Benzo[c]phenanthrene is activated to DNA-binding diol epoxides in the human mammary carcinoma cell line MCF-7 but only limited activation occurs in mouse skin

Carcinogenesis

Volumn 17, Issue 10, 1996, Pages 2237-2244

  Einolf, Heidi J ^a   Amin, Shantu ^b   Yagi, Haruhiko ^c   Jerina, Donald M ^c   Baird, William M ^a  

^a PURDUE UNIVERSITY   (United States)

^b AMERICAN HEALTH FOUNDATION   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; DEOXYADENOSINE DERIVATIVE; DEOXYGUANOSINE; EPOXIDE; PHENANTHRENE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOMA; CELL STRAIN MCF 7; CIS TRANS ISOMERISM; CONTROLLED STUDY; DNA ADDUCT; DNA BINDING; FEMALE; HUMAN; HUMAN CELL; METABOLIC ACTIVATION; METABOLITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SKIN CARCINOGENESIS;

ANIMALS; BIOTRANSFORMATION; BREAST NEOPLASMS; CARCINOGENICITY TESTS; CARCINOMA; DNA ADDUCTS; DNA, NEOPLASM; EPOXY COMPOUNDS; FEMALE; HUMANS; MICE; PHENANTHRENES; SKIN; SPECIES SPECIFICITY; TUMOR CELLS, CULTURED;

EID: 0029824917     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.10.2237     Document Type: Article

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