Stable expression of human cytochrome P450 3A4 in conjunction with human NADPH-cytochrome P450 oxidoreductase in V79 Chinese hamster cells

Archives of Biochemistry and Biophysics

Volumn 332, Issue 2, 1996, Pages 295-304

  Schneider, Anneliese ^a   Schmalix, Wolfgang A ^a   Siruguri, Vasanthi ^b   De Groene, Els M ^c   Horbach, G Jean ^c   Kleingeist, Britta ^d   Lang, Dieter ^d   Böcker, Ronald ^d   Belloc, Claire ^e   Beaune, Philippe ^e   Greim, Helmut ^a,f   Doehmer, Johannes ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b NATIONAL INSTITUTE OF NUTRITION   (India)

^c UTRECHT UNIVERSITY   (Netherlands)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^e Section of Radiology   (France)

^f INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

cytochrome P450 3A4; metabolism; midazolam; NADPH cytochrome P450 reductase; nifedipine; testosterone; V79 Chinese hamster cells

Indexed keywords

AFLATOXIN B1; CYTOCHROME P450; MIDAZOLAM; NIFEDIPINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; TESTOSTERONE;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CHINESE HAMSTER; ENZYME ACTIVITY; ENZYME SYNTHESIS; GENE EXPRESSION; GENETIC ENGINEERING; GENOTOXICITY; HYDROXYLATION; METABOLIC ACTIVATION; NONHUMAN; PRIORITY JOURNAL; XENOBIOTIC METABOLISM;

EID: 0030586725     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1996.0345     Document Type: Article

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