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Volumn 119, Issue 2, 1996, Pages 651-659

Antigen presentation by astrocytes primes rat T lymphocytes for apoptotic cell death A model for T-cell apoptosis in vivo

Author keywords

Apoptosis; Encephalomyelitis; Glucocorticoids; Multiple sclerosis

Indexed keywords

CORTICOSTEROID; ESTROGEN; GAMMA INTERFERON; GLUCOCORTICOID; HYDROCORTISONE; INDOMETACIN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; LIPOCORTIN 1; MIFEPRISTONE; MYELIN BASIC PROTEIN; PREGNENOLONE; STEROID HORMONE; STEROID HORMONE RECEPTOR BLOCKING AGENT; TRANSFERRIN RECEPTOR;

EID: 0029892006     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/119.2.651     Document Type: Article
Times cited : (89)

References (59)
  • 1
    • 0027515341 scopus 로고
    • The effect of corticosteroids for acute optic neuritis on the subsequent development of multiple sclerosis
    • Beck RW, Cleary PA, Trobe JD, Kaufman DI, Kupersmith MJ, Paty DW, et al. The effect of corticosteroids for acute optic neuritis on the subsequent development of multiple sclerosis [see comments]. N Engl J Med 1993; 329: 1764-9. Comment in: N Engl J Med 1994; 329: 1808-10. Comment in: N Engl J Med 1994; 330: 1238-9, Comment in: ACPJ Club 1994; 120 Suppl 3: 61.
    • (1993) N Engl J Med , vol.329 , pp. 1764-1769
    • Beck, R.W.1    Cleary, P.A.2    Trobe, J.D.3    Kaufman, D.I.4    Kupersmith, M.J.5    Paty, D.W.6
  • 2
    • 0027515341 scopus 로고
    • Beck RW, Cleary PA, Trobe JD, Kaufman DI, Kupersmith MJ, Paty DW, et al. The effect of corticosteroids for acute optic neuritis on the subsequent development of multiple sclerosis [see comments]. N Engl J Med 1993; 329: 1764-9. Comment in: N Engl J Med 1994; 329: 1808-10. Comment in: N Engl J Med 1994; 330: 1238-9, Comment in: ACPJ Club 1994; 120 Suppl 3: 61.
    • (1994) N Engl J Med , vol.329 , pp. 1808-1810
  • 3
    • 0028209804 scopus 로고
    • Beck RW, Cleary PA, Trobe JD, Kaufman DI, Kupersmith MJ, Paty DW, et al. The effect of corticosteroids for acute optic neuritis on the subsequent development of multiple sclerosis [see comments]. N Engl J Med 1993; 329: 1764-9. Comment in: N Engl J Med 1994; 329: 1808-10. Comment in: N Engl J Med 1994; 330: 1238-9, Comment in: ACPJ Club 1994; 120 Suppl 3: 61.
    • (1994) N Engl J Med , vol.330 , pp. 1238-1239
  • 4
    • 0027515341 scopus 로고
    • Beck RW, Cleary PA, Trobe JD, Kaufman DI, Kupersmith MJ, Paty DW, et al. The effect of corticosteroids for acute optic neuritis on the subsequent development of multiple sclerosis [see comments]. N Engl J Med 1993; 329: 1764-9. Comment in: N Engl J Med 1994; 329: 1808-10. Comment in: N Engl J Med 1994; 330: 1238-9, Comment in: ACPJ Club 1994; 120 Suppl 3: 61.
    • (1994) ACPJ Club , vol.120 , Issue.3 SUPPL. , pp. 61
  • 6
    • 33845378793 scopus 로고
    • Reaction of Superoxide with nitric oxide to form peroxonitrite in alkaline aqueous solution
    • Blough NV, Zafiriou OC. Reaction of Superoxide with nitric oxide to form peroxonitrite in alkaline aqueous solution [letter]. Inorg Chem 1985; 24: 3502-4.
    • (1985) Inorg Chem , vol.24 , pp. 3502-3504
    • Blough, N.V.1    Zafiriou, O.C.2
  • 7
    • 0014918062 scopus 로고
    • Glucocorticoids and cellular immunity in vitro. Facilitation of the sensitization phase and inhibition of the effector phase of a lymphocyte anti-fibroblast reaction
    • Cohen IR, Stavy L, Feldman M. Glucocorticoids and cellular immunity in vitro. Facilitation of the sensitization phase and inhibition of the effector phase of a lymphocyte anti-fibroblast reaction. J Exp Med 1970; 132: 1055-70.
    • (1970) J Exp Med , vol.132 , pp. 1055-1070
    • Cohen, I.R.1    Stavy, L.2    Feldman, M.3
  • 9
    • 0028795758 scopus 로고
    • Autocrine T-cell suicide mediated by APO-1/(FAS/CD95)
    • Dhein J, Walczak H, Bäumler C, Debatin KM, Krammer PH. Autocrine T-cell suicide mediated by APO-1/(FAS/CD95) [see comments]. Nature 1995; 373: 438-41. Comment in: Nature 1995; 373: 385-6.
    • (1995) Nature , vol.373 , pp. 438-441
    • Dhein, J.1    Walczak, H.2    Bäumler, C.3    Debatin, K.M.4    Krammer, P.H.5
  • 10
    • 0028835801 scopus 로고
    • Dhein J, Walczak H, Bäumler C, Debatin KM, Krammer PH. Autocrine T-cell suicide mediated by APO-1/(FAS/CD95) [see comments]. Nature 1995; 373: 438-41. Comment in: Nature 1995; 373: 385-6.
    • (1995) Nature , vol.373 , pp. 385-386
  • 11
    • 0025788509 scopus 로고
    • Generation of EPR-detectable nitrosyl-iron complexes in tumor target cells cocultured with activated macrophages
    • Drapier JC, Pellat C, Henry Y. Generation of EPR-detectable nitrosyl-iron complexes in tumor target cells cocultured with activated macrophages. J Biol Chem 1991; 266: 10162-7.
    • (1991) J Biol Chem , vol.266 , pp. 10162-10167
    • Drapier, J.C.1    Pellat, C.2    Henry, Y.3
  • 12
    • 0028230177 scopus 로고
    • Lipocortin-1: Cellular mechanisms and clinical relevance
    • Flower RJ, Rothwell NJ, Lipocortin-1: cellular mechanisms and clinical relevance [see comments]. [Review]. Trends Pharmacol Sci 1994; 15: 71-6. Comment in: Trends Pharmacol Sci 1994; 15: 362.
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 71-76
    • Flower, R.J.1    Rothwell, N.J.2
  • 13
    • 43949155041 scopus 로고
    • Flower RJ, Rothwell NJ, Lipocortin-1: cellular mechanisms and clinical relevance [see comments]. [Review]. Trends Pharmacol Sci 1994; 15: 71-6. Comment in: Trends Pharmacol Sci 1994; 15: 362.
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 362
  • 14
    • 0021191999 scopus 로고
    • Astrocytes present myelin basic protein to encephalitogenic T-cell lines
    • Fontana A, Fierz W, Wekerle H. Astrocytes present myelin basic protein to encephalitogenic T-cell lines. Nature 1984; 307: 273-6.
    • (1984) Nature , vol.307 , pp. 273-276
    • Fontana, A.1    Fierz, W.2    Wekerle, H.3
  • 15
    • 0025990308 scopus 로고
    • Regulation and glucocorticoid-independent induction of lipocortin I in cultured astrocytes
    • Gebicke-Haerter PJ, Schoben A, Dieter P, Honegger P, Hertting G. Regulation and glucocorticoid-independent induction of lipocortin I in cultured astrocytes. J Neurochem 1991; 57: 175-83.
    • (1991) J Neurochem , vol.57 , pp. 175-183
    • Gebicke-Haerter, P.J.1    Schoben, A.2    Dieter, P.3    Honegger, P.4    Hertting, G.5
  • 16
  • 17
    • 0028136653 scopus 로고
    • Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques
    • Gold R, Schmied M, Giegerich G, Breitschopf H, Hartung HP, Toyka KV, et al. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques [see comments]. Lab Invest 1994; 71: 219-25. Comment in: Lab Invest 1995; 72: 611-13.
    • (1994) Lab Invest , vol.71 , pp. 219-225
    • Gold, R.1    Schmied, M.2    Giegerich, G.3    Breitschopf, H.4    Hartung, H.P.5    Toyka, K.V.6
  • 18
    • 0029039946 scopus 로고
    • Gold R, Schmied M, Giegerich G, Breitschopf H, Hartung HP, Toyka KV, et al. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques [see comments]. Lab Invest 1994; 71: 219-25. Comment in: Lab Invest 1995; 72: 611-13.
    • (1995) Lab Invest , vol.72 , pp. 611-613
  • 20
    • 3242837965 scopus 로고
    • Glucocorticosteroid therapy
    • Wyngaarden JB, Smith LH, Bennett JC, editors. Philadelphia: W. B. Saunders.
    • Haynes BF. Glucocorticosteroid therapy. In: Wyngaarden JB, Smith LH, Bennett JC, editors. Cecil textbook of medicine. 19th ed. Philadelphia: W. B. Saunders. 1992: 104-8.
    • (1992) Cecil Textbook of Medicine. 19th Ed. , pp. 104-108
    • Haynes, B.F.1
  • 21
    • 0021907881 scopus 로고
    • Expression of la molecules by astrocytes during acute experimental allergic encephalomyelitis in the Lewis rat
    • Hickey WF, Osborn JP, Kirby WM. Expression of la molecules by astrocytes during acute experimental allergic encephalomyelitis in the Lewis rat. Cell Immunol 1985; 91: 528-35.
    • (1985) Cell Immunol , vol.91 , pp. 528-535
    • Hickey, W.F.1    Osborn, J.P.2    Kirby, W.M.3
  • 23
    • 0027437488 scopus 로고
    • Pregnancy in multiple sclerosis
    • Hutchinson M. Pregnancy in multiple sclerosis [editorial; comment]. J Neurol Neurosurg Psychiatry 1993; 56: 1043-5. Comment on J Neurol Neurosurg Psychiatry 1993; 56: 1062-5.
    • (1993) J Neurol Neurosurg Psychiatry , vol.56 , pp. 1043-1045
    • Hutchinson, M.1
  • 24
    • 0027362720 scopus 로고
    • Hutchinson M. Pregnancy in multiple sclerosis [editorial; comment]. J Neurol Neurosurg Psychiatry 1993; 56: 1043-5. Comment on J Neurol Neurosurg Psychiatry 1993; 56: 1062-5.
    • (1993) J Neurol Neurosurg Psychiatry , vol.56 , pp. 1062-1065
  • 25
    • 0027184205 scopus 로고
    • Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: Comparison with enzymatically formed nitric oxide from L-arginine
    • Ignarro LJ, Fukuto JM, Griscavage JM, Rogers NE, Byrns RE. Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine. Proc Natl Acad Sci USA 1993; 90: 8103-7.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8103-8107
    • Ignarro, L.J.1    Fukuto, J.M.2    Griscavage, J.M.3    Rogers, N.E.4    Byrns, R.E.5
  • 26
    • 0027991759 scopus 로고
    • Estrogen induces a potent suppression of experimental autoimmune encephalomyelitis and collagen-induced arthritis in mice
    • Jansson J, Olsson T, Holmdahl R. Estrogen induces a potent suppression of experimental autoimmune encephalomyelitis and collagen-induced arthritis in mice. J Neuroimmunol 1994; 53: 203-7.
    • (1994) J Neuroimmunol , vol.53 , pp. 203-207
    • Jansson, J.1    Olsson, T.2    Holmdahl, R.3
  • 27
    • 0026751709 scopus 로고
    • Prevention and therapy of experimental autoimmune neuritis by an antibody against T cell receptors-α/β
    • Jung S, Krämer S, Schluesener HJ, Hünig T, Toyka KV, Hartung H-P. Prevention and therapy of experimental autoimmune neuritis by an antibody against T cell receptors-α/β. J Immunol 1992; 148: 3768-75.
    • (1992) J Immunol , vol.148 , pp. 3768-3775
    • Jung, S.1    Krämer, S.2    Schluesener, H.J.3    Hünig, T.4    Toyka, K.V.5    Hartung, H.-P.6
  • 28
    • 0027546746 scopus 로고
    • Pregnenolone metabolism in rodent embryonic neurons and astrocytes
    • Kabbadj K, el-Etr M, Baulieu E-E, Robel P. Pregnenolone metabolism in rodent embryonic neurons and astrocytes. Glia 1993; 7: 170-5.
    • (1993) Glia , vol.7 , pp. 170-175
    • Kabbadj, K.1    El-Etr, M.2    Baulieu, E.-E.3    Robel, P.4
  • 29
    • 0024534407 scopus 로고
    • Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids
    • MacPhee IA, Antoni FA, Mason DW. Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids. J Exp Med 1989; 169: 431-45.
    • (1989) J Exp Med , vol.169 , pp. 431-445
    • MacPhee, I.A.1    Antoni, F.A.2    Mason, D.W.3
  • 30
    • 0026085991 scopus 로고
    • Genetic variation in the stress response: Susceptibility to experimental allergic encephalomyelitis and implications for human inflammatory disease
    • Mason D. Genetic variation in the stress response: susceptibility to experimental allergic encephalomyelitis and implications for human inflammatory disease. [Review]. Immunol Today 1991; 12: 57-60.
    • (1991) Immunol Today , vol.12 , pp. 57-60
    • Mason, D.1
  • 31
    • 0022591581 scopus 로고
    • Immunohistochemical analysis of the rat central nervous system during experimental allergic encephalomyelitis, with special reference to Ia-positive cells with dendritic morphology
    • Matsumoto Y, Hara N, Tanaka R, Fujiwara M. Immunohistochemical analysis of the rat central nervous system during experimental allergic encephalomyelitis, with special reference to Ia-positive cells with dendritic morphology. J Immunol 1986; 136: 3668-76.
    • (1986) J Immunol , vol.136 , pp. 3668-3676
    • Matsumoto, Y.1    Hara, N.2    Tanaka, R.3    Fujiwara, M.4
  • 32
    • 0027285330 scopus 로고
    • In situ inactivation of infiltrating T cells in the central nervous system with autoimmune encephalomyelitis. the role of astrocytes
    • Matsumoto Y, Hanawa H, Tsuchida M, Abo T. In situ inactivation of infiltrating T cells in the central nervous system with autoimmune encephalomyelitis. The role of astrocytes. Immunology 1993; 79: 381-90.
    • (1993) Immunology , vol.79 , pp. 381-390
    • Matsumoto, Y.1    Hanawa, H.2    Tsuchida, M.3    Abo, T.4
  • 33
    • 0028575875 scopus 로고
    • Multiple sclerosis. Immunomodulatory effects of human astrocytes on T cells
    • Meinl E, Aloisi F, Ertl B, Weber F, de Waal Malefyt R, Wekerle H, et al. Multiple sclerosis. Immunomodulatory effects of human astrocytes on T cells. Brain 1994; 117: 1323-32.
    • (1994) Brain , vol.117 , pp. 1323-1332
    • Meinl, E.1    Aloisi, F.2    Ertl, B.3    Weber, F.4    De Waal Malefyt, R.5    Wekerle, H.6
  • 34
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988; 16: 1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 35
    • 43949158868 scopus 로고
    • Immunological functions of non-professional antigen-presenting cells: New insights from studies of T-cell interactions with keratinocytes
    • Nickoloff BJ, Turka LA. Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes. [Review]. Immunol Today 1994; 15: 464-9.
    • (1994) Immunol Today , vol.15 , pp. 464-469
    • Nickoloff, B.J.1    Turka, L.A.2
  • 36
    • 0024787933 scopus 로고
    • IL-2 protects T lymphocytes from glucocorticoid-induced DNA fragmentation and cell death
    • Nieto MA, Lopez-Rivas A. IL-2 protects T lymphocytes from glucocorticoid-induced DNA fragmentation and cell death. J Immunol 1989; 143: 4166-70.
    • (1989) J Immunol , vol.143 , pp. 4166-4170
    • Nieto, M.A.1    Lopez-Rivas, A.2
  • 37
    • 0026541471 scopus 로고
    • In situ demonstration of proliferating cells in the rat central nervous system during experimental autoimmune encephalomyelitis
    • Ohmori K, Hong Y, Fujiwara M, Matsumoto Y. In situ demonstration of proliferating cells in the rat central nervous system during experimental autoimmune encephalomyelitis. Lab Invest 1992; 66: 54-62.
    • (1992) Lab Invest , vol.66 , pp. 54-62
    • Ohmori, K.1    Hong, Y.2    Fujiwara, M.3    Matsumoto, Y.4
  • 38
    • 0028150645 scopus 로고
    • Essential genes that regulate apoptosis
    • Osborne BA, Schwartz LM. Essential genes that regulate apoptosis. Trends Cell Biol 1994; 4: 394-9.
    • (1994) Trends Cell Biol , vol.4 , pp. 394-399
    • Osborne, B.A.1    Schwartz, L.M.2
  • 39
    • 0025817888 scopus 로고
    • Apoptosis in the nervous system in experimental allergic encephalomyelitis
    • Pender MP, Nguyen KB, McCombe PA, Kerr JF. Apoptosis in the nervous system in experimental allergic encephalomyelitis. J Neurol Sci 1991; 104: 81-7.
    • (1991) J Neurol Sci , vol.104 , pp. 81-87
    • Pender, M.P.1    Nguyen, K.B.2    McCombe, P.A.3    Kerr, J.F.4
  • 40
    • 0000116653 scopus 로고
    • The transforming growth factor-βs
    • Sporn MB, Roberts AB, editors. Peptide growth factors and their receptors I. Berlin: Springer-Verlag
    • Roberts AB, Sporn MB. The transforming growth factor-βs. In: Sporn MB, Roberts AB, editors. Peptide growth factors and their receptors I. Handbook of experimental pharmacology. Vol. 95/1. Berlin: Springer-Verlag, 1990: 419-72.
    • (1990) Handbook of Experimental Pharmacology , vol.95 , Issue.1 , pp. 419-472
    • Roberts, A.B.1    Sporn, M.B.2
  • 42
    • 0027773017 scopus 로고
    • Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis. Evidence for programmed cell death as a mechanism to control inflammation in the brain
    • Schmied M, Breitschopf H, Gold R, Zischler H, Rothe G, Wekerle H, et al. Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis. Evidence for programmed cell death as a mechanism to control inflammation in the brain. Am J Pathol 1993; 143: 446-52.
    • (1993) Am J Pathol , vol.143 , pp. 446-452
    • Schmied, M.1    Breitschopf, H.2    Gold, R.3    Zischler, H.4    Rothe, G.5    Wekerle, H.6
  • 44
    • 0019904008 scopus 로고
    • Corticosteroids inhibit murine macrophage la expression and interleukin 1 production
    • Snyder DS, Unanue ER. Corticosteroids inhibit murine macrophage la expression and interleukin 1 production. J Immunol 1982; 129: 1803-5.
    • (1982) J Immunol , vol.129 , pp. 1803-1805
    • Snyder, D.S.1    Unanue, E.R.2
  • 45
    • 0028170995 scopus 로고
    • Apoptotic elimination of V beta 8.2+ cells from the central nervous system during recovery from experimental autoimmune encephalomyelitis induced by the passive transfer of V beta 8.2+ encephalitogenic T cells
    • Tabi Z, McCombe PA, Pender MP. Apoptotic elimination of V beta 8.2+ cells from the central nervous system during recovery from experimental autoimmune encephalomyelitis induced by the passive transfer of V beta 8.2+ encephalitogenic T cells. Eur J Immunol 1994; 24: 2609-17.
    • (1994) Eur J Immunol , vol.24 , pp. 2609-2617
    • Tabi, Z.1    McCombe, P.A.2    Pender, M.P.3
  • 46
    • 0029014953 scopus 로고
    • Cellular distribution and costimulatory function of rat CD28. Regulated expression during thymocyte maturation and induction of cyclosporin A sensitivity of coslimulated T cell responses by phorbol ester
    • Tacke M, Clark GJ, Dallman MJ, Hünig T. Cellular distribution and costimulatory function of rat CD28. Regulated expression during thymocyte maturation and induction of cyclosporin A sensitivity of coslimulated T cell responses by phorbol ester. J Immunol 1995; 154: 5121-7.
    • (1995) J Immunol , vol.154 , pp. 5121-5127
    • Tacke, M.1    Clark, G.J.2    Dallman, M.J.3    Hünig, T.4
  • 47
    • 0026026875 scopus 로고
    • Glial cells and neurons induce blood-brain barrier related enzymes in cultured cerebral endothelial cells
    • Tontsch U, Bauer HC. Glial cells and neurons induce blood-brain barrier related enzymes in cultured cerebral endothelial cells. Brain Res 1991; 539: 247-53.
    • (1991) Brain Res , vol.539 , pp. 247-253
    • Tontsch, U.1    Bauer, H.C.2
  • 48
    • 0028218330 scopus 로고
    • Analysis of susceptibility of mature human T lymphocytes to dexamethasone-induced apoptosis
    • Tuosto L, Cundari E, Montani MSG, Piccolella E. Analysis of susceptibility of mature human T lymphocytes to dexamethasone-induced apoptosis. Eur J Immunol 1994; 24: 1061-5.
    • (1994) Eur J Immunol , vol.24 , pp. 1061-1065
    • Tuosto, L.1    Cundari, E.2    Montani, M.S.G.3    Piccolella, E.4
  • 49
    • 0025255387 scopus 로고
    • Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: The missing link
    • Ullman KS, Northrop JP, Verweij CL, Crabtree GR. Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: the missing link. [Review]. Annu Rev Immunol 1990; 8: 421-52.
    • (1990) Annu Rev Immunol , vol.8 , pp. 421-452
    • Ullman, K.S.1    Northrop, J.P.2    Verweij, C.L.3    Crabtree, G.R.4
  • 50
    • 0025104589 scopus 로고
    • Intrathecal application of interferon gamma. Progressive appearance of MHC antigens within the rat nervous system
    • Vass K, Lassmann H. Intrathecal application of interferon gamma. Progressive appearance of MHC antigens within the rat nervous system. Am J Pathol 1990; 137: 789-800.
    • (1990) Am J Pathol , vol.137 , pp. 789-800
    • Vass, K.1    Lassmann, H.2
  • 51
    • 0022553992 scopus 로고
    • The distribution of Ia antigen in the lesions of rat acute experimental allergic encephalomyelitis
    • Vass K, Lassmann H, Wekerle H, Wisniewski HM. The distribution of Ia antigen in the lesions of rat acute experimental allergic encephalomyelitis. Acta Neuropathol (Berl) 1986; 70: 149-60.
    • (1986) Acta Neuropathol (Berl) , vol.70 , pp. 149-160
    • Vass, K.1    Lassmann, H.2    Wekerle, H.3    Wisniewski, H.M.4
  • 52
    • 0028326439 scopus 로고
    • Human astrocytes are only partially competent antigen presenting cells. Possible implications for lesion development in multiple sclerosis
    • Weber F, Meinl E, Aloisi F, Nevinny-Stickel C, Albert E, Wekerle H, et al. Human astrocytes are only partially competent antigen presenting cells. Possible implications for lesion development in multiple sclerosis. Brain 1994; 117: 59-69.
    • (1994) Brain , vol.117 , pp. 59-69
    • Weber, F.1    Meinl, E.2    Aloisi, F.3    Nevinny-Stickel, C.4    Albert, E.5    Wekerle, H.6
  • 54
    • 0023413923 scopus 로고
    • Immune reactivity in the nervous system: Modulation of T-lymphocyte activation by glial cells
    • Wekerle H, Sun D, Oropeza-Wekerle RL, Meyermann R. Immune reactivity in the nervous system: modulation of T-lymphocyte activation by glial cells. [Review]. J Exp Biol 1987; 132: 43-57.
    • (1987) J Exp Biol , vol.132 , pp. 43-57
    • Wekerle, H.1    Sun, D.2    Oropeza-Wekerle, R.L.3    Meyermann, R.4
  • 55
    • 0028178471 scopus 로고
    • 2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression
    • 2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression. Eur J Immunol 1994; 24: 1293-300.
    • (1994) Eur J Immunol , vol.24 , pp. 1293-1300
    • Weller, M.1    Constam, D.B.2    Malipiero, U.3    Fontana, A.4
  • 56
    • 0019225636 scopus 로고
    • Cell death: The significance of apoptosis
    • Wyllie AH, Kerr JFR, Currie AR. Cell death: the significance of apoptosis. [Review]. Int Rev Cytol 1980; 68: 251-306.
    • (1980) Int Rev Cytol , vol.68 , pp. 251-306
    • Wyllie, A.H.1    Kerr, J.F.R.2    Currie, A.R.3
  • 57
    • 0025613973 scopus 로고
    • Programmed T lymphocyte cell death. Cell activation- And steroid-induced pathways are mutually antagonistic
    • Zacharchuk CM, Mercep M, Chakraborti PK, Simons SS Jr, Ashwell JD. Programmed T lymphocyte cell death. Cell activation- and steroid-induced pathways are mutually antagonistic. J Immunol 1990; 145: 4037-45.
    • (1990) J Immunol , vol.145 , pp. 4037-4045
    • Zacharchuk, C.M.1    Mercep, M.2    Chakraborti, P.K.3    Simons Jr., S.S.4    Ashwell, J.D.5
  • 58
    • 0028037766 scopus 로고
    • Apoptotic cell death of T-lymphocytes in experimental autoimmune neuritis of the Lewis rat
    • Zettl UK, Gold R, Hartung HP, Toyka KV. Apoptotic cell death of T-lymphocytes in experimental autoimmune neuritis of the Lewis rat. Neurosci Lett 1994; 176: 75-9.
    • (1994) Neurosci Lett , vol.176 , pp. 75-79
    • Zettl, U.K.1    Gold, R.2    Hartung, H.P.3    Toyka, K.V.4
  • 59
    • 0029019590 scopus 로고
    • Intravenous glucocorticosteroid treatment augments apoptosis of inflammatory T cells in experimental autoimmune neuritis (EAN) of the Lewis rat
    • Zettl UK, Gold R, Toyka KV, Hartung HP. Intravenous glucocorticosteroid treatment augments apoptosis of inflammatory T cells in experimental autoimmune neuritis (EAN) of the Lewis rat. J Neuropathol Exp Neurol 1995; 54: 540-7.
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 540-547
    • Zettl, U.K.1    Gold, R.2    Toyka, K.V.3    Hartung, H.P.4


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