Expression and localization of GDNF in developing and adult adrenal chromaffin cells

Cell and Tissue Research

Volumn 286, Issue 2, 1996, Pages 263-268

  Krieglstein, Kerstin ^a   Deimling, Frauke ^a   Suter Crazzolara, Clemens ^a   Unsicker, Klaus ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Bovine; Chromaffin cells; Immunocytochemistry; Neurotrophic factor; Rat (Hannover Wistar); RT PCR; Western blotting

Indexed keywords

MESSENGER RNA; NEURITE PROMOTING FACTOR;

ADRENAL MEDULLA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHROMAFFIN CELL; FEMALE; IMMUNOREACTIVITY; MALE; NONHUMAN; PREGANGLIONIC NERVE CELL; PRIORITY JOURNAL; SPINAL CORD; STEM CELL;

ADRENAL MEDULLA; AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ANTIBODY SPECIFICITY; BLOTTING, WESTERN; CATTLE; CHROMAFFIN CELLS; EPINEPHRINE; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; IMMUNOHISTOCHEMISTRY; MALE; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; NOREPINEPHRINE; POLYMERASE CHAIN REACTION; RATS; RATS, WISTAR; RNA, MESSENGER;

ANIMALIA; BOVINAE;

EID: 0029831731     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410050696     Document Type: Article

References (29)

1. Arenas E, Trupp M, Åkerud P, Ibáñez CF (1995) GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo. Neuron 15:1465-1473
2. Beck KD, Valverde J, Alexi T, Poulsen K, Moffat B, Vandlen RA, Rosenthal A, Hefti F (1995) Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature 373:339-341
3. Blottner D, Unsicker K (1990) Maintenance of intermediolateral spinal cord neurons by fibroblast growth factor administered to the medullectomized rat adrenal gland: dependence on intact adrenal innervation and cellular organization of implants. Eur J Neurosci 2:378-382
4. Blottner D, Brüggemann W, Unsicker K (1989) Ciliary neurotrophic factor supports target-deprived preganglionic sympathetic spinal cord neurons. Neurosci Lett 105:316-320
5. Blottner D, Wolf N, Lachmund A, Flanders KC, Unsicker K (1996) TGF-β rescues target-derived preganglionic sympathetic neurons in the spinal cord. Eur J Neurosci 8:202-210
6. Buj-Bello A, Buchman VL, Horton A, Rosenthal A, Davies AM (1995) GDNF is an age-specific survival factor for sensory and autonomic neurons. Neuron 15:821-828
7. Choi-Lundberg DL, Bohn MC (1995) Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat. Dev Brain Res 85:80-88
8. Ebendal T, Tomac A, Hoffer BJ, Olson L (1995) Glial cell line-derived neurotrophic factor stimulates fiber formation and survival in cultured neurons from peripheral autonomic ganglia. J Neurosci Res 40:276-284
9. Gash DM, Zhang Z, Ovadia A, Cass WA, Yi A, Simmerman L, Russell D, Martin D, Lapchak PA, Collins F, Hoffer BJ, Gerhardt GA (1996) Functional recovery in parkinsonian monkeys treated with GDNF. Nature 380:252-255
10. Henderson CE, Phillips HS, Pollock RA, Davies AM, Lemeulle C. Armanini M, Simpson LC, Moffet B, Vandlen RA, Koliatsos VE, Rosenthal A (1994) GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Science 266:1062-1068
11. Hoffer BJ, Hoffman A, Bowenkamp K, Huettl P, Hudson J, Martin D, Lin L-FH, Gerhardt GA (1994) Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo. Neurosci Lett 182:107-111
12. Humpel C, Hoffer B, Strömberg I, Bektesh S, Collins F, Olson L (1994) Neurons of the hippocampal formation express glial cell line-derived neurotrophic factor messenger rna in response to kainate-induced excitation. Neuroscience 59:791-795
13. Kingsley DM (1994) The TGP-beta superfamily - new members, new receptors, and new genetic tests of function in different organisms. Gene Dev 8:133-146
14. Krieglstein K, Rufer M, Suter-Crazzolara C, Unsicker K (1995) Neural functions of the transforming growth factors b. Int J Dev Neurosci 13:301-315
15. Lachmund A, Gehrke D, Krieglstein K, Unsicker K (1994) Trophic factors from chromaffin granules promote survival of peripheral and central nervous system neurons. Neuroscience 62:361-370
16. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
17. Lapchak PA, Jiao SS, Miller PJ, Williams LR, Cummins V, Inouye G, Matheson C, Yan Q (1996) Pharmacological characterization of glial cell line-derived neurotrophic factor (GDNF): implications for GDNF as a therapeutic molecule to treat neurodegenerative diseases. Cell Tissue Res 286: 179-189
18. Lin L-FH,Doherty DH, Lile JD, Bektesh S, Collins F (1993) GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260:1130-1132
19. Lin L-FH, Zhang TJ, Collins F, Armes LG (1994) Purification and initial characterization of rat B49 glial cell line-derived neurotrophic factor. J Neurochem 63:758-768
20. Oppenheim RW, Houenou LJ, Johnson JE, Lin L-FH, Li L, Lo AC, Newsome AL, Prevette DM, Wang S (1995) Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF. Nature 373:344-346
21. Schaar DG, Sieber BA, Dreyfus CF, Black IB (1993) Regional and cell-specific expression of GDNF in rat brain. Exp Neurol 124:368-371
22. Strömberg I, Bjorklund L, Johansson M, Tomac A, Collins F, Olson L, Hoffer B, Humpel C (1993) Glial cell line-derived neurotrophic factor is expressed in the developing but not adult striatum and stimulates developing dopamine neurons in vivo. Exp Neurol 124:401-412
23. Suter-Crazzolara C, Unsicker K (1994) GDNF is expressed in two forms in many tissues outside the CNS. Neuroreport 5:2486-2488
24. Suter-Crazzolara C, Unsicker K (1996) GDNF mRNA levels are induced by FGF-2 in rat C6 glioblastoma cells. Mol Brain Res (in press)
25. Tomac A, Widenfalk J, Lin LFH, Kohno T, Ebendal T, Hoffer BJ, Olson L (1995) Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult. Proc Natl Acad Sci USA 92:8274-8278
26. Trupp M, Rydén M, Jörnvall H, Funakoshi H, Timmusk T, Arenas E, Ibáñez CF (1995) Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J Cell Biol 130:137-148
27. Unsicker K (1996) GDNF: a cytokine at the interface of TGF-βs and neurotrophins. Cell Tissue Res 286:175-178
28. Wolf N, Bieger S, Unsicker K, Krieglstein K (1994) Does TGF-β regulate chromaffin cell proliferation? Soc Neurosci Abstr 20:1689
29. Yan Q, Matheson C, Lopez OT (1995) In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature 373:341-344