ACAT inhibitors: Evolution from cholesterol-absorption inhibitors to antiatherosclerotic agents

Drug Discovery Today

Volumn 3, Issue 1, 1998, Pages 19-25

  Roth, Bruce D ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2,6 DIISOPROPYL) 3 [[1 [4 (DIMETHYLAMINO)PHENYL]CYCLOPENTYL]METHYL]UREA; 1 BENZYL 1 [[3 (4 CHLOROPHENYL) 5 METHYL 2 BENZOFURANYL]METHYL] 3 (2,4,6 TRIFLUOROPHENYL)UREA; 2 [5 (3,5 DIMETHYL 1 PYRAZOLYL)PENTYLSULFINYL] 4,5 DIPHENYLIMIDAZOLE; 3 (2,4 DIFLUOROPHENYL) 1 HEPTYL 1 (4 NEOPENTYLBENZYL)UREA; 3 DECYLDIMETHYLSILYL N [2 (4 METHYLPHENYL) 1 PHENYLETHYL]PROPIONAMIDE; C 1976; CHOLESTEROL ACYLTRANSFERASE INHIBITOR; CHOLESTEROL ESTER; COLESTYRAMINE; CP 113818; HIGH DENSITY LIPOPROTEIN; HYPOCHOLESTEROLEMIC AGENT; LOW DENSITY LIPOPROTEIN; MELINAMIDE; NICOTINIC ACID; SAH 57118; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADRENAL CORTEX; ADRENAL DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DRUG DEVELOPMENT; DRUG EFFICACY; DRUG INDICATION; GUINEA PIG; HUMAN; HUMAN TISSUE; HYPERCHOLESTEROLEMIA; MOUSE; NONHUMAN; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; RABBIT; RAT; REVIEW;

EID: 0031911857     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(97)01123-9     Document Type: Review

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