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Volumn 37, Issue 3, 1998, Pages 627-635

Effects of the novel antiarrhythmic agent azimilide on experimental atrial fibrillation and atrial electrophysiologic properties

Author keywords

Antiarrhythmic agents; Cardiac arrhythmias; ECG; Potassium channel blockers

Indexed keywords

AZIMILIDE; DOFETILIDE; POTASSIUM CHANNEL BLOCKING AGENT;

EID: 0032029143     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(97)00252-6     Document Type: Article
Times cited : (85)

References (32)
  • 1
    • 0027990339 scopus 로고
    • The treatment of atrial fibrillation. An evaluation of drug therapy, electrical modalities and therapeutic considerations
    • [1] Nattel S, Hadjis T, Talajic M. The treatment of atrial fibrillation. An evaluation of drug therapy, electrical modalities and therapeutic considerations. Drugs 1994;48:345-371.
    • (1994) Drugs , vol.48 , pp. 345-371
    • Nattel, S.1    Hadjis, T.2    Talajic, M.3
  • 2
    • 0027186122 scopus 로고
    • Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent
    • [2] Jurkiewicz NK, Sanguinetti MC. Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Circ Res 1993;72:75-83.
    • (1993) Circ Res , vol.72 , pp. 75-83
    • Jurkiewicz, N.K.1    Sanguinetti, M.C.2
  • 5
    • 0029163243 scopus 로고
    • Use-dependent effects of the class III antiarrhythmic agent NE-10064 (azimilide) on cardiac repolarization: Block of delayed rectifier potassium and L-type calcium currents
    • [5] Fermini B, Jurkiewicz NK, Jow B, et al. Use-dependent effects of the class III antiarrhythmic agent NE-10064 (azimilide) on cardiac repolarization: block of delayed rectifier potassium and L-type calcium currents. J Cardiovasc Pharmacol 1995;26:259-271.
    • (1995) J Cardiovasc Pharmacol , vol.26 , pp. 259-271
    • Fermini, B.1    Jurkiewicz, N.K.2    Jow, B.3
  • 6
    • 0031017355 scopus 로고    scopus 로고
    • Azimilide (NE-10064) can prolong or shorten the action potential duration in canine ventricular myocytes: Dependence on blockage of K, Ca and Na channels
    • [6] Yao JA, Tseng GN. Azimilide (NE-10064) can prolong or shorten the action potential duration in canine ventricular myocytes: dependence on blockage of K, Ca and Na channels. J Cardiovasc Electrophysiol 1997;8:184-198.
    • (1997) J Cardiovasc Electrophysiol , vol.8 , pp. 184-198
    • Yao, J.A.1    Tseng, G.N.2
  • 7
    • 0027381889 scopus 로고
    • Protection against programmed electrical stimulation-induced ventricular tachycardia and sudden cardiac death by NE-10064, a class III antiarrhythmic drug
    • [7] Black SC, Butterfield JL, Lucchesi BR. Protection against programmed electrical stimulation-induced ventricular tachycardia and sudden cardiac death by NE-10064, a class III antiarrhythmic drug. J Cardiovasc Pharmacol 1993;22:810-818.
    • (1993) J Cardiovasc Pharmacol , vol.22 , pp. 810-818
    • Black, S.C.1    Butterfield, J.L.2    Lucchesi, B.R.3
  • 8
    • 0029820094 scopus 로고    scopus 로고
    • Suppression of inducible ventricular arrhythmias by intravenous azimilide in dogs with previous myocardial infarction
    • [8] Drexler AP, Micklas JM, Brooks RR. Suppression of inducible ventricular arrhythmias by intravenous azimilide in dogs with previous myocardial infarction. J Cardiovasc Pharmacol 1996;28:848-855.
    • (1996) J Cardiovasc Pharmacol , vol.28 , pp. 848-855
    • Drexler, A.P.1    Micklas, J.M.2    Brooks, R.R.3
  • 9
    • 0029878868 scopus 로고    scopus 로고
    • Efficacy of the class III antiarrhythmic agent azimilide in rodent models of entricular arrhythmia
    • [9] Brooks RR, Carpenter JF, Miller KE, Maynard AE. Efficacy of the class III antiarrhythmic agent azimilide in rodent models of entricular arrhythmia. Proc Soc Exp Biol Med 1996;212:84-93.
    • (1996) Proc Soc Exp Biol Med , vol.212 , pp. 84-93
    • Brooks, R.R.1    Carpenter, J.F.2    Miller, K.E.3    Maynard, A.E.4
  • 10
    • 8944254693 scopus 로고    scopus 로고
    • Effects of azimilide dihydrochloride on circus movement atrial flutter in the canine sterile pericarditis model
    • [10] Restivo M, Hegazy M, Caref EB, et al. Effects of azimilide dihydrochloride on circus movement atrial flutter in the canine sterile pericarditis model. J Cardiovasc Electrophysiol 1996;7:612-624.
    • (1996) J Cardiovasc Electrophysiol , vol.7 , pp. 612-624
    • Restivo, M.1    Hegazy, M.2    Caref, E.B.3
  • 12
    • 0026635429 scopus 로고
    • The mechanism of flecainide's antiarrhythmic action in experimental atrial fibrillation
    • [12] Wang Z, Pagé P, Nattel S. The mechanism of flecainide's antiarrhythmic action in experimental atrial fibrillation. Circ Res 1992;71:271-287.
    • (1992) Circ Res , vol.71 , pp. 271-287
    • Wang, Z.1    Pagé, P.2    Nattel, S.3
  • 13
    • 0027163371 scopus 로고
    • Comparative mechanisms of antiarrhythmic drug action in experimental atrial fibrillation. Importance of use-dependent effects on refractoriness
    • [13] Wang J, Bourne GW, Wang Z, Villemaire C, Talajic M, Nattel S. Comparative mechanisms of antiarrhythmic drug action in experimental atrial fibrillation. Importance of use-dependent effects on refractoriness. Circulation 1993;88:1030-1044.
    • (1993) Circulation , vol.88 , pp. 1030-1044
    • Wang, J.1    Bourne, G.W.2    Wang, Z.3    Villemaire, C.4    Talajic, M.5    Nattel, S.6
  • 14
    • 0028020993 scopus 로고
    • Class III antiarrhythmic drug action in experimental atrial fibrillation. Differences in reverse use dependence and effectiveness between d-sotalol and the new antiarrhythmic drug ambasilide
    • [14] Wang J, Feng J, Nattel S. Class III antiarrhythmic drug action in experimental atrial fibrillation. Differences in reverse use dependence and effectiveness between d-sotalol and the new antiarrhythmic drug ambasilide. Circulation 1994;90:2032-2040.
    • (1994) Circulation , vol.90 , pp. 2032-2040
    • Wang, J.1    Feng, J.2    Nattel, S.3
  • 15
    • 0001867475 scopus 로고    scopus 로고
    • A continuous maintenance infusion technique for stable anesthesia with alpha-chloralose in the dog
    • [15] St-Georges D, Matthews C, Nattel S. A continuous maintenance infusion technique for stable anesthesia with alpha-chloralose in the dog. Contemporary Topics in Laboratory Animal Science 1997;36:62-65.
    • (1997) Contemporary Topics in Laboratory Animal Science , vol.36 , pp. 62-65
    • St-Georges, D.1    Matthews, C.2    Nattel, S.3
  • 16
    • 0029054357 scopus 로고
    • Idiopathic atrial fibrillation in dogs: Electrophysiologic determinants and mechanisms of antiarrhythmic action of flecainide
    • [16] Wang Z, Feng J, Nattel S. Idiopathic atrial fibrillation in dogs: electrophysiologic determinants and mechanisms of antiarrhythmic action of flecainide. J Am Coll Cardiol 1995;26:277-286.
    • (1995) J Am Coll Cardiol , vol.26 , pp. 277-286
    • Wang, Z.1    Feng, J.2    Nattel, S.3
  • 17
    • 0030760009 scopus 로고    scopus 로고
    • Differing sympathetic and vagal effects on atrial fibrillation in dogs: Role of refractoriness heterogeneity
    • [17] Liu L, Nattel S. Differing sympathetic and vagal effects on atrial fibrillation in dogs: role of refractoriness heterogeneity. Am J Physiol 1997;273:H805-H816.
    • (1997) Am J Physiol , vol.273
    • Liu, L.1    Nattel, S.2
  • 18
    • 0024806009 scopus 로고
    • Rate-dependent changes in intraventricular conduction produced by procainamide in anesthetized dogs: A quantitative analysis based on the relation between phase 0 inward current and conduction velocity
    • [18] Nattel S, Jing W. Rate-dependent changes in intraventricular conduction produced by procainamide in anesthetized dogs: A quantitative analysis based on the relation between phase 0 inward current and conduction velocity. Circ Res 1989;65:1485-1498.
    • (1989) Circ Res , vol.65 , pp. 1485-1498
    • Nattel, S.1    Jing, W.2
  • 19
    • 0023905327 scopus 로고
    • Length of excitation wave and susceptibility to reentrant atrial arrhythmias in normal conscious dogs
    • [19] Rensma PL, Allessie MA, Lammers WJEP, Bonke FIM, Schalij MJ. Length of excitation wave and susceptibility to reentrant atrial arrhythmias in normal conscious dogs. Circ Res 1988;62:395-410.
    • (1988) Circ Res , vol.62 , pp. 395-410
    • Rensma, P.L.1    Allessie, M.A.2    Lammers, W.J.E.P.3    Bonke, F.I.M.4    Schalij, M.J.5
  • 20
    • 0028274016 scopus 로고
    • Mapping the conversion of atrial flutter to atrial fibrillation and atrial fibrillation to atrial flutter. Insights into mechanisms
    • [20] Ortiz J, Niwano S, Abe H, Rudy Y, Johnson NJ, Waldo AL. Mapping the conversion of atrial flutter to atrial fibrillation and atrial fibrillation to atrial flutter. Insights into mechanisms. Circ Res 1994;74:882-894.
    • (1994) Circ Res , vol.74 , pp. 882-894
    • Ortiz, J.1    Niwano, S.2    Abe, H.3    Rudy, Y.4    Johnson, N.J.5    Waldo, A.L.6
  • 21
    • 0000514610 scopus 로고
    • Characterization of azimilide effects on ion currents of the repolarization phase
    • [21] Zhang ZH, Boutjdir M, Brooks R, Chen L, El-Sherif N. Characterization of azimilide effects on ion currents of the repolarization phase (abstract). Biophys J 1995;68:A111.
    • (1995) Biophys J , vol.68
    • Zhang, Z.H.1    Boutjdir, M.2    Brooks, R.3    Chen, L.4    El-Sherif, N.5
  • 22
    • 0030098796 scopus 로고    scopus 로고
    • Dual actions of the novel class III antiarrhythmic drug NE-10064 on delayed potassium channel currents in guinea pig ventricular and sinoatrial node cells
    • [22] Davies MP, Freeman LC, Kass RS. Dual actions of the novel class III antiarrhythmic drug NE-10064 on delayed potassium channel currents in guinea pig ventricular and sinoatrial node cells. J Pharmacol Exp Ther 1996;276:1149-1154.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 1149-1154
    • Davies, M.P.1    Freeman, L.C.2    Kass, R.S.3
  • 23
    • 0026640423 scopus 로고
    • Voltage-and time-dependent block of the delayed K + current in cardiac myocytes by dofetilide
    • [23] Carmeliet E. Voltage-and time-dependent block of the delayed K + current in cardiac myocytes by dofetilide. J Pharmacol Exp Ther 1992;262:809-817.
    • (1992) J Pharmacol Exp Ther , vol.262 , pp. 809-817
    • Carmeliet, E.1
  • 24
    • 0028022923 scopus 로고
    • Differential effects of the new class III agent dofetilide on potassium currents in guinea pig cardiomyocytes
    • [24] Kiehn J, Villena P, Beyer T, Brachmann J. Differential effects of the new class III agent dofetilide on potassium currents in guinea pig cardiomyocytes. J Cardiovasc Pharmacol 1994;24:566-572.
    • (1994) J Cardiovasc Pharmacol , vol.24 , pp. 566-572
    • Kiehn, J.1    Villena, P.2    Beyer, T.3    Brachmann, J.4
  • 25
    • 0025351245 scopus 로고
    • Two components of cardiac delayed rectifier K+ current
    • [25] Sanguinetti MC, Jurkiewicz NK. Two components of cardiac delayed rectifier K+ current. J Gen Physiol 1990;96:195-215.
    • (1990) J Gen Physiol , vol.96 , pp. 195-215
    • Sanguinetti, M.C.1    Jurkiewicz, N.K.2
  • 26
    • 0026669913 scopus 로고
    • Effect of ambasilide, a new class III agent, on plateau currents in isolated guinea pig ventricular myocytes: Block of delayed outward potassium current
    • [26] Zhang Z, Follmer CH, Sarma JSM, Chen F, Singh BN. Effect of ambasilide, a new class III agent, on plateau currents in isolated guinea pig ventricular myocytes: Block of delayed outward potassium current. J Pharmacol Exp Ther 1992;263:40-48.
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 40-48
    • Zhang, Z.1    Follmer, C.H.2    Sarma, J.S.M.3    Chen, F.4    Singh, B.N.5
  • 27
    • 0029775154 scopus 로고    scopus 로고
    • Transient outward and delayed rectifier currents in canine atrium: Properties and role of isolation methods
    • Heart Circ Physiol 39
    • [27] Yue L, Feng J, Li GR, Nattel S. Transient outward and delayed rectifier currents in canine atrium: properties and role of isolation methods. Am J Physiol 1996;270:H2157-H2168. (Heart Circ Physiol 39).
    • (1996) Am J Physiol , vol.270
    • Yue, L.1    Feng, J.2    Li, G.R.3    Nattel, S.4
  • 28
    • 0028020442 scopus 로고
    • Rapid and slow components of delayed rectifier current in human atrial myocytes
    • [28] Wang Z, Fermini B, Nattel S. Rapid and slow components of delayed rectifier current in human atrial myocytes. Cardiovasc Res 1994;28:1540-1546.
    • (1994) Cardiovasc Res , vol.28 , pp. 1540-1546
    • Wang, Z.1    Fermini, B.2    Nattel, S.3
  • 30
    • 0025978588 scopus 로고
    • Delayed rectifier outward K+ current is composed of two currents in guinea pig atrial cells
    • Heart Circ Physiol 29
    • [30] Sanguinetti MC, Jurkiewicz NK. Delayed rectifier outward K+ current is composed of two currents in guinea pig atrial cells. Am J Physiol 1991;260:H393-H399. (Heart Circ Physiol 29).
    • (1991) Am J Physiol , vol.260
    • Sanguinetti, M.C.1    Jurkiewicz, N.K.2
  • 31
    • 0030948569 scopus 로고    scopus 로고
    • Insights into mechanisms of antiarrhythmic drug action from experimental models of atrial fibrillation
    • [31] Nattel S, Bourne G, Talajic M. Insights into mechanisms of antiarrhythmic drug action from experimental models of atrial fibrillation. J Cardiovasc Electrophysiol 1997;8:469-480.
    • (1997) J Cardiovasc Electrophysiol , vol.8 , pp. 469-480
    • Nattel, S.1    Bourne, G.2    Talajic, M.3
  • 32
    • 4244047180 scopus 로고    scopus 로고
    • Rate-dependent effects of azimilide (AZ) and dofetilide (DO) on cardiac refractoriness in the ferret
    • Abstract
    • [32] Wade-Whittaker F, Sansone DL, Erickson BK. Rate-dependent effects of azimilide (AZ) and dofetilide (DO) on cardiac refractoriness in the ferret. FASEB J 1996;10:A64. (Abstract).
    • (1996) FASEB J , vol.10
    • Wade-Whittaker, F.1    Sansone, D.L.2    Erickson, B.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.