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Volumn 28, Issue 3, 1996, Pages 409-417

Carvedilol protects against lethal reperfusion injury through antiadrenergic mechanisms

Author keywords

Adrenergic receptor blockade; Carvedilol; Myocardial ischemia; Reperfusion injury

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ANTIOXIDANT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARVEDILOL; DOXAZOSIN; PROPRANOLOL;

EID: 0029824704     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199609000-00010     Document Type: Article
Times cited : (29)

References (38)
  • 1
    • 0027769607 scopus 로고
    • Reperfusion in acute myocardial infarction: Effect of timing and modulating factors in experimental models
    • Reimer KA, Vander Heide RS, Richard VJ. Reperfusion in acute myocardial infarction: effect of timing and modulating factors in experimental models. Am J Cardiol 1993;72: 13G-21G.
    • (1993) Am J Cardiol , vol.72
    • Reimer, K.A.1    Vander Heide, R.S.2    Richard, V.J.3
  • 2
    • 0023192195 scopus 로고
    • Myocardial consequences of reperfusion
    • Becker LC, Ambrosio G. Myocardial consequences of reperfusion. Prog Cardiovasc Dis 1987;30:23-44.
    • (1987) Prog Cardiovasc Dis , vol.30 , pp. 23-44
    • Becker, L.C.1    Ambrosio, G.2
  • 3
    • 0023268486 scopus 로고
    • Free radical and myocardial ischemia and reperfusion injury
    • Simpson PJ, Lucchesi BR. Free radical and myocardial ischemia and reperfusion injury. J Lab Clin Med 1987;110: 13-30.
    • (1987) J Lab Clin Med , vol.110 , pp. 13-30
    • Simpson, P.J.1    Lucchesi, B.R.2
  • 4
    • 0024519434 scopus 로고
    • Can Superoxide dismutase alter myocardial infarct size?
    • Engler R, Gilpin E. Can Superoxide dismutase alter myocardial infarct size? Circulation 1989;79:1137-42.
    • (1989) Circulation , vol.79 , pp. 1137-1142
    • Engler, R.1    Gilpin, E.2
  • 5
    • 0027403741 scopus 로고
    • Does reperfusion injury exist in humans?
    • Kloner RA. Does reperfusion injury exist in humans? J Am Coll Cardiol 1993;21:537-45.
    • (1993) J Am Coll Cardiol , vol.21 , pp. 537-545
    • Kloner, R.A.1
  • 6
    • 0029061101 scopus 로고
    • Absence of lethal reperfusion injury after 3 hours of reperfusion: A study in a single-canine-heart model of ischemia-reperfusion
    • Zahger D, Yano J, Chaux A, Fishbein MC, Ganz W. Absence of lethal reperfusion injury after 3 hours of reperfusion: a study in a single-canine-heart model of ischemia-reperfusion. Circulation 1995;91:2989-94.
    • (1995) Circulation , vol.91 , pp. 2989-2994
    • Zahger, D.1    Yano, J.2    Chaux, A.3    Fishbein, M.C.4    Ganz, W.5
  • 7
    • 0025760521 scopus 로고
    • Oxygen-derived free radicals and myocardial reperfusion injury: An overview
    • Bolli R. Oxygen-derived free radicals and myocardial reperfusion injury: an overview, Cardiovasc Drugs Ther 1991;5: 249-68.
    • (1991) Cardiovasc Drugs Ther , vol.5 , pp. 249-268
    • Bolli, R.1
  • 8
    • 0025309190 scopus 로고
    • Protection of the myocardium during myocardial infarction: Pharmacologic protection during thrombolytic therapy
    • Willerson JT, Buja M. Protection of the myocardium during myocardial infarction: pharmacologic protection during thrombolytic therapy. Am J Cardiol 1990;65:351-411.
    • (1990) Am J Cardiol , vol.65 , pp. 351-411
    • Willerson, J.T.1    Buja, M.2
  • 9
    • 0028196994 scopus 로고
    • Myocardial reperfusion injury: Role of oxygen radicals and potential therapy with antioxidants
    • Jeroudi MO, Hartley CJ, Bolli R. Myocardial reperfusion injury: role of oxygen radicals and potential therapy with antioxidants. Am J Cardiol 1994;73:2B-7B.
    • (1994) Am J Cardiol , vol.73
    • Jeroudi, M.O.1    Hartley, C.J.2    Bolli, R.3
  • 10
    • 0028102219 scopus 로고
    • Regional contractile blockade at the onset of reperfusion reduces infarct size in the dog heart
    • Schlack W, Uebing A, Schäfer M, et al. Regional contractile blockade at the onset of reperfusion reduces infarct size in the dog heart. Pflugers Arch 1994;428:134-41.
    • (1994) Pflugers Arch , vol.428 , pp. 134-141
    • Schlack, W.1    Uebing, A.2    Schäfer, M.3
  • 11
    • 0028920535 scopus 로고
    • Intracoronary SINIC during reperfusion reduces infarct size in dog
    • Schlack W, Uebing A, Schäfer M. et al. Intracoronary SINIC during reperfusion reduces infarct size in dog. J Cardiovasc Pharmacol 1995;25:424-31.
    • (1995) J Cardiovasc Pharmacol , vol.25 , pp. 424-431
    • Schlack, W.1    Uebing, A.2    Schäfer, M.3
  • 12
    • 0026017380 scopus 로고
    • Reduction of myocardial reperfusion injury by intravenous adenosine administered during the early reperfusion period
    • Pitarys II CJ, Virmani R, Vildibill HD Jr, Jackson EK, Forman MB. Reduction of myocardial reperfusion injury by intravenous adenosine administered during the early reperfusion period. Circulation 1991;83:237-47.
    • (1991) Circulation , vol.83 , pp. 237-247
    • Pitarys II, C.J.1    Virmani, R.2    Vildibill Jr., H.D.3    Jackson, E.K.4    Forman, M.B.5
  • 13
    • 0024787759 scopus 로고
    • Neutrophil depletion limited to reperfusion reduces myocardial infarct size after 90 minutes of ischemia. Evidence for neutrophil-mediated reperfusion injury
    • Litt MR, Jeremy RW, Weisman HF, Winkelstein JA, Becker LC. Neutrophil depletion limited to reperfusion reduces myocardial infarct size after 90 minutes of ischemia. Evidence for neutrophil-mediated reperfusion injury. Circulation 1989;80:1816-27.
    • (1989) Circulation , vol.80 , pp. 1816-1827
    • Litt, M.R.1    Jeremy, R.W.2    Weisman, H.F.3    Winkelstein, J.A.4    Becker, L.C.5
  • 14
    • 0026332850 scopus 로고
    • 1-adrenergic system and arrhythmias in ischemic heart disease
    • 1-adrenergic system and arrhythmias in ischemic heart disease. Eur Heart J 1991;12(suppl F):88-98.
    • (1991) Eur Heart J , vol.12 , Issue.SUPPL. F , pp. 88-98
    • Kurz, T.1    Yamada, K.A.2    DaTorre, S.D.3    Corr, P.B.4
  • 15
    • 0024841997 scopus 로고
    • In vitro pharmacologic profile of the novel beta-adrenoceptor antagonist and vasodilator, carvedilol
    • Nichols AJ, Sulpizio AC, Ashton DJ, Hieble JP, Ruffolo RR Jr. In vitro pharmacologic profile of the novel beta-adrenoceptor antagonist and vasodilator, carvedilol. Pharmacology 1989;39:327-36.
    • (1989) Pharmacology , vol.39 , pp. 327-336
    • Nichols, A.J.1    Sulpizio, A.C.2    Ashton, D.J.3    Hieble, J.P.4    Ruffolo Jr., R.R.5
  • 17
    • 0025755383 scopus 로고
    • Studies on the mechanism of arterial vasodilation produced by the novel antihypertensive agent, carvedilol
    • Nichols AJ, Gellai M, Ruffolo RR Jr. Studies on the mechanism of arterial vasodilation produced by the novel antihypertensive agent, carvedilol. Fund Clin Pharmacol 1991;5: 25-38.
    • (1991) Fund Clin Pharmacol , vol.5 , pp. 25-38
    • Nichols, A.J.1    Gellai, M.2    Ruffolo Jr., R.R.3
  • 18
    • 0002881583 scopus 로고
    • Carvedilol, a new vasodilator and β-adrenoceptor antagonist, inhibits oxygen-radical-mediated lipid peroxidation in swine ventricular membranes
    • Yue TL, Liu T, Feuerstein GZ. Carvedilol, a new vasodilator and β-adrenoceptor antagonist, inhibits oxygen-radical-mediated lipid peroxidation in swine ventricular membranes. Pharmacol Commun 1992;1:27-35.
    • (1992) Pharmacol Commun , vol.1 , pp. 27-35
    • Yue, T.L.1    Liu, T.2    Feuerstein, G.Z.3
  • 19
    • 0027267491 scopus 로고
    • Myocardial protection by the novel vasodilating beta-blocker, carvedilol: Potential relevance of anti-oxidant activity
    • Feuerstein GZ, Yue TL, Cheng HY, Ruffolo RR Jr. Myocardial protection by the novel vasodilating beta-blocker, carvedilol: potential relevance of anti-oxidant activity. J Hypertens 1993:11(suppl 4):S41-8.
    • (1993) J Hypertens , vol.11 , Issue.SUPPL. 4
    • Feuerstein, G.Z.1    Yue, T.L.2    Cheng, H.Y.3    Ruffolo Jr., R.R.4
  • 20
    • 0027441853 scopus 로고
    • Carvedilol, a new antihypertensive agent, prevents lipid peroxidation and oxidative injury to endothelial cells
    • Yue TL, Mckenna PJ, Gu JL, Cheng HY, Ruffolo RR Jr, Feuerstein GZ. Carvedilol, a new antihypertensive agent, prevents lipid peroxidation and oxidative injury to endothelial cells. Hypertension 1993;22:922-8.
    • (1993) Hypertension , vol.22 , pp. 922-928
    • Yue, T.L.1    Mckenna, P.J.2    Gu, J.L.3    Cheng, H.Y.4    Ruffolo Jr., R.R.5    Feuerstein, G.Z.6
  • 22
    • 0025917935 scopus 로고
    • Carvedilol (Kredex®) reduces infarct size in a canine model of acute myocardial infarction
    • Hamburger SA, Barone FC, Feuerstein GZ, Ruffolo RR Jr. Carvedilol (Kredex®) reduces infarct size in a canine model of acute myocardial infarction. Pharmacology 1991;43: 113-20.
    • (1991) Pharmacology , vol.43 , pp. 113-120
    • Hamburger, S.A.1    Barone, F.C.2    Feuerstein, G.Z.3    Ruffolo Jr., R.R.4
  • 23
    • 85047678019 scopus 로고
    • Cardioprotective effects of carvedilol, a novel β-adrenoceptor antagonist with vasodilating properties, in anaesthetised minipigs: Comparison with propranolol
    • Bril A, Slivjak M, DiMartino MJ, et al. Cardioprotective effects of carvedilol, a novel β-adrenoceptor antagonist with vasodilating properties, in anaesthetised minipigs: comparison with propranolol. Cardiovasc Res 1992;26:518-25.
    • (1992) Cardiovasc Res , vol.26 , pp. 518-525
    • Bril, A.1    Slivjak, M.2    Dimartino, M.J.3
  • 24
    • 0029152926 scopus 로고
    • Non-uniform recovery of segment shortening during reperfusion following regional myocardial ischemia despite uniform recovery of ATP
    • Brunvand H, Rynning SE, Hexeberg E, Westby J, Grong K. Non-uniform recovery of segment shortening during reperfusion following regional myocardial ischemia despite uniform recovery of ATP. Cardiovasc Res 1995;30:138-46.
    • (1995) Cardiovasc Res , vol.30 , pp. 138-146
    • Brunvand, H.1    Rynning, S.E.2    Hexeberg, E.3    Westby, J.4    Grong, K.5
  • 25
    • 0024459946 scopus 로고
    • Non-uniform shortening of the anterior wall of feline left ventricles
    • Hexeberg E, Matre K, Birkeland S, Lekven J. Non-uniform shortening of the anterior wall of feline left ventricles. Am J Physiol 1989;257:H1165-73.
    • (1989) Am J Physiol , vol.257
    • Hexeberg, E.1    Matre, K.2    Birkeland, S.3    Lekven, J.4
  • 26
    • 0025855314 scopus 로고
    • Transmural fiber direction in the anterior wall of the feline left ventricle; theoretical considerations with regard to uniformity of contraction
    • Hexeberg E, Matre K, Lekven J. Transmural fiber direction in the anterior wall of the feline left ventricle; theoretical considerations with regard to uniformity of contraction. Acta Physiol Scand 1991;141-.497-505.
    • (1991) Acta Physiol Scand , vol.141 , pp. 497-505
    • Hexeberg, E.1    Matre, K.2    Lekven, J.3
  • 27
    • 0024514679 scopus 로고
    • 1-adrenergic blockade influence regional blood flow regulation in hearts with coronary artery occlusion?
    • 1-adrenergic blockade influence regional blood flow regulation in hearts with coronary artery occlusion? Clin Physiol 1989;9:107-20.
    • (1989) Clin Physiol , vol.9 , pp. 107-120
    • Westby, J.1    Kvitting, P.2    Birkeland, S.3    Grong, K.4    Lekven, J.5
  • 28
    • 0025100797 scopus 로고
    • Determination of reduced, oxidized, and protein-bound glutathione in human plasma with precolumn derivatization with monobromobimane and liquid chromatography
    • Svardal AM, Mansoor MA, Ueland PM. Determination of reduced, oxidized, and protein-bound glutathione in human plasma with precolumn derivatization with monobromobimane and liquid chromatography. Anal Biochem 1990;184: 338-46.
    • (1990) Anal Biochem , vol.184 , pp. 338-346
    • Svardal, A.M.1    Mansoor, M.A.2    Ueland, P.M.3
  • 29
    • 0028009972 scopus 로고
    • An improved method for the measurement of malondialdehyde in biological samples
    • Li X-Y, Chow CK. An improved method for the measurement of malondialdehyde in biological samples. Lipids 1994; 29:73-5.
    • (1994) Lipids , vol.29 , pp. 73-75
    • Li, X.-Y.1    Chow, C.K.2
  • 31
    • 0019555664 scopus 로고
    • Maximal negative dP/dt as an indicator of end of systole
    • Abel FL. Maximal negative dP/dt as an indicator of end of systole. Am J Physiol 1981;240:H676-9.
    • (1981) Am J Physiol , vol.240
    • Abel, F.L.1
  • 32
    • 15444364985 scopus 로고
    • Adrenergic receptor and sensitization of adenylyl cyclase in acute myocardial ischemia
    • Strasser RH, Marquetant R, Kübler W. Adrenergic receptor and sensitization of adenylyl cyclase in acute myocardial ischemia. Circulation 1990;82(suppl II):1123-9.
    • (1990) Circulation , vol.82 , Issue.SUPPL. II , pp. 1123-1129
    • Strasser, R.H.1    Marquetant, R.2    Kübler, W.3
  • 33
    • 0026754564 scopus 로고
    • Carvedilol: A novel cardiovascular drug with multiple actions
    • Ruffolo RR Jr, Boyle DA, Brooks DP, et al. Carvedilol: a novel cardiovascular drug with multiple actions. Cardiovasc Drug Rev 1992;10:127-57.
    • (1992) Cardiovasc Drug Rev , vol.10 , pp. 127-157
    • Ruffolo Jr., R.R.1    Boyle, D.A.2    Brooks, D.P.3
  • 34
    • 0029021506 scopus 로고
    • Reperfusion at reduced flow rates enhances postischemic contractile recovery of perfused heart
    • Takeo S, Liu J-X, Tanonaka K, et al. Reperfusion at reduced flow rates enhances postischemic contractile recovery of perfused heart. Am J Physiol 1995;268:H2384-95.
    • (1995) Am J Physiol , vol.268
    • Takeo, S.1    Liu, J.-X.2    Tanonaka, K.3
  • 35
    • 0028887709 scopus 로고
    • Prevention of ischaemia-induced biochemical changes by curcumin & quinidine in the cat heart
    • Dikshit M, Rastogi L, Shukla R, Srimal RC. Prevention of ischaemia-induced biochemical changes by curcumin & quinidine in the cat heart. Indian J Med Res 1995;101:31-5.
    • (1995) Indian J Med Res , vol.101 , pp. 31-35
    • Dikshit, M.1    Rastogi, L.2    Shukla, R.3    Srimal, R.C.4
  • 36
    • 85047677469 scopus 로고
    • Compensatory subendocardial hyperkinesis in the cat is abolished during coronary insufficiency outside an acutely ischaemic region
    • Birkeland S, Westby J, Hessevik I, Grong K, Hexeberg E, Lekven J. Compensatory subendocardial hyperkinesis in the cat is abolished during coronary insufficiency outside an acutely ischaemic region. Cardiovasc Res 1992;26:285-91.
    • (1992) Cardiovasc Res , vol.26 , pp. 285-291
    • Birkeland, S.1    Westby, J.2    Hessevik, I.3    Grong, K.4    Hexeberg, E.5    Lekven, J.6
  • 37
    • 0026730219 scopus 로고
    • Compensatory regional contraction following coronary artery occlusion depends on subendocardial hyperaemia and hyperkinesis
    • Birkeland S, Westby J, Grong K, Hexeberg E, Lekven J. Compensatory regional contraction following coronary artery occlusion depends on subendocardial hyperaemia and hyperkinesis. Eur Heart J 1992;13:1207-16.
    • (1992) Eur Heart J , vol.13 , pp. 1207-1216
    • Birkeland, S.1    Westby, J.2    Grong, K.3    Hexeberg, E.4    Lekven, J.5
  • 38
    • 0026625618 scopus 로고
    • Coronary artery stenosis provokes non-uniformity of two-dimensional deformation in the anterior wall of the feline left ventricle
    • Hexeberg E, Birkeland S, Grong K, Matre K, Lekven J. Coronary artery stenosis provokes non-uniformity of two-dimensional deformation in the anterior wall of the feline left ventricle. Eur Heart J 1992;13:981-9.
    • (1992) Eur Heart J , vol.13 , pp. 981-989
    • Hexeberg, E.1    Birkeland, S.2    Grong, K.3    Matre, K.4    Lekven, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.