Regulation of K+ and Ca++ channels by a family of neuropeptide Y receptors

Journal of Pharmacology and Experimental Therapeutics

Volumn 284, Issue 2, 1998, Pages 625-632

  Sun, Lihjen ^a   Philipson, Louis H ^a   Miller, Richard J ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; GR 231118; N [1 [4 [[[[4 [(DIMETHYLAMINO)METHYL]CYCLOHEXYL]METHYL]AMINO]IMINOMETHYL]BENZYL] 2 OXO 2 (1 PYRROLIDINYL)ETHYL] ALPHA [(2 NAPHTHALENYLSULFONYL)AMINO]BENZENEPROPANAMIDE; NALPHA (DIPHENYLACETYL) N (4 HYDROXYBENZYL) DEXTRO ARGININAMIDE; NEUROPEPTIDE Y; NEUROPEPTIDE Y [13-36]; NEUROPEPTIDE Y [31 LEUCINE 34 PROLINE]; NEUROPEPTIDE Y DERIVATIVE; NEUROPEPTIDE Y RECEPTOR; PANCREAS POLYPEPTIDE; PEPTIDE YY; PERTUSSIS TOXIN; POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; NERVE CELL EXCITABILITY; NONHUMAN; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; XENOPUS;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CELL LINE; ELECTRIC CONDUCTIVITY; HUMANS; ION CHANNEL GATING; MEMBRANE POTENTIALS; NEUROPEPTIDE Y; PEPTIDE YY; POTASSIUM CHANNELS; RECEPTORS, NEUROPEPTIDE Y; RECOMBINANT PROTEINS; XENOPUS LAEVIS;

EID: 0031909501     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. Audersson S, Davis DL, Dahlback H, Jornvall H and Russell DW (1989) Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J Biol Chem 264:8222-8229.
2. Bard JA, Walker MW, Branchek TA and Weinshank RL (1995) Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y and peptide YY. J Biol Chem 270:26762-26765.
3. Bitran M, Daniels AJ and Boric MP (1997) GW 1229, a novel Neuropeptide Y Y1 receptor antagonist, inhibits the vasoconstriction effect of neuropeptide Y in the hamster microcirculation. Eur J Pharmacol 319:43-47.
4. Bourinet E, Soong TW, Stea A and Snutch TP (1996) Determinants of the G-protein dependent opioid modulation of neuronal calcium channels. Proc Natl Acad Sci USA 93:1486-1491.
5. + channels (GIRK1) by human NPY1 receptors. Br J Pharmacol 116:2346-2348.
6. Chen G and van den Pol AN (1996) Multiple NPY receptors coexist in pre and postsynaptic sites: inhibition of GABA release in isolated self innervating SCN neurons. J Neurosci 16:7711-7724.
7. Colmers WF and Wahlestedt C (1993) The Biology of Neuropeptide Y and Related Peptides. Humana Press, Totowa, NJ.
8. Colmers WF and Bleakman D (1994) Effects of neuropeptide Y on the electrical properties of neurons. Trends Neurosci 17:373-379.
9. De Waard M, Liu H, Walker D, Scott VES, Gurnett CA and Campbell KP (1997) Direct binding of G-protein β/γ complex to voltage dependent calcium channels. Nature 385:442-446.
10. Doods HN, Wienen W, Entzeroth M, Rudolf K, Eberlein W, Engel W, and Weiland HA (1995) Pharmacological characterization of the selective nonpeptide neuropeptide Y Y1 receptor antagonist BIBP3226. J Pharmacol Exp Ther 275:136-142.
11. + channel activity of neuronal ad cardiac G-protein-activated inward rectifiers. Biochem Biophys Res Commun 212:657-663.
12. Erickson JC, Clegg KE and Palmiter RD (1996) Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 381:415-418.
13. o induced coupling of NPY receptors to calcium channels in sensory neurons. Proc Natl Acad Sci USA 85:3633-3637.
14. Foucart S, Bleakman D, Bindokas VP and Miller RJ (1993) Neuropeptide Y and pancreatic polypeptide reduce calcium currents in acutely dissociated neurons from adult rat superior cervical ganglia. J Pharmacol Exp Ther 265:903-909.
15. 34J-Peptide YY, is also a high affinity radioligand for human pancreatic polypeptide I receptors. Eur J Pharmacol 318:485-490.
16. Gehlert DR and Gackenheimer SL (1997) Differential distribution of neuropeptide Y Y1 and Y2 receptors in rat and guinea pig brains. Neuroscience 76:215-224.
17. Gerald C, Walker MW, Vaysse PJJ, He C, Branchek TA and Weinshank RL (1995) Expression cloning and pharmacological characterization of a human hippocampal neuropeptide Y/Peptide YY Y2 receptor subtype. J Biol Chem 270:26758-26761.
18. Gerald C, Walker MW, Criscione BH, Smith KE, Vaysse P, Durkin MM, Laz TM, Linemeyer DL, Shaffhauser AO, Whitebread S, Hofbauer KG, Taber RI, Branchek TA and Weinshank RL (1996) A receptor subtype involved in neuropeptide Y induced food intake. Nature 382:156-159.
19. Glaum SR, Kara M, Bindokas VP, Lee CC, Polonsky KS, Bell GI and Miller RJ (1996) Leptin, the obese gene product rapidly modulates synaptic transmission in the hypothalamus. Mol Pharmacol 50:230-235.
20. Gregor P, Feng Y, DeCarr LB, Cornfield LJ and McCaleb ML (1996) Molecular characterization of a second mouse pancreatic polypeptide receptor and its inactivated human homologue. J Biol Chem 44:27776-27781.
21. Grundemar L, Wahlestedt C and Reis DJ (1991) Long lasting inhibition of the cardiovascular responses to glutamate and the baroreceptor reflex elicited by neuropeptide Y injected into the nucleus of the solitary tract. Neurosci Lett 122:135-139.
22. Herzog H, Hort YJ, Ball HJ, Hayes G, Shine J and Selbie LA (1992) Cloned human Neuropeptide Y receptor couples to two different second messenger systems. Proc Natl Acad Sci USA 89:5794-5798.
23. Hille B (1994) Modulation of ion channels by G-protein coupled receptor. Trends Neurosci 17:531-535.
24. Hirning LD, Thayer SA, Miller RJ, Fox AP, McCleskey EW, Olivera B and Tsien RW (1988) Dominant role of N type calcium channels in evoked release of norepinephrine from rat sympathetic neurons. Science 239:57-61.
25. + channel is important for channel activation. Neuron 15:1133-1143.
26. Huhman K and Albers H (1994) Neuropeptide Y microinjected into the suprchiasmatic region phase shifts circadian rhythms in constant darkness. Peptides 8:1475-,.
27. Ikeda S (1996) Voltage dependent modulation of N type calcium channels by G-protein β/γ subunits. Nature 380:255-258.
28. Jurman ME, Boland LM, Liu Y and Yellen G (1994) Visual identification of individual transfected cells for electrophysiology using antibody-coated beads. Biotechniques 17:876-881.
29. Kalra SP and Kalra PS (1996) Is neuropeptide Y a naturally occurring appetite transducer? Curr Opin Endocrinol Diabetes 3:157-163.
30. + channel proteins. Nature 374:135-141.
31. Larhammer D (1996) Evolution of neuropeptide Y, peptide YY and pancreatic polypeptide. Regul Pept 62:1-11.
32. + channel by a G protein-linked mechanism: Coexpression in Xenopus oocytes. Mol Pharmacol 47:1035-1040.
33. 32]-NPY on monoamine and metabolite levels in dialysates from rat hypothalamus during feeding behaviour. Neuropeptides 30:391-398.
34. 2+ currents and reduce transient calcium increases in rat dentate granule cells. J Neurosci 166:1422-1429.
35. Miller RJ (1990) The receptor mediated regulation of calcium channels and neurotransmitter release. FASEB J 4:3291-3300.
36. Miller RJ and Bell GI (1996) JAK/STAT eats the fat. Trends Neurosci 19:159-161.
37. Obrietan K and van den Pol AN (1996) Neuropeptide Y depresses GABA mediated calcium transients in developing suprachiasmatic neurons: A novel form of long term depression. J Neurosci 16:3521-3533.
38. 0-type protein of Xenopus laevis oocytes. FEBS Lett 244:188-192.
39. Olate J, Martinez S, Purcell P, Jorquera H, Codina J, Birnbaumer L and Allende JE (1990) Molecular cloning and sequence determination of four different cDNA species coding for α-subunits of G proteins from Xenopus laevis oocytes. FEBS Lett 268:27-31.
40. Page KM, Stephens GJ, Berrow NS and Dolphin AC (1997) The intracellular loop between domains I and 2 of the B type calcium channel confers aspects of G-protein sensitivity to the E-type calcium channel. J Neurosci 17:1330-1338.
41. Philipson LH, Hice RE, Schaefer K, LaMendola J, Bell GI, Nelson DJ and Steiner DF (1991) Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel. Proc Natl Acad Sci USA 88:53-57.
42. Rhim H, Kinney GA, Emmerson PJ and Miller RJ (1997) Regulation of neurotransmission in the arcuate nucleus of the rat by different neuropeptide Y receptors. J Neurosci 17:2980-2989.
43. Rimland JM, Seward EP, Humbert Y, Ratti W, Trist DG and North RA (1996) Coexpression with potassium channel subunits used to clone the Y2 receptor for neuropeptide Y. Mol Pharmacol 49:387-390.
44. Schild HO (1947) pA, a new scale for the measurement of drug antagonism. Br J Pharmacol 2:189-206.
45. Schild HO (1949) pAx and competitive drug antagonism. Br J Pharmacol 4:277-280.
46. 2+ influx by a G-protein linked adenosine receptor at hippocampal synapses. Neuron 8:1139-1150.
47. + channel by G-protein α-subunits. Nature 380:624-627.
48. Serradeil-Le Gal C, Valette G, Rouby PE, Pellet A, Oury-Donat F, Brossard G, Lespy L, Marty E, Neliat G, Cointet P, Maffrand JP and Le Fur G (1995) SR 120819A, an orally active and selective neuropeptide Y Y1 receptor antagonist. FEBS Lett 62:192-196.
49. Shekter LR, Taussig R, Gillard S and Miller RJ (1997) Regulation of human neuronal calcium channels by G-protein β/γ subunits. Mol Pharmacol 52:282-291.
50. + channel GIRK2. Proc Natl Acad Sci USA 94:923-927.
51. Silinsky EM (1985) The biophysical pharmacology of calcium-dependent acetylcholine secretion. Pharmacol Rev 37:81-132.
52. Stanley BG, Magdalin W, Seirafi A, Nguyen MM and Leibowitz SF (1992) Evidence for neuropeptide Y mediation of eating produced by food deprivation and for a variant of the Y1 receptor mediating this peptide's effects. Peptides 13:581-586.
53. Stanley BG (1993) Neuropeptide Y in multiple hypothalamic sites controls eating behaviour, endocrine and autonomie systems for body energy balance, in The Biology of Neuropeptide Y and Related Peptides (Colmers WF and Wahlestedt C eds) pp 457-509, Humana, Totowa, NJ.
54. 2+ influx at sympathetic nerve terminals. Nature 364:635-639.
55. 2+ channels. J Neurosci 16:4617-4624.
56. + channel. FEBS Lett 379:31-37.
57. 1E calcium channel subtypes. J Biol Chem 269:22347-22357.
58. Wollmuth LP, Shapiro MS and Hille B (1995) Pancreatic polypeptide inhibits calcium channels in rat sympathetic neurons via two signaling pathways. J Neurophysiol 73:1323-1328.
59. 2+ channels support their inhibition by G-proteins. Neuron 17:991-1003.
60. + channels in C cells of amphibian sympathetic ganglia. Neurotci Lett 117:123-128.