메뉴 건너뛰기




Volumn 43, Issue 2, 1998, Pages 212-216

(R)salsolinol N-methyltransferase activity increases in Parkinsonian lymphocytes

Author keywords

[No Author keywords available]

Indexed keywords

ISOQUINOLINE DERIVATIVE; METHYLTRANSFERASE; N METHYLSALSOLINOL; UNCLASSIFIED DRUG;

EID: 0031888815     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.410430211     Document Type: Article
Times cited : (63)

References (18)
  • 1
    • 0022408175 scopus 로고
    • Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine
    • Barbeua A, Roy M, Paris S, et al. Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine. Lancet 1985;2:1213-1215
    • (1985) Lancet , vol.2 , pp. 1213-1215
    • Barbeua, A.1    Roy, M.2    Paris, S.3
  • 2
    • 0024390719 scopus 로고
    • Mitochondrial complex I deficiency in Parkinson's disease
    • Schapira AHV, Cooper JM, Dexter D, et al. Mitochondrial complex I deficiency in Parkinson's disease. Lancet 1989;1: 1269
    • (1989) Lancet , vol.1 , pp. 1269
    • Schapira, A.H.V.1    Cooper, J.M.2    Dexter, D.3
  • 3
    • 0027464780 scopus 로고
    • Association of a monoamine oxidase B allele with Parkinson's disease
    • Kurth JH, Kurth MC, Poduslo SE, Schwankhaus JD. Association of a monoamine oxidase B allele with Parkinson's disease. Ann Neurol 1993;33:368-372
    • (1993) Ann Neurol , vol.33 , pp. 368-372
    • Kurth, J.H.1    Kurth, M.C.2    Poduslo, S.E.3    Schwankhaus, J.D.4
  • 5
    • 0029891783 scopus 로고    scopus 로고
    • A dopaminergic neurotoxin, (R)-N-methylsalsolinol, increases in parkinsonian cerebrospinal fluid
    • Maruyama W, Abe T, Tohgi H, et al. A dopaminergic neurotoxin, (R)-N-methylsalsolinol, increases in parkinsonian cerebrospinal fluid. Ann Neurol 1996;40:119-122
    • (1996) Ann Neurol , vol.40 , pp. 119-122
    • Maruyama, W.1    Abe, T.2    Tohgi, H.3
  • 6
    • 0030060483 scopus 로고    scopus 로고
    • Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: Biochemical, pathological and behavioral studies
    • Naoi M, Maruyama W, Dostert P, et al. Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies. Brain Res 1996;709:285-295
    • (1996) Brain Res , vol.709 , pp. 285-295
    • Naoi, M.1    Maruyama, W.2    Dostert, P.3
  • 7
    • 0030957199 scopus 로고    scopus 로고
    • An endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol, induces DNA damage in human dopaminergic neuroblastoma SH-SY5Y cells
    • Maruyama W, Naoi M, Kasamatsu T, et al. An endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol, induces DNA damage in human dopaminergic neuroblastoma SH-SY5Y cells. J Neurochem 1997;69:322-329
    • (1997) J Neurochem , vol.69 , pp. 322-329
    • Maruyama, W.1    Naoi, M.2    Kasamatsu, T.3
  • 8
    • 0031043805 scopus 로고    scopus 로고
    • A dopaminergic neurotoxin, 1(R), 2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl(R)salsolinol, and its oxidation product, 1,2(N)-dimethyl-6,7-dihydroxyisoquinolinium ion, accumulate in the nigro-striatal system of the human brain
    • Maruyama W, Sobe G, Matsubara K, et al. A dopaminergic neurotoxin, 1(R), 2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl(R)salsolinol, and its oxidation product, 1,2(N)-dimethyl-6,7-dihydroxyisoquinolinium ion, accumulate in the nigro-striatal system of the human brain. Neurosci Lett 1997;223:61-64
    • (1997) Neurosci Lett , vol.223 , pp. 61-64
    • Maruyama, W.1    Sobe, G.2    Matsubara, K.3
  • 9
    • 0030593511 scopus 로고    scopus 로고
    • A novel enzyme enantio- Selectively synthesizes (R)salsolinol, a precursor of a dopaminergic neurotoxin, N-methyl(R)salsolinol
    • Naoi M, Maruyama W, Dostert P, et al. A novel enzyme enantio-selectively synthesizes (R)salsolinol, a precursor of a dopaminergic neurotoxin, N-methyl(R)salsolinol. Neurosci Lett 1996;212:183-186
    • (1996) Neurosci Lett , vol.212 , pp. 183-186
    • Naoi, M.1    Maruyama, W.2    Dostert, P.3
  • 10
    • 0026753805 scopus 로고
    • N-Methylation of dopamine-derived 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, (R)-salsolinol, in rat brains: In vivo microdialysis study
    • Maruyama W, Nakahara D, Ota M, et al. N-Methylation of dopamine-derived 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, (R)-salsolinol, in rat brains: in vivo microdialysis study. J Neurochem 1992;59:395-400
    • (1992) J Neurochem , vol.59 , pp. 395-400
    • Maruyama, W.1    Nakahara, D.2    Ota, M.3
  • 11
    • 0029124292 scopus 로고
    • Enzymatic oxidation of the dopaminergic neurotoxin, 1(R), 2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, into 1,2(N)-dimethyl-6,7-dihydroxyisoquinolinium ion
    • Naoi M, Maruyama W, Zhang J-H, et al. Enzymatic oxidation of the dopaminergic neurotoxin, 1(R), 2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, into 1,2(N)-dimethyl-6,7-dihydroxyisoquinolinium ion. Life Sci 1995;57:1061-1066
    • (1995) Life Sci , vol.57 , pp. 1061-1066
    • Naoi, M.1    Maruyama, W.2    Zhang, J.-H.3
  • 12
    • 0030832958 scopus 로고    scopus 로고
    • +-like neurotoxin, 1,2-dimethyl- 6,7-dihydroxyisoquinolinium ion, in the substantia nigra of human brain
    • +-like neurotoxin, 1,2-dimethyl-6,7-dihydroxyisoquinolinium ion, in the substantia nigra of human brain. Neurosci Lett 1997;235:81-84
    • (1997) Neurosci Lett , vol.235 , pp. 81-84
    • Naoi, M.1    Maruyama, W.2    Matsubara, K.3    Hashizume, Y.4
  • 13
    • 0022490928 scopus 로고
    • Role of N-methyltransferases in the neurotoxicity associated with the metabolites of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and other 4-substituted pyridines present in the environment
    • Ansher S, Cadet J, Jakoby WB, Baker JK. Role of N-methyltransferases in the neurotoxicity associated with the metabolites of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and other 4-substituted pyridines present in the environment. Biochem Pharmacol 1986;35:3359-3363
    • (1986) Biochem Pharmacol , vol.35 , pp. 3359-3363
    • Ansher, S.1    Cadet, J.2    Jakoby, W.B.3    Baker, J.K.4
  • 14
    • 0024359987 scopus 로고
    • An N-methyltransferase in human brain catalyzes N-methylation of 1,2,3,4-tetrahydroisoquinoline into N-methyl-1,2,3,4-tetrahydroisoquinoline, a precursor of a dopaminergic neurotoxin, N-methylisoquinolinium ion
    • Naoi M, Matsuura S, Takahashi T, Nagatsu T. An N-methyltransferase in human brain catalyzes N-methylation of 1,2,3,4-tetrahydroisoquinoline into N-methyl-1,2,3,4-tetrahydroisoquinoline, a precursor of a dopaminergic neurotoxin, N-methylisoquinolinium ion. Biochem Biophys Res Commun 1989;161:1213-1219
    • (1989) Biochem Biophys Res Commun , vol.161 , pp. 1213-1219
    • Naoi, M.1    Matsuura, S.2    Takahashi, T.3    Nagatsu, T.4
  • 15
    • 0026777955 scopus 로고
    • Novel S-adenosylmethionine-dependent indole N-methylation of β-carbolines in brain particulate fractions
    • Matsubara K, Neafsey EJ, Collins MA. Novel S-adenosylmethionine-dependent indole N-methylation of β-carbolines in brain particulate fractions. J Neurochem 1992; 59:511-518
    • (1992) J Neurochem , vol.59 , pp. 511-518
    • Matsubara, K.1    Neafsey, E.J.2    Collins, M.A.3
  • 16
    • 0025822293 scopus 로고
    • N-Methylation of pyridines in Parkinson's disease
    • Green S, Buttrum S, Molloy H, et al. N-Methylation of pyridines in Parkinson's disease. Lancet 1991;338:120-121
    • (1991) Lancet , vol.338 , pp. 120-121
    • Green, S.1    Buttrum, S.2    Molloy, H.3
  • 17
    • 10544234193 scopus 로고    scopus 로고
    • Mapping of a gene for Parkinson's disease to chromosome 4q21-q23
    • Polymeropoulos MH, Higgins JJ, Golbe LI, et al. Mapping of a gene for Parkinson's disease to chromosome 4q21-q23. Science 1996;274:1197-1199
    • (1996) Science , vol.274 , pp. 1197-1199
    • Polymeropoulos, M.H.1    Higgins, J.J.2    Golbe, L.I.3
  • 18
    • 16944362288 scopus 로고    scopus 로고
    • Localization of a gene for autosomal recessive form of juvenile parkinsonism (AR-JP) to chromosome 6q25.2-27
    • Matsumine H, Saito M, Shimoda-Matsubayashi S, et al. Localization of a gene for autosomal recessive form of juvenile parkinsonism (AR-JP) to chromosome 6q25.2-27. Am J Hum Genet 1997;60:588-596
    • (1997) Am J Hum Genet , vol.60 , pp. 588-596
    • Matsumine, H.1    Saito, M.2    Shimoda-Matsubayashi, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.