p300 Family members associate with the carboxyl terminus of simian virus 40 large tumor antigen

Journal of Virology

Volumn 71, Issue 1, 1997, Pages 129-137

  Lill, Nancy L ^a   Tevethia, Mary Judith ^b   Eckner, Richard ^a,c   Livingston, David M ^a   Modjtahedi, Nazanine ^a,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; ONCOPROTEIN; PHOSPHOPROTEIN; PROTEIN P53; VIRUS LARGE T ANTIGEN;

ANTIGEN BINDING; ARTICLE; CARBOXY TERMINAL SEQUENCE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; SIMIAN VIRUS 40;

EID: 0031060151     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.1.129-137.1997     Document Type: Article

References (93)

1. Abraham, S. E., S. Lobo, P. Yaciuk, H. G. Wang, and E. Moran. 1993. p300, and p300-associated proteins, are components of TATA-binding protein (TBP) complexes. Oncogene 8:1639-1647.
2. Arany, Z., D. Newsome, E. Oldread, D. M. Livingston, and R. Eckner. 1995. A family of transcriptional adaptor proteins targeted by the E1A oncoprotein. Nature (London) 374:81-84.
3. Avantaggiati, M. L., M. Carbone, A. Graessmann, Y. Nakatani, B. Howard, and A. S. Levine. 1996. The SV40 large T antigen and adenovirus E1a oncoproteins interact with distinct isoforms of the transcriptional co-activator, p300. EMBO J. 15:2236-2248.
4. Bagchi, S., P. Raychaudhuri, and J. R. Nevins. 1990. Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor; a novel mechanism for E1A trans-activation. Cell 62:659-669.
5. Bandara, L. R., and N. B. LaThangue. 1991. Adenovirus E1A prevents the retinoblastoma gene product from complexing with a cellular transcription factor. Nature (London) 351:494-497.
6. Barbeau, D., R. Charbonneau, S. G. Whalen, S. T. Bayley, and P. E. Branton. 1994. Functional interactions within adenovirus E1A protein complexes. Oncogene 9:359-373.
7. Bayley, S. T., and J. S. Mymryk. 1994. Adenovirus E1A proteins and transformation. Int. J. Oncol. 5:425-144.
8. Boulukos, K. E., and E. B. Ziff. 1993. Adenovirus 5 E1A proteins disrupt the neuronal phenotype and growth factor responsiveness of PC12 cells by a conserved region 1-dependent mechanism. Oncogene 8:237-248.
9. Braithwaite, A. W., G. E. Blair, C. C. Nelson, J. McGovern, and A. J. D. Bellett. 1991. Adenovirus E1b-58kD antigen binds to p53 during infection of rodent cells: evidence for an N-terminal binding site on p53. Oncogene 6:781-787.
10. Caruso, M., F. Martelli, A. Giordano, and A. Felsani. 1993. Regulation of Myo D gene transcription and protein function by the transforming domains of the adenovirus E1A oncoprotein. Oncogene 8:267-278.
11. Cavender, J. F., A. Conn, M. Epler, H. Lacko, and M. J. Tevethia. 1995. Simian virus 40 large T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblasts. J. Virol. 69:923-934.
12. Chen, S., and E. Paucha. 1990. Identification of a region of simian virus 40 large T antigen required for cell transformation. J. Virol. 64:3350-3357.
13. Clark, R., K. Peden, J. M. Pipas, D. Nathans, and R. Tjian. 1983. Biochemical activities of T-antigen proteins encoded by simian virus 40 A gene mutants. Mol. Cell. Biol. 3:220-228.
14. DeCaprio, J. A., J. W. Ludlow, J. Figge, J.-Y. Shew, C.-M. Huang, W.-H. Lee, E. Marsilio, E. Paucha, and D. M. Livingston. 1988. SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 54:275-283.
15. Deppert, W., M. Haug, and T. Steinmayer. 1987. Modulation of p53 protein expression during cellular transformation with simian virus 40. Mol. Cell. Biol. 7:4453-4463.
16. Dyson, N., R. Bernards, S. H. Friend, L. R. Gooding, J. A. Hassell, E. O. Major, J. M. Pipas, T. Van Dyke, and E. Harlow. 1990. Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein. J. Virol. 64:1353-1356.
17. Dyson, N., K. Buchkovich, P. Whyte, and E. Harlow. 1989. The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC. Cell 58:249-255.
18. Dyson, N., P. Guida, C. McCall, and E. Harlow. 1992. Adenovirus E1A makes two distinct contacts with the retinoblastoma protein. J. Virol. 66:4606-4611.
19. Dyson, N., P. Guida, K. Munger, and E. Harlow. 1992. Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins. J. Virol. 66:6893-6902.
20. Dyson, N., P. M. Howley, K. Munger, and E. Harlow. 1989. The human papillomavirus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 243:934-937.
21. Eckner, R., M. E. Ewen, D. Newsome, M. Gerdes, J. A. DeCaprio, J. B. Lawrence, and D. M. Livingston. 1994. Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev. 8:869-884.
22. Eckner, R., J. W. Ludlow, N. L. Lill, E. Oldread, Z. Arany, N. Modjtahedi, J. A. DeCaprio, D. M. Livingston, and J. A. Morgan. 1996. Association of p300 and CBP with simian virus 40 large T antigen. Mol. Cell. Biol. 16:3454-3464.
23. Eckner, R. E., N. L. Lill, and D. M. Livingston. Unpublished data.
24. Eckner, R., T.-P. Yao, E. Oldread. and D. M. Livingston. 1996. Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. Genes Dev. 10:2478-2490.
25. Egan, C., T. N. Jelsma, J. A. Howe, S. T. Bayley, B. Ferguson, and P. E. Branton. 1988. Mapping of cellular protein-binding sites on the products of early-region 1A of human adenovirus type 5. Mol. Cell. Biol. 8:3955-3959.
26. Rb and a second cellular protein, p120. Cell 58:257-267.
27. Ewen, M. E., Y. Xing. J. B. Lawrence, and D. M. Livingston. 1991. Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein. Cell 66:1155-1164.
28. Farmer, G., J. Bargonetti, H. Zhu, P. Friedman, R. Prywes, and C. Prives. 1992. Wild-type p53 activates transcription in vitro. Nature (London) 358:83-86.
29. Fogh, J., and G. Trempe. 1975. New human tumor cell lines, p. 115-159. In J. Fogh (ed.), Human tumor cells in vitro. Plenum Press. New York, N.Y.
30. Giordano, A., C. McCall, P. Whyte, and B. R. Franza, Jr. 1991. Human cyclin A and the retinoblastoma protein interact with similar but distinguishable sequences in the adenovirus E1A gene product. Oncogene 6:481-485.
31. Graham, F. L., J. Smiley, W. C. Russell, and R. Nairn. 1977. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J. Gen. Virol. 36:59-74.
32. Grand, R. J. A., M. L. Grant, and P. H. Gallimore. 1994. Enhanced expression of p53 in human cells infected with mutant adenoviruses. Virology 203:229-240.
33. Gruda, M. C., J. M. Zabolotny, J. H. Xiao, I. Davidson, and J. C. Alwine. 1993. Transcription activation by simian virus 40 large T antigen: interactions with multiple components of the transcription complex. Mol. Cell. Biol. 13:961-969.
34. Hannon, G. J., D. Demetrick, and D. Beach. 1993. Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. Genes Dev. 7:2378-2391.
35. Harlow, E., L. V. Crawford, D. C. Pim, and N. M. Williamson. 1981. Monoclonal antibodies specific for simian virus 40 tumor antigens. J. Virol. 39:861-869.
36. Harlow, E., B. R. Franza, and C. Schley. 1985. Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products. J. Virol. 55:533-546.
37. Harlow, E., P. Whyte, B. R. Franza, Jr., and C. Schley. 1986. Association of adenovirus early-region 1A proteins with cellular polypeptides. Mol. Cell. Biol. 6:1579-1589.
38. Heasley, L. E., S. Benedict, J. Gleary, and G. L. Johnson. 1991. Requirement of the adenovirus E1A transformation domain 1 for inhibition of PC12 cell neuronal differentiation. Cell Regul. 2:479-489.
39. Howe, J. A.,and S. T. Bayley. 1992. Effects of Ad5 E1A mutant viruses on the cell cycle in relation to the binding of cellular proteins. Virology 186:15-24.
40. Howe, J. A-, J. S. Mymryk, C. Egan, P. E. Branton, and S. T. Bayley. 1990. Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis. Proc. Natl. Acad. Sci. USA 87:5883-5887.
41. Jelsma, T. N., J. A. Howe, J. S. Mymryk, C. M. Evelegh, N. F. A. Cunniff, and S. T. Bayley. 1989. Sequences in E1A proteins of human adenovirus 5 required for cell transformation, repression of a transcriptional enhancer, and induction of proliferating cell nuclear antigen. Virology 171:120-130.
42. Jiang, D., A. Srinivasan, G. Lozano, and P. D. Robbins. 1993. SV40 T antigen abrogates p53-mediated transcriptional activity. Oncogene 8:2805-2812.
43. Johnston, S. D., X.-M. Yu, and J. E. Mertz. 1996. The major transcriptional transactivation domain of simian virus 40 large T antigen associates nonconcurrently with multiple components of the transcriptional preinitiation complex. J. Virol. 70:1191-1202.
44. Kalderon, D., and A. E. Smith. 1984. In vitro mutagenesis of a putative DNA binding domain of SV40 large-T. Virology 139:109-137.
45. Kalman, D., K. Whittaker, J. M. Bishop, and P. H. O'Lague. 1993. Domains of E1A that bind p105Rb, p130, and p300 are required to block nerve growth factor-induced neurite growth in PC12 cells. Mol. Cell. Biol. 4:353-361.
46. Kierstead, T. D., and M. J. Tevethia. 1993. Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutations. J. Virol. 67:1817-1829.
47. Kirschenbaum, L. A., and M. D. Schneider. 1995. Adenovirus E1A represses cardiac gene transcription and reactivates DNA synthesis in ventricular myocytes via alternative pocket protein- and p300-binding domains. J. Biol. Chem. 270:7791-7794.
48. Kitabayashi, I., R. Eckner, Z. Arany, R. Chiu, G. Gachelin, D. M. Livingston, and K. K. Yokoyama. 1995. Phosphorylation of the adenovirus E1A-associated 300 kDa protein in response to retinoic acid and E1A during the differentiation of F9 cells. EMBO J. 14:3496-3509.
49. Kress, M., E. May, R. Cassingena, and P. May. 1979. Simian virus 40-transformed cells express new species of proteins precipitable by anti-simian virus 40 tumor serum, J. Virol. 31:472-483.
50. Lane, D. P., and L. V. Crawford. 1979. T antigen is bound to a host protein in SV40-transformed cells. Nature (London) 278:261-263.
51. Lee, J.-S., K. M. Galvin, R. H. See, R. Eckner, D. Livingston, E. Moran, and Y. Shi. 1995. Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300. Genes Dev. 9:1188-1198.
52. Linzer, D. I. H., and A. J. Levine. 1979. Characterization of a 54K dalton cellular SV40 tumor antigen in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell 17:43-52.
53. Ludlow, J. W., J. A. DeCaprio, C.-M. Huang, W.-H. Lee, E. Paucha, and D. M. Livingston. 1989. SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family. Cell 56:57-65.
54. Lundblad, J. R., R. P. S. Kwok, M. E. Laurance, M. L. Harter, and R. H. Goodman. 1995. Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP. Nature (London) 374:85-88.
55. Mayol, X., X. Grana, A. Baldi, N. Sang, Q. Hu, and A. Giordano. 1993. Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain. Oncogene 8:2561-2566.
56. McAllister, R. M., M. B. Gardner, A. E. Greene, C. Bradt, W. M. Nichols, and B. H. Landing. 1971. Cultivation in vitro of cells derived from a human osteosarcoma. Cancer 27:397-402.
57. Mietz, J. A., T. Unger, J. M. Huibregtse, and P. M. Howley. 1992. The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. EMBO J. 11:5013-5020.
58. Missero, C., E. Calautti, R. Eckner, J. Chin, L. H. Tsai, D. M. Livingston, and G. P. Dotto. 1995. Involvement of the cell cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc. Natl. Acad. Sci. USA 92:5451-5455.
59. Mole, S. E., J. V. Gannon, M. J. Ford, and D. P. Lane. 1987. Structure and function of SV40 large T antigen. Proc. R. Soc. Lond. B 317:455-469.
60. Moran, B., and B. Zerler. 1988. Interactions between cell growth-regulating domains in the products of the adenovirus E1A oncogene. Mol. Cell. Biol. 8:1756-1764.
61. Moran, E. 1993. DNA tumor virus transforming proteins and the cell cycle. Curr. Opin. Genet. Dev. 3:63-70.
62. Mymryk, J. S., R. W. H. Lee, and S. T. Bayley. 1992. Ability of adenovirus 5E1A proteins to suppress differentiation of BC3H1 myoblasts correlates with their binding to a 300-kDa cellular protein. Mol. Biol. Cell. 3:1107-1115.
63. Oren, M., W. Maltzman, and A. J. Levine. 1981. Posttranslational regulation of the 54K cellular tumor antigen in normal and transformed cells. Mol. Cell. Biol. 1:101-110.
64. Ponten, J., and E. Saksela. 1967. Two established in vitro cell lines from human mesenchymal tumors. Int. J. Cancer 2:434-447.
65. Sarnow, P., Y. S. HO, J. Williams, and A. J. Levine. 1982. Adenovirus E1B-58 kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells. Cell 28:387-394.
66. Scheffner, M., B. A. Werness, J. M. Huibregtse, A. J. Levine, and P. M. Howley. 1990. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63:1129-1136.
67. Segawa, K., A. Minowa, K. Sugasawa, T. Takano, and F. Hanaoka. 1993. Abrogation of p53-mediated transactivation by SV40 large T antigen. Oncogene 8:543-548.
68. Slack, R. S., J. Craig, S. Costa, and M. W. McBurney. 1995. Adenovirus 5 E1A induced differentiation of P19 embryonal carcinoma cells requires binding to p300, Oncogene 10:19-25.
69. Smith, A. E., R. Smith, and E. Paucha. 1978. Extraction and fingerprint analysis of simian virus 40 large and small T-antigens. J. Virol. 28:140-153.
70. Stein, R. W., M. Corrigan, P. Yaciuk, J. Whalen, and E. Moran. 1990. Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activity, J. Virol. 64:4421-4427.
71. Subramanian, T., M. Kuppuswamy, R. J. Nasr, and G. Chinnadurai. 1988. An N-terminal region of adenovirus E1a essential for cell transformation and induction of an epithelial cell growth factor. Oncogene 2:105-112.
72. Svensson, C., M. Bondesson, E. Nyberg, S. Linder, N. Jones, and G. Akusjarvi. 1991. Independent transformation activity by adenovirus-5 E1A-conserved region 1 or 2 mutants. Virology 182:553-561.
73. Thompson, D. L., D. Kalderon, A. E. Smith, and M. J. Tevethia. 1990. Dissociation of Rb-binding and anchorage-independent growth from immortalization and tumorigenicity using SV40 mutants producing N-terminally truncated large T antigens. Virology 178:15-34.
74. Todaro, G. J., H. Green, and M. R. Swift. 1966. Susceptibility of human diploid fibroblast strains to transformation by SV40 virus. Science 153:1252-1254.
75. Topp, W. 1981. Normal rat cell lines deficient in nuclear thymidine kinase. Virology 113:408-111.
76. van den Heuvel, S. J. L., T. van Laar, W. M. Kast, C. J. M. Melief, A. Zantema, and A. J. van der Eb. 1990. Association between the cellular p53 and the adenovirus 5 E1B-55kd proteins reduces the oncogenicity of Ad-transformed cells. EMBO J. 9:2621-2629.
77. Wang, H.-G. H., E. Moran, and P. Yaciuk. 1995. E1A promotes association between p300 and pRB in multimeric complexes required for normal biological activity. J. Virol. 69:7917-7924.
78. Wang, H.-G. H., Y. Rikitake, M. C. Carter, P. Yaciuk, S. E. Abraham, B. Zerler, and E. Moran. 1993. Identification of specific adenovirus E1A N-terminal residues critical in the binding of cellular proteins and to the control of cell growth. J. Virol. 67:476-488.
79. Weintraub, S. J., C. A. Prater, and D. C. Dean. 1992. Retinoblastoma protein switches the E2F site from positive to negative element. Nature (London) 358:259-261.
80. Whyte, P., H. E. Ruley, and E. Harlow. 1988. Two regions of adenovirus early region 1A proteins are required for transformation. J. Virol. 62:257-265.
81. Whyte, P., N. M. Williamson, and E. Harlow. 1989. Cellular targets for transformation by the adenovirus E1A proteins. Cell 56:67-75.
82. Wolf, D. A., H. Hermeking, T. Albert, T. Herzinger, P. Kind, and D. Eick. 1995. A complex between E2F and the pRb-related protein p130 is specifically targeted by the simian virus 40 large T antigen during cell transformation. Oncogene 10:2067-2078.
83. Wright, W. E., M. Binder, and W. Funk. 1991. Cyclic amplification and selection of targets (CASTing) for the myogenin consensus binding site. Mol. Cell. Biol. 11:4104-4110.
84. Yaciuk, P., M. C. Carter, J. M. Pipas, and E. Moran. 1991. Simian virus 40 large-T antigen expresses a biological activity complementary to the p300-associated transforming function of the adenovirus E1A gene products. Mol. Cell. Biol. 11:2116-2124.
85. Yaciuk, P., and E. Moran. 1991. Analysis with specific polyclonal antiserum indicates that the E1A-associated 300-kDa product is a stable nuclear phosphoprotein that undergoes cell cycle phase-specific modification. Mol. Cell. Biol. 11:5389-5397.
86. Yee, S.-P., and P. E. Branton. 1985. Detection of cellular proteins associated with human adenovirus type 5 early region 1A polypeptides. Virology 147:142-153.
87. Yew, P. R., and A. J. Berk. 1992. Inhibition of p53 transactivation required for transformation by adenovirus early IB protein. Nature (London) 357:82-85.
88. Yew, P. R., X. Liu, and A. J. Berk. 1994. Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53. Genes Dev. 8:190-202.
89. Zamanian, M., and N. B. LaThangue. 1992. Adenovirus E1a prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor. EMBO J. 11:2603-2610.
90. Zantema, A., J. A. M. Fransen, A. Davis-Olivier, F. C. S. Ramaekers, G. P. Vooijs, B. DeLeys, and A. J. van der Eb. 1985a. Localization of the E1B proteins of adenovirus 5 in transformed cells, as revealed by interaction with monoclonal antibodies. Virology 142:44-58.
91. Zantema, A., P. I. Schrier, A. Davis-Olivier, T. van Laar, R. T. M. J. Vaessen, and A. J. van der Eb. 1985b. Adenovirus serotype determines association and localization of the large ElB tumor antigen with cellular tumor antigen p53 in transformed cells. Mol. Cell. Biol. 5:3084-3091.
92. Zerler, B., R. J. Roberts, M. B. Matthews, and E. Moran. 1987. Different functional domains of the adenovirus E1A gene are involved in regulation of host cell cycle products. Mol. Cell. Biol. 7:821-829.
93. Zhu, J. Y., M. Abate, P. W. Rice, and C. N. Cole. 1991. The ability of simian virus 40 large T antigen to immortalize primary mouse embryo fibroblasts cosegregates with its ability to bind to p53. J. Virol. 65:6872-6880.