Characterization of GBV-C/HGV viral genome: Comparison among different isolates for a ~2 kb-sequence that covers entire E1 and most of 5'UTR and E2

International Hepatology Communications

Volumn 6, Issue 5, 1997, Pages 253-263

  Takahashi, K ^a   Hijikata, M ^a   Aoyama, K ^b   Hoshino, H ^c   Hino, K ^c   Mishiro, S ^a  

^a Shinagawa ku   (Japan)

^b Hamamatsu Red Cross Hospital   (Japan)

^c NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

5' untranslated region; GBV C HGV; structural proteins; viral RNA genome

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; GENOME; HEPATITIS C; HUMAN; HUMAN TISSUE; JAPAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; VIRUS HEPATITIS;

EID: 0031080334     PISSN: 09284346     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-4346(97)00355-1     Document Type: Article

References (13)

1. [1] Simons JN, Leary TP, Dawson GJ, et al. Isolation of novel virus-like sequences associated with human hepatitis. Nat Med 1995; 1: 564-569.
2. [2] Leary TP, Muerhoff AS, Simons JN, et al. Sequence and genomic organizahon of GBV-C: a novel member of the Flaviviridae associated with human non-A-E hepatitis. J Med Virol 1996; 48: 60-67.
3. [3] Linnen J, Wages J, Zhang-Keck ZY, et al. Molecular cloning and disease association of hepatitis G virus: a transfusion-transmissible agent. Science 1996; 271: 505-508.
4. [4] Alter HJ. The cloning and clinical implications of HGV and HGBV-C. N Engl J Med 1996; 334: 1536-1537.
5. [5] Yoshiba M, Okamoto H, and Mishiro S. Detection of the GBV-C hepatitis virus genome in serum from patients with fulminant hepatitis of unknown aetiology. Lancet 1995; 346: 1131-1132.
6. [6] Zaidi Y, Chapman CS, Myint S. Aplastic anaemia after HGV infection. Lancet 1996; 348: 471-472.
7. [7] Bymes JJ, Banks AT, Piatack M Jr, et al. Hepatitis G-associated aplastic anaemia. Lancet 1996; 348: 472.
8. [8] Hijikata M, Mishiro S. Circulating immune complexes that contain HCV but not GBV-C in co-infected hosts. Int Hep Commun 1996; 5: 339-344.
9. [9] Simons JN, Desai SM, Schultz DE, et al. Translation initiation in GB viruses A and C: evidence for intemal ribosome entry and implications for genome organization. J Virol 1996; 70: 6126-6135.
10. [10] Hijikata M, Shimizu YK, Kato H, et al. Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexes. J Virol 1993; 67: 1953-1958.
11. [11] Kao JH, Chen PJ, Hsiang SC, et al. Phylogenetic analysis of GB virus C: comparison of isolates from Africa, North America, and Taiwan. J Infect Dis 1996; 174: 410-413.
12. [12] Carman WF. Vaccine-associated mutants of hepatitis B virus. In: Nishioka, K., Suzuki, H., Mishiro, S., Oda, T., eds. Viral Hepatitis and Liver Disease. Tokyo: Springer-Verlag. 1994: 243-247.
13. [13] Weiner AJ, Brauer MJ, Rosenblatt J, et al. Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins. Virology 1991; 180: 842-848.