Regio- and stereoselectivity in the metabolism of benzo[c]phenanthrene mediated by genetically engineered V79 Chinese hamster cells expressing rat and human cytochromes P450

Environmental Toxicology and Pharmacology

Volumn 5, Issue 3, 1998, Pages 179-196

  Seidel, Albrecht ^a   Soballa, Volker J ^b   Raab, Gottfried ^c   Frank, Heinz ^a   Greim, Helmut ^b,d   Grimmer, Gernot ^c   Jacob, Jürgen ^c   Doehmer, Johannes ^b  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c Biochemisches Inst U   (Germany)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Benzo c phenanthrene; Cytochrome P450; Dihydrodiol epoxides; Fjord region; Metabolism; Polycyclic aromatic hydrocarbons; Toxicity; V79 Chinese hamster cells

Indexed keywords

BENZO[C]PHENANTHRENE; CYTOCHROME P450; EPOXIDE; PHENANTHRENE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHINESE HAMSTER; CONCENTRATION RESPONSE; CYTOTOXICITY; ENANTIOMER; ENZYME ACTIVITY; GENETIC ENGINEERING; HYDROLYSIS; METABOLISM; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY;

EID: 0031861991     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1382-6689(97)10073-4     Document Type: Article

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