, 481; Flack S. S.; Kilburn, J. D. Tetrahedron Lett, 1995, 36, 3409; Pernia, G. J.; Kilburn, J. D.; Rowley, M. J. Chem. Soc., Chem. Commun.,1995, 305; Waymark, C. P.; Kilburn, J D; Gillies, I Tetrahedron Lett, 1995, 36, 3051.
5. 4. For previous work on receptors for peptides with a carboxylate/carboxylic acid terminus see: Patel, H. K.; Kilburn, J. D.; Langley, G. J.; Edwards, P. D.; Mitchell, T.; Southgate, R. Tetrahedron Lett, 1994, 35, 481; Flack S. S.; Kilburn, J. D. Tetrahedron Lett, 1995, 36, 3409; Pernia, G. J.; Kilburn, J. D.; Rowley, M. J. Chem. Soc., Chem. Commun.,1995, 305; Waymark, C. P.; Kilburn, J D; Gillies, I Tetrahedron Lett, 1995, 36, 3051.
6. 4. For previous work on receptors for peptides with a carboxylate/carboxylic acid terminus see: Patel, H. K.; Kilburn, J. D.; Langley, G. J.; Edwards, P. D.; Mitchell, T.; Southgate, R. Tetrahedron Lett, 1994, 35, 481; Flack S. S.; Kilburn, J. D. Tetrahedron Lett, 1995, 36, 3409; Pernia, G. J.; Kilburn, J. D.; Rowley, M. J. Chem. Soc., Chem. Commun.,1995, 305; Waymark, C. P.; Kilburn, J D; Gillies, I Tetrahedron Lett, 1995, 36, 3051.
7. 4. For previous work on receptors for peptides with a carboxylate/carboxylic acid terminus see: Patel, H. K.; Kilburn, J. D.; Langley, G. J.; Edwards, P. D.; Mitchell, T.; Southgate, R. Tetrahedron Lett, 1994, 35, 481; Flack S. S.; Kilburn, J. D. Tetrahedron Lett, 1995, 36, 3409; Pernia, G. J.; Kilburn, J. D.; Rowley, M. J. Chem. Soc., Chem. Commun.,1995, 305; Waymark, C. P.; Kilburn, J D; Gillies, I Tetrahedron Lett, 1995, 36, 3051.
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22. +.