Heterogeneity in E2 region of GBV-C/hepatitis G virus and hepatitis C virus

Journal of Medical Virology

Volumn 55, Issue 2, 1998, Pages 109-117

  Kato, Takanobu ^a   Mizokami, Masashi ^a   Nakano, Tatsunori ^a   Orito, Etsuro ^a   Ohba, Ken Ichi ^a   Kondo, Yutaka ^a   Tanaka, Yasuhito ^a   Ueda, Ryuzo ^a   Mukaide, Motokazu ^b   Fujita, Kaoru ^b   Yasuda, Kiyomi ^c   Iino, Shiro ^d  

^a NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

^b SRL INC   (Japan)

^c Kiyokawa Hospital   (Japan)

^d ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

GBV C; HCV; HGV; Hypervariable; Interferon ; Region; SSCP

Indexed keywords

ALPHA INTERFERON;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GEL ELECTROPHORESIS; GENE AMPLIFICATION; GENETIC HETEROGENEITY; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HEPATITIS G VIRUS; HUMAN; HUMAN TISSUE; MALE; NUCLEOTIDE SEQUENCE; PERSISTENT INFECTION; POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM;

ADULT; AGED; AMINO ACID SEQUENCE; ANTIVIRAL AGENTS; BASE SEQUENCE; DNA, VIRAL; FEMALE; FLAVIVIRIDAE; GENETIC HETEROGENEITY; HEPACIVIRUS; HEPATITIS C; HEPATITIS, VIRAL, HUMAN; HUMANS; INTERFERON-ALPHA; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; VIRAL ENVELOPE PROTEINS;

GB VIRUS C/HEPATITIS G VIRUS; HEPATITIS C VIRUS; RNA VIRUSES;

EID: 0031895013     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9071(199806)55:2<109::AID-JMV5>3.0.CO;2-6     Document Type: Article

References (32)

1. Alter MJ, Gallagher M, Morris TT, Moyer LA, Meeks EL, Krawczynski K, Kim JP, Margolis HS (1997): Acute non-A-E hepatitis in the United States and the role of hepatitis G virus infection. New England Journal of Medicine 336:741-746.
2. Enomoto N, Kurosaki M, Tanaka Y, Marumo F, Sato C (1994): Fluctuation of hepatitis C virus quasispecies in persistent infection and interferon treatment revealed by single-strand conformation polymorphism analysis. Journal of General Virology 75:1361-1369.
3. Enomoto N, Sakuma I, Asahina Y, Kurosaki M, Murakami T, Yamamoto C, Ogura Y, Izumi N, Marumo F, Sato C (1996): Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection. New England Journal of Medicine 334:77-81.
4. Erker JC, Simons JN, Muerhoff AS, Leary TP, Chalmers ML, Desai SM, Mushahwar IK (1996): Molecular cloning and characterization of a GB virus C isolates from a patient with non-A-E hepatitis. Journal of General Virology 77:2713-2720.
5. Gojobori T, Ishii K, Nei M (1982): Estimation of average number of nucleotide substitutions when the rate of substitution varies with nucleotide. Journal of Molecular Evolution 18:414-423.
6. Hijikata M, Mishiro S (1996): Circulating immune complexes that contain HCV but not GBV-C in co-infected hosts. International Hepatology Communications. 5:339-344.
7. Ina Y (1994): ODEN: A program package for molecular evolutionary analysis and database search of DNA and amino acid sequences. Computer Applications in the Biosciences 10:11-12.
8. Kato N, Hijikata M, Ootsuka Y, Nakagawa M, Ohkoshi S, Sugimura T, Shimotohno K (1990): Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B, hepatitis. Proceedings of the National Academy of Sciences USA 87: 9524-9528.
9. Kato N, Ootsuyama Y, Ohkoshi S, Nakazawa T, Sekiya H, Hijikata M, Shimotohno K (1992): Characterization of hypervariable regions in the putative envelope protein of hepatitis C virus. Biochemical Biophysical Research Communications 189:119-127.
10. Kato N, Ootsuyama Y, Sekiya H, Ohkoshi S, Nakazawa T, Hijikata M, Shimotohno K (1994): Genetic drift in hypervariable region 1 of the viral genome in persistent hepatitis C virus infection. Journal of Virology 68:1776-1784.
11. Kato T, Mizokami M, Nakano T, Kondo Y, Ohba K, Onto E, Ueda R, Mukaide M, Gurtsevitch V, Syrtsev A, Ruzbakiev R, Abdurakhnamov M, Yamashita M, Hayami M (1997): High prevalence of GB virus C/hepatitis G virus infection among the Jewish population in Uzbekistan. Virus Research 48:81-87.
12. Leary TP, Muerhoff AS, Simons JN, Pilot-Matias TJ, Erker JC, Chalmers ML, Schlauder GG, Dawson GJ, Desai SM, Mushahwar IK (1996): Sequence and genomic organization of GBV-C: A novel member of the Flaviviridae associated with human non-A-E hepatitis. Journal of Medical Virology 48:60-67.
13. Linnen J, Wages J, Zhang-Keck Z-Y, Fry KE, Krawczynski KZ, Alter H, Koonin E, Gallagher M, Alter MJ, Hadziyannis S, Karayiannis P, Fung K, Nakatsuji Y, Shih JW-K, Young L, Piatak Jr. M, Hoover C, Fernandez J, Chen S, Zoul JC, Morris T, Hyams KC, Ismay S, Lifson JD, Hess G, Foung SKH, Thomas H, Bradley D, Margolis H, Kim JP (1996): Molecular cloning and disease association of hepatitis G virus: A transfusion-transmissible agent. Science 271:505-508.
14. Masuko K, Mitsui T, Iwano K, Yamazaki C, Okuda K, Meguro T, Murayama C, Inoue T, Tsuda F, Okamoto H, Miyakawa Y, Mayumi M (1996): Infection with hepatitis GB virus C in patients on maintenance hemodialysis. New England Journal of Medicine 334:1485-1490.
15. Mizokami M, Lau JYN, Suzuki K, Nakano T, Gojobori T (1994): Differential sensitivity of hepatitis C virus quasispecies to interferon-α therapy. Journal of Hepatology 21:884-886.
16. Muerhoff AS, Simons JN, Leary TP, Erker JC, Chalmers ML, Pilot-Matias TJ, Dawson J, Desai SM, Mushahwar IK (1996): Sequence heterogeneity within the 5′-terminal region of the hepatitis GB virus C genome and evidence for genotypes. Journal of Hepatology 25:379-384.
17. Mukaide M, Mizokami M, Orito E, Ohba K, Nakano T, Ueda R, Hikiji K, Iino S, Shapiro S, Lahat N, Park YM, Kim BS, Oyunsuren T, Rezieg M, Al-Ahdal MN, Lau JYN (1997): Three different GB virus C/hepatitis G virus genotypes - Phylogenetic analysis and a genotyping assay based on restriction fragment length polymorphism. FEBS Letters 407:51-58.
18. Nakao H, Okamoto H, Fukuda M, Tsuda F, Mitsui T, Masuko K, Iizuka H, Miyakawa Y, Mayumi M (1997): Mutation rate of GB virus C/hepatitis G virus over the entire genome and in subgenomic regions. Virology 233:43-50.
19. Ohba K, Mizokami M, Lau JYN, Orito E, Ikeo K, Gojobori T (1996): Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents. FEBS Letters 378:232-234.
20. Ohno T, Mizokami M, Wu RR, Saleh MG, Ohba K, Orito E, Mukaide M, Williams R, Lau JYN (1997): A new hepatitis C virus genotyping system that allows for identification of HCV genotypes 1a, 1b, 2a, 2b, 3a, 4, 5a, and 6a. Journal of Clinical Microbiology 35:201-207.
21. Okamoto H, Okada S, Sugiyama Y, Tanaka T, Sugai Y, Akahane Y, Machida A, Mishiro S, Yoshizawa H, Miyakawa Y, Mayumi M (1990): Detection of hepatitis C virus RNA by a two-stage polymerase chain reaction with two pairs of primers deduced from the 5′-noncoding region. Japanese Journal of Experimental Medicine 60:215-222.
22. Orito E, Mizokami M, Yasuda K, Sugihara K, Nakamura M, Mukaide M, Ohba K, Nakano T, Kato T, Kondo Y, Kumada T, Ueda R, Iino S (1997): Interferon-α therapy in patients dually infected with hepatitis C virus and GB virus C/hepatitis G virus - Virological response of HGV and pretreatment HGV viremia level. Journal of Hepatology 27:603-612.
23. Orita M, Iwahara H, Kanazawa H, Hayashi K, Sekiya T (1989): Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proceedings of the National Academy of Sciences USA 86:2766-2770.
24. Oshima M, Tsuchiya M, Yagasaki M, Orita T, Hasegawa M, Tomonoh K, Kojima T, Hirata Y, Yamamoto O, Sho Y, Maeda E, Arima T (1991): cDNA clones of Japanese hepatitis C virus genomes derived from a single patient show sequence heterogeneity. Journal of General Virology 72:2805-2809.
25. Pickering JM, Thomas HC, Karayiannis P (1997): Genetic diversity between hepatitis G virus isolates: Analysis of nucleotide variation in the NS-3 and putative 'core' peptide genes. Journal of General Virology 78:53-60.
26. Pilot-Matias TJ, Carrick RJ, Coleman PF, Leary TP, Surowy TK, Simons JN, Muerhoff AS, Buijk SL, Chalmers ML, Dawson GJ, Desai SM, Mushahwar IK (1996): Expression of the GB virus C E2 glycoprotein using the Semiliki Forest Virus vector system and its utility as a serologic marker. Virology 225:282-292.
27. Sato K, Tanaka T, Okamoto H, Miyakawa Y, Mayumi M (1996): Association of circulating hepatitis G virus with lipoproteins for a lack of binding with antibodies. Biochemical Biophysical Research Communications 229:719-725.
28. Simons JN, Leary TP, Dawson GJ, Pilot-Matias TJ, Muerhoff AS, Desai SM, Mushahwar IK (1995): Isolation of novel virus-like sequences associated with human hepatitis. Nature Medicine 1:564-569.
29. Tacke M, Kiyosawa K, Stark K, Schleuter V, Ofenloch-Haehnle B, Hess G, Engel AM (1997): Detection of antibodies to a putative hepatitis G virus envelope protein. Lancet 349:318-320.
30. Takahashi K, Hijikata M, Aoyama K, Hoshino H, Hino K, Mishiro S (1997): Characterization of GBV-C/HGV viral genome: Comparison among different isolates for a 2kb sequence that covers entire E1 and most of 5′-UTR and E2. International Hepatology Communications 6:253-263.
31. Viazov S, Riffelmann M, Khoudyakov Y, Fields H, Varenholz C, Roggendorf M (1997): Genetic heterogeneity of hepatitis G virus isolates from different parts of the world. Journal of General Virology 79:577-581.
32. Weiner AJ, Brauer MJ, Rosenblatt J, Richman KH, Tung J, Crawford K, Bonino F, Saracco G, Choo QL, Houghton M (1991): Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope glycoproteins. Virology 180:842-884.