Use of murine CXCR-4 as a second receptor by some T-cell-tropic human immunodeficiency viruses

Journal of Virology

Volumn 72, Issue 2, 1998, Pages 1652-1656

  Parolin, Cristina ^a,b   Borsetti, Alessandra ^a   Choe, Hyeryun ^a   Farzan, Michael ^a   Kolchinsky, Peter ^a   Heesen, Michael ^c   Ma, Qing ^d   Gerard, Craig ^e   Palu, Giorgio ^b   Dorf, Martin E ^c   Springer, Timothy ^d   Sodroski, Joseph ^a,e  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PADOVA   (Italy)

^c Department of Pathology ^*  (United States)

^d CENTER FOR BLOOD RESEARCH   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR; VIRUS RECEPTOR;

ANIMAL CELL; ARTICLE; DOG; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; THYMOCYTE; VIRUS INFECTIVITY;

EID: 0031883440     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.2.1652-1656.1998     Document Type: Article

References (64)

1. Alkhatib, G., C. Combadiere, C. C. Broder, Y. Feng, P. M. Murphy, and E. Berger. 1996. CC-CKR5: a RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272:1955-1958.
2. Allan, J., T. H. Lee, M. F. McLane, J. Sodroski, W. Haseltine, and M. Essex. 1983. Identification of the major envelope glycoprotein product of HTLV-III. Science 228:1091-1094.
3. Ashorn, P. A., E. A. Berger, and B. Moss. 1990. Human immunodeficiency virus envelope glycoprotein/CD4-mediated fusion of nonprimate cells with human cells. J. Virol. 64:2149-2156.
4. Atchison, R. E., J. Gosling, F. S. Monteclaro, C. Franci, L. Digilio, I. F. Charo, and M. A. Goldsmith. 1996. Multiple extracellular elements of CCR5 and HIV-1 entry: dissociation from response to chemokines. Science 274: 1924-1926.
5. Barre-Sinoussi, F., J. C. Chermann, F. Rey, M. T. Nugeyre, S. Chamaret, J. Gruest, C. Dauget, C. Axler-Bin, F. Vezinet-Brun, C. Rouzioux, W. Rozenbaum, and L. Montagnier. 1983. Isolation of a T-lymphocyte retrovirus from a patient at risk for acquired immunodeficiency syndrome (AIDS). Science 220:868-871.
6. Bieniasz, P. D., R. A. Fridell, I. Aramori, S. S. G. Ferguson, M. G. Caron, and B. R. Cullen. 1997. HIV-1 induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor. EMBO J. 16:2599-2609.
7. Bleul, C., M. Farzan, H. Choe, C. Parolin, I. Clark-Lewis, J. Sodroski, and T. Springer. 1996. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 382:829-833.
8. Cann, A. J., M. J. Churcher, M. Boyd, W. O'Brien, J.-Q. Zhao, J. Zack, and I. S. Y. Chen. 1992. The region of the envelope gene of human immunodeficiency virus type 1 responsible for determination of cell tropism. J. Virol. 66:305-309.
9. Carrillo, A., D. Trowbridge, P. Westervelt, and L. Ratner. 1993. Identification of HIV-1 determinants for T lymphoid cell line infection. Virology 197:817-824.
10. Cheng-Mayer, C., D. Seto, M. Tateno, and J. Levy. 1988. Biologic features of HIV-1 that correlate with virulence in the host. Science 240:80-82.
11. Cheng-Mayer, C., M. Quiroga, J. W. Tung, D. Dina, and J. A. Levy. 1990. Viral determinants of human immunodeficiency virus type 1 T-cell or macrophage tropism, cytopathogenicity, and CD4 antigen modulation. J. Virol. 64:4390-4398.
12. Chesebro, B., J. Nishio, S. Perryman, A. Cann, W. O'Brien, I. S. Y. Chen, and K. Wehrly. 1991. Identification of human immunodeficiency virus envelope gene sequences influencing viral entry into CD4-positive HeLa cells, T-leukemia cells, and macrophages. J. Virol. 65:5782-5789.
13. Chesebro, B., K. Wehrly, J. Nishio, and S. Perryman. 1992. Macrophage-tropic human immunodeficiency virus isolates from different patients exhibit unusual V3 envelope sequence homogeneity in comparison with T-cell-tropic isolates: definition of critical amino acids involved in cell tropism. J. Virol. 66:6547-6554.
14. Choe, H., M. Farzan, Y. Sun, N. Sullivan, B. Rollins, P. D. Ponath, L. Wu, C. R. MacKay, G. LaRosa, W. Newman, N. Gerard, C. Gerard, and J. Sodroski. 1996. The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 85:1-20.
15. Clapham, P. R., D. Blanc, and R. Weiss. 1991. Specific cell surface requirements for the infection of CD4-positive cells by human immunodeficiency virus types 1 and 2 and by simian immunodeficiency virus. Virology 181:703-715.
16. + T cells. Science 270:1811-1815.
17. Cocchi, F., A. L. DeVico, A. Garzino-Demo, A. Cara, R. C. Gallo, and P. Lusso. 1996. The V3 domain of the HIV-1 gp120 glycoprotein is critical for chemokine-mediated blockade of infection. Nat. Med. 2:1244-1247.
18. Dalgleish, A. G., P. C. L. Beverley, P. R. Clapham, D. H. Crawford, M. F. Greaves, and R. A. Weiss. 1984. The CD4 (T4) antigen is an essential component of the receptor tor the AIDS retrovirus. Nature 312:763-767.
19. Deng, H. K., S. Choe, W. Ellmeier, R. Liu, D. Unutmaz, M. Burkhart, P. di Marzio, S. Marmon, R. E. Sutton, C. M. Hill, C. Davis, S. C. Peiper, T. J. Schall, D. R. Littman, and N. R. Landau. 1946. Identification of a major co-receptor for primary isolates of HIV-1. Nature 381:661-666.
20. Desrosiers, R. C., A. Hansen-Moosa, K. Mori, D. P. Bouvier, N. W. King, M. D. Daniel, and D. J. Ringler. 1991. Macrophage-tropic variants of SIV are associated with specific AIDS-related lesions hut are not essential for the development of AIDS. Am. J. Pathol. 139:29-35.
21. Doranz, B., J. Rucker, Y. Yi, R. Smyth, M. Samson, S. Peiper, M. Parmentier, R. Collman, and R. Doms. 1996. A dual-tropic primary HIV-1 isolate that uses fusin and the β-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofaclors. Cell 85:1149-1158.
22. + cells is mediated by the chemokine receptor CC-CKR-5. Nature 381:667-673.
23. Farzan, M., H. Choe, K. Martin, Y. Sun, M. Sidelko, C. Mackay, N. Gerard, J. Sodroski, and C. Gerard. 1997. MIP-1β-mediated signaling and HIV-1 entry are independent functions of the chemokine receptor CCR5. J. Biol. Chem. 272:6854-6857.
24. Fauci, A., A. Macher, D. Longo, H. C. Lane, A. Rook, H. Masur, and E. Gelmann. 1984. Acquired immunodeficiency syndrome: epidemiologic, clinical, immunologic, and therapeutic considerations. Ann. Intern. Med. 100: 92-106.
25. Federsppiel, B., I. Melhado, A. Duncan, A. Delaney, K. Schappert, I. Clark-Lewis, and F. Jirik. 1993. Molecular cloning of the cDNA and chromosomal localization of the gene for a putative seven-transmembrane segment (7-TMS) receptor isolated from human spleen. Genomics 16:707-712.
26. Feng, Y., C. C. Broder, P. E. Kennedy, and E. A. Berger. 1996. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 272:872-877.
27. Fenyö, E. M., L. Morfeldt-Manson, F. Chiodi, B. Lind, A. von Gegerfelt, J. Albert, E. Olausson, and B. Åsjö. 1988. Distinct replicative and cytopathic characteristics of human immunodeficiency virus isolates. J. Virol. 62:4414-4419.
28. Gallo, R. C., S. Z. Salahuddin, M. Popovic, G. M. Shearer, M. Kaplan, B. F. Haynes, T. J. Palker, R. Redfield, J. Oleske, B. Safai, G. White, P. Foster, and P. D. Markham. 1984. Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS. Science 272:872-877.
29. Gartner, S., P. Markovits, D. Markovitz, M. Kaplan, R. Gallo, and M. Popovic. 1986. The role of mononuclear phagocytes in HTLV-III/LAV infection. Science 233:215-219.
30. Gendelman, H., J. Orenstein, M. Martin, C. Ferrva, R. Mitra, T. Phipps, L. Wahl, C. Lane, A. Fauci, and D. Burke. 1988. Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes. J. Exp. Med. 167:1428-1441.
31. Heesen, M., M. A. Berman, J. D. Benson, C. Gerard, and M. E. Dorf. 1996. Cloning of the mouse fusin gene, homologue to a human HIV-1 co-factor. J. Immunol. 157:5455-5460.
32. Heesen, M., M. A. Berman, U. E. Höpken, N. P. Gerard, and M. E. Dorf. 1997. Alternative splicing of mouse fusin/CXCR-4. SDF-1 is a ligand for both CXCR-4 isoforms. J. Immunol. 158:3561-3564.
33. Helseth, E., M. Kowalski, D. Gabuzda, U. Olshevsky, W. Haseltine, and J. Sodroski. 1990. Rapid complementation assays measuring replicative potential of HIV-1 envelope glycoprotein mutants. J. Virol. 64:2416-2420.
34. Hwang, S., T. Boyle, H. Lyerly, and B. Cullen. 1991. Identification of the V3 loop as the primary determinant of cell tropism in HIV-1. Science 253:71-74.
35. Klatzmann, D., E. Champagne, S. Chamaret, J. Gruest, D. Guetard, T. Hercend, J. C. Gluckman, and L. Montagnier. 1984. T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature 312:767-768.
36. Koenig, S., H. E. Gendelman, J. M. Orenstein, M. C. Dal Canto, G. H. Pezeshkpour, M. Yungbluth, F. Janotta, A. Aksamit, M. A. Martin, and A. S. Fauci. 1986. Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 233:1089-1093.
37. Kowalski, M., J. Potz, L. Basiripour, T. Dorfman, W. C. Goh, E. Terwilliger, A. Dayton, C. Rosen, W. Haseltine, and J. Sodroski. 1987. Functional regions of the human immunodeficiency virus envelope glycoproteins. Science 237: 1351-1355.
38. Lapham, C. K., J. Ouyang, B. Chandrasekhar, N. Y. Nguyen, D. Dimitrov, and H. Golding. 1996. Evidence for cell-surface association between fusin and CD4-gp120 complex in human cell lines. Science 274:602-605.
39. Lifson, J., M. Feinberg, G. Reyes, L. Rabin, B. Banapour, S. Chakrabarti, B. Moss, F. Wong-Staal, K. Steimer, and E. Engelman. 1986. Induction of CD4-dependent cell fusion by the HTLV-III/LAV envelope glycoprotein. Science 323:725-728.
40. Loetscher, M., T. Geiser, T. O'Reilly, R. Zwahlen, M. Baggiolini, and B. Moser. 1994. Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes. J. Biol. Chem. 269:232-237.
41. Maddon, P. J., A. G. Dalgleish, J. S. McDougal, P. R. Clapham, R. A. Weiss, and R. Axel. 1986. The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell 47:333-348.
42. + T cells by a complex of the 100K viral protein and the T4 molecule. Science 231:382-385.
43. McKnight, A., P. R. Clapham, and R. A. Weiss. 1994. HIV-2 and SIV infection of nonprimate cell lines expressing human CD4: restrictions to replication at distinct stages. Virology 201:8-18.
44. Nagasawa, T., T. Nakajima, K. Tachibana, H. Iizasa, C. Bleul, O. Yoshie, K. Matsushima, N. Yoshida, T. Springer, and T. Kishimoto. 1996. Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin. Proc. Natl. Acad. Sci. USA 93:14726-14729.
45. Oberlin, E., A. Amara, F. Bachelerie, C. Bessia, J.-L. Virelizier, F. Arenzana-Seisdedos, O. Schwartz, J.-M. Heard, I. Clark-Lewis, D. F. Legler, M. Loetscher, M. Baggiolini, and B. Moser. 1996. The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature 382:833-835.
46. O'Brien, W. A., Y. Koyanagi, A. Namazie, J.-Q. Zhao, A. Diagne, K. Idler, J. A. Zack, and I. S. Y. Chen. 1990. HIV-1 tropism for mononuclear phagocytes can be determined by regions of gp120 outside the CD4-binding domain. Nature 348:69-73.
47. Paxton, W. A., S. Martin, D. Tse, T. O'Brien, J. Skurnick, N. Van Devanter, N. Padian, J. Braun, D. Kotler, S. Wolinsky, and R. Koup. 1996. Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposures. Nat. Med. 2:412-417.
48. + cells expressing the rat homolog of CXCR-4 (fusin). J. Virol. 71:3259-3262.
49. Pope, M., M. Betjes, N. Romani, H. Hirmand, P. Cameron, L. Hoffman, S. Gezelter, G. Schuler, and R. Steinman. 1994. Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1. Cell 78:389-398.
50. Raport, C., J. Gosling, V. Schweickart, P. Gray, and I. Charo. 1996. Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIF-1β, and MIP-1α. J. Biol. Chem. 271: 17161-17166.
51. Ringler, D. J., M. S. Wyand, D. G. Walsh, J. J. MacKey, P. K. Sehgal, M. D. Daniel, R. C. Desrosiers, and N. W. King. 1989. The productive infection of alveolar macrophages by simian immunodeficiency virus. J. Med. Primatol. 18:217-226.
52. Robey, W. G., B. Safai, S. Oroszlan, L. Arthur, M. Gonda, R. Gallo, and P. J. Fischinger. 1985. Characterization of envelope and core structural gene products of HTLV-III with sera from AIDS patients. Science 228:593-595.
53. Rucker, J., M. Samson, B. J. Doranz, F. Libert, J. F. Berson, Y. Yi, R. J. Smyth, R. G. Collman, C. C. Broder, G. Vassart, R. W. Doms, and M. Parmentier. 1996. Regions in β-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity. Cell 87:437-446.
54. Samson, M., O. Labbe, C. Mollereau, G. Vassart, and M. Parmentier. 1996. Molecular cloning and functional expression of a new human CC-chemokine receptor gene. Biochemistry 35:3362-3367.
55. Schuitemaker, H., M. Koot, N. A. Kootstra, M. W. Dercksen, R. E. Y. de Goede, R. P. van Steenwijk, J. M. A. Lange, J. K. M. Eeftink-Schattenkerk, F. Miedema, and M. Tersmette. 1992. Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus populations. J. Virol. 66:1354-1360.
56. Shioda, T., J. A. Levy, and C. Cheng-Mayer. 1991. Macrophage and T cell-line tropisms of HIV-1 are determined by specific regions of the envelope gp120 gene. Nature 349:167-169.
57. Sodroski, J., W. C. Goh, C. A. Rosen, K. Campbell, and W. Haseltine. 1986. Role of the HTLV-III envelope in syncytium formation and cytopathicity. Nature 321:412-417.
58. Stein, B., S. Gouda, J. Lifson, R. Penhallow, K. Bensch, and E. Engelman. 1987. pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane. Cell 49:659-668.
59. Trkola, A., T. Dragic, J. Arthos, J. Binley, W. Olson, G. Allaway, C. Cheng-Mayer, J. Robinson, P. Maddon, and J. Moore. 1996. CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5. Nature 384:184-187.
60. Weissman, D., Y. Li, J. Ananworanich, L.-J. Zhou, J. Adelsberger, T. Tedder, M. Baseler, and A. Fauci. 1995. Three populations of cells with dendritic morphology exist in peripheral blood, only one of which is infectible with human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 92:826-830.
61. Westervelt, P., H. E. Gendelman, and L. Ratner. 1991. Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes. Proc. Natl. Acad. Sci. USA 88:3097-3101.
62. Westervelt, P., D. Trowbridge, L. Epstein, B. Blumberg, Y. Li, B. Hahn, G. Shaw, R. Price, and L. Ratner. 1992. Macrophage tropism determinants of human immunodeficiency virus type 1 in vivo. J. Virol. 66:2577-2582.
63. Wieder, K. J., P. Chatis, J. Boltax, I. Wieder, G. Nuovo, and T. B. Strom. 1996. Human immunodeficiency virus type 1 entry into murine cell lines and lymphocytes from transgenic mice expressing a glycoprotein 120-binding mutant mouse CD4. AIDS Res. Hum. Retroviruscs 12:867-876.
64. Wu, L., N. Gerard, R. Wyatt, H. Choe, C. Parolin, N. Ruffing, A. Borsetti, A. Cardoso, E. Desjardins, W. Newman, C. Gerard, and J. Sodroski. 1996. CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR5. Nature 384:179-183.