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Volumn 34, Issue SUPPL. B, 1998, Pages 1-23

Carvedilol update IV: Prevention of oxidative stress, cardiac remodeling and progression of congestive heart failure

Author keywords

[No Author keywords available]

Indexed keywords

CARVEDILOL; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; PLACEBO;

EID: 0031891643     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (1)

References (93)
  • 1
    • 0015237841 scopus 로고
    • The natural history of congestive heart failure: The Framingham study
    • McKee, P.A., Castelli, W.P., McNamara, P.M., Kannel, W.B. The natural history of congestive heart failure: The Framingham study. New Engl J Med 1971, 285: 1441-6.
    • (1971) New Engl J Med , vol.285 , pp. 1441-1446
    • McKee, P.A.1    Castelli, W.P.2    McNamara, P.M.3    Kannel, W.B.4
  • 2
    • 0025677273 scopus 로고
    • Epidemiological aspects of heart failure
    • Sutton, G.C.S. Epidemiological aspects of heart failure. Am Heart J 1990, 120: 1538-40.
    • (1990) Am Heart J , vol.120 , pp. 1538-1540
    • Sutton, G.C.S.1
  • 3
    • 0026695201 scopus 로고
    • Prevalence and mortality rate of congestive heart failure in the United States
    • Schocken, D.D., Arrieta, M.I., Laverton, P.E., Ross, E.A. Prevalence and mortality rate of congestive heart failure in the United States. J Am Coll Cardiol 1992, 20: 301-6.
    • (1992) J Am Coll Cardiol , vol.20 , pp. 301-306
    • Schocken, D.D.1    Arrieta, M.I.2    Laverton, P.E.3    Ross, E.A.4
  • 5
    • 0027438295 scopus 로고
    • Trends in hospitalization for heart failure in Scotland 1980-1990
    • McMurray, J., McDonagh, T., Morrison, C.E., Dargie, H.J. Trends in hospitalization for heart failure in Scotland 1980-1990. Eur Heart J 1993, 14: 1158-62.
    • (1993) Eur Heart J , vol.14 , pp. 1158-1162
    • McMurray, J.1    McDonagh, T.2    Morrison, C.E.3    Dargie, H.J.4
  • 6
    • 0027423351 scopus 로고
    • The epidemiology of heart failure: The Framingham Study
    • Ho, K.K., Pinsky, J.L., Kannel, W.B., Levy, D. The epidemiology of heart failure: The Framingham Study. J Am Coll Cardiol 1993, 22(4, Suppl. A): 6-13A.
    • (1993) J Am Coll Cardiol , vol.22 , Issue.4 SUPPL. A
    • Ho, K.K.1    Pinsky, J.L.2    Kannel, W.B.3    Levy, D.4
  • 7
    • 0023266532 scopus 로고
    • Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
    • The CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). New Engl J Med 1987, 316: 1429-35.
    • (1987) New Engl J Med , vol.316 , pp. 1429-1435
  • 8
    • 0026786643 scopus 로고
    • Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the Survival and Ventricular Enlargement Trial
    • Pfeffer, M.A., Braunwald, E., Moye, L.A. et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the Survival and Ventricular Enlargement Trial. New Engl J Med 1992, 327: 669-77.
    • (1992) New Engl J Med , vol.327 , pp. 669-677
    • Pfeffer, M.A.1    Braunwald, E.2    Moye, L.A.3
  • 9
    • 0025913812 scopus 로고
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
    • The SOLVD Investigators. Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. New Engl J Med 1991, 325: 293-302.
    • (1991) New Engl J Med , vol.325 , pp. 293-302
  • 10
    • 0026785561 scopus 로고
    • Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions
    • The SOLVD Investigators. Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. New Engl J Med 1992, 327: 685-91.
    • (1992) New Engl J Med , vol.327 , pp. 685-691
  • 11
    • 0022591615 scopus 로고
    • Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure
    • Leimbach, W.N., Jr., Wallin, B.G., Victor, R.G., Aylward, P.E., Sundlof, G., Mark, A.L. Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure. Circulation 1986, 73: 913-9.
    • (1986) Circulation , vol.73 , pp. 913-919
    • Leimbach Jr., W.N.1    Wallin, B.G.2    Victor, R.G.3    Aylward, P.E.4    Sundlof, G.5    Mark, A.L.6
  • 12
    • 0021194420 scopus 로고
    • Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure
    • Cohn, J.N., Levine, B., Olivari, T.M. et al. Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure. New Engl J Med 1984, 311: 819-23.
    • (1984) New Engl J Med , vol.311 , pp. 819-823
    • Cohn, J.N.1    Levine, B.2    Olivari, T.M.3
  • 13
    • 0025153828 scopus 로고
    • Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure
    • Francis, G.S., Benedict, C., Johnstone, D.E. et al. Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. Circulation 1990, 82: 1724-70.
    • (1990) Circulation , vol.82 , pp. 1724-1770
    • Francis, G.S.1    Benedict, C.2    Johnstone, D.E.3
  • 14
    • 0345513198 scopus 로고
    • Changes in plasma levels of endothelin reflect the long term clinical and hemodynamic effects of beta-blockade in patients with chronic heart failure
    • Krum, H., Gu, A., Wilshire-Clement, M. et al. Changes in plasma levels of endothelin reflect the long term clinical and hemodynamic effects of beta-blockade in patients with chronic heart failure. J Am Coll Cardiol 1994, 172A.
    • (1994) J Am Coll Cardiol
    • Krum, H.1    Gu, A.2    Wilshire-Clement, M.3
  • 16
    • 0030902115 scopus 로고
    • Randomized trial of losartan versus captopril in patients over 65 with heart failre (Evaluation of Losartain in the Elderly Study, ELITE)
    • Pitt, B., Segal, R., Martinez, F.A. et al. Randomized trial of losartan versus captopril in patients over 65 with heart failre (Evaluation of Losartain in the Elderly Study, ELITE). Lancet 1977, 349: 747-52.
    • (1977) Lancet , vol.349 , pp. 747-752
    • Pitt, B.1    Segal, R.2    Martinez, F.A.3
  • 17
    • 0016701034 scopus 로고
    • Effect of chronic β-adrenergic receptor blockade in congestive cardiomyopathy
    • Waagstein, R., Hjalmarson, A., Varnauskas, E., Wallentin, I. Effect of chronic β-adrenergic receptor blockade in congestive cardiomyopathy. Br Heart J 1975, 37: 1022-36.
    • (1975) Br Heart J , vol.37 , pp. 1022-1036
    • Waagstein, R.1    Hjalmarson, A.2    Varnauskas, E.3    Wallentin, I.4
  • 18
    • 0027135308 scopus 로고
    • Beneficial effects of metaprolol in idiopathic dilated cardiomyopathy
    • Waagstein, F., Bristow, R.M., Swedeberg, K. et al. Beneficial effects of metaprolol in idiopathic dilated cardiomyopathy. Lancet 1993, 342: 1441-6.
    • (1993) Lancet , vol.342 , pp. 1441-1446
    • Waagstein, F.1    Bristow, R.M.2    Swedeberg, K.3
  • 19
    • 0028092116 scopus 로고
    • A randomized trial of β-blockade in heart failure. The Cardiac Insufficiency Bisoprolol Study (CIBIS)
    • CIBIS. A randomized trial of β-blockade in heart failure. The Cardiac Insufficiency Bisoprolol Study (CIBIS). Circulation 1994, 90: 1765-73.
    • (1994) Circulation , vol.90 , pp. 1765-1773
  • 20
    • 0024841997 scopus 로고
    • In vitro pharmacologic profile of the novel β-adrenoceptor antagonist and vasodilator, carvedilol
    • Nichols, A.J., Sulpizio, A.C., Ashton, D.J., Hieble, J.P., Ruffolo, R.R. Jr. In vitro pharmacologic profile of the novel β-adrenoceptor antagonist and vasodilator, carvedilol. Pharmacology 1989, 39: 327-36.
    • (1989) Pharmacology , vol.39 , pp. 327-336
    • Nichols, A.J.1    Sulpizio, A.C.2    Ashton, D.J.3    Hieble, J.P.4    Ruffolo Jr., R.R.5
  • 22
    • 0025755383 scopus 로고
    • Studies on the mechanism of arterial vasodilation produced by the novel antihypertensive agent
    • Nichols, A.J., Gellai, M., Ruffolo, R.R. Jr. Studies on the mechanism of arterial vasodilation produced by the novel antihypertensive agent. Fundam Clin Pharmacol 1991, 5: 25-38.
    • (1991) Fundam Clin Pharmacol , vol.5 , pp. 25-38
    • Nichols, A.J.1    Gellai, M.2    Ruffolo Jr., R.R.3
  • 24
    • 0026526235 scopus 로고
    • Single and repeated doses of the vasodilator/β-adrenergic antagonist, carvedilol, block cirazoline- And isoproterenol-mediated hemodynamic responses in the conscious rat
    • Smith, E.F., Sliviak, M.J., Gagnon, R. Single and repeated doses of the vasodilator/β-adrenergic antagonist, carvedilol, block cirazoline- and isoproterenol-mediated hemodynamic responses in the conscious rat. Cardiovasc Drugs Ther 1992, 6: 499-504.
    • (1992) Cardiovasc Drugs Ther , vol.6 , pp. 499-504
    • Smith, E.F.1    Sliviak, M.J.2    Gagnon, R.3
  • 25
    • 0025021383 scopus 로고
    • Local cutaneous hemodynamic effects of carvedilol and labetalol in the anesthetized rat
    • Willette, R.N., Sauerrnelch, C.F., Ruffolo, R.R. Jr. Local cutaneous hemodynamic effects of carvedilol and labetalol in the anesthetized rat. Eur J Pharmacol 1990, 176: 237-40.
    • (1990) Eur J Pharmacol , vol.176 , pp. 237-240
    • Willette, R.N.1    Sauerrnelch, C.F.2    Ruffolo Jr., R.R.3
  • 26
    • 0025610180 scopus 로고
    • Effect of carvedilol on renal hemodynamics and renal excretory function in spontaneously hypertensive rats
    • Gellai, M., DeWolf, R., Ruffolo, R.R. Jr. Effect of carvedilol on renal hemodynamics and renal excretory function in spontaneously hypertensive rats. Pharmacology 1990, 41: 200-6.
    • (1990) Pharmacology , vol.41 , pp. 200-206
    • Gellai, M.1    DeWolf, R.2    Ruffolo Jr., R.R.3
  • 27
    • 0026754564 scopus 로고
    • Carvedilol: A novel cardiovascular drug with multiple actions
    • Ruffolo, R.R., Boyle, D.A., Brooks, D.P. et al. Carvedilol: A novel cardiovascular drug with multiple actions. Cardiovasc Drug Rev 1992, 10(2): 127-57.
    • (1992) Cardiovasc Drug Rev , vol.10 , Issue.2 , pp. 127-157
    • Ruffolo, R.R.1    Boyle, D.A.2    Brooks, D.P.3
  • 28
    • 0342680277 scopus 로고
    • Ar-rhythmia in patients with cardiomyopathy and congestive heart failure
    • Hosenpund, J.D., Greenberg, B.A. (Eds.). Springer Verlag: New York
    • Podrid, P.J., Fogel, R.I., Tordjman-Fuchs, T. Ar-rhythmia in patients with cardiomyopathy and congestive heart failure. In: Congestive Heart Failure. Hosenpund, J.D., Greenberg, B.A. (Eds.). Springer Verlag: New York 1994, 645-86.
    • (1994) Congestive Heart Failure , pp. 645-686
    • Podrid, P.J.1    Fogel, R.I.2    Tordjman-Fuchs, T.3
  • 29
    • 0029008519 scopus 로고
    • Antiarrhythmic effects of carvedilol in rat isolated heart subjected to regional ischemia and reperfusion
    • Bril, A., Tomasi, V., Laville, M.P. Antiarrhythmic effects of carvedilol in rat isolated heart subjected to regional ischemia and reperfusion. Pharmacol Commun 1995, 5: 291-300.
    • (1995) Pharmacol Commun , vol.5 , pp. 291-300
    • Bril, A.1    Tomasi, V.2    Laville, M.P.3
  • 30
    • 0030600527 scopus 로고    scopus 로고
    • Carvedilol improves function and reduces infarct size in the feline myocardium by protecting against lethal reperfusion injury
    • Brunvand, H., Froyland, L., Hexeberg, E., Rynning, S.E., Berge, R.K., Grong, K. Carvedilol improves function and reduces infarct size in the feline myocardium by protecting against lethal reperfusion injury. Eur J Pharmacol 1996, 314: 99-107.
    • (1996) Eur J Pharmacol , vol.314 , pp. 99-107
    • Brunvand, H.1    Froyland, L.2    Hexeberg, E.3    Rynning, S.E.4    Berge, R.K.5    Grong, K.6
  • 31
    • 0029824704 scopus 로고    scopus 로고
    • Carvedilol protects against lethal reperfusion injury through antiadrenergic mechanisms
    • Brunvand, H., Kvitting, P., Rynning, S.E., Berge, R.K., Grong, K. Carvedilol protects against lethal reperfusion injury through antiadrenergic mechanisms. J Cardiovasc Pharmacol 1996, 28: 409-17.
    • (1996) J Cardiovasc Pharmacol , vol.28 , pp. 409-417
    • Brunvand, H.1    Kvitting, P.2    Rynning, S.E.3    Berge, R.K.4    Grong, K.5
  • 32
    • 0026779879 scopus 로고
    • Carvedilol, a new vasodilator and beta-adrenoceptor antagonist, is an antioxidant and free radical scavenger
    • Yue, T-L., Cheng, H.Y., Lysko, P.G. et al. Carvedilol, a new vasodilator and beta-adrenoceptor antagonist, is an antioxidant and free radical scavenger. J Pharmacol Exp Ther 1992, 263(1): 92-8.
    • (1992) J Pharmacol Exp Ther , vol.263 , Issue.1 , pp. 92-98
    • Yue, T.-L.1    Cheng, H.Y.2    Lysko, P.G.3
  • 33
    • 0002881583 scopus 로고
    • Carvedilol: A new vasodilator and β-adrenoceptor antagonist, inhibits oxygen-radical-mediated lipid peroxidation in swine ventricular membranes
    • Yue, T-L., Liu, T., Feuerstein, G. Carvedilol: A new vasodilator and β-adrenoceptor antagonist, inhibits oxygen-radical-mediated lipid peroxidation in swine ventricular membranes. Pharmacol Commun 1992, 1(1): 27-35.
    • (1992) Pharmacol Commun , vol.1 , Issue.1 , pp. 27-35
    • Yue, T.-L.1    Liu, T.2    Feuerstein, G.3
  • 34
    • 0027441853 scopus 로고
    • Carvedilol, a new antihypertensive agent, prevents lipid peroxidation and oxidative injury to endothelial cells
    • Yue, T-L., McKenna, P.J., Gu, J.L., Cheng, H.Y., Ruffolo, R.R. Jr., Feuerstein, G.Z. Carvedilol, a new antihypertensive agent, prevents lipid peroxidation and oxidative injury to endothelial cells. Hypertension 1993, 22: 922-8.
    • (1993) Hypertension , vol.22 , pp. 922-928
    • Yue, T.-L.1    McKenna, P.J.2    Gu, J.L.3    Cheng, H.Y.4    Ruffolo Jr., R.R.5    Feuerstein, G.Z.6
  • 35
    • 0029004913 scopus 로고
    • Carvedilol, a new vasodilating beta-adrenoceptor blocker, inhibits oxidation of low density lipoproteins by vascular smooth muscle cells and prevents leukocyte adhesion to smooth muscle cells
    • Yue, T-L., Wang, X., Gu, J-L., Ruffolo, R.R. Jr., Feuerstein, G. Carvedilol, a new vasodilating beta-adrenoceptor blocker, inhibits oxidation of low density lipoproteins by vascular smooth muscle cells and prevents leukocyte adhesion to smooth muscle cells. J Pharmacol Exp Ther 1995, 273(3): 1442-9.
    • (1995) J Pharmacol Exp Ther , vol.273 , Issue.3 , pp. 1442-1449
    • Yue, T.-L.1    Wang, X.2    Gu, J.-L.3    Ruffolo Jr., R.R.4    Feuerstein, G.5
  • 36
    • 0026533584 scopus 로고
    • Carvedilol, a new β-adrenoceptor antagonist and vasodilator antihypertensive drug, inhibits superoxide release from human neutrophils
    • Yue, T-L., McKenna, P.J., Ruffolo, R.R. Jr., Feuerstein, G.Z. Carvedilol, a new β-adrenoceptor antagonist and vasodilator antihypertensive drug, inhibits superoxide release from human neutrophils. Eur J Pharmacol 1992, 214: 277-80.
    • (1992) Eur J Pharmacol , vol.214 , pp. 277-280
    • Yue, T.-L.1    McKenna, P.J.2    Ruffolo Jr., R.R.3    Feuerstein, G.Z.4
  • 37
    • 0028597944 scopus 로고
    • Carvedilol: A novel multiple action antihypertensive drug that provides major organ protection
    • Feuerstein, R., Yue, T.L. Carvedilol: A novel multiple action antihypertensive drug that provides major organ protection. Cardiovasc Drug Rev 1994, 12(2): 85-104.
    • (1994) Cardiovasc Drug Rev , vol.12 , Issue.2 , pp. 85-104
    • Feuerstein, R.1    Yue, T.L.2
  • 38
    • 0028096079 scopus 로고
    • SB 211475, a metabolite of carvedilol, a novel anti-hypertensive agent, is a potent antioxidant
    • Yue, T-L., McKenna, P.J., Lysko, P.G. et al. SB 211475, a metabolite of carvedilol, a novel anti-hypertensive agent, is a potent antioxidant. Eur J Pharmacol 1994, 251: 237-43.
    • (1994) Eur J Pharmacol , vol.251 , pp. 237-243
    • Yue, T.-L.1    McKenna, P.J.2    Lysko, P.G.3
  • 39
    • 85047677942 scopus 로고
    • Carvedilol, a new vasodilating β-adrenoceptor blocker antihypertensive drug, protects endothelial cells from damage initiated by xanthine-xanthine oxidase and neutrophils
    • Yue, T-L., McKenna, P.J., Gu, J.L., Cheng, H.Y., Ruffolo, R.R. Jr., Feuerstein, G.Z. Carvedilol, a new vasodilating β-adrenoceptor blocker antihypertensive drug, protects endothelial cells from damage initiated by xanthine-xanthine oxidase and neutrophils. Cardiol Res 1994, 28: 400-6.
    • (1994) Cardiol Res , vol.28 , pp. 400-406
    • Yue, T.-L.1    McKenna, P.J.2    Gu, J.L.3    Cheng, H.Y.4    Ruffolo Jr., R.R.5    Feuerstein, G.Z.6
  • 40
    • 0026470908 scopus 로고
    • Neuroprotective effects of carvedilol, a new antihypertensive agent, in cultured rat cerebellar neurons and in gerbil global brain ischemia
    • Lysko, P.G., Lysko, K.A., Yue, T-L., Webb, C.L., Gu, J-L., Feuerstein, G. Neuroprotective effects of carvedilol, a new antihypertensive agent, in cultured rat cerebellar neurons and in gerbil global brain ischemia. Stroke 1992, 23: 1630-6.
    • (1992) Stroke , vol.23 , pp. 1630-1636
    • Lysko, P.G.1    Lysko, K.A.2    Yue, T.-L.3    Webb, C.L.4    Gu, J.-L.5    Feuerstein, G.6
  • 41
    • 0002546322 scopus 로고
    • Carvedilol: A novel multiple action antihypertensive drug (Technical Review)
    • Lysko, P.G., Feuerstein, G.Z., Ruffolo, R.R. Jr. Carvedilol: A novel multiple action antihypertensive drug (Technical Review). Pharm News 1995, 2(3): 12-6.
    • (1995) Pharm News , vol.2 , Issue.3 , pp. 12-16
    • Lysko, P.G.1    Feuerstein, G.Z.2    Ruffolo Jr., R.R.3
  • 42
    • 0028914187 scopus 로고
    • Carvedilol, a new β-adrenoreceptor blocker, vasodilator and free radical scavenger, exerts an anti-shock and endothelial protective effect in rat splanchnic ischemia and reperfusion
    • Christopher, T.A., Yue, T-L., Feuerstein, G.Z., Ruffolo, R.R. Jr., Lopez, B.L., Ma, X-L. Carvedilol, a new β-adrenoreceptor blocker, vasodilator and free radical scavenger, exerts an anti-shock and endothelial protective effect in rat splanchnic ischemia and reperfusion. J Pharmacol Exp Ther 1995, 273: 64-71.
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 64-71
    • Christopher, T.A.1    Yue, T.-L.2    Feuerstein, G.Z.3    Ruffolo Jr., R.R.4    Lopez, B.L.5    Ma, X.-L.6
  • 43
    • 0029092047 scopus 로고
    • Carvedilol, a new β-adrenoceptor blocker antihypertensive drug, protects against free radical-induced endothelial dysfunction
    • Lopez, B.L., Christopher, T.A., Yue, T-L., Feuerstein, G.Z., Ma, X-L., Ruffolo, R.R. Jr. Carvedilol, a new β-adrenoceptor blocker antihypertensive drug, protects against free radical-induced endothelial dysfunction. Pharmacology 1995, 51: 165-73.
    • (1995) Pharmacology , vol.51 , pp. 165-173
    • Lopez, B.L.1    Christopher, T.A.2    Yue, T.-L.3    Feuerstein, G.Z.4    Ma, X.-L.5    Ruffolo Jr., R.R.6
  • 44
    • 0030918339 scopus 로고    scopus 로고
    • Hypercholesterolemia impairs a detoxification mechanism against peroxynitrite and renders the vascular tissue more susceptible to oxidative injury
    • Ma, X.L., Lopez, B.L., Liu, G-L. et al. Hypercholesterolemia impairs a detoxification mechanism against peroxynitrite and renders the vascular tissue more susceptible to oxidative injury. Circ Res 1997, 80: 894-901.
    • (1997) Circ Res , vol.80 , pp. 894-901
    • Ma, X.L.1    Lopez, B.L.2    Liu, G.-L.3
  • 45
    • 0029960787 scopus 로고    scopus 로고
    • Protective effect of carvedilol, a vasodilating β-adrenoceptor blocker, against in vivo low density lipoprotein oxidation in essential hypertension
    • Maggi, E., Marchesi, E., Covini, D., Negro, C., Perani, G., Bellomo, G. Protective effect of carvedilol, a vasodilating β-adrenoceptor blocker, against in vivo low density lipoprotein oxidation in essential hypertension. J Cardiovasc Pharmacol 1996, 27: 532-8.
    • (1996) J Cardiovasc Pharmacol , vol.27 , pp. 532-538
    • Maggi, E.1    Marchesi, E.2    Covini, D.3    Negro, C.4    Perani, G.5    Bellomo, G.6
  • 46
    • 0029907656 scopus 로고    scopus 로고
    • A hydroxylated analog of the β-adrenoceptor antagonist, carvedilol, affords exceptional antioxidant protection to postischemic rat hearts
    • Kramer, J.H., Weglicki, W.B. A hydroxylated analog of the β-adrenoceptor antagonist, carvedilol, affords exceptional antioxidant protection to postischemic rat hearts. Free Radic Biol Med 1996, 21: 813-25.
    • (1996) Free Radic Biol Med , vol.21 , pp. 813-825
    • Kramer, J.H.1    Weglicki, W.B.2
  • 48
    • 0024209856 scopus 로고
    • Myocardial neutrophil accumulation during reperfusion after reversible or irreversible ischemic injury
    • Go, L.O., Murray, C.E., Richard, V.J., Weischedel, G.R., Jennings, R.B., Reimer, K.A. Myocardial neutrophil accumulation during reperfusion after reversible or irreversible ischemic injury. Am J Physiol 1988, 255: H1188-98.
    • (1988) Am J Physiol , vol.255
    • Go, L.O.1    Murray, C.E.2    Richard, V.J.3    Weischedel, G.R.4    Jennings, R.B.5    Reimer, K.A.6
  • 49
    • 0024521203 scopus 로고
    • Reduction of myocardial damage and polymor-phonuclear leukocyte accumulation following coronary artery occlusion and reperfusion by the thromboxane receptor antagonist, BM 13.505
    • Smith, E.F., Griswold, D.E., Egan, J.W., Hillegass, L.M., DiMartino, M.J. Reduction of myocardial damage and polymor-phonuclear leukocyte accumulation following coronary artery occlusion and reperfusion by the thromboxane receptor antagonist, BM 13.505. J Cardiovasc Pharmacol 1989, 13: 715-22.
    • (1989) J Cardiovasc Pharmacol , vol.13 , pp. 715-722
    • Smith, E.F.1    Griswold, D.E.2    Egan, J.W.3    Hillegass, L.M.4    DiMartino, M.J.5
  • 50
    • 85047678019 scopus 로고
    • Cardioprotective effects of carvedilol, a novel β-adrenoceptor antagonist with vasodilating properties, in anaesthetised minipigs: Comparison with propranolol
    • Bril, A., Slivjak, M., DiMartino, J. et al. Cardioprotective effects of carvedilol, a novel β-adrenoceptor antagonist with vasodilating properties, in anaesthetised minipigs: Comparison with propranolol. Cardiovasc Res 1992, 26: 518-25.
    • (1992) Cardiovasc Res , vol.26 , pp. 518-525
    • Bril, A.1    Slivjak, M.2    DiMartino, J.3
  • 51
    • 0030430050 scopus 로고    scopus 로고
    • Carvedilol, a new β-adrenoreceptor blocker and free radical scavenger, attenuates myocardial ischemia reperfusion injury in hypercholesterolemic rabbits
    • Ma, X-L., Yue, T-L., Lopez, B.L. et al. Carvedilol, a new β-adrenoreceptor blocker and free radical scavenger, attenuates myocardial ischemia reperfusion injury in hypercholesterolemic rabbits. J Pharmacol Exp Ther 1996, 277(1): 128-36.
    • (1996) J Pharmacol Exp Ther , vol.277 , Issue.1 , pp. 128-136
    • Ma, X.-L.1    Yue, T.-L.2    Lopez, B.L.3
  • 52
    • 0026754564 scopus 로고
    • Carvedilol: A novel cardiovascular drug with multiple actions
    • Ruffolo, R.R., Boyle, D.A., Brooks, D.P. et al. Carvedilol: A novel cardiovascular drug with multiple actions. Cardiovasc Drug Rev 1992, 10(2): 127-57.
    • (1992) Cardiovasc Drug Rev , vol.10 , Issue.2 , pp. 127-157
    • Ruffolo, R.R.1    Boyle, D.A.2    Brooks, D.P.3
  • 54
    • 0029145195 scopus 로고
    • Carvedilol update III: Rationale for use in congestive heart failure
    • Feuerstein, G.Z., Poste, G., Ruffolo, R.R. Carvedilol update III: Rationale for use in congestive heart failure. Drugs Today 1995, 31: 307-26.
    • (1995) Drugs Today , vol.31 , pp. 307-326
    • Feuerstein, G.Z.1    Poste, G.2    Ruffolo, R.R.3
  • 55
    • 0028150796 scopus 로고
    • Comparison of the ability of two vasodilating β-blockers, carvedilol and celiprolol to reduce infarct size in a pig model of acute myocardial infarction
    • Feuerstein, G.Z., Ruffolo, R.R. Jr. Comparison of the ability of two vasodilating β-blockers, carvedilol and celiprolol to reduce infarct size in a pig model of acute myocardial infarction. Pharmacol Commun 1994, 5: 57-63.
    • (1994) Pharmacol Commun , vol.5 , pp. 57-63
    • Feuerstein, G.Z.1    Ruffolo Jr., R.R.2
  • 56
    • 84878713298 scopus 로고    scopus 로고
    • A hydroxylated metabolite of the β-adrenoceptor antagonist, carvedilol, attenuates post-ischemic splanchnic tissue injury
    • in press
    • Christopher, T., Lopez, B., Feuerstein, G., Ruffolo, R.R. Jr., Ma, X-L., Yue, T-L. A hydroxylated metabolite of the β-adrenoceptor antagonist, carvedilol, attenuates post-ischemic splanchnic tissue injury. Am J Physiol, in press.
    • Am J Physiol
    • Christopher, T.1    Lopez, B.2    Feuerstein, G.3    Ruffolo Jr., R.R.4    Ma, X.-L.5    Yue, T.-L.6
  • 59
    • 0023898232 scopus 로고
    • Cardiac involvement in hypertension
    • DiPette, D.J., Frohlich, E.D. Cardiac involvement in hypertension. Am J Cardiol 1988, 61: 40-6.
    • (1988) Am J Cardiol , vol.61 , pp. 40-46
    • DiPette, D.J.1    Frohlich, E.D.2
  • 61
    • 0028269556 scopus 로고
    • Carvedilol, a novel cardiovascular agent, inhibits development of vascular and ventricular hypertrophy in spontaneously hypertensive rats
    • Ohlstein, E.H., Vickery, L., Arleth, A. et al. Carvedilol, a novel cardiovascular agent, inhibits development of vascular and ventricular hypertrophy in spontaneously hypertensive rats. Clin Exp Hypertens 1994, 16: 163-77.
    • (1994) Clin Exp Hypertens , vol.16 , pp. 163-177
    • Ohlstein, E.H.1    Vickery, L.2    Arleth, A.3
  • 62
    • 0030426904 scopus 로고    scopus 로고
    • Chronic carvedilol and propranolol reduces mortality and renal damage in hypertensive stroke-prone rats
    • Barone, F.C., Nelson, A.H., Ohlstein, E.H. et al. Chronic carvedilol and propranolol reduces mortality and renal damage in hypertensive stroke-prone rats. J Pharmacol Exp Ther 1996, 279: 948-55.
    • (1996) J Pharmacol Exp Ther , vol.279 , pp. 948-955
    • Barone, F.C.1    Nelson, A.H.2    Ohlstein, E.H.3
  • 63
    • 84878725374 scopus 로고    scopus 로고
    • Carvedilol prevents severe hypertension induced cardiomyopathy and remodeling
    • in review
    • Barone, F.C., Campbell, W.G., Nelson, A.H., Feuerstein, G.Z. Carvedilol prevents severe hypertension induced cardiomyopathy and remodeling. J Hypertens 1997, in review.
    • (1997) J Hypertens
    • Barone, F.C.1    Campbell, W.G.2    Nelson, A.H.3    Feuerstein, G.Z.4
  • 64
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide ranging implications in tissue kinetics
    • Kerr, J.F.R., Wyllie, A.H., Currie, A.R. Apoptosis: A basic biological phenomenon with wide ranging implications in tissue kinetics. Br J Cancer 1992, 26: 239-57.
    • (1992) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 65
    • 10244254975 scopus 로고    scopus 로고
    • Apoptosis in myocytes in end stage heart failure
    • Narula, J., Haider, N., Virmani, R. et al. Apoptosis in myocytes in end stage heart failure. New Engl J Med 1996, 335: 1182-9.
    • (1996) New Engl J Med , vol.335 , pp. 1182-1189
    • Narula, J.1    Haider, N.2    Virmani, R.3
  • 68
    • 84878728523 scopus 로고    scopus 로고
    • Involvement of stress activated protein kinase signaling pathway and Fas receptor expression in prevention of ischemia/ reperfusion induced myocyte apoptosis by carvedilol
    • in press
    • Yue, T-L., Ma, X-L., Romanic, A.M. et al. Involvement of stress activated protein kinase signaling pathway and Fas receptor expression in prevention of ischemia/ reperfusion induced myocyte apoptosis by carvedilol. Circ Res 1997, in press.
    • (1997) Circ Res
    • Yue, T.-L.1    Ma, X.-L.2    Romanic, A.M.3
  • 69
    • 0030979773 scopus 로고    scopus 로고
    • Double identity for proteins of Bcl-2 family
    • Reed, J.C. Double identity for proteins of Bcl-2 family. Science 1997, 387: 773-6.
    • (1997) Science , vol.387 , pp. 773-776
    • Reed, J.C.1
  • 71
    • 0025739254 scopus 로고
    • Reactive oxygen intermediates as apparently widely used second messengers in the activation of NF-xB transcription factor and HIV-1
    • Schreck, R., Reiber, P., Baeccerle, P.A. Reactive oxygen intermediates as apparently widely used second messengers in the activation of NF-xB transcription factor and HIV-1. EMBO J 1991, 10: 2247-58.
    • (1991) EMBO J , vol.10 , pp. 2247-2258
    • Schreck, R.1    Reiber, P.2    Baeccerle, P.A.3
  • 73
    • 0023638237 scopus 로고
    • Effect of carvedilol on ambulatory blood pressure, renal hemodynamics and cardiac function in essential hypertension
    • Dupont, A.G., Vander-Nieran, P., Tallymaloney, Y. Effect of carvedilol on ambulatory blood pressure, renal hemodynamics and cardiac function in essential hypertension. J Cardiovasc Pharmacol 1987, Suppl. 11: 5130-6.
    • (1987) J Cardiovasc Pharmacol , Issue.11 SUPPL. , pp. 5130-5136
    • Dupont, A.G.1    Vander-Nieran, P.2    Tallymaloney, Y.3
  • 74
    • 0345513198 scopus 로고
    • Changes in plasma levels of endothelin reflect the long term clinical and hemodynamic effects of beta-blockade in patients with chronic heart failure
    • Krum, H.G., Wilshire-Clement, M., Miller, M., Medina, N., Yushak, M., Packer, M. Changes in plasma levels of endothelin reflect the long term clinical and hemodynamic effects of beta-blockade in patients with chronic heart failure. J Am Coll Cardiol 1994, 172A.
    • (1994) J Am Coll Cardiol
    • Krum, H.G.1    Wilshire-Clement, M.2    Miller, M.3    Medina, N.4    Yushak, M.5    Packer, M.6
  • 75
    • 84878745225 scopus 로고    scopus 로고
    • Carvedilol inhibits endothetin-1 biosynthesis in cultured human coronary artery endothelial cell
    • in review
    • Ohlstein, E.H., Arleth, A.J., Storer, B., Romanic, A.M. Carvedilol inhibits endothetin-1 biosynthesis in cultured human coronary artery endothelial cell. J Mol Cell Cardiol 1997, in review.
    • (1997) J Mol Cell Cardiol
    • Ohlstein, E.H.1    Arleth, A.J.2    Storer, B.3    Romanic, A.M.4
  • 76
    • 0027163945 scopus 로고
    • Carvedilol, a novel cardiovascular drug prevents vascular smooth muscle proliferation, migration and neointima formation following vascular injury
    • Ohlstein, E.H., Douglas, S.A., Sung, C-P. et al. Carvedilol, a novel cardiovascular drug prevents vascular smooth muscle proliferation, migration and neointima formation following vascular injury. Proc Natl Acad Sci 1993, 90: 6189-93.
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 6189-6193
    • Ohlstein, E.H.1    Douglas, S.A.2    Sung, C.-P.3
  • 77
    • 0030453430 scopus 로고    scopus 로고
    • Tumor necrosis factor-α induced apoptosis in cardiac myocytes
    • Krown, K.A., Page, M.T., Nguyen, C. et al. Tumor necrosis factor-α induced apoptosis in cardiac myocytes. J Clin Invest 1996, 98: 2854-65.
    • (1996) J Clin Invest , vol.98 , pp. 2854-2865
    • Krown, K.A.1    Page, M.T.2    Nguyen, C.3
  • 79
    • 0026772962 scopus 로고
    • Effect of carvedilol on left ventricle function and mass in hypertension
    • Why, H.J.F., Richardson, P.J. Effect of carvedilol on left ventricle function and mass in hypertension. J Cardiovasc Pharmacol 1992, 19(Suppl. 1): 550-4.
    • (1992) J Cardiovasc Pharmacol , vol.19 , Issue.1 SUPPL. , pp. 550-554
    • Why, H.J.F.1    Richardson, P.J.2
  • 80
    • 0030997947 scopus 로고    scopus 로고
    • Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease
    • Doughty, R.N., Whalley, G.A., Gamble, G., MacMahon, S., Sharpe, N. Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease. J Am Coll Cardiol 1997, 29: 1060-6.
    • (1997) J Am Coll Cardiol , vol.29 , pp. 1060-1066
    • Doughty, R.N.1    Whalley, G.A.2    Gamble, G.3    MacMahon, S.4    Sharpe, N.5
  • 81
    • 0029006613 scopus 로고
    • Effects of carvedilol, a vasodilator β-blocker, in patients with congestive heart failure due to ischemic heart disease
    • Australian-New Zealand Heart Failure Research Collaborative Group. Effects of carvedilol, a vasodilator β-blocker, in patients with congestive heart failure due to ischemic heart disease. Circulation 1995, 92: 212-8.
    • (1995) Circulation , vol.92 , pp. 212-218
  • 82
    • 0028947523 scopus 로고
    • Carvedilol improves left ventricular function and symptoms in chronic heart failure: A double-blind randomized study
    • Olsen, S.L., Gilbert, E.M., Renlund, D.G., Taylor, D.O., Yanowitz, F.D., Bristow, M.R. Carvedilol improves left ventricular function and symptoms in chronic heart failure: A double-blind randomized study. J Am Coll Cardiol 1995, 25: 1225-31.
    • (1995) J Am Coll Cardiol , vol.25 , pp. 1225-1231
    • Olsen, S.L.1    Gilbert, E.M.2    Renlund, D.G.3    Taylor, D.O.4    Yanowitz, F.D.5    Bristow, M.R.6
  • 83
    • 0029085811 scopus 로고
    • Double-blind, placebo-controlled study of the long-term efficacy of carvedilol in patients with severe chronic heart failure
    • Krum, H., Sackner-Bernstein, J.D., Goldsmith, R.L. et al. Double-blind, placebo-controlled study of the long-term efficacy of carvedilol in patients with severe chronic heart failure. Circulation 1995, 92: 1499-506.
    • (1995) Circulation , vol.92 , pp. 1499-1506
    • Krum, H.1    Sackner-Bernstein, J.D.2    Goldsmith, R.L.3
  • 84
    • 0028081393 scopus 로고
    • Effects of short-and long-term carvedilol administration on rest and exercise hemodynamic variables, exercise capacity and clinical conditions in patients with idiopathic dilated cardiomyopathy
    • Metra, M., Mardi, M., Giubbini, R., Cas, L.D. Effects of short-and long-term carvedilol administration on rest and exercise hemodynamic variables, exercise capacity and clinical conditions in patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol 1994; 24: 1678-87.
    • (1994) J Am Coll Cardiol , vol.24 , pp. 1678-1687
    • Metra, M.1    Mardi, M.2    Giubbini, R.3    Cas, L.D.4
  • 85
    • 0029937949 scopus 로고    scopus 로고
    • The effect of carvedilol on morbidity and mortality in patients with chronic heart failure
    • Packer, M., Bristow, M.R., Cohn, J.N. et al. The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. New Engl J Med 1996: 334: 1349-55.
    • (1996) New Engl J Med , vol.334 , pp. 1349-1355
    • Packer, M.1    Bristow, M.R.2    Cohn, J.N.3
  • 86
    • 0029006613 scopus 로고
    • Effects of carvedilol, a vasodilator β-blocker, in patients with congestive heart failure due to ischemic heart disease
    • Australia-New Zealand Heart Failure Research Collaborative Group. Effects of carvedilol, a vasodilator β-blocker, in patients with congestive heart failure due to ischemic heart disease. Circulation 1995, 92: 212-8.
    • (1995) Circulation , vol.92 , pp. 212-218
  • 87
    • 0031050642 scopus 로고    scopus 로고
    • Randomised, placebo-controlled trial of carvedilol in patients with congestive heart failure due to ischaemic heart disease
    • Australial-New Zealand Heart Failure Research Collaborative Group. Randomised, placebo-controlled trial of carvedilol in patients with congestive heart failure due to ischaemic heart disease. Lancet 1997, 349: 375-80.
    • (1997) Lancet , vol.349 , pp. 375-380
  • 88
    • 10544223267 scopus 로고    scopus 로고
    • Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure
    • for the MOCHA Investigators
    • Bristow, M.R., Gilbert, E.M., Abraham, W.T. et al. for the MOCHA Investigators. Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure. Circulation 1996, 94: 2807-16.
    • (1996) Circulation , vol.94 , pp. 2807-2816
    • Bristow, M.R.1    Gilbert, E.M.2    Abraham, W.T.3
  • 89
    • 10544251442 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study of the effects of carvedilol in patients with moderate to severe heart failure; the PRECISE trial
    • Packer, M., Colucci, W.S., Sackner-Bernstein, J. et al. Double-blind, placebo-controlled study of the effects of carvedilol in patients with moderate to severe heart failure; The PRECISE trial. Circulation 1996, 94: 2793-9.
    • (1996) Circulation , vol.94 , pp. 2793-2799
    • Packer, M.1    Colucci, W.S.2    Sackner-Bernstein, J.3
  • 90
    • 10544231452 scopus 로고    scopus 로고
    • Carvedilol inhibits clinical progression in patients with mild symptoms of heart failure
    • for the US Carvedilol Heart Failure Study Group
    • Colucci, W.S., Packer, M., Bristow, M.R. et al. for the US Carvedilol Heart Failure Study Group. Carvedilol inhibits clinical progression in patients with mild symptoms of heart failure. Circulation 1996, 94: 2800-6.
    • (1996) Circulation , vol.94 , pp. 2800-2806
    • Colucci, W.S.1    Packer, M.2    Bristow, M.R.3
  • 91
    • 0000987062 scopus 로고    scopus 로고
    • Effect of carvedilol in severe chronic heart failure
    • Abst
    • Cohn, J.N., Fowler, M.B., Bristow, M.A. et al. Effect of carvedilol in severe chronic heart failure. J Am Coll Cardiol 1996, 27(Suppl. A): Abst 169A.
    • (1996) J Am Coll Cardiol , vol.27 , Issue.SUPPL. A
    • Cohn, J.N.1    Fowler, M.B.2    Bristow, M.A.3
  • 92
    • 0026785561 scopus 로고
    • Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions
    • SOLVD Investigators. Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. New Engl J Med 1992, 327: 685-91.
    • (1992) New Engl J Med , vol.327 , pp. 685-691
  • 93
    • 0027322458 scopus 로고
    • Effects of vesnarinone on morbidity and mortality in patients with heart failure
    • Feldman, A.M., Bristow, M.R., Parmley, W.W. et al. Effects of vesnarinone on morbidity and mortality in patients with heart failure. New Engl J Med 1993, 329: 149-55.
    • (1993) New Engl J Med , vol.329 , pp. 149-155
    • Feldman, A.M.1    Bristow, M.R.2    Parmley, W.W.3


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