-
1
-
-
0345578344
-
In vitro electrophysiology of NE-10064, a novel and highly selective class III antiarrhythmic agent
-
Tatla DS, David BC, Malloy KJ, Moorehead TJ. In vitro electrophysiology of NE-10064, a novel and highly selective class III antiarrhythmic agent. FASEB J 7:A107-615, 1993.
-
(1993)
FASEB J
, vol.7
-
-
Tatla, D.S.1
David, B.C.2
Malloy, K.J.3
Moorehead, T.J.4
-
4
-
-
3042994764
-
Effects of clofilium and NE-10064 on IKs, the slow component of the cardiac delayed rectifier
-
Smith MA, Conder ML, Atwal KS, McCullough JR. Effects of clofilium and NE-10064 on IKs, the slow component of the cardiac delayed rectifier. Biophys J 66:A209-Tu-Pos402, 1994.
-
(1994)
Biophys J
, vol.66
-
-
Smith, M.A.1
Conder, M.L.2
Atwal, K.S.3
McCullough, J.R.4
-
5
-
-
0000514610
-
Characterization of azimilide effects on ion currents of the repolarization phase
-
Zhang Z, Boutjdir M, Brooks RR, Chen L, El-Sherif N. Characterization of azimilide effects on ion currents of the repolarization phase. Biophys J 68:A111-M-Pos485, 1995.
-
(1995)
Biophys J
, vol.68
-
-
Zhang, Z.1
Boutjdir, M.2
Brooks, R.R.3
Chen, L.4
El-Sherif, N.5
-
6
-
-
0029163243
-
Use-dependent effects of the class III antiarrhythmic agent NE-10064 (azimilide) on cardiac repolarization: Block of delayed rectifier potassium and L-type calcium currents
-
Fermini B, Jurkiewicz NK, Jow B, Guinosso PJJ, Baskin EP, Lynch JJJ, Salata JJ. Use-dependent effects of the class III antiarrhythmic agent NE-10064 (azimilide) on cardiac repolarization: Block of delayed rectifier potassium and L-type calcium currents. J Cardiovasc Pharmacol 26:259-271, 1995.
-
(1995)
J Cardiovasc Pharmacol
, vol.26
, pp. 259-271
-
-
Fermini, B.1
Jurkiewicz, N.K.2
Jow, B.3
Guinosso, P.J.J.4
Baskin, E.P.5
Lynch, J.J.J.6
Salata, J.J.7
-
8
-
-
0038453740
-
Pharmacologic identification of IKs in canine ventricular myocytes: Effects of NE-10064 (azimilide)
-
Gintant GA. Pharmacologic identification of IKs in canine ventricular myocytes: Effects of NE-10064 (azimilide). Circulation 90:1-146-0781, 1994.
-
(1994)
Circulation
, vol.90
-
-
Gintant, G.A.1
-
9
-
-
0028208260
-
Comparison of the cardiac electrophysiologic effects of NE-10064 with sotalol and E-4031 and their modification by simulated ischaemia
-
Mcintosh MA, Tanira M, Pacini D, Kane KA. Comparison of the cardiac electrophysiologic effects of NE-10064 with sotalol and E-4031 and their modification by simulated ischaemia. J Cardiovasc Pharmacol 23:653-657, 1994.
-
(1994)
J Cardiovasc Pharmacol
, vol.23
, pp. 653-657
-
-
Mcintosh, M.A.1
Tanira, M.2
Pacini, D.3
Kane, K.A.4
-
10
-
-
0027381889
-
Protection against programmed electrical stimulation-induced ventricular tachycardia and sudden cardiac death by NE-10064, a class III antiarrhythmic drug
-
Black SC, Butterfield JL, Lucchesi BR. Protection against programmed electrical stimulation-induced ventricular tachycardia and sudden cardiac death by NE-10064, a class III antiarrhythmic drug. J Cardiovasc Pharmacol 22:810-818, 1993.
-
(1993)
J Cardiovasc Pharmacol
, vol.22
, pp. 810-818
-
-
Black, S.C.1
Butterfield, J.L.2
Lucchesi, B.R.3
-
11
-
-
0024339647
-
Broad sensitivity of rodent arrhythmia models to class I, II, III, and IV antiarrhythmic agents
-
Brooks RR, Miller KE, Carpenter JF, Jones SM. Broad sensitivity of rodent arrhythmia models to class I, II, III, and IV antiarrhythmic agents. Proc Soc Exp Biol Med 191:201-208, 1989.
-
(1989)
Proc Soc Exp Biol Med
, vol.191
, pp. 201-208
-
-
Brooks, R.R.1
Miller, K.E.2
Carpenter, J.F.3
Jones, S.M.4
-
12
-
-
3042920501
-
Efficacy of a novel class III antiarrhythmic agent NE-10064 against ischemia/reperfusion arrhythmias in rats
-
Brooks RR, Carpenter JF, Maynard AE, Decker GE. Efficacy of a novel class III antiarrhythmic agent NE-10064 against ischemia/reperfusion arrhythmias in rats. FASEB J 7:A97-557, 1993.
-
(1993)
FASEB J
, vol.7
-
-
Brooks, R.R.1
Carpenter, J.F.2
Maynard, A.E.3
Decker, G.E.4
-
13
-
-
0344310195
-
The class III antiarrhythmic NE-10064 suppresses ouabain-induced arrhythmias in guinea pigs
-
Miller KE, Decker GE, Brittain D, Carpenter JF, Brooks RR. The class III antiarrhythmic NE-10064 suppresses ouabain-induced arrhythmias in guinea pigs. Can J Physiol Pharmacol 72(Suppl 1):82-01.1.20, 1994.
-
(1994)
Can J Physiol Pharmacol
, vol.72
, Issue.1 SUPPL.
-
-
Miller, K.E.1
Decker, G.E.2
Brittain, D.3
Carpenter, J.F.4
Brooks, R.R.5
-
14
-
-
0014266599
-
Antiarrhythmic activity of some isoquinoline derivatives determined by a rapid screening procedure in the mouse
-
Lawson JW. Antiarrhythmic activity of some isoquinoline derivatives determined by a rapid screening procedure in the mouse. J Pharmacol Exp Ther 160:22-31, 1968.
-
(1968)
J Pharmacol Exp Ther
, vol.160
, pp. 22-31
-
-
Lawson, J.W.1
-
15
-
-
0021690255
-
Ischemia and reperfusion-induced arrhythmias in the rat. Effects of xanthine oxidase inhibition with allopurinol
-
Manning AS, Coltart DJ, Hearse DJ. Ischemia and reperfusion-induced arrhythmias in the rat. Effects of xanthine oxidase inhibition with allopurinol. Circ Res 55:545-548, 1984.
-
(1984)
Circ Res
, vol.55
, pp. 545-548
-
-
Manning, A.S.1
Coltart, D.J.2
Hearse, D.J.3
-
16
-
-
0020655627
-
Reperfusion-induced cardiac arrhythmias in the anesthetized rat and their susceptibility to drugs
-
Kane KA, Paratt JR, Williams EM. Reperfusion-induced cardiac arrhythmias in the anesthetized rat and their susceptibility to drugs. Br J Pharmacol 78:122P, 1984.
-
(1984)
Br J Pharmacol
, vol.78
-
-
Kane, K.A.1
Paratt, J.R.2
Williams, E.M.3
-
17
-
-
84961058932
-
Simple techniques for the surgical occlusion of coronary vessels in the rat
-
Selye H, Bajusz E, Grasso S, Mendell P. Simple techniques for the surgical occlusion of coronary vessels in the rat. Angiol 11:398-407, 1960.
-
(1960)
Angiol
, vol.11
, pp. 398-407
-
-
Selye, H.1
Bajusz, E.2
Grasso, S.3
Mendell, P.4
-
18
-
-
85047679058
-
The Lambeth Conventions: Guidelines for the study of arrhythmias in ischaemia, infarction, and reperfusion
-
Walker MJA, Curtis MJ, Hearse DJ, et al. The Lambeth Conventions: Guidelines for the study of arrhythmias in ischaemia, infarction, and reperfusion. Cardiovasc Res 22:447-455, 1988.
-
(1988)
Cardiovasc Res
, vol.22
, pp. 447-455
-
-
Walker, M.J.A.1
Curtis, M.J.2
Hearse, D.J.3
-
19
-
-
0018173865
-
Ventricular arrhythmias associated with coronary artery occlusion and reperfusion in the isolated perfused rat heart: A model for assessment of antifibrillatory action of antiarrhythmic agents
-
Lubbe WF, Daries PS, Opie LH. Ventricular arrhythmias associated with coronary artery occlusion and reperfusion in the isolated perfused rat heart: A model for assessment of antifibrillatory action of antiarrhythmic agents. Cardiovasc Res 12:212-220, 1978.
-
(1978)
Cardiovasc Res
, vol.12
, pp. 212-220
-
-
Lubbe, W.F.1
Daries, P.S.2
Opie, L.H.3
-
20
-
-
0021046531
-
Responses to ligation of a coronary artery in conscious rats and the actions of antiarrhythmics
-
Johnston KM, MacLeod BA, Walker MJA. Responses to ligation of a coronary artery in conscious rats and the actions of antiarrhythmics. Can J Physiol Pharmacol 61:1340-1353, 1983.
-
(1983)
Can J Physiol Pharmacol
, vol.61
, pp. 1340-1353
-
-
Johnston, K.M.1
MacLeod, B.A.2
Walker, M.J.A.3
-
21
-
-
0023624425
-
Effects of nicainoprol on reperfusion arrhythmia in the isolated working rat heart and on ischemia and reperfusion arrhythmia and myocardial infarct size in the anesthetized rat
-
Martorana PA, Linz W, Göbel H, Petry P, Schölkens BA. Effects of nicainoprol on reperfusion arrhythmia in the isolated working rat heart and on ischemia and reperfusion arrhythmia and myocardial infarct size in the anesthetized rat. Eur J Pharmacol 143:391-401, 1987.
-
(1987)
Eur J Pharmacol
, vol.143
, pp. 391-401
-
-
Martorana, P.A.1
Linz, W.2
Göbel, H.3
Petry, P.4
Schölkens, B.A.5
-
22
-
-
0020428775
-
Ouabain-induced tachyarrhythmias and cell damage in isolated perfused guinea-pig hearts: I. Protection by propranolol
-
Tanz RD, Russell NJ, Banerian SP, Sharp VH. Ouabain-induced tachyarrhythmias and cell damage in isolated perfused guinea-pig hearts: I. Protection by propranolol. J Mol Cell Cardiol 14:655-671, 1982.
-
(1982)
J Mol Cell Cardiol
, vol.14
, pp. 655-671
-
-
Tanz, R.D.1
Russell, N.J.2
Banerian, S.P.3
Sharp, V.H.4
-
23
-
-
0017161183
-
Cardiac Na,K-ATPase activity during positive inotropic and toxic actions of ouabain
-
Rhee HM, Dutta S, Marks BH. Cardiac Na,K-ATPase activity during positive inotropic and toxic actions of ouabain. Eur J Pharmacol 37:141-153, 1976.
-
(1976)
Eur J Pharmacol
, vol.37
, pp. 141-153
-
-
Rhee, H.M.1
Dutta, S.2
Marks, B.H.3
-
24
-
-
3042923195
-
The effects of pronethalol, dichloroisoprenaline and disopyramide on the toxicity to the heart of ouabain and anaesthetics
-
Sekiya A, Vaughan Williams EM. The effects of pronethalol, dichloroisoprenaline and disopyramide on the toxicity to the heart of ouabain and anaesthetics. Br J Anaesth 21:462-472, 1963.
-
(1963)
Br J Anaesth
, vol.21
, pp. 462-472
-
-
Sekiya, A.1
Vaughan Williams, E.M.2
-
25
-
-
0028001747
-
Release of adenine nucleotide metabolites by toxic concentrations of cardiac glycosides
-
Bernauer W. Release of adenine nucleotide metabolites by toxic concentrations of cardiac glycosides. Basic Res Cardiol 89:308-321, 1994.
-
(1994)
Basic Res Cardiol
, vol.89
, pp. 308-321
-
-
Bernauer, W.1
-
26
-
-
0029045235
-
Digoxin-induced ventricular arrhythmias in the guinea pig heart in vivo: Evidence for a role of endogenous catecholamines in the genesis of delayed afterdepolarizations and triggered activity
-
Xu J, Hurt CM, Pelleg A. Digoxin-induced ventricular arrhythmias in the guinea pig heart in vivo: Evidence for a role of endogenous catecholamines in the genesis of delayed afterdepolarizations and triggered activity. Heart Vessels 10:119-127, 1995.
-
(1995)
Heart Vessels
, vol.10
, pp. 119-127
-
-
Xu, J.1
Hurt, C.M.2
Pelleg, A.3
-
27
-
-
0026463632
-
Effects of cyclooxygenase and lipoxygenase inhibitors on digoxin-induced arrhythmias and haemodynamics in guinea-pigs
-
Kanzik I, Çakici I, Ersoy S, Ark M, Abacioglu N, Zengil H. Effects of cyclooxygenase and lipoxygenase inhibitors on digoxin-induced arrhythmias and haemodynamics in guinea-pigs. Pharmacol Res 26:305-316, 1992.
-
(1992)
Pharmacol Res
, vol.26
, pp. 305-316
-
-
Kanzik, I.1
Çakici, I.2
Ersoy, S.3
Ark, M.4
Abacioglu, N.5
Zengil, H.6
-
28
-
-
0002108525
-
NE-10064 exhibits class III antiarrhythmic effects after intravenous or oral administration in conscious dogs
-
Brandt MA, Maynard AE. NE-10064 exhibits class III antiarrhythmic effects after intravenous or oral administration in conscious dogs. FASEB J 8:A7-38, 1994.
-
(1994)
FASEB J
, vol.8
-
-
Brandt, M.A.1
Maynard, A.E.2
-
29
-
-
0014502322
-
A critical evaluation of three methods for the study of adrenergic beta-blocking and anti-arrhythmic agents
-
Vargaftig B, Coignet JL. A critical evaluation of three methods for the study of adrenergic beta-blocking and anti-arrhythmic agents. Eur J Pharmacol 6:49-55, 1969.
-
(1969)
Eur J Pharmacol
, vol.6
, pp. 49-55
-
-
Vargaftig, B.1
Coignet, J.L.2
-
30
-
-
0019861030
-
Prevention of chloroform-induced ventricular tachycardia in mice as an index of antiarrhythmic activity
-
Block AJ. Prevention of chloroform-induced ventricular tachycardia in mice as an index of antiarrhythmic activity. Life Sci 28:2623-2629, 1981.
-
(1981)
Life Sci
, vol.28
, pp. 2623-2629
-
-
Block, A.J.1
-
31
-
-
0000827357
-
Binding profile of NE-10064, a novel class III antiarrhythmic agent, to rat brain receptors
-
Pong SF, Kinney CM, Moorehead TJ. Binding profile of NE-10064, a novel class III antiarrhythmic agent, to rat brain receptors. FASEB J 7:A474-2748, 1993.
-
(1993)
FASEB J
, vol.7
-
-
Pong, S.F.1
Kinney, C.M.2
Moorehead, T.J.3
-
32
-
-
3042952316
-
β-Adrenergic effects of the class III antiarrhythmic agent NE-10064 in the isolated perfused guinea pig heart
-
Miller KE, Carpenter JF, Brooks RR. β-Adrenergic effects of the class III antiarrhythmic agent NE-10064 in the isolated perfused guinea pig heart. FASEB J 7:A108-620, 1993.
-
(1993)
FASEB J
, vol.7
-
-
Miller, K.E.1
Carpenter, J.F.2
Brooks, R.R.3
-
33
-
-
0021132403
-
Methods for the detection and assessment of antiarrhythmic activity
-
Winslow E. Methods for the detection and assessment of antiarrhythmic activity. Pharmacol Ther 24:401-433, 1984.
-
(1984)
Pharmacol Ther
, vol.24
, pp. 401-433
-
-
Winslow, E.1
-
34
-
-
0025740845
-
+ currents in isolated adult rat ventricular myocytes
-
+ currents in isolated adult rat ventricular myocytes. J Gen Physiol 97:973-1011, 1991.
-
(1991)
J Gen Physiol
, vol.97
, pp. 973-1011
-
-
Apkon, M.1
Nerbonne, J.M.2
-
35
-
-
0027225392
-
Ionic currents and action potentials in rabbit, rat, and guinea pig ventricular myocytes
-
Varro A, Lathrop DA, Hester SB, Nanasi PP, Papp JG. Ionic currents and action potentials in rabbit, rat, and guinea pig ventricular myocytes. Basic Res Cardiol 88:93-102, 1993.
-
(1993)
Basic Res Cardiol
, vol.88
, pp. 93-102
-
-
Varro, A.1
Lathrop, D.A.2
Hester, S.B.3
Nanasi, P.P.4
Papp, J.G.5
-
36
-
-
0025864092
-
Pretranslational mechanisms determine the type of potassium channels expressed in the rat skeletal and cardiac muscles
-
Matsubara H, Liman ER, Hess P, Koren G. Pretranslational mechanisms determine the type of potassium channels expressed in the rat skeletal and cardiac muscles. J Biol Chem 266:13324-13328, 1991.
-
(1991)
J Biol Chem
, vol.266
, pp. 13324-13328
-
-
Matsubara, H.1
Liman, E.R.2
Hess, P.3
Koren, G.4
-
37
-
-
0028003753
-
+ channel gene expression in ventricle of rat heart
-
+ channel gene expression in ventricle of rat heart. Circ Res 75:1006-1013, 1994.
-
(1994)
Circ Res
, vol.75
, pp. 1006-1013
-
-
Takimoto, K.1
Levitan, E.S.2
-
38
-
-
0028018183
-
Time course of postnatal changes in rat heart action potential and in transient outward current is different
-
Wahler GM, Dollinger SJ, Smith JM, Flemal KL. Time course of postnatal changes in rat heart action potential and in transient outward current is different. Am J Physiol 267:H1157-H1166, 1994.
-
(1994)
Am J Physiol
, vol.267
-
-
Wahler, G.M.1
Dollinger, S.J.2
Smith, J.M.3
Flemal, K.L.4
-
39
-
-
0027192173
-
Actions and interactions of E-4031 and tedisamil on reperfusion-induced arrhythmias and QT interval in rat in vivo
-
Bril A, Landais L, Gout B. Actions and interactions of E-4031 and tedisamil on reperfusion-induced arrhythmias and QT interval in rat in vivo. Cardiovasc Drugs Ther 7:233-240, 1993.
-
(1993)
Cardiovasc Drugs Ther
, vol.7
, pp. 233-240
-
-
Bril, A.1
Landais, L.2
Gout, B.3
-
40
-
-
0027132962
-
Inwardly rectifying potassium current in rat fetal and neonatal ventricular cardiomyocytes
-
Masuda H, Sperelakis N. Inwardly rectifying potassium current in rat fetal and neonatal ventricular cardiomyocytes. Am J Physiol 265:H1107-H1111, 1993.
-
(1993)
Am J Physiol
, vol.265
-
-
Masuda, H.1
Sperelakis, N.2
-
41
-
-
0027339835
-
Selective IK blockade as an antiarrhythmic mechanism: Effects of UK66.914 on ischaemia and reperfusion arrhythmias in rat and rabbit hearts
-
Rees SA, Curtis MJ. Selective IK blockade as an antiarrhythmic mechanism: Effects of UK66.914 on ischaemia and reperfusion arrhythmias in rat and rabbit hearts. Br J Pharmacol 108:139-145, 1993.
-
(1993)
Br J Pharmacol
, vol.108
, pp. 139-145
-
-
Rees, S.A.1
Curtis, M.J.2
-
42
-
-
0027381282
-
Heterogeneity of action potential waveforms and potassium currents in rat ventricle
-
Clark RB, Bouchard RA, Saunas Stefanon E, Sanchez Chapula J, Giles WR. Heterogeneity of action potential waveforms and potassium currents in rat ventricle. Cardiovasc Res 27:1795-1799, 1993.
-
(1993)
Cardiovasc Res
, vol.27
, pp. 1795-1799
-
-
Clark, R.B.1
Bouchard, R.A.2
Saunas Stefanon, E.3
Sanchez Chapula, J.4
Giles, W.R.5
-
43
-
-
0020606072
-
Mechanism of cardiac glycoside-induced toxicity: Physiology, biochemistry, and electron microscopy
-
Tanz RD, Russell NJ. Mechanism of cardiac glycoside-induced toxicity: Physiology, biochemistry, and electron microscopy. Fed Proc 42:2470-2474, 1983.
-
(1983)
Fed Proc
, vol.42
, pp. 2470-2474
-
-
Tanz, R.D.1
Russell, N.J.2
-
44
-
-
0016681721
-
Effect of beta receptor blockade on the initiation and perpetuation of ouabain-induced ventricular tachyarrhythmia
-
Apantaku FO, Baumgarten CM, Ten Eick RE. Effect of beta receptor blockade on the initiation and perpetuation of ouabain-induced ventricular tachyarrhythmia. J Pharmacol Exp Ther 193:327-335, 1975.
-
(1975)
J Pharmacol Exp Ther
, vol.193
, pp. 327-335
-
-
Apantaku, F.O.1
Baumgarten, C.M.2
Ten Eick, R.E.3
|