Transient outward and delayed rectifier currents in canine atrium: Properties and role of isolation methods

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 270, Issue 6 39-6, 1996, Pages

  Yue, Lixia ^b   Feng, Jianlin ^b   Li, Gui Rong ^b   Nattel, Stanley ^a  

^a MONTREAL HEART INSTITUTE   (Canada)

^b NONE

Author keywords

antiarrhythmic drugs; cardiac electrophysiology; chloride channels; heart; potassium channels

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; CALCIUM ION; CHLORIDE ION; POTASSIUM ION; RYANODINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CELL ISOLATION; CHLORIDE CURRENT; CONTROLLED STUDY; DOG; FEMALE; HEART ATRIUM; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; MALE; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL;

EID: 0029775154     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1996.270.6.h2157     Document Type: Article

References (37)

1. Allessie, M. A., W. J. E. P. Lammers, F. I. M. Bonke, and J. Hollen. Experimental evaluation of Moe's multiple wavelet hypothesis of atrial fibrillation. In: Cardiac Arrhythmias, edited by D. P. Zipes and J. Jalife. Philadelphia, PA: Grune & Stratton, 1985, p. 265-276.
2. + currents in isolated human ventricular myocytes from patients with terminal heart failure. Circ. Res. 73: 379-385, 1993.
3. Colatsky, T. J., C. H. Follmer, and C. F. Starmer. Channel specificity in antiarrhythmic drug action. Mechanism of potassium channel block and its role in suppressing and aggravating cardiac arrhythmias. Circulation 82: 2235-2242, 1990.
4. Duan, D., B. Fermini, and S. Nattel. Potassium channel blocking properties of propafenone in rabbit atrial myocytes. J. Pharmacol. Exp. Ther. 264: 1113-1123, 1993.
5. Escande, D., A. Coulombe, J. F. Faivre, E. Deroubaix, and E. Coraboeuf. Two types of transient outward currents in adult human atrial cells. Am. J. Physiol. 252 (Heart Circ. Physiol. 21): H142-H148, 1987.
6. K, in rabbit atrial myocytes (Abstract). Biophys. J. 59: 266A, 1991.
7. + currents in dog atrial myocytes. Am. J. Physiol. 266 (Cell Physiol. 35): C42-C51, 1994.
8. Fermini, B., Z. Wang, D. Y. Duan, and S. Nattel. Differences in the rate dependence of the transient outward current in rabbit and human atrium. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H1747-H1754, 1992.
9. Follmer, C. H., and T. J. Colatsky. Blockade of delayed rectifier potassium current, Ik, by flecainide and E-4031 in cat ventricular myocytes. Circulation. 82: 289-293, 1990.
10. Giles, W. R., and A. C. G. Van Ginneken. A transient outward current in isolated cells from the crista terminalis of rabbit heart. J. Physiol. Lond. 368: 243-264, 1985.
11. Gintant, G. A., I. S. Cohen, N. B. Datyner, and R. P. Eline. Time-dependent outward currents in the heart. In: The Heart and Cardiovascular System, edited by H. A. Fozzard, E. Haber, A. M. Katz, and H. E. Morgan. New York, NY: Raven, 1992.
12. Hiraoka, M., and S. Kawano. Mechanism of increased amplitude and duration of the plateau with sudden shortening of diastolic intervals in rabbit ventricular cells. Circ. Res. 60: 14-26, 1987.
13. Hiraoka, M., and S. Kawano. Calcium-sensitive and insensitive transient outward current in rabbit ventricular myocytes. J. Physiol. Lond. 410: 187-212, 1989.
14. Josephson, I. R., J. Sanchez-Chapula, and A. M. Brown. Early outward current in rat single ventricular cells. Circ. Res. 54: 157-162, 1984.
15. Li, G. R., J. Feng, Z. Wang, B. Fermini, and S. Nattel. Comparative mechanisms of 4-aminopyridine-resistant transient outward current in human and rabbit atrial myocytes. Am. J. Physiol. 269: H463-H472, 1995.
16. Nattel, S., T. Hadjis, and M. Talajic. The treatment of atrial fibrillation. An evaluation of drug therapy, electrical modalities and therapeutic considerations. Drugs 48: 345-371, 1994.
17. Nattel, S., and F.-D. Zeng. Frequency-dependent effects of antiarrhythmic drugs on action potential duration and refractoriness of canine cardiac Purkinje fibers. J. Pharmacol. Exp. Ther. 229: 283-291, 1984.
18. Noble, D., and R. W. Tsien. Outward membrane currents activated in the plateau range of potentials in cardiac Purkinje fibres. J. Physiol. Lond. 200: 205-231, 1969.
19. Ks) in rabbit ventricular myocytes (Abstract). Biophys. J. 68: A147, 1995.
20. + current. J. Gen. Physiol. 96: 195-215, 1990.
21. + current is composed of two currents in guinea pig atrial cells. Am. J. Physiol. 260 (Heart Circ. Physiol. 29): H393-H399, 1991.
22. Schoels, W., H. Yang, W. B. Gough, and N. El-Sherif. Circus movement atrial flutter in the canine sterile pericarditis model. Differential effects of procainamide on the components of the reentrant pathway. Circ. Res. 68: 1117-1126, 1991.
23. Sedgwick, M. L., H. S. Rasmussen, and S. M. Cobbe. Clinical and electrophysiologic effects of intravenous dofetilide (UK-68,798), a new class III antiarrhythmic drug, in patients with angina pectoris. Am. J. Cardiol. 69: 513-517, 1992.
24. Shibata, E. F., T. Drury, H. Refsum, V. Aldrete, and W. Giles. Contributions of a transient outward current to repolarization in human atrium. Am. J. Physiol. 257 (Heart Circ. Physiol. 26): H1773-H1781, 1989.
25. Shimizu, A., M. Fukatani, A. Konoe, S. Isomoto, O. A. Centurion, and K. Yano. Electrophysiological effects of a new class III antiarrhythmic agent (E-4031) on the conduction and refractoriness of the in vivo human atrium. Cardiovasc. Res. 27: 1333-1338, 1993.
26. Sorota, S. Swelling-induced chloride-sensitive current in canine atrial cells revealed by whole-cell patch-clamp method. Circ. Res. 70: 679-687, 1992.
27. Sorota, S., and B. P. Hoffman. Role of G proteins in the acetylcholine-induced potassium current of canine atrial cells. Am. J. Physiol. 257 (Heart Circ. Physiol. 26): H1516-H1522, 1989.
28. Tseng, G. N., and B. F. Hoffman. Two components of transient outward current in canine ventricular myocytes. Circ. Res. 64: 633-647, 1989.
29. Veldkamp, M. W., A. C. G. van Ginneken, T. Opthof, and L. N. Bouman. Single channel recordings of the delayed rectifier current in human ventricular myocytes (Abstract). Circulation 90: I582, 1994.
30. Wang, Z., B. Fermini, J. Feng, and S. Nattel. Role of chloride currents in repolarizing rabbit atrial myocytes. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H1992-H2002, 1995.
31. + current similar to Kv1.5 cloned channel currents. Circ. Res. 73: 1061-1076, 1993.
32. Wang, Z., B. Fermini, and S. Nattel. Mechanism of flecainide's rate-dependent actions on action potential duration in canine atrial tissue. J. Pharmacol. Exp. Ther. 267: 575-581, 1993.
33. Wang, Z., B. Fermini, and S. Nattel. Rapid and slow components of delayed rectifier current in human atrial myocytes. Cardiovasc. Res. 28: 1540-1546, 1994.
34. Wang, Z., P. Pagé, and S. Nattel. Mechanism of flecainide's antiarrhythmic action in experimental atrial fibrillation. Circ. Res. 71: 271-287, 1992.
35. Zygmunt, A. C. Intracellular calcium activates a chloride current in canine ventricular myocytes. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H1984-H1995, 1994.
36. Zygmunt, A. C., and W. R. Gibbons. Calcium-activated chloride current in rabbit ventricular myocytes. Circ. Res. 68: 424-437, 1991.
37. Zygmunt, A. C., and W. R. Gibbons. Properties of the calcium-activated chloride current in heart. J. Gen. Physiol. 99: 391-414, 1992.