A neutral N-methyltransferase activity in the striatum determines the level of an endogenous MPP+-like neurotoxin, 1,2-dimethyl-6,7- dihydroxyisoquinolinium ion, in the substantia nigra of human brains

Neuroscience Letters

Volumn 235, Issue 1-2, 1997, Pages 81-84

  Naoi, Makoto ^a   Maruyama, Wakako ^b   Matsubara, Kazuo ^c   Hashizume, Yoshio ^d  

^a NAGOYA INSTITUTE OF TECHNOLOGY   (Japan)

^b Dept Basic Gerontology Natl I   (Japan)

^c ASAHIKAWA MEDICAL COLLEGE   (Japan)

^d AICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

1,2 Dimethyl 6,7 dihydroxyisoquinolinium ion; Dopamine; N Methyl(R) salsolinol; N Methyltransferase; Neurotoxin; Nigro striatum; Parkinson's disease

Indexed keywords

CARNEGINE; METHYLTRANSFERASE; NEUROTOXIN;

ARTICLE; CATALYSIS; CORPUS STRIATUM; DOPAMINERGIC TRANSMISSION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME SYNTHESIS; HUMAN; HUMAN TISSUE; NEUROBLASTOMA; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; STEM CELL; SUBSTANTIA NIGRA;

CAUDATE NUCLEUS; CORPUS STRIATUM; FRONTAL LOBE; HUMANS; HYDROGEN-ION CONCENTRATION; ISOQUINOLINES; METHYLTRANSFERASES; PUTAMEN; SUBSTANTIA NIGRA; THALAMUS;

EID: 0030832958     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(97)00723-4     Document Type: Article

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