Neuropeptide Y1 receptors inhibit N-type calcium currents and reduce transient calcium increases in rat dentate granule cells

Journal of Neuroscience

Volumn 16, Issue 4, 1996, Pages 1422-1429

  McQuiston, A Rory ^a,c   Petrozzino, Jeffrey J ^b   Connor, John A ^b   Colmers, William F ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b HOFFMANN LA ROCHE INC   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

acutely dissociated neurons; dentate gyrus granule cell; intracellular calcium imaging; neuropeptide Y; voltage dependent calcium current; Y1 receptor

Indexed keywords

BARIUM ION; CALCIUM CHANNEL; CALCIUM ION; DYNORPHIN; NEUROPEPTIDE Y RECEPTOR; NIMODIPINE; OMEGA CONOTOXIN GVIA; OPIATE PEPTIDE; CALCIUM; NEUROPEPTIDE RECEPTOR; NEUROPEPTIDE Y;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CALCIUM TRANSPORT; CONTROLLED STUDY; DENTATE GYRUS; GRANULE CELL; HIPPOCAMPUS; MALE; MEMBRANE DEPOLARIZATION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; ANIMAL; DRUG EFFECT; METABOLISM; SPRAGUE DAWLEY RAT; TIME;

ANIMALS; CALCIUM; CALCIUM CHANNELS; DENTATE GYRUS; MALE; NEUROPEPTIDE Y; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROPEPTIDE; TIME FACTORS;

EID: 0029664675     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-04-01422.1996     Document Type: Article

References (54)

1. Aicher SA, Springton M, Berger SB, Reis DJ, Wahlestedt C (1991) Receptor-selective analogs demonstrate NPY/PYY receptor heterogeneity in rat brain. Neurosci Lett 130:32-36.
2. Bean BP (1989) Neurotransmitter inhibition of neuronal calcium currents by changes in channel voltage dependence. Nature 340:153-156.
3. 2+ current and M current in rat sympathetic neurons. Proc Natl Acad Sci USA 88:652-656.
4. Beech DJ, Bernheim L, Hille B (1992) Pertussis toxin and voltage dependence distinguish multiple pathways modulating calcium channels in rat sympathetic neurons. Neuron 8:97-106.
5. Blanton MG, Lo Turco JJ, Kriegstein AR (1989) Whole cell recording from neurons in slices of reptilian and mammalian cerebral cortex. J Neurosci Methods 30:203-210.
6. 2 receptor. Br J Pharmacol 103:1781-1789.
7. Bleakman D, Harrison NL, Colmers WF, Miller RJ (1992) Investigations into neuropeptide Y-mediated presynaptic inhibition in cultured hippocampal neurones of the rat. Br J Pharmacol 107:334-340.
8. Bleakman D, Miller RJ, Colmers WF (1993) Actions of neuropeptide Y on the electrophysiological properties of nerve cells. In: The biology of neuropeptide Y and related peptides (Colmers WF, Wahlestedt C, eds), pp 241-272. Totowa, NJ: Humana.
9. Brooks PA, Kelly JS, Allen JM, Smith DAS, Stone TW (1987) Direct excitatory effects of neuropeptide Y (NPY) in rat hippocampal neurones in vitro. Brain Res 408:295-298.
10. Colmers WF, Bleakman D (1994) Effects of neuropeptide Y on the electrical properties of neurons. Trends Neurosci 17:373-379.
11. Colmers WF, Lukowiak K, Pittman QJ (1987) Presynaptic action of neuropeptide Y in area CA1 of the rat hippocampal slice. J Physiol (Lond) 383:285-299.
12. Colmers WF, Lukowiak K, Pittman QJ (1988) Neuropeptide Y action in the rat hippocampal slice: site and mechanism of presynaptic inhibition. J Neurosci 8:3827-3837.
13. Connor JA (1986) Digital imaging of free calcium changes and of spatial gradients in growing processes in single, mammalian central nervous system cells. Proc Natl Acad Sci USA 83:6179-6183.
14. Diversé-Pierluissi M, Goldsmith PK, Dunlap K (1995) Transmitter-mediated inhibition of N-type calcium channels in sensory neurons involves multiple GTP binding proteins and subunits. Neuron 14:191-200.
15. Drake CT, Terman GW, Simmons ML, Milner TA, Kunkel DD, Schwartzkroin PA, Chavkin C (1994) Dynorphin opioids present in dentate granule cells may function as retrograde inhibitory transmitters. J Neurosci 14:3736-3750.
16. 2 receptors in the rat brain. Eur J Pharmacol 191:501-503.
17. Dumont Y, Martel J-C, Fournier A, St-Pierre S, Quirion R (1992) Neuropeptide Y and neuropeptide Y receptor subtypes in brain and peripheral tissues. Prog Neurobiol 38:125-167.
18. Dumont Y, Fournier A, St-Pierre S, Quirion R (1993) Comparative characterization and autoradiographic distribution of neuropeptide Y receptor subtypes in the rat brain. J Neurosci 13:73-86.
19. Eliot LS, Johnston D (1994) Multiple components of calcium current in acutely dissociated dentate gyrus granule neurons. J Neurophysiol 72:762-777.
20. Formenti A, Arrigoni E, Mancia M (1993) Two distinct modulatory effects on calcium channels in adult rat sensory neurons. Biophys J 64:1029-1037.
21. Foucart S, Bleakman D, Bindokas VP, Miller RJ (1993) Neuropeptide Y and pancreatic polypeptide reduce calcium currents in acutely dissociated neurons from adult rat superior cervical ganglia. J Pharmacol Exp Ther 265:903-909.
22. Ghosh A, Ginty DD, Bading H, Greenberg ME (1994) Calcium regulation of gene expression in neuronal cells. J Neurobiol 25:294-303.
23. Goodman JH, Sloviter RS (1993) Cocaine neurotoxicity and altered neuropeptide Y immunoreactivity in the rat hippocampus: a silver degeneration and immunocytochemical study. Brain Res 616:263-272.
24. Grundemar L, Sheikh SP, Wahlestedt C (1993) Characterization of receptor types for neuropeptide Y and related peptides. In: The biology of neuropeptide Y and related peptides (Colmers WF, Wahlestedt C, eds), pp 197-239. Totowa, NJ: Humana.
25. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
26. Haas HL, Hermann A, Greene RW, Chan-Palay V (1987) Action and location of neuropeptide tyrosine (Y) on hippocampal neurons of the rat in slice preparations. J Comp Neurol 257:208-215.
27. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 391:85-100.
28. Hendry SHC (1993) Organization of neuropeptide Y neurons in the mammalian central nervous system. In: The biology of neuropeptide Y and related peptides (Colmers WF, Wahlestedt C, eds), pp 65-156. Totowa, NJ: Humana.
29. Hille B (1994) Modulation of ion-channel function by G-protein-coupled receptors. Trends Neurosci 17:531-536.
30. Hjorth-Simonsen A, Jeune B (1972) Origin and termination of the hippocampal perforant path in the rat studied by silver impregnation. J Comp Neurol 144:215-232.
31. 2 receptors - the inhibitory effect of noradrenaline in rat locus coeruleus neurones. Naunyn Schmiedebergs Arch Pharmacol 348:546-548.
32. Kay AR (1989) A procedure for isolating neurons from the mature mammalian brain. In: A dissection and tissue culture manual of the nervous system (Shahar A, de Vellis J, Vernadakis A, Haber B, eds), pp 54-59. New York: Liss.
33. Klapstein GJ, Colmers WF (1993) On the sites of presynaptic inhibition by neuropeptide Y in rat hippocampus in vitro. Hippocampus 3:103-112.
34. Laatch RH, Cowan WM (1967) Electron microscopic studies of the dentate gyrus of the rat. II. Degeneration of commissural afferents. J Comp Neurol 130:241-262.
35. Lester RAJ, Jahr CE (1990) Quisqualate receptor-mediated depression of calcium currents in hippocampal neurons. Neuron 4:741-749.
36. Luebke JI, Dunlap K (1994) Sensory neuron N-type calcium currents are inhibited by both voltage-dependent and -independent mechanisms. Pflügers Arch 428:499-507.
37. McQuiston AR, Colmers WF (1992) Neuropeptide Y does not alter NMDA conductances in CA3 pyramidal neurons: a slice-patch study. Neurosci Lett 138:261-264.
38. Michel MC (1991) Receptors for neuropeptide Y: multiple subtypes and multiple second messengers. Trends Pharmacol 12:389-394.
39. Mody I, Salter MW, MacDonald JF (1989) Whole cell voltage-clamp recordings in granule cells acutely isolated from hippocampal slices of adult or aged rats. Neurosci Lett 96:70-75.
40. Morgan JI, Curran T (1986) Role of ion influx in the control of c-fos expression. Nature 322:552-555.
41. Morris BJ, Feasy KJ, Ten Bruggecate G, Herz A, Höllt V (1988) Electrical stimulation in vivo increases the expression of proenkephalin mRNA and decreases the expression of prodynporphin mRNA in rat hippocampal granule cells. Proc Natl Acad Sci USA 85:3226-3230.
42. Murphy TH, Worely PF, Baraban JM (1991) L-type voltage-sensitive calcium channels mediate synaptic activation of immediate early genes. Neuron 7:625-635.
43. Shapiro MS, Wollmuth LP, Hille B (1994) Angiotensin II inhibits calcium and M current channels in rat sympathetic neurons via G proteins. Neuron 12:1319-1329.
44. Simmons ML, Terman GW, Gibbs SM, Chavkin C (1995) L-type calcium channels mediate dynorphin neuropeptide release from dendrites but not axons of hippocampal granule cells. Neuron 14:1265-1272.
45. Sundler F, Bottcher G, Ekblad E, Hakanson R (1993) PP, PYY, and NPY: occurrence and distribution in the periphery. In: The biology of neuropeptide Y and related peptides (Colmers WF, Wahlestedt C, eds), pp 157-196. Totowa, NJ: Humana.
46. Toselli M, Taglietti V (1993) Baclofen inhibits high-threshold calcium currents with two distinct modes in rat hippocampal neurons. Neurosci Lett 164:134-136.
47. Tsien RY (1989) Fluorescent indicators of ion concentrations. Methods Cell Biol 30:127-156.
48. 2+ currents. J Physiol (Lond) 475:185-195.
49. Wahlestedt C, Reis DJ (1993) Neuropeptide Y-related peptides and their receptors - are the receptors potential therapeutic drug targets? Annu Rev Pharmacol Toxicol 33:309-352.
50. + current in the medial entorhinal cortex. Neuron 11:1037-1047.
51. Wiley JW, Gross RA, MacDonald RL (1993) Agonists for neuropeptide Y receptor subtypes NPY-1 and NPY-2 have opposite actions on rat nodose calcium currents. J Neurophysiol 70:324-330.
52. Xiong Z, Bolzon BJ, Cheung DW (1993) Neuropeptide Y potentiates calcium-channel currents in single vascular smooth muscle cells. Pflügers Arch 423:504-510.
53. +-channels in C-cells of amphibian sympathetic ganglia. Neurosci Lett 117:123-128.
54. Zukowska-Grojec Z, Wahlestedt C (1993) Origin and actions of neuropeptide Y in the cardiovascular system. In: The biology of neuropeptide Y and related peptides (Colmers WF, Wahlestedt C, eds), pp 315-388. Totowa, NJ: Humana.