Growth factors and acute renal failure

Seminars in Nephrology

Volumn 18, Issue 2, 1998, Pages 191-207

  Hirschberg, Raimund ^a   Ding, Hu ^a  

^a HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA;

ACUTE KIDNEY FAILURE; APOPTOSIS; CELL DIFFERENTIATION; GROWTH REGULATION; HUMAN; KIDNEY BLOOD FLOW; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION; REGENERATION; REVIEW; TISSUE REPAIR;

ANIMALS; GENE EXPRESSION; GROWTH SUBSTANCES; HUMANS; KIDNEY; KIDNEY FAILURE, ACUTE; RECEPTORS, GROWTH FACTOR;

EID: 0031892551     PISSN: 02709295     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (160)

1. Moutons BA: New insights into the cell biology of ischemie acute renal failure. J Am Soc Nephrol 1:1263-1270, 1991
2. Racusen LC: The histopathology of acute renal failure. New Horiz 3:662-668, 1995
3. Racusen LC: Pathology of acute renal failure: structure/ function correlations. Adv Ren Replace Ther 4:3-16, 1997
4. Ueda N, Kaushal G, Shah S: Recent advances in understanding mechanisms of renal tubular injury. Adv Renal Repl Therap 4:17-24, 1997 (Suppl 1)
5. Schumer M, Colombel MC, Sawczuk IS, et al: Morphologic, biochemical, and molecular evidence of apoptosis during the reperfusion phase after brief periods of renal ischemia. Am J Pathol 140:831-838, 1992
6. Goligorsky MS, Lieberthal W, Racusen L, et al: Integrin receptors in renal tubular epithelium: New insights into pathophysiology of acute renal failure [editorial]. Am J Physiol 264:Fl-8, 1993
7. Megyesi J, Di Mari J, Udvarhelyi N, et al: DNA synthesis is dissociated from the immediate-early gene response in the post-ischemic kidney. Kidney Int 48:1451-1458, 1995
8. Verstrepen WA, Nouwen EJ, Zhu MQ, et al: Time course of growth factor expression in mercuric chloride acute renal failure. Nephrol Dial Transplant 10:1361-1371, 1995
9. Verstrepen WA, Nouwen EJ, Yue XS, et al: Altered growth factor expression during toxic proximal tubular necrosis and regeneration. Kidney Int 43:1267-1279, 1993
10. Calvet JP, Chadwick LJ: Primary and secondary genetic responses after folic acid-induced acute renal injury in the mouse. J Am Soc Nephrol 5:1324-1332, 1994
11. Hise MK, Li L, Mantzouris N, et al: Differential mRNA expression of insulin-like growth factor system during renal injury and hypertrophy. Am J Physiol 269:F817-824, 1995
12. Beerli RR, Hynes NE: Epidermal growth factor-related peptides activate distinct subsets of ErbB receptors and differ in their biological activities. J Biol Chem 271:6071-6076, 1996
13. Wen D, Peles E, Cupples R, et al: Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit. Cell 69:559-572, 1992
14. Salido EC, Lakshmanan J, Fisher DA, et al: Expression of epidermal growth factor in the rat kidney. An immunocytochemical and in situ hybridization study. Histochemistry 96:65-72, 1991
15. Lakshmanan J, Salido EC, Lam R, et al: Identification of pro-epidermal growth factor and high molecular weight epidermal growth factors in adult mouse urine. Biochem Biophys Res Commun 173:902-911, 1990
16. Lakshmanan J, Salido EC, Lam R, et al: Epidermal growth factor prohormone is secreted in human urine. Am J Physiol 263:E142-150, 1992
17. Liu ZH: Epidermal growth factor and its receptor in the renal tissue of patients with acute renal failure and normal persons. Chung Hua I Hsueh Tsa Chin (Taipei) 72:593-595,1992
18. Press MF, Cordon-Cardo C, Slamon DJ: Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissues. Oncogene 5:953-962, 1990
19. Safirstein R, Zelent AZ, Price PM: Reduced renal prepro-epidermal growth factor mRNA and decreased EGF excretion in ARF. Kidney Int 36:810-815, 1989
20. Price PM, Megyesi J, Saggi S, et al: Regulation of transcription by the rat EOF gene promoter in normal and ischemie murine kidney cells. Am J Physiol 268:F664-670, 1995
21. Taira T, Yoshimura A, Ideura T, et al: Clinical significance of urinary epidermal growth factor levels in patients with acute renal failure [letter]. Nephron 60:375, 1992
22. Taira T, Yoshimura A, lizuka K, et al: Changes of urinary human epidermal growth factor excretion in 16 patients with acute renal failure. Nippon Jinzo Gakkai Shi 34:191-198, 1992
23. Taira T, Yoshimura A, lizuka K, et al: Urinary epidermal growth factor levels in patients with acute renal failure. Am J Kidney Dis 22:656-661, 1993
24. Taira T, Yoshimura A, Inui K, et al: Immunochemical study of epidermal growth factor in rats with mercuric chloride-induced acute renal failure. Nephron 67:88-93, 1994
25. Taira T, Yoshimura A, lizuka K, et al: Expression of epidermal growth factor and its receptor in rabbits with ischaemic acute renal failure. Virchows Arch 427:583-588, 1996
26. Hise M, Liu L, Papadimitriou J, et al: Transforming growth factor-alpha expression during acute renal failure. J Am Soc Nephrol 7:1658, 1996 (abstr)
27. Cowley BD, Gudapaty S: Temporal alterations in regional gene expression after nephrotoxic renal injury. J Lab Clin Med 125:187-199, 1995
28. Rogers SA, Miller SB, Hammerman MR: Altered EGF expression and thyroxine metabolism in kidneys following acute ischemie injury in rat. Am J Physiol 270:F21-30, 1996
29. Nonclercq D, Toubeau G, Lambricht P, et al: Redistribution of epidermal growth factor immunoreactivity in renal tissue after nephrotoxin-induced tubular injury. Nephron 57:210-215, 1991
30. lizuka K: Immunohistochemical localization of epidermal growth factor in proximal tubules of rats with acute renal failure. Nippon Jinzo Gakkai Shi 35:1015-1021, 1993
31. Schaudies RP, Nonclercq D, Nelson L, et al: Endogenous EGF as a potential renotrophic factor in ischemia-induced acute renal failure. Am J Physiol 265:F425-434, 1993
32. Schaudies RP, Johnson JP: Increased soluble EGF after ischemia is accompanied by a decrease in membraneassociated precursors. Am J Physiol 264:F523-531, 1993
33. Humes HD, Cieslinski DA, Johnson LB, et al: Triiodothyronine enhances renal tubule cell replication by stimulat-ing EGF receptor gene expression. Am J Physiol 262:F540-545, 1992
34. Seiken G, Grillo FG, Schaudies RP, et al: Modulation of renal EGF in dichromate-induced acute renal failure treated with thyroid hormone. Kidney Int 45:1622-1627, 1994
35. Homma T, Sakai M, Cheng HF, et al: Induction of heparin-binding epidermal growth factor-like growth factor mRNA in rat kidney after acute injury. J Clin Invest 96:1018-1025, 1995
36. Sakai M, Zhang M, Homma T, et al: Production of heparin binding epidermal growth factor-like growth factor in the early phase of regeneration after acute renal injury. Isolation and localization of bioactive molecules. J Clin Invest 99:2128-2138, 1997
37. Quigley R, Baum M: Effects of epidermal growth factor and transforming growth factor-alpha on rabbit proximal tubule solute transport. Am J Physiol 266:F459-465, 1994
38. Deguchi J, Kawabata T, Kondo A, et al: Transforming growth factor-alpha expression of renal proximal tubules in Wistar rats treated with ferric and aluminum nitrilotriacetate. Jpn J Cancer Res 84:649-655, 1993
39. Journe F, Wattiez R, Severyns C, et al: Transforming growth factor-alpha and epidermal growth factor in hamster tissues: Biochemical and immunohistochemical studies. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 112:187-200, 1995
40. Horan T, Wen J, Arakawa T, et al: Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3. J Biol Chem 270:24604-24608, 1995
41. Holmes WE, Sliwkowski MX, Akita RW, et al: Identification of heregulin, a specific activator of p185erbB2. Science 256:1205-1210, 1992
42. Sasada R, Ono Y, Taniyama Y, et al: Cloning and expression of cDNA encoding human betacellulin, a new member of the EGF family. Biochem Biophys Res Commun 190:1173-1179, 1993
43. Shing Y, Christofori G, Hanahan D, et al: Betacellulin: A mitogen from pancreatic beta cell tumors. Science 259:1604-1607, 1993
44. Modjtahedi H, Dean C: Monoclonal antibodies to the EGF receptor act as betacellulin antagonists. Biochem Biophys Res Commun 221:625-630, 1996
45. Riese DJ, Kim ED, Elenius K, et al: The epidermal growth factor receptor couples transforming growth factoralpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4. J Biol Chem 271:20047-20052, 1996
46. Riese DJn, Bermingham Y, van Raaij TM, et al: Betacellulin activates the epidermal growth factor receptor and erbB-4, and induces cellular response patterns distinct from those stimulated by epidermal growth factor or neuregulinbeta. Oncogene 12:345-353, 1996
47. Watanabe T, Shintani A, Nakata M, et al: Recombinant human betacellulin. Molecular structure, biological activities, and receptor interaction. J Biol Chem 269:9966-9973, 1994
48. Sasada R, Igarashi K: Betacellulin: A new growth factor for vascular smooth muscle cells. Nippon Rinsho 51:3308-3317, 1993
49. Humes HD, Cieslinski DA, Coimbra TM, et al: Epidermal growth factor enhances renal tubule cell regeneration and repair and accelerates the recovery of renal function in postischemic acute renal failure. J Clin Invest 84:1757-1761, 1989
50. Norman J, Tsau YK, Bacay A, et al: Epidermal growth factor accelerates functional recovery from ischaemic acute tubular necrosis in the rat: Role of the epidermal growth factor receptor. Clin Sei (Colch) 78:445-450, 1990
51. Gesualdo L, Di Paolo S, Calabro A, et al: Expression of epidermal growth factor and its receptor in normal and diseased human kidney: An immunohistochemical and in situ hybridization study. Kidney Int 49:656-665, 1996
52. Kokai Y, Dobashi K, Weiner DB, et al: Phosphorylation process induced by epidermal growth factor alters the oncogenic and cellular neu (NGL) gene products. Proc Natl Acad Sci U S A 85:5389-5393, 1988
53. Tashiro K, Hagiya M, Nishizawa T, et al: Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues. Proc Natl Acad Sci U S A 87:3200-3204, 1990
54. Miyazawa K, Shimomura T, Kitamura N: Activation of hepatocyte growth factor in the injured tissues is mediated by hepatocyte growth factor activator. J Biol Chem 271:3615-3618, 1996
55. Okajima A, Miyazawa K, Naitoh Y, et al: Induction of hepatocyte growth factor activator messenger RNA in the liver following tissue injury and acute inflammation. Hepatology 25:97-102, 1997
56. Ferracini R, Longati P, Naldini L, et al: Identification of the major autophosphorylation site of the Met/hepatocyte growth factor receptor tyrosine kinase. J Biol Chem 266:19558-19564, 1991
57. Bottaro DP, Rubin JS, Faletto DL, et al: Identification of the hepatocyte growth factor receptor as the c-met protooncogene product. Science 251:802-804, 1991
58. Selden C, Johnstone R, Darby H, et al: Human serum does contain a high molecular weight hepatocyte growth factor: Studies pre- and post-hepatic resection. Biochem Biophys Res Commun 139:361-366, 1986
59. Sugimura K, Lee CC, Kim T, et al: Production of hepatocyte growth factor is increased in chronic renal failure. Nephron 75:7-12, 1997
60. Igawa T, Matsumoto K, Kanda S, et al: Hepatocyte growth factor may function as a renotropic factor for regeneration in rats with acute renal injury. Am J Physiol 265:F6169, 1993
61. Yanagita K, Nagaike M, Ishibashi H, et al: Lung may have an endocrine function producing hepatocyte growth factor in response to injury of distal organs. Biochem Biophys Res Commun 182:802-809, 1992
62. Kono S, Nagaike M, Matsumoto K, et al: Marked induction of hepatocyte growth factor mRNA in intact kidney and spleen in response to injury of distant organs. Biochem Biophys Res Commun 186:991-998, 1992
63. Libetta C, Rampino T, Fornoni A, et al: Role of hepatic growth factor (HGF) in acute renal failure (ARF). J Am Soc Nephrol 7:1375, 1996 (abstr)
64. Wang S, Hirschberg R: Possible pathophysiologic action of HGF through apical tubular membrane c-met. J Am Soc Nephrol 8:632, 1997 (abstr)
65. Yoshinaga Y, Matsuno Y, Fujita S, et al: Immunohis-tochemical detection of hepatocyte growth factor/scatter factor in human cancerous and inflammatory lesions of various organs. Jpn J Cancer Res 84:1150-1158, 1993
66. Kobayashi T, Honke K, Miyazaki T, et al: Hepatocyte growth factor specifically binds to sulfoglycolipids. J Biol Chem 269:9817-9821, 1994
67. Kawaida K, Matsumoto K, Shimazu H, et al: Hepatocyte growth factor prevents acute renal failure and accelerates renal regeneration in mice. Proc Natl Acad Sci U S A 91:4357-4361, 1994
68. Miller SB, Martin DR, Kissane J, et al: Hepatocyte growth factor accelerates recovery from acute ischemie renal injury in rats. Am J Physiol 266:F129-134, 1994
69. Amaike H, Matsumoto K, Oka T, et al: Preventive effect of hepatocyte growth factor on acute side effects of cyclosporin A in mice. Cytokine 8:387-394, 1996
70. Takada S, Namiki M, Takahara S, et al: HGF prevents tacrolimus (FK 506)-induced nephrotoxicity in SHR rats. Transplant Proc 28:1089-1090, 1996
71. Baxter RC, Dai J: Purification and characterization of the acid-labile subunit of rat serum insulin-like growth factor binding protein complex. Endocrinology 134:848-852, 1994
72. Wilson EM, Oh Y, Rosenfeld RG: Generation and characterization of an IGFBP-7 antibody: Identification of 31kD IGFBP-7 in human biological fluids and Hs578T human breast cancer conditioned media. J Clin Endocrinol Metab82:1301-1303, 1997
73. Jones JI, Clemmons DR: Insulin-like growth factors and their binding proteins: Biological actions. Endocrinol Rev 16:3-34, 1995
74. Kelley KM, Oh Y, Gargosky SE, et al: Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics. Int J Biochem Cell Biol 28:619-637, 1996
75. Andersson GL, Skottner A, Jennische E: Immunocytochemical and biochemical localization of insulin-like growth factor I in the kidney of rats before and after uninephrectomy. Acta Endocrinol (Copenh) 119:555-560, 1988
76. Matejka GL, Eriksson PS, Carlsson B, et al: Distribution of IGF-I mRNA and IGF-I binding sites in the rat kidney. Histochemistry 97:173-180, 1992
77. Andersson GL, Ericson LE, Jennische E: Ultrastructural localization of IGF-I in the rat kidney; an immunocytochemical study. Histochemistry 94:263-267, 1990
78. Chin E, Bondy C: Insulin-like growth factor system gene expression in the human kidney. J Clin Endocrinol Metab 75:962-968, 1992
79. Chin E, Zhou J, Bondy CA: Renal growth hormone receptor gene expression: Relationship to renal insulin-like growth factor system. Endocrinology 131:3061-3066, 1992
80. Chin E, Zhou J, Bondy C: Anatomical relationships in the patterns of insulin-like growth factor (IGF)-I, IGF binding protein-1, and IGF-I receptor gene expression in the rat kidney. Endocrinology 130:3237-3245, 1992
81. Chin E, Zhou J, Dai J, et al: Cellular localization and regulation of gene expression for components of the insulinlike growth factor ternary binding protein complex. Endocrinology 134:2498-2504, 1994
82. Landau D, Chin E, Bondy C, et al: Expression of insulin-like growth factor binding proteins in the rat kidney: Effects of long-term diabetes. Endocrinology 136:1835-1842, 1995
83. Bortz JD, Rotwein P, De Vol D, et al: Focal expression of insulin-like growth factor I in rat kidney collecting duct. J Cell Biol 107:811-819, 1988
84. Hammerman MR, Rogers S: Distribution of IGF receptors in the plasma membrane of proximal tubular cells. Am J Physiol 253:F841-847, 1987
85. Jones JI, Gockerman A, Busby WH, Jr., et al: Extracellular matrix contains insulin-like growth factor binding protein-5: Potentiation of the effects of IGF-I. J Cell Biol 121:679-687, 1993
86. Jones JI, Gockerman A, Busby WH, Jr., et al: Insulinlike growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its ArgGly-Asp sequence. Proc Natl Acad Sci U S A 90:10553-10557, 1993
87. Ruoslahti E, Pierschbacher MD: New perspectives in cell adhesion: RGD and integrins. Science 238:491-497, 1987
88. Matejka GL, Jennische E: IGF-I binding and IGF-I mRNA expression in the post-ischemic regenerating rat kidney. Kidney Int 42:1113-1123, 1992
89. Ding H, Gao X, Hirschberg R, et al: Time dependent changes in the expression of insulin-like growth factor-I and IGF-I receptor in tisues of rats with acute renal failure. J Am Soc Nephrol 6:461, 1995 (abstr)
90. Tsao T, Wang J, Fervenza FC, et al: Renal growth hormone-insulin-like growth factor-I system in acute renal failure. Kidney Int 47:1658-1668, 1995
91. Bohe J, Ding H, Hirschberg R, et al: Insulin-like growth factor binding proteins and IGFBP mRNAs in rats with acute renal failure given IGF-I. J Am Soc Nephrol 7:1653, 1996 (abstr)
92. Fervenza FC, Tsao T, Rabkin R: Response of the intrarenal insulin-like growth factor-I axis to acute ischemie injury and treatment with growth hormone and epidermal growth factor. Kidney Int 49:344-354, 1996
93. Friedlaender M, Popovtzer MM, Weiss O, et al: Insulin-like growth factor-1 (IGF-1) enhances recovery from HgC12-induced acute renal failure: the effects on renal IGF1, IGF-1 receptor, and IGF-binding protein-1 mRNA. J Am Soc Nephrol 5:1782-1791, 1995
94. Hirschberg R, Kopple JD: Evidence that insulin-like growth factor I increases renal plasma flow and glomerular filtration rate in fasted rats. J Clin Invest 83:326-330, 1989
95. Hirschberg R, Kopple JD, Blantz RC, et al: Effects of recombinant human insulin-like growth factor I on glomerular dynamics in the rat. J Clin Invest 87:1200-1206, 1991
96. Hirschberg R, Brunori G, Kopple JD, et al: Effects of insulin-like growth factor I on renal function in normal men. Kidney Int 43:387-397, 1993
97. Ding H, Kopple JD, Cohen A, et al: Recombinant human insulin-like growth factor-I accelerates recovery and reduces catabolism in rats with ischemie acute renal failure. J Clin Invest 91:2281-2287, 1993
98. Clark R, Mortensen D, Rabkin R: Recovery from acute ischaemic renal failure is accelerated by des-(1-3)-insulinlike growth factor-1. Clin Sci (Colch) 86:709-714, 1994
99. Lin JJ, Cybulsky AV, Goodyer PR, et al: Insulin-like growth factor-1 enhances epidermal growth factor receptor activation and renal tubular cell regeneration in postischemic acute renal failure [see comments]. J Lab Clin Med 125:724-733, 1995
100. Noguchi S, Kashihara Y, Ikegami Y, et al: Insulinlike growth factor-I ameliorates transient ischemia-induced acute renal failure in rats. J Pharmacol Exp Ther 267:919-926, 1993
101. Miller SB, Martin DR, Kissane J, et al: Insulin-like growth factor I accelerates recovery from ischemie acute tubular necrosis in the rat. Proc Natl Acad Sci U S A 89:11876-11880, 1992
102. Martin AA, Gillespie CM, Moore L, et al: Effects of insulin-like growth factor-I peptides in rats with acute renal failure. J Endocrinol 140:23-32, 1994
103. Miller SB, Martin DR, Kissane J, et al: Rat models for clinical use of insulin-like growth factor I in acute renal failure. Am J Physiol 266:F949-956, 1994
104. Petrinec D, Reilly JM, Sicard GA, et al: Insulin-like growth factor-I attenuates delayed graft function in a canine renal autotransplantation model. Surgery 120:221-225; discussion 225-226, 1996
105. Hirschberg R, Ding H: Mechanisms of IGF-I-induced accelerated tubular recovery in ischemie acute renal failure. Miner Electrolyte Metab (In Press) 1998
106. Hirschberg R, Ding H: Mechanism of IGF-I-induced recovery of proximal tubular cells in primary culture after acute renal injury. J Am Soc Nephrol 7:1826, 1996 (abstr)
107. Kramer BK, Bucher M, Sandner P, et al: Effects of hypoxia on growth factor expression in the rat kidney in vivo. Kidney Int 51:444-447, 1997
108. Ichimura T, Finch PW, Zhang G, et al: Induction of FGF-7 after kidney damage: A possible paracrine mechanism for tubule repair. Am J Physiol 271:F967-976, 1996
109. Ichimura T, Maier JA, Maciag T, et al: FGF-1 in normal and regenerating kidney: Expression in mononuclear, interstitial, and regenerating epithelial cells. Am J Physiol 269:F653-662, 1995
110. Hughes SE, Hall PA: Immunolocalization of fibroblast growth factor receptor 1 and its ligands in human tissues. Lab Invest 69:173-182, 1993
111. Cauchi J, Alcorn D, Cancilla B, et al: Light-microscopic immunolocalization of fibroblast growth factor-1 and -2 in adult rat kidney. Cell Tissue Res 285:179-187, 1996
112. Zhang G, Ichimura T, Maier JA, et al: A role for fibroblast growth factor type-1 in nephrogenic repair. Autocrine expression in rat kidney proximal tubule epithelial cells in vitro and in the regenerating epithelium following nephrotoxic damage by S-(1,1,2,2-tetrafiuoroethyl)-L-cysteine in vivo. J Biol Chem 268:11542-11547, 1993
113. Roberts A: The molecular and cell biology of TGFbeta. Miner Electrolyte Metab (In Press) 1998
114. Wrana J: TGF-beta receptors and signaling mechanisms. Miner Electrolyte Metab (In Press) 1998
115. Wrana J, Attisano L, Wieser R, et al: Mechanism of activation of the TGF-beta receptor. Nature 370:341-341, 1994
116. Oberhammer FA, Pavelka M, Sharma S, et al: Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1. Proc Natl Acad Sci U S A 89:5408-5412, 1992
117. Hocevar B, Howe P: Mechanisms of transforming growth factor-beta induced cell cycle arrest. Miner Electrolyte Metab (In Press) 1998
118. Ando T, Okuda S, Tamaki K, et al: Localization of transforming growth factor-beta and latent transforming growth factor beta binding protein in rat kidney. Kidney Int 47:733-739, 1995
119. Ando T, Okuda S, Yanagida T, et al: Localization of TGF-beta and its receptors in the kidney. Miner Electrolyte Metab (In Press) 1998
120. Basile DP, Rovak JM, Martin DR, et al: Increased transforming growth factor-beta 1 expression in regenerating rat renal tubules following ischemie injury. Am J Physiol 270:F500-509, 1996
121. Shimizu A, Yamanaka N: Apoptosis and cell desquamation in repair process of ischemie tubular necrosis. Virchows Arch B Cell Pathol Incl Mol Pathol 64:171-180, 1993
122. Rogers SA, Miller SB, Hammerman MR: Insulinlike growth factor I gene expression in isolated rat renal collecting duct is stimulated by epidermal growth factor. J Clin Invest 87:347-351, 1991
123. Barnard JA, Graves-Deal R, Pittelkow MR, et al: Auto- and cross-induction within the mammalian epidermal growth factor-related peptide family. J Biol Chem 269:22817-22822, 1994
124. Rubini M, Werner H, Gandini E, et al: Platelet-derived growth factor increases the activity of the promoter of the insulin-like growth factor-1 (IGF-1) receptor gene. Exp Cell Res 211:374-379, 1994
125. Hernandez-Sanchez C, Werner H, Roberts C, et al: Differential regulation of insulin-like growth factor-I (IGFI) receptor gene expression by IGF-I and basic fibroblastic growth factor. J Biol Chem 272:4663-4670, 1997
126. Marshall SM, Flyvbjerg A, Jorgensen KD, et al: Effects of growth hormone and thyroxine on kidney insulinlike growth factor-I and renal growth in hypophysectomized rats. J Endocrinol 136:399-406, 1993
127. Morgan DO: Principles of CDK regulation. Nature 374:131-134, 1995
128. Ravitz MJ, Wenner CE: Cyclin-dependent kinase regulation during G1 phase and cell cycle regulation by TGFbeta. Adv Cancer Res 71:165-207, 1997
129. Montesano R, Matsumoto K, Nakamura T, et al: Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell 67:901-908, 1991
130. Gailit J, Colflesh D, Rabiner I, et al: Redistribution and dysfunction of integrins in cultured renal epithelial cells exposed to oxidative stress. Am J Physiol 264:F149-157, 1993
131. Cantley LG: Growth factors and the kidney: Regulation of epithelial cell movement and morphogenesis. Am J Physiol 271:F1103-1113, 1996
132. Beeri R, Symon Z, Brezis M, et al: Rapid DNA fragmentation from hypoxia along the thick ascending limb of rat kidneys. Kidney Int 47:1806-1810, 1995
133. Bonventre JV: Mechanisms of ischemie acute renal failure [clinical conference]. Kidney Int 43:1160-1178, 1993
134. Lieberthal W, Levine JS: Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury. Am J Physiol 271:F477-488, 1996
135. Ortiz A, Ziyadeh FN, Neilson EG: Expression of apoptosis-regulatory genes in renal proximal tubular epithelial cells exposed to high ambient glucose and in diabetic kidneys. J Invest Med 45:50-56, 1997
136. Savill J: Apoptosis and renal injury. Curr Opin Nephrol Hypertens 4:263-269, 1995
137. Ueda N, Walker PD, Hsu SM, et al: Activation of a 15-kDa endonuclease in hypoxia/reoxygenation injury without morphologic features of apoptosis. Proc Natl Acad Sci USA 92:7202-7206, 1995
138. Zager RA: Pathogenetic mechanisms in nephrotoxic acute renal failure. Semin Nephrol 17:3-14, 1997
139. Matsuno T, Nakagawa K, Sasaki H, et al: Apoptosis in acute tubular necrosis and acute renal allograft rejection. Transplant Proc 26:2170-2173, 1994
140. Woo D: Apoptosis and loss of renal tissue in polycystic kidney diseases [see comments]. N Engl J Med 333:1825, 1995
141. Fraser A, Evan G: A license to kill. Cell 85:781-784, 1996
142. Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science 267:1456-1462, 1995
143. Frisch SM, Francis H: Disruption of epithelial cellmatrix interactions induces apoptosis. J Cell Biol 124:619-626, 1994
144. Basile DP, Liapis H, Hammerman MR: Expression of bcl-2 and bax in regenerating rat renal tubules following ischemie injury. Am J Physiol 272:F640-647, 1997
145. Ding H, Gao XL, Hirschberg R, et al: Impaired actions of insulin-like growth factor I on protein synthesis and degradation in skeletal muscle of rats with chronic renal failure. Evidence for a postreceptor defect. J Clin Invest 97:1064-1075, 1996
146. Parrizas M, LeRoith D: Insulin-like growth factor-1 inhibition of apoptosis is associated with increased expression of the bcl-xL gene product. Endocrinology 138:1355-1358, 1997
147. Parrizas M, Saltiel AR, LeRoith D: Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways. J Biol Chem 272:154-161, 1997
148. Franke TF, Kaplan DR, Cantley LC: PI3K: Downstream AKTion blocks apoptosis. Cell 88:435-437, 1997
149. Bardelli A, Longati P, Albero D, et al: HGF receptor associates with the anti-apoptotic protein BAG-1 and prevents cell death. Embo J 15:6205-6212, 1996
150. Grimm S, Leder P: An apoptosis-inducing isoform of neu differentiation factor (NDF) identified using a novel screen for dominant, apoptosis-inducing genes. J Exp Med 185:1137-1142, 1997
151. Haylor J, Singh I, el Nahas AM: Nitric oxide synthesis inhibitor prevents vasodilation by insulin-like growth factor I. Kidney Int 39:333-335, 1991
152. Tsukahara H, Gordienko DV, Tonshoff B, et al: Direct demonstration of insulin-like growth factor-I-induced nitric oxide production by endothelial cells. Kidney Int 45:598-604, 1994
153. Feinstein E, Blumenkrantz M, Healy M, et al: Clinical and metabolic responses to parenteral nutrition in acute renal failure. A controlled double-blind study. Medicine 60:124-137, 1981
154. Flügel-Link R, Salusky I, Jones M, et al: Protein and amino acid metabolism in posterior hemicorpus of acutely uremie rats. Am J Physiol 244:E615-E623, 1983
155. Clark A, Mitch W: Muscle protein turnover and glucose uptake in acutely uremie rats. J Clin Invest 72:836-845, 1983
156. Franklin SC, Moulton M, Sicard GA, et al: Insulinlike growth factor I preserves renal function postoperatively. Am J Physiol 272:F257-259, 1997
157. Kopple J, Hirschberg R, Guler H, et al: Lack of effect of recombinant human insulin-like growth factor I in patients with acute renal failure. J Am Soc Nephrol 7:1375, 1996 (abstr)
158. Alison MR, Nasim MM, Anilkumar TV, et al: Transforming growth factor-alpha immunoreactivity in a variety of epithelial tissues. Cell Prolif 26:449-460, 1993
159. Diaz-Ruiz C, Asbert M, Perez-Tomas R: Immunochemical study of a transforming growth factor-alpha-related protein in the chicken kidney. Kidney Int 49:1053-1063, 1996
160. Vaughan TJ, James PS, Pascall JC, et al: Molecular cloning and tissue distribution of pig transforming growth factor alpha. Biochem J 296:837-842, 1993