Preventive effect of hepatocyte growth factor on acute side effects of cyclosporin A in mice

Cytokine

Volumn 8, Issue 5, 1996, Pages 387-394

  Amaike, Hisashi ^a   Matsumoto, Kunio ^a   Oka, Takahiro ^b   Nakamura, Toshikazu ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Cyclosporin A; Hepatocyte growth factor; Organotrophic factor

Indexed keywords

CYCLOSPORIN A; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; MESSENGER RNA; RECOMBINANT PROTEIN; SCATTER FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEGENERATION; CONTROLLED STUDY; DNA SYNTHESIS; GENE INDUCTION; HISTOLOGY; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY TUBULE CELL; LIVER CELL; LIVER HISTOLOGY; LIVER TOXICITY; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL;

EID: 0029955256     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1996.0053     Document Type: Article

References (52)

1. European Multicentre Trial Group (1987) Cyclosporine in cadaveric renal transplantation: 5-year follow-up of a multicentre trial. Lancet 2:506-507.
2. Kahan BD (1989) Cyclosporine. N Engl J Med 321:1725-1738.
3. Ryffel B, Donatsch P, Madörin M, Matter BE, Rüttimann G, Schön H, Stoll R, Wilson J (1983) Toxicological evaluation of cyclosporin A. Arch Toxicol 53:107-141.
4. Myer BD, Ross J, Newton L, Luctscher J, Perlroth M (1984) Cyclosporine-associated chronic nephropathy. N Engl J Med 311:699-708.
5. Kahan BD (1985) Individualization of cyclosporine therapy using pharmacokinetic and pharmacodynamic parameters. Transplantation 40:457-476.
6. McNally PG, Feehally J (1992) Pathophysiology of cyclosporin A nephrotoxicity: experimental and clinical observations. Nephrol Dial Transplant 7:791-804.
7. Nakamura T, Nawa K, Ichihara A (1984) Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats. Biochem Biophys Res Commun 122:1450-1459.
8. Nakamura T, Teramoto H, Ichihara A (1986) Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures. Proc Natl Acad Sci USA 83:6489-6493.
9. Ghoda E, Tsubouchi H, Nakayama H, Hirono S, Sakiyama O, Takahashi K, Miyazawa H, Hashimoto S, Daikuhara Y (1988) Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure. J Clin Invest 81:414-419.
10. Zarnegar R, Michalopoulos G (1989) Purification and biological characterization of human hepatopoietin A, a polypeptide growth factor for hepatocyte. Cancer Res 49:3314-3320.
11. Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M, Sugiura A, Tashiro K, Shimizu S (1989) Molecular cloning and expression of human hepatocyte growth factor. Nature 342:440-443.
12. Tashiro K, Hagiya M, Nishizawa T, Seki T, Shimonishi M, Shimizu S, Nakamura T (1990) Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues. Proc Natl Acad Sci USA 87:3200-3204.
13. Matsumoto K, Nakamura T (1993) Roles of HGF as a pleiotropic factor in organ regeneration. In Goldberg ID, Rosen EM (eds.) Hepatocyte Growth Factor-Scatter Factor (HGF-SF) and c-MET Receptor, Birkhäuser Verlag, Basel, pp 225-249.
14. Weidner KM, Arakaki N, Hartmann G, Vandekerckhove J, Weingart S, Rieder H, Fontasch C, Tsubouchi H, Hishida T, Daikuhara Y, Birchmeier W (1991) Evidence for the identity of human scatter factor and human hepatocyte growth factor. Proc Natl Acad Sci USA 88:7001-7005.
15. Furlong RA, Takehara T, Taylor WG, Nakamura T, Rubin JS (1991) Comparison of biological and immunochemical properties indicates that scatter factor and hepatocyte growth factor are indistinguishable. J Cell Sci 100:173-177.
16. Montesano R, Matsumoto K, Nakamura T, Orci L (1991) Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell 67:901-908.
17. Johnson M, Koukoulis G, Matsumoto K, Nakamura T, Iyer A (1993) Hepatocyte growth factor induces proliferation and morphogenesis in nonparenchymal epithelial liver cells. Hepatology 17:1052-1061.
18. Bottaro DP, Rubin JS, Faletto DL, Chan AML, Kmiecik TE, Vande Woude GF, Aaronson SA (1991) Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 251:802-804.
19. Naldini L, Vigna E, Narsimham RP, Gaudino G, Zarnegar R, Michalopoulos GK, Comoglio PM (1991) Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET. Oncogene 6:501-504.
20. Higuchi O, Mizuno K, Vande Woude GF, Nakamura T (1992) Expression of c-met proto-oncogene in COS cells induced the signal transducing high-affinity receptor for hepatocyte growth factor. FEBS Lett 301:282-286.
21. Jiang WG, Hallett MB, Puntis MCA (1993) Hepatocyte growth factor/Scatter factor, liver regeneration and cancer metastasis. Br J Surg: 1368-1373.
22. Matsumoto K, Nakamura T (1994) Pleiotropic roles of HGF in mitogenesis, morphogenesis, and organ regeneration. Gann Monograph 42:91-112.
23. Kawaida K, Matsumoto K, Shimazu H, Nakamura T (1994) Hepatocyte growth factor prevents acute renal failure and accelerates renal regeneration in mice. Proc Natl Acad Sci USA 91:4357-4361.
24. Igawa T, Matsumoto K, Kanda S, Saito Y, Nakamura T. Hepatocyte growth factor may function as a renotropic factor for regeneration in rats with acute renal injury. Am J Physiol 1993, 265:F61-F69.
25. Yanagita K, Matsumoto K, Sekiguchi K, Ishibashi H, Niho Y, Nakamura T (1993) Hepatocyte growth factor may act as a pulmotrophic factor on lung regeneration after acute lung injury. J Biol Chem 268:21212-21217.
26. Kinoshita T, Tashiro K, Nakamura T (1989) Marked increase of HGF mRNA in non-parenchymal liver cells of rats treated with hepatotoxins. Biol Biophys Res Commun 165:1229-1234.
27. Ishiki Y, Ohnishi H, Muto Y, Matsumoto K, Nakamura T (1992) Direct evidence that hepatocyte growth factor is a hepatotrophic factor for liver regeneration and has a potent antihepatitis effect in vivo. Hepatology 16:1227-1235.
28. Hess AD, Tutschka PJ, Santos GW (1982) Effects of cyclosporin A on human lymphocyte responses in vitro. III CsA inhibits the production of T lymphocyte growth factors in secondary mixed lymphocyte responses but does not inhibit the response of primed lymphocytes to TCGF. J Immunol 128:355-359.
29. Handschumacher RE, Harding MW, Rice J. Drugge RJ, Speicher DW (1984) Cyclophilin: A specific cytosolic binding protein for cyclosporin A. Science 226:544-547.
30. Clipstone NA, Crabtree GR (1992) Identification of calcineurin as a key signaling enzyme in T-lymphocyte activation. Nature 357:695-697.
31. Flanagan WM, Corthesy B, Bram RJ, Crabtree GR (1991) Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. Nature 352:803-807.
32. Suzuki S, Oka T, Ohkuma S, Kuriyama K (1987) Biochemical mechanisms underlying cyclosporine-induced nephrotoxicity. Transplantation 44:363-368.
33. +-ATPase activity by cyclosporin A. Kidney Int 43:246-251.
34. Andersson A, Borg H, Hallberg A, Hellertröm C, Sandler S, Schell A (1984) Long-term effects of cyclosporin A on cultured mouse pancreatic islets. Diabetologia 27:66-69.
35. 2 in rats caused by cyclosporine. Transplantation 40:214-216.
36. Coffman TM, Carr DR, Yarger WE, Klotman PE (1987) Evidence that renal prostaglandin and thromboxane production is stimulated in chronic cyclosporine nephrotoxicity. Transplantation 43:282-285.
37. Kon V, Sugiura M, Inagami T, Harvie BR, Ichikawa I, Hoover RL (1990) Role of endothelin in cyclosporine-induced glomerular dysfunction. Kidney Int 37:1487-1491.
38. Fogo A, Hellings SE, Inagami T, Kon V (1992) Endothelin receptor antagonism is protective in in vivo acute cyclosporine toxicity. Kidney Int 42:770-774.
39. Bloom ITM, Bentley FR, Garrison RN (1993) Acute cyclosporin-induced renal vasoconstriction is mediated by endothelin-1. Surgery 114:480-488.
40. Mason RJ, Leslie CC, McCormick-Shannon K, Deterding RR, Nakamura T, Rubin JS, Shannon JM (1994) Hepatocyte growth factor is a growth factor for rat alveolar type II cells. Am J Respir Cell Mol Biol 11:561-567.
41. Bussolino F, DiRenzo MF, Ziehe M, Bocchietto E, Olivero M, Naldini L, Gaudino G, Tamagnone L, Coffer A, Comoglio PM (1992) Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol 119:629-641.
42. Nusrat A, Parkos CA, Bacarra AE, Godowski PJ, Delp-Archer C, Rosen EM, Madara JL (1994) Hepatocyte growth factor/ scatter factor effects on epithelia. J Clin Invest 93:2056-2065.
43. Takehara T, Matsumoto K, Nakamura T (1992) Cell-density dependent regulation of albumin synthesis and DNA synthesis in rat hepatocytes by hepatocyte growth factor. J Biochem 112:330-334.
44. Ishibashi K, Sasaki S, Sakamoto H, Nakamura Y, Hata T, Nakamura T, Marumo F (1992) Hepatocyte growth factor is a paracrine factor for renal epithelial cells: stimulation of DNA synthesis and Na, K-ATPase activity. Biochem Biophys Res Commun 182:960-965.
45. Seki T, Ihara I, Sugiura A, Shimonishi M, Nishizawa T, Asami O, Hagiya M, Nakamura T, Shimizu S (1990) Isolation and expression of cDNA for different forms of hepatocyte growth factor from human leukocyte. Biochem Biophys Res Commun 172:321-327.
46. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
47. Weiss A, Wiskocil RL, Stobo JD (1984) The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL-2 production reflects events occurring at a pretranslational level. J Immunol 133:123-128.
48. Manger B, Weiss A, Weyand C, Goronzy J, Stobo JD (1985) T cell activation: differences in the signals required for IL 2 production by nonactivated and activated T cells. J Immunol 135:3669-3673.
49. Rong S, Bodescot M, Blair D, Dunn J, Nakamura T, Mizuno K, Park M, Chan A, Aaronson S, Vande Woude GF (1992) Tumorgenicity of the met protooncogene and the gene for hepatocyte growth factor. Mol Cell Biol 12:5152-5158.
50. Takada S, Namiki M, Takahara S, Matsumiya K, Kondoh N, Kitamura M, Uchida K, Matsumoto K, Nakamura T, Okuyama A. (1996) Early detection and prediction of prognosis in acute renal rejection by serum HGF after renal transplantation. Transplant Intern 9: (in press).
51. Takada S, Namiki MI, Takahara S, Matsumiya K, Kondoh N, Matsumoto K, Nakamura T, Okuyama A. (1996) Serum HGF levels in acute renal rejection after living related renal transplantation. Transplant Intern 9:151-154.
52. Takada S, Namiki M, Takahara S, Matsumiya K, Kondoh N, Kitamura M, Uchida K, Koga M, Hongsi J, Kokado Y, Ichimaru N, Kameoka H, Suzuki S, Sada M, Tsuji T, Miki T, Matsumoto K, Nakamura T, Okuyama A (1996) HGF prevents the tacrolimus (FK506) induced nephrotoxicity in SHR rats. Transplant Proc. (in press).