A novel enzyme enantio-selectively synthesizes (R)salsolinol, a precursor of a dopaminergic neurotoxin, N-methyl(R)salsolinol

Neuroscience Letters

Volumn 212, Issue 3, 1996, Pages 183-186

  Naoi, Makoto ^a   Maruyama, Wakako ^b   Dostert, Philippe ^c   Kohda, Kohfuku ^d   Kaiya, Toyo ^d  

^a NAGOYA INSTITUTE OF TECHNOLOGY   (Japan)

^b NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^c PFIZER INC   (United States)

^d NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

(R)Salsolinol; 1(R) Methyl 6,7 dihydroxy 1,2,3,4 tetrahydroisoquinoline; Dopamine; Human brain; N Methyl(R)salsolinol; Neurotoxin; Parkinson's disease

Indexed keywords

SALSOLINOL;

ARTICLE; BRAIN HOMOGENATE; CONTROLLED STUDY; DOPAMINE METABOLISM; ENANTIOMER; ENZYME PURIFICATION; HUMAN; HUMAN TISSUE; NEUROTOXICITY; NORMAL HUMAN; PARKINSON DISEASE; PRIORITY JOURNAL;

EID: 0030593511     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12807-X     Document Type: Article

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