Transforming growth factor β stimulates the human immunodeficiency virus 1 enhancer and requires NF-κB activity

Molecular and Cellular Biology

Volumn 18, Issue 1, 1998, Pages 110-121

  Li, Jian Ming ^a   Shen, Xing ^a   Hu, Patrick Pei Chih ^a   Wang, Xiao Fan ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR PROTEIN; LUCIFERASE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; ELECTROPHORETIC MOBILITY; ENHANCER REGION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; KERATINOCYTE; LONG TERMINAL REPEAT; MOUSE; NONHUMAN; PRE B LYMPHOCYTE; PRIORITY JOURNAL; TRANSACTIVATION;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0031972761     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.18.1.110     Document Type: Article

References (50)

1. Arsura, M., M. Wu, and G. E. Sonenshein. 1996. TGFβ1 inhibits NF-κB/Rel activity inducing apoptosis of B cells: transcriptional activation of IκB alpha. Immunity 5:31-40.
2. Baeuerle, P. A., and T. Henkel. 1994. Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12:141-179.
3. Bassing, C. H., J. M. Yingling, D. J. Howe, T. Wang, W. W. He, M. L. Gustafson, P. Shah, P. K. Donahoe, and X-F. Wang. 1994. A transforming growth factor β type 1 receptor that signals to activate gene expression. Science 263:87-89.
4. Beg, A. A., and D. Baltimore. 1996. An essential role for NF-κB in preventing TNF-α-induced cell death. Science 274:782-784.
5. Boukamp, P., R. T. Petrussevska, D. Breitkreutz, J. Hornung, A. Makham, and N. E. Fusenig. 1988. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J. Cell Biol. 106:761-771.
6. Carcamo, J., F. M. B. Weis, F. Ventura, R. Wieser, J. L. Wrana, L. Attisano, and J. Massague. 1994. Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor β and activin. Mol. Cell. Biol. 14:3810-3821.
7. Cupp, C., J. P. Taylor, K. Khalili, and S. Amini. 1993. Evidence for stimulation of the transforming growth factor β1 promoter by HIV-1 Tat in cells derived from CNS. Oncogene 8:2231-2236.
8. Datto, M. B., Y. Li, J. Panus, D. J. Howe, Y. Xiong, and X.-Y. Wang. 1995. TGF-β mediated growth inhibition is associated with induction of the cyclin-dependent kinase inhibitor, p21. Proc. Natl. Acad. Sci. USA 92:5545-5549.
9. Datto, M. B., Y. Yu, and X.-F. Wang. 1995. Functional analysis of the transforming growth factor β responsive elements in the WAF1/Cip1/p21 promoter. J. Biol. Chem. 270:28623-28628.
10. 9a. Datto, M. B., and X.-F. Wang. Unpublished data.
11. de Martin, R., B. Haendler, R. Hofer-Warbinek, H. Gaugitsch, M. Wrann, H. Schlusener, and J. M. Seifert. 1987. Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-β gene family. EMBO J. 6:3673-3677.
12. Espevik, T., I. S. Figari, G. E. Ranges, and M. A. Palladino, Jr.. 1988. Transforming growth factor-β1 (TGF-β1) and recombinant human tumor necrosis factor-alpha reciprocally regulate the generation of lymphokine-activated killer cell activity. Comparison between natural porcine platelet-derived TGF-β1 and TGF-β2, and recombinant human TGF-β1. J. Immunology 140:2312-2316.
13. Feng, X. H., and R. Derynck. 1996. Ligand-independent activation of transforming growth factor (TGF) β signaling pathways by heteromeric cytoplasmic domains of TGF-β receptors. J. Biol. Chem. 271:13123-13129.
14. Flanagan, W. M., B. Corthesy, R. J. Bram, and G. R. Crabtree. 1991. Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. Nature 352:803-807.
15. Javahery, R., A. Khachi, K. Lo, B. Zenzie-Gregory, and S. T. Smale. 1994. DNA sequence requirements for transcriptional initiator activity in mammalian cells. Mol. Cell. Biol. 14:116-127.
16. Jones, K. A. 1993. Tat and the HIV-1 promoter. Curr. Opin. Cell Biol. 5:461-468.
17. Kehrl, J. H., A. B. Roberts, L. M. Wakefield, S. Jakowlew, M. B. Sporn, and A. S. Fauci. 1986. Transforming growth factor β is an important immunomodulatory protein for human B lymphocytes. J. Immunol. 137:3855-3860.
18. Kehrl, J. H., L. M. Wakefield, A. B. Roberts, S. Jakowlew, M. Alvarez-Mon, R. Derynck, M. B. Sporn, and A. S. Fauci. 1986. Production of transforming growth factor β by human T lymphocytes and its potential role in the regulation of T cell growth. J. Exp. Med. 163:1037-1050.
19. Kekow, J., W. Wachsman, J. A. McCutchan, M. Cronin, D. A. Carson, and M. Lotz. 1990. Transforming growth factor β and noncytopathic mechanisms of immunodeficiency in human immunodeficiency virus infection. Proc. Natl. Acad. Sci. USA 87:8321-8325.
20. Kinoshita, S., L. Su, M. Amano, L. A. Timmerman, H. Kaneshima, and G. P. Nolan. 1997. The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells. Immunity 6:235-244.
21. Koff, A., M. Ohtsuki, K. Polyak, J. M. Roberts, and J. Massague. 1993. Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-β. Science 260:536-539.
22. Kulkarni, A. B., C. G. Huh, D. Becker, A. Geiser, M. Lyght, K. C. Flanders, A. B. Roberts, M. B. Sporn, J. M. Ward, and S. Karlsson. 1993. Transforming growth factor β1 null mutation in mice causes excessive inflammatory response and early death. Proc. Natl. Acad. Sci. USA 90:770-774.
23. Lazdins, J. K., T. Klimkait, E. Alteri, M. Walker, K. Woods-Cook, D. Cox, and G. Bilbe. 1991. TGF-β: upregulator of HIV replication in macrophages. Res. Virol. 142:239-242.
24. Lazdins, J. K., T. Klimkait, K. Woods-Cook, M. Walker, E. Alteri, D. Cox, and N. Cerletti. 1991. In vitro effect of transforming growth factor-β on progression of HIV-1 infection in primary mononuclear phagocytes. J. Immunol. 147:1201-1207.
25. Letterio, J. J., A. G. Geiser, A. B. Kulkarni, N. S. Roche, M. B. Sporn, and A. B. Roberts. 1994. Maternal rescue of transforming growth factor-β1 null mice. Science 264:1936-1938.
26. INK4B through an Sp1 consensus site. J. Biol. Chem. 270:26750-26753.
27. Lyons, R. M., and H. L. Moses. 1990. Transforming growth factors and the regulation of cell proliferation. Eur. J. Biochem. 187:467-473.
28. Massague, J. 1990. The transforming growth factor-β family. Annu. Rev. Cell Biol. 6:597-641.
29. Miyamoto, S., P. J. Chiao, and I. M. Verma. 1994. Enhanced IκB alpha degradation is responsible for constitutive NF-κB activity in mature murine B-cell lines. Mol. Cell. Biol. 14:3276-3282.
30. Miyamoto, S., M. Maki, M. J. Schmitt, M. Hatanaka, and I. M. Verma. 1994. Tumor necrosis factorα-induced phosphorylation of IκBα is a signal for its degradation but not dissociation from NF-κB. Proc. Natl. Acad. Sci. USA 91:12740-12744.
31. Miyamoto, S., and I. M. Verma. 1995. Rel/NF-κB/IκB story. Adv. Cancer Res. 66:255-292.
32. Palombella, V. J., O. J. Rando, A. L. Goldberg, and T. Maniatis. 1994. The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB. Cell 78:773-785.
33. Perkins, N. D., L. K. Felzien, J. C. Betts, K. Leung, D. H. Beach, and G. J. Nabel. 1997. Regulation of NF-κB by cyclin-dependent kinases associated with the p300 coactivator. Science 275:523-527.
34. Plevy, S. E., J. H. Gemberling, S. Hsu, A. J. Dorner, and S. T. Smale. 1997. Multiple control elements mediate activation of the murine and human interleukin 12 p40 promoters: evidence of functional synergy between C/ EBP and Rel proteins. Mol. Cell. Biol. 17:4572-4588.
35. Ristow, H. J. 1986. BSC-1 growth inhibitor/type beta transforming growth factor is a strong inhibitor of thymocyte proliferation. Proc. Natl. Acad. Sci. USA 83:5531-5533.
36. Roberts, A. B. and M. B. Sporn. 1990. The transforming growth factor-β, p. 419-472. In M. B. Sporn and A. B. Roberts (ed.), Handbook of experimental pharmacology, peptide growth factors and their receptors. Springer, Heidelberg, Germany.
37. Rook, A. H., J. H. Kehrl, L. M. Wakefield, A. B. Roberts, M. B. Sporn, D. B. Burlington, H. C. Lane, and A. S. Fauci. 1986. Effects of transforming growth factor-β on the functions of natural killer cells: depressed cytolytic activity and blunting of interferon responsiveness. J. Immunol. 136:3916-3920.
38. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
39. Schmitz, M. L. and P. A. Baeuerle. 1991. The p65 subunit is responsible for the strong transcription activating potential of NF-κB. EMBO J. 10:3805-3817.
40. Schreck, R., B. Meier, D. N. Mannel, W. Droge, and P. A. Baeuerle. 1992. Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells. J. Exp. Med. 175:1181-1194.
41. Shukla, R. R., A. Kumar, and P. L. Kimmel. 1993. Transforming growth factor beta increases the expression of HIV-1 gene in transfected human mesangial cells. Kidney Int. 44:1022-1029.
42. Shull, M. M., I. Ormbsy, A. B. Kier, S. Pawlowski, R. J. Diebold, M. Yin, R. Allen, C. Sidman, G. Proetzel, D. Calvin, et al. 1992. Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease. Nature 359:693-699.
43. Sporn, M. B., and A. B. Roberts. 1992. Transforming growth factor-beta: recent progress and new challenges. J. Cell Biol. 119:1017-1021.
44. Tsunawaki, S., M. Sporn, A. Ding, and C. Nathan. 1988. Deactivation of macrophages by transforming growth factor-β. Nature 334:260-262.
45. Van Antwerp, D. J., S. J. Martin, T. Kafri, D. R. Green, and I. M. Berma. 1996. Suppression of TNF-α-induced apoptosis by NF-κB. Science 274:787-789.
46. Wahl, S. M., J. B. Allen, N. McCartney-Francis, M. C. Morganti-Kossmann, T. Kossmann, L. Ellingsworth, U. E. Mai, S. E. Mergenhagen, and J. M. Orenstein. 1991. Macrophage-and astrocyte-derived transforming growth factor beta as a mediator of central nervous system dysfunction in acquired immune deficiency syndrome. J. Exp. Med. 173:981-991.
47. Wang, C. Y., M. W. Mayo, and A. S. Baldwin, Jr.. 1996. TNF-α and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 274:784-787.
48. Wrann, M., S. Bodmer, R. de Martin, C. Siepl, R. Hofer-Warbinek, K. Frei, and E. Hofer. 1987. T cell suppressor factor from human gliohlastoma cells is a 12.5 kd protein closely related to transforming growth factor-beta. EMBO J. 6:1633-1636.
49. Wu, R.-L., T.-T. Chen, and T.-T. Sun. 1994. Functional importance of an Sp1-and an NFκB-related nuclear protein in a keratinocyte-specific promoter of rabbit K3 deratin gene. J. Biol. Chem. 269:28450-28459.
50. Zhong, H., H. SuYang, H. Erdjument-Bromage, P. Tempst, and S. Ghosh. 1997. The transcriptional activity of NF-κB is regulated by the IκB-associated PKAc subunit through a cyclic AMP-independent mechanism. Cell 89:413-424.