Inhibitors of acyl-CoA: Cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. The synthesis and biological activity of a series of malonester amides

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 6, 1996, Pages 713-718

  Sliskovic, D R ^b   Picard, J A ^b   Roark, W H ^b   Essenburg, A D ^a   Krause, B R ^a   Minton, L L ^a   Reindel, J F ^a   Stanfield, R L ^b  

^a PFIZER INC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANILIDE; ANTILIPEMIC AGENT; CHOLESTEROL ACYLTRANSFERASE INHIBITOR; FATTY ACID ESTER DERIVATIVE; MALONAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ANOREXIA; ARTERY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME INHIBITION; GUINEA PIG; HYPERCHOLESTEROLEMIA; INTESTINE; MACROPHAGE; MICROSOME; NONHUMAN; ORAL DRUG ADMINISTRATION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RABBIT; RAT;

ANIMALIA; CAVIA PORCELLUS; ORYCTOLAGUS CUNICULUS; RODENTIA; SUS SCROFA;

EID: 0029872404     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00098-4     Document Type: Article

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