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Volumn 53, Issue 1, 1998, Pages 97-104

Exposure of human vascular smooth muscle cells to Raf-1 antisense oligodeoxynucleotides': Cellular responses and pharmacodynamic implications

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CGP 69846A; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; RAF PROTEIN; UNCLASSIFIED DRUG;

EID: 0031913358     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.53.1.97     Document Type: Article
Times cited : (8)

References (35)
  • 1
    • 0027092897 scopus 로고
    • Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides
    • Bennett CF, Chiang M-Y, Chan H, Shoemaker JEE, and Mirabelli CK (1992) Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides. Mol Pharmacol 41:1023-1033.
    • (1992) Mol Pharmacol , vol.41 , pp. 1023-1033
    • Bennett, C.F.1    Chiang, M.-Y.2    Chan, H.3    Shoemaker, J.E.E.4    Mirabelli, C.K.5
  • 2
    • 0028839220 scopus 로고
    • Hypertrophic agonists stimulate the activities of the protein kinases c-Raf and A-Raf in cultured ventricular myocytes
    • Bogoyevitch MA, Marshall CJ, and Sugden PH (1995) Hypertrophic agonists stimulate the activities of the protein kinases c-Raf and A-Raf in cultured ventricular myocytes. J Biol Chem 270:26303-26310.
    • (1995) J Biol Chem , vol.270 , pp. 26303-26310
    • Bogoyevitch, M.A.1    Marshall, C.J.2    Sugden, P.H.3
  • 3
    • 0030889954 scopus 로고    scopus 로고
    • Selective inhibition of A-Raf and C-Raf mRNA expression by antisense oligodeoxynucleotides in rat vascular smooth muscle cells: Role of A-Raf and C-Raf in serum-induced proliferation
    • Cioffi CL, Garay M, Johnston JF, McGraw K, Boggs RT, Hreniuk D, and Monia BP (1997) Selective inhibition of A-Raf and C-Raf mRNA expression by antisense oligodeoxynucleotides in rat vascular smooth muscle cells: role of A-Raf and C-Raf in serum-induced proliferation. Mol Pharmacol 51:383-389.
    • (1997) Mol Pharmacol , vol.51 , pp. 383-389
    • Cioffi, C.L.1    Garay, M.2    Johnston, J.F.3    McGraw, K.4    Boggs, R.T.5    Hreniuk, D.6    Monia, B.P.7
  • 4
    • 0028939172 scopus 로고
    • Pathogenesis of atherosclerosis
    • Consigny MP (1995) Pathogenesis of atherosclerosis. Am J Roentgenol 164:553-558.
    • (1995) Am J Roentgenol , vol.164 , pp. 553-558
    • Consigny, M.P.1
  • 5
    • 0029619816 scopus 로고
    • Kinetic characteristics of Escherichia coli RNAse H1: Cleavage of various antisense oligonucleotide-RNA duplexes
    • Crooke ST, Lemonidis KM, Neilson L, Griffey R, Lesnik EA, and Monia BP (1995) Kinetic characteristics of Escherichia coli RNAse H1: cleavage of various antisense oligonucleotide-RNA duplexes. Biochem J 312:599-608.
    • (1995) Biochem J , vol.312 , pp. 599-608
    • Crooke, S.T.1    Lemonidis, K.M.2    Neilson, L.3    Griffey, R.4    Lesnik, E.A.5    Monia, B.P.6
  • 7
    • 0027165150 scopus 로고
    • The mitogen-activated protein kinase signal transduction pathway
    • Davis DJ (1993) The mitogen-activated protein kinase signal transduction pathway. J Biol Chem 268:14553-14556.
    • (1993) J Biol Chem , vol.268 , pp. 14553-14556
    • Davis, D.J.1
  • 8
    • 0028300301 scopus 로고
    • The emerging concept of vascular remodeling
    • Gibbons GH and Dzau VJ (1994) The emerging concept of vascular remodeling. N Engl J Med 330:1431-1438.
    • (1994) N Engl J Med , vol.330 , pp. 1431-1438
    • Gibbons, G.H.1    Dzau, V.J.2
  • 9
    • 0029067801 scopus 로고
    • Pathophysiology of reocclusion and restenosis
    • Haudenschild CC (1995) Pathophysiology of reocclusion and restenosis. Fibrinolysis 9:44-47.
    • (1995) Fibrinolysis , vol.9 , pp. 44-47
    • Haudenschild, C.C.1
  • 10
    • 0028031527 scopus 로고
    • The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras
    • Jaiswal RK, Moodie SA, Wolfman A, and Landreth GE (1994) The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras. Mol Cell Biol 14:6944-6953.
    • (1994) Mol Cell Biol , vol.14 , pp. 6944-6953
    • Jaiswal, R.K.1    Moodie, S.A.2    Wolfman, A.3    Landreth, G.E.4
  • 11
    • 0025979335 scopus 로고
    • Raf-1 protein kinase is required for growth of induced NIH/3T3 cells
    • Kolch W, Heidecker G, Lloyd P, and Rapp UR (1991) Raf-1 protein kinase is required for growth of induced NIH/3T3 cells. Nature (Lond) 349:426-428.
    • (1991) Nature (Lond) , vol.349 , pp. 426-428
    • Kolch, W.1    Heidecker, G.2    Lloyd, P.3    Rapp, U.R.4
  • 13
    • 0028272507 scopus 로고
    • Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
    • Leevers SJ, Paterson HF, and Marshall CJ (1994) Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature (Lond) 369:411-414.
    • (1994) Nature (Lond) , vol.369 , pp. 411-414
    • Leevers, S.J.1    Paterson, H.F.2    Marshall, C.J.3
  • 14
    • 0029911804 scopus 로고    scopus 로고
    • Activation of Mil/Raf protein kinases in mitotic cells
    • Lovric J and Moelling K (1996) Activation of Mil/Raf protein kinases in mitotic cells. Oncogene 12:1109-1116.
    • (1996) Oncogene , vol.12 , pp. 1109-1116
    • Lovric, J.1    Moelling, K.2
  • 15
    • 0028152333 scopus 로고
    • MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
    • Marshall CJ (1994) MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr Opin Gen Dev 4:82-89.
    • (1994) Curr Opin Gen Dev , vol.4 , pp. 82-89
    • Marshall, C.J.1
  • 17
    • 0029977448 scopus 로고    scopus 로고
    • Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
    • Monia BP, Johnston JF, Geiger T, Muller M, and Fabbro D (1996a) Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. Nat Med 2:668-675.
    • (1996) Nat Med , vol.2 , pp. 668-675
    • Monia, B.P.1    Johnston, J.F.2    Geiger, T.3    Muller, M.4    Fabbro, D.5
  • 19
    • 12644268252 scopus 로고    scopus 로고
    • Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo
    • Monia BP, Sasmor H, Johnston JF, Freier SM, Lesnik EA, Muller M, Geiger T, Altmann K-H, Moser H, and Fabbro D (1996b) Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo. Proc Natl Acad Sci USA 93:15481-15484.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 15481-15484
    • Monia, B.P.1    Sasmor, H.2    Johnston, J.F.3    Freier, S.M.4    Lesnik, E.A.5    Muller, M.6    Geiger, T.7    Altmann, K.-H.8    Moser, H.9    Fabbro, D.10
  • 20
    • 0027323303 scopus 로고
    • Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia
    • Morishito R, Gibbons GH, Ellison KE, Nakajima M, Zhang L, Kaneda Y, Ogihara T, and Dzau VJ (1993) Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia. Proc Natl Acad Sci USA 90:8474-8478.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8474-8478
    • Morishito, R.1    Gibbons, G.H.2    Ellison, K.E.3    Nakajima, M.4    Zhang, L.5    Kaneda, Y.6    Ogihara, T.7    Dzau, V.J.8
  • 24
    • 0029795987 scopus 로고    scopus 로고
    • Treatment of vascular smooth muscle cells with antisense phophorothioate oligode-oxynucleotides directed against p42 and p44 mitogen-activated protein kinases abolishes DNA synthesis in response to platelet-derived growth factor
    • Robinson CJM, Scott PH, Allan AB, Jess T, Gould GW, and Plevin R (1996) Treatment of vascular smooth muscle cells with antisense phophorothioate oligode-oxynucleotides directed against p42 and p44 mitogen-activated protein kinases abolishes DNA synthesis in response to platelet-derived growth factor. Biochem J 320:123-127.
    • (1996) Biochem J , vol.320 , pp. 123-127
    • Robinson, C.J.M.1    Scott, P.H.2    Allan, A.B.3    Jess, T.4    Gould, G.W.5    Plevin, R.6
  • 25
    • 0028970042 scopus 로고
    • Cell biology of atherosclerosis
    • Ross R (1995) Cell biology of atherosclerosis. Annu Rev Physiol 57:791-804.
    • (1995) Annu Rev Physiol , vol.57 , pp. 791-804
    • Ross, R.1
  • 26
    • 0029098078 scopus 로고
    • The intima: Soil for atherosclerosis and restenosis
    • Schwartz SM, deBlois D, and O'Brien ERM (1995) The intima: soil for atherosclerosis and restenosis. Circ Res 77:445-465.
    • (1995) Circ Res , vol.77 , pp. 445-465
    • Schwartz, S.M.1    DeBlois, D.2    O'Brien, E.R.M.3
  • 27
    • 0027293123 scopus 로고
    • Downregulation of c-myc expression by antisense oligonucleotides inhibits proliferation of human smooth muscle cells
    • Shi Y, Hutchinson HG, Hall DJ, and Zalewski A (1994) Downregulation of c-myc expression by antisense oligonucleotides inhibits proliferation of human smooth muscle cells. Circulation 90:1190-1195.
    • (1994) Circulation , vol.90 , pp. 1190-1195
    • Shi, Y.1    Hutchinson, H.G.2    Hall, D.J.3    Zalewski, A.4
  • 28
    • 0026641052 scopus 로고
    • Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo
    • Simons M, Edelman ER, DeKeyser J-L, Langer R, and Rosenberg RD (1992) Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo. Nature (Lond) 359:67-70.
    • (1992) Nature (Lond) , vol.359 , pp. 67-70
    • Simons, M.1    Edelman, E.R.2    DeKeyser, J.-L.3    Langer, R.4    Rosenberg, R.D.5
  • 29
    • 0025266334 scopus 로고
    • Expression of raf family protooncogenes in normal tissues
    • Storm SM, Cleveland JL, and Rapp UR (1990) Expression of raf family protooncogenes in normal tissues. Oncogene 5:345-351.
    • (1990) Oncogene , vol.5 , pp. 345-351
    • Storm, S.M.1    Cleveland, J.L.2    Rapp, U.R.3
  • 30
    • 0028089986 scopus 로고
    • Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1
    • Sun H, Tonks NK, and Bar-Sagi D (1994) Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1. Science (Washington D C) 266:285-288.
    • (1994) Science (Washington D C) , vol.266 , pp. 285-288
    • Sun, H.1    Tonks, N.K.2    Bar-Sagi, D.3
  • 31
    • 0030586470 scopus 로고    scopus 로고
    • Death by decapitation for mRNA
    • Tuite MF (1996) Death by decapitation for mRNA. Nature (Lond) 382:577-579.
    • (1996) Nature (Lond) , vol.382 , pp. 577-579
    • Tuite, M.F.1
  • 34
    • 0030062094 scopus 로고    scopus 로고
    • Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated HeLa cells
    • Wu X, Noh SJ, Zhou G, Dixon JE, and Guan K-L (1996) Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated HeLa cells. J Biol Chem 271:3265-3271.
    • (1996) J Biol Chem , vol.271 , pp. 3265-3271
    • Wu, X.1    Noh, S.J.2    Zhou, G.3    Dixon, J.E.4    Guan, K.-L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.