-
1
-
-
0032032797
-
Eukaryotic DNA topoisomerase IIβ
-
Austin CA and Marsh KL (1998) Eukaryotic DNA topoisomerase IIβ. Bioessays 20:215-226.
-
(1998)
Bioessays
, vol.20
, pp. 215-226
-
-
Austin, C.A.1
Marsh, K.L.2
-
2
-
-
0028826231
-
Potentiation of temozolamide-induced cytotoxicity: A comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors
-
Boulton S, Pemberton LC, Porteous JK, Curtin NJ, Griffin RJ, Golding BT, and Durcacz BW (1995) Potentiation of temozolamide-induced cytotoxicity: A comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors. Br J Cancer 72:849-856.
-
(1995)
Br J Cancer
, vol.72
, pp. 849-856
-
-
Boulton, S.1
Pemberton, L.C.2
Porteous, J.K.3
Curtin, N.J.4
Griffin, R.J.5
Golding, B.T.6
Durcacz, B.W.7
-
3
-
-
0028954441
-
Relationship of DNA topoisomerase IIα and β expression to cytotoxicity of antineoplastic agents in human acute lymphoblastic leukemia cell lines
-
Brown GA, McPherson JP, Gu L, Hedley DW, Toso R, Deuchars KL, Freedman MH, and Goldenberg GJ (1995) Relationship of DNA topoisomerase IIα and β expression to cytotoxicity of antineoplastic agents in human acute lymphoblastic leukemia cell lines. Cancer Res 55:78-82.
-
(1995)
Cancer Res
, vol.55
, pp. 78-82
-
-
Brown, G.A.1
McPherson, J.P.2
Gu, L.3
Hedley, D.W.4
Toso, R.5
Deuchars, K.L.6
Freedman, M.H.7
Goldenberg, G.J.8
-
4
-
-
0029802613
-
Topoisomerase II-etoposide interactions direct the formation of drug-induced enzyme-DNA cleavage complexes
-
Burden AD, Kingma PS, Froelich-Ammon SJ, Bjornsti M, Patchan MW, Thompson RB, and Osheroff N (1996) Topoisomerase II-etoposide interactions direct the formation of drug-induced enzyme-DNA cleavage complexes. J Biol Chem 271:29238-29244.
-
(1996)
J Biol Chem
, vol.271
, pp. 29238-29244
-
-
Burden, A.D.1
Kingma, P.S.2
Froelich-Ammon, S.J.3
Bjornsti, M.4
Patchan, M.W.5
Thompson, R.B.6
Osheroff, N.7
-
5
-
-
0025147256
-
DNA double-strand break repair pathways and cellular tolerance to inhibitors of topoisomerase II
-
Caldecott K, Banks G, and Jeggo P (1990) DNA double-strand break repair pathways and cellular tolerance to inhibitors of topoisomerase II. Cancer Res 50:5778-5783.
-
(1990)
Cancer Res
, vol.50
, pp. 5778-5783
-
-
Caldecott, K.1
Banks, G.2
Jeggo, P.3
-
6
-
-
0027397044
-
The induction and reversal of topoisomerase II cleavable complexes formed by nuclear extract from the CHO DNA repair mutant, xrs1
-
Caldecott K, Banks G, and Jeggo P (1993) The induction and reversal of topoisomerase II cleavable complexes formed by nuclear extract from the CHO DNA repair mutant, xrs1. Mutat Res 293:259-267.
-
(1993)
Mutat Res
, vol.293
, pp. 259-267
-
-
Caldecott, K.1
Banks, G.2
Jeggo, P.3
-
7
-
-
0029842497
-
Method for quantifying expression of functionally active topoisomerase II in patients with leukaemia
-
Cattan AR, Levett D, Douglas EA, Middleton PG, and Taylor PRA (1996) Method for quantifying expression of functionally active topoisomerase II in patients with leukaemia. J Clin Pathol 49:848-852.
-
(1996)
J Clin Pathol
, vol.49
, pp. 848-852
-
-
Cattan, A.R.1
Levett, D.2
Douglas, E.A.3
Middleton, P.G.4
Taylor, P.R.A.5
-
8
-
-
0023891441
-
Reduced DNA topoisomerase II activity and drug-stimulated DNA cleavage in 9-hydroxyellipticine resistant cells
-
Charcosset J, Saucier J, and Jacquemin-Sablon A (1988) Reduced DNA topoisomerase II activity and drug-stimulated DNA cleavage in 9-hydroxyellipticine resistant cells. Biochem Pharmacol 37:2145-2149.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 2145-2149
-
-
Charcosset, J.1
Saucier, J.2
Jacquemin-Sablon, A.3
-
9
-
-
0025317440
-
Mechanism of epipodophyllotoxin- Induced cell death in poly(adenosine-diphosphate-ribose) synthesisdeficient V79 Chinese hamster cell lines
-
Chaterjee S, Trivedi D, Petzold J, and Berger NA (1990) Mechanism of epipodophyllotoxin-induced cell death in poly(adenosine-diphosphate-ribose) synthesisdeficient V79 Chinese hamster cell lines. Cancer Res 50:2713-2718.
-
(1990)
Cancer Res
, vol.50
, pp. 2713-2718
-
-
Chaterjee, S.1
Trivedi, D.2
Petzold, J.3
Berger, N.A.4
-
10
-
-
0029844281
-
Etoposide causes illegitimate V (D) J recombination in human lymphoblastoid leukemic cells
-
Chen C, Fuscoe JC, Liu Q, and Relling MV (1996) Etoposide causes illegitimate V (D) J recombination in human lymphoblastoid leukemic cells. Blood 88:2210-2218.
-
(1996)
Blood
, vol.88
, pp. 2210-2218
-
-
Chen, C.1
Fuscoe, J.C.2
Liu, Q.3
Relling, M.V.4
-
11
-
-
0029929672
-
Hypersensitivity of human testicular tumors to etoposide-induced apoptosis is associated with functional p53 and a high Bax:Bcl-2 ratio
-
Chresta CM, Masters JRW, and Hickman JA (1996) Hypersensitivity of human testicular tumors to etoposide-induced apoptosis is associated with functional p53 and a high Bax:Bcl-2 ratio. Cancer Res 56:1834-1841.
-
(1996)
Cancer Res
, vol.56
, pp. 1834-1841
-
-
Chresta, C.M.1
Masters, J.R.W.2
Hickman, J.A.3
-
12
-
-
0030448769
-
Drug sensitivity and sequence specificity of human recombinant DNA topoisomerases IIα (p170) and IIβ (p180)
-
Cornarotti M, Tinelli S, Willmore E, Zunino F, Fisher LM, Austin CA, and Capranico G (1996) Drug sensitivity and sequence specificity of human recombinant DNA topoisomerases IIα (p170) and IIβ (p180). Mol Pharmacol 50:1463-1471.
-
(1996)
Mol Pharmacol
, vol.50
, pp. 1463-1471
-
-
Cornarotti, M.1
Tinelli, S.2
Willmore, E.3
Zunino, F.4
Fisher, L.M.5
Austin, C.A.6
Capranico, G.7
-
13
-
-
0024204667
-
Altered catalytic activity of and DNA cleavage by DNA topoisomerase II from human leukemic cells selected for resistance to VM-26
-
Danks MK, Schmidt CA, Cirtain MC, Suttle DP, and Beck WT (1988) Altered catalytic activity of and DNA cleavage by DNA topoisomerase II from human leukemic cells selected for resistance to VM-26. Biochemistry 27:8861-8869.
-
(1988)
Biochemistry
, vol.27
, pp. 8861-8869
-
-
Danks, M.K.1
Schmidt, C.A.2
Cirtain, M.C.3
Suttle, D.P.4
Beck, W.T.5
-
14
-
-
0028973467
-
Cloning and characterisation of full-length cDNAs coding for the DNA topoisomerase IIβ from Chinese hamster lung cells sensitive and resistant to 9-OH-ellipticine
-
Dereuddre S, Frey S, Delaporte C, and Jacquemin-Sablon A (1995) Cloning and characterisation of full-length cDNAs coding for the DNA topoisomerase IIβ from Chinese hamster lung cells sensitive and resistant to 9-OH-ellipticine. Biochim Biophys Acta 1264:178-182.
-
(1995)
Biochim Biophys Acta
, vol.1264
, pp. 178-182
-
-
Dereuddre, S.1
Frey, S.2
Delaporte, C.3
Jacquemin-Sablon, A.4
-
15
-
-
0024432691
-
Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II
-
Drake FH, Hofmann GA, Bartus HF, Mattern MA, Crooke ST, and Mirabelli CK (1989) Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II. Biochemistry 28:8154-8160.
-
(1989)
Biochemistry
, vol.28
, pp. 8154-8160
-
-
Drake, F.H.1
Hofmann, G.A.2
Bartus, H.F.3
Mattern, M.A.4
Crooke, S.T.5
Mirabelli, C.K.6
-
16
-
-
0029744782
-
Detection and quantification of melphalan-DNA adducts at the single cell level in hematopoietic tumor cells
-
Frank AJ, Proctor SJ, and Tilby MJ (1996) Detection and quantification of melphalan-DNA adducts at the single cell level in hematopoietic tumor cells. Blood 88:977-984.
-
(1996)
Blood
, vol.88
, pp. 977-984
-
-
Frank, A.J.1
Proctor, S.J.2
Tilby, M.J.3
-
17
-
-
0029563719
-
Stratford IJ, Harris AL, and Hickson ID. Relationship between expression of topoisomerase II isoforms and intrinsic sensitivity to topoisomerase II inhibitors in breast cancer cell lines
-
Houlbrook S, Addison CM, Davies SL, Carmichael J (1995) Stratford IJ, Harris AL, and Hickson ID. Relationship between expression of topoisomerase II isoforms and intrinsic sensitivity to topoisomerase II inhibitors in breast cancer cell lines. Br J Cancer 72:1454-1461.
-
(1995)
Br J Cancer
, vol.72
, pp. 1454-1461
-
-
Houlbrook, S.1
Addison, C.M.2
Davies, S.L.3
Carmichael, J.4
-
18
-
-
0024353277
-
Evidence for the reversibility of cellular DNA lesion induced by mammalian topoisomerase II poisons
-
Hsiang Y and Liu LF (1989) Evidence for the reversibility of cellular DNA lesion induced by mammalian topoisomerase II poisons. J Biol Chem 264:9713-9715.
-
(1989)
J Biol Chem
, vol.264
, pp. 9713-9715
-
-
Hsiang, Y.1
Liu, L.F.2
-
19
-
-
0029780802
-
The clinical pharmacology of etoposide: An update
-
Joel S (1996) The clinical pharmacology of etoposide: An update. Cancer Treat Rev 22:179-221.
-
(1996)
Cancer Treat Rev
, vol.22
, pp. 179-221
-
-
Joel, S.1
-
20
-
-
0020615725
-
Effects of the epipodophyllotoxin VP-16-213 on cell cycle traverse, DNA synthesis, and DNA strand size in cultures of human leukemic lymphoblasts
-
Kalwinsky DK, Look AT, Ducore J, and Fridlans A. (1983) Effects of the epipodophyllotoxin VP-16-213 on cell cycle traverse, DNA synthesis, and DNA strand size in cultures of human leukemic lymphoblasts. Cancer Res 43:1592-1597.
-
(1983)
Cancer Res
, vol.43
, pp. 1592-1597
-
-
Kalwinsky, D.K.1
Look, A.T.2
Ducore, J.3
Fridlans, A.4
-
21
-
-
0027892521
-
bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair
-
Kamesaki S, Kamesaki H, Jorgenson TJ, Tanizawa A, Pommier Y, and Cossman J (1993) bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair. Cancer Res 53:4251-4256.
-
(1993)
Cancer Res
, vol.53
, pp. 4251-4256
-
-
Kamesaki, S.1
Kamesaki, H.2
Jorgenson, T.J.3
Tanizawa, A.4
Pommier, Y.5
Cossman, J.6
-
22
-
-
0025817295
-
Inhibition of replicon initiation in human cells following stabilisation of topoisomerase-DNA cleavable complexes
-
Kaufmann WK, Boyer JC, Estabrooks LL, and Wilson SJ (1991) Inhibition of replicon initiation in human cells following stabilisation of topoisomerase-DNA cleavable complexes. Mol Cell Biol. 11:3711-3718.
-
(1991)
Mol Cell Biol.
, vol.11
, pp. 3711-3718
-
-
Kaufmann, W.K.1
Boyer, J.C.2
Estabrooks, L.L.3
Wilson, S.J.4
-
23
-
-
0018882091
-
Type II DNA topoisomerases: Enzymes that can unknot a topologically knotted DNA molecule via a reversible double strand break
-
Liu LF, Liu CC, and Alberts BM (1980) Type II DNA topoisomerases: enzymes that can unknot a topologically knotted DNA molecule via a reversible double strand break. Cell 19:697-707.
-
(1980)
Cell
, vol.19
, pp. 697-707
-
-
Liu, L.F.1
Liu, C.C.2
Alberts, B.M.3
-
24
-
-
0021864097
-
Single- and double-strand DNA breakage and repair in human lung adenocarcinoma cells exposed to etoposide and teniposide
-
Long BH, Musiai ST, and Brattain MG (1985) Single- and double-strand DNA breakage and repair in human lung adenocarcinoma cells exposed to etoposide and teniposide. Cancer Res 45:3106-3112.
-
(1985)
Cancer Res
, vol.45
, pp. 3106-3112
-
-
Long, B.H.1
Musiai, S.T.2
Brattain, M.G.3
-
25
-
-
0025997529
-
Mechanisms of resistance to etoposide and teniposide in acquired resistant human colon and lung carcinoma cell lines
-
Long BH, Wang L, Lorico A, Wang RCC, Brattain MG, and Casazza A (1991) Mechanisms of resistance to etoposide and teniposide in acquired resistant human colon and lung carcinoma cell lines. Cancer Res 51:5275-5284.
-
(1991)
Cancer Res
, vol.51
, pp. 5275-5284
-
-
Long, B.H.1
Wang, L.2
Lorico, A.3
Wang, R.C.C.4
Brattain, M.G.5
Casazza, A.6
-
26
-
-
0029028957
-
Increased rate of adenosine triphosphate-dependent etoposide (VP-16) efflux in a murine leukemia cell line overexpressing the multidrug resistance-associated protein (MRP) gene
-
Lorico A, Rappa G, Srimatkcandada S, Catapano CV, Fernandes DJ, Germino JF, and Sartorelli AC (1995) Increased rate of adenosine triphosphate-dependent etoposide (VP-16) efflux in a murine leukemia cell line overexpressing the multidrug resistance-associated protein (MRP) gene. Cancer Res 55:4352-4360.
-
(1995)
Cancer Res
, vol.55
, pp. 4352-4360
-
-
Lorico, A.1
Rappa, G.2
Srimatkcandada, S.3
Catapano, C.V.4
Fernandes, D.J.5
Germino, J.F.6
Sartorelli, A.C.7
-
27
-
-
0030582837
-
Capranico G, Fisher LM, and Austin CA. Amsacrine-promoted DNA cleavage site determinants for the two human DNA topoisomerase II isoforms α and β
-
Marsh KL, Willmore E, Tinelli S, Cornarotti M, Meczes E (1996) Capranico G, Fisher LM, and Austin CA. Amsacrine-promoted DNA cleavage site determinants for the two human DNA topoisomerase II isoforms α and β. Biochem Pharmacol 52:1675-1685.
-
(1996)
Biochem Pharmacol
, vol.52
, pp. 1675-1685
-
-
Marsh, K.L.1
Willmore, E.2
Tinelli, S.3
Cornarotti, M.4
Meczes, E.5
-
28
-
-
0031014248
-
Complementation of temperature-sensitive topoisomerase II mutations in Saccharomyces cerevisiae by a human TOP2β construct allows the study of topoisomerase IIβ inhibitors in yeast
-
Meczes EL, Marsh KL, Fisher LM, Rogers MP, and Austin CA (1997) Complementation of temperature-sensitive topoisomerase II mutations in Saccharomyces cerevisiae by a human TOP2β construct allows the study of topoisomerase IIβ inhibitors in yeast. Cancer Chemother Pharmacol 39:367-375.
-
(1997)
Cancer Chemother Pharmacol
, vol.39
, pp. 367-375
-
-
Meczes, E.L.1
Marsh, K.L.2
Fisher, L.M.3
Rogers, M.P.4
Austin, C.A.5
-
29
-
-
0027443694
-
Altered topoisomerase IIα in a drug-resistant small cell lung cancer cell line selected in VP-16
-
Mirski SEL, Evans CD, Almquist KC, Slovak ML, and Cole S (1993) Altered topoisomerase IIα in a drug-resistant small cell lung cancer cell line selected in VP-16. Cancer Res 53:4866-4873.
-
(1993)
Cancer Res
, vol.53
, pp. 4866-4873
-
-
Mirski, S.E.L.1
Evans, C.D.2
Almquist, K.C.3
Slovak, M.L.4
Cole, S.5
-
30
-
-
0024395605
-
Effect of antineoplastic agents on the DNA cleavage/religation reaction of eukaryotic topoisomerase II: Inhibition of religation by etoposide
-
Osheroff N (1989) Effect of antineoplastic agents on the DNA cleavage/religation reaction of eukaryotic topoisomerase II: Inhibition of religation by etoposide. Biochemistry 28:6157-6160.
-
(1989)
Biochemistry
, vol.28
, pp. 6157-6160
-
-
Osheroff, N.1
-
31
-
-
0027400805
-
Novel selection and genetic characterisation of an etoposide-resistant human leukaemic CCRF-CEM cell line
-
Patel S, and Fisher LM (1993) Novel selection and genetic characterisation of an etoposide-resistant human leukaemic CCRF-CEM cell line. Br J Cancer 67:456-463.
-
(1993)
Br J Cancer
, vol.67
, pp. 456-463
-
-
Patel, S.1
Fisher, L.M.2
-
32
-
-
0028033906
-
Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors
-
Pommier Y, Leteurtre F, Fesen MR, Fujimori A, Bertrand R, Solary E, Kohlhagen G, and Kohn KW (1994) Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors. Cancer Invest 12:530-542.
-
(1994)
Cancer Invest
, vol.12
, pp. 530-542
-
-
Pommier, Y.1
Leteurtre, F.2
Fesen, M.R.3
Fujimori, A.4
Bertrand, R.5
Solary, E.6
Kohlhagen, G.7
Kohn, K.W.8
-
33
-
-
0030445449
-
Formation of topoisomerase IIα complexes with nascent DNA is related to VM-26 induced cytotoxicity
-
Qiu J, Catapano V, Fernandes DJ (1996) Formation of topoisomerase IIα complexes with nascent DNA is related to VM-26 induced cytotoxicity. Biochemistry 35:16354-16360.
-
(1996)
Biochemistry
, vol.35
, pp. 16354-16360
-
-
Qiu, J.1
Catapano, V.2
Fernandes, D.J.3
-
34
-
-
0028325365
-
Altered stability of etoposide-induced topoisomerase II-DNA complexes in resistant human leukaemia K562 cells
-
Ritke MK, Roberts D, Allan JR, Bergoltz VV, and Yalowich JC (1994) Altered stability of etoposide-induced topoisomerase II-DNA complexes in resistant human leukaemia K562 cells. Br J Cancer 69:687-697.
-
(1994)
Br J Cancer
, vol.69
, pp. 687-697
-
-
Ritke, M.K.1
Roberts, D.2
Allan, J.R.3
Bergoltz, V.V.4
Yalowich, J.C.5
-
35
-
-
0025758625
-
Effects of antineoplastic drugs on the poststrand passage DNA cleavage/religation equilibrium of topoisomerase II
-
Robinson MJ and Osheroff N (1991) Effects of antineoplastic drugs on the poststrand passage DNA cleavage/religation equilibrium of topoisomerase II, Biochemistry 30:1807-1813.
-
(1991)
Biochemistry
, vol.30
, pp. 1807-1813
-
-
Robinson, M.J.1
Osheroff, N.2
-
36
-
-
0030007125
-
Mapping of DNA topoisomerase II poisons (etoposide, Clerocidin) and catalytic inhibitors (aclarubicin, ICRF-187) to four distinct steps in the topoisomerase II catalytic cycle
-
Sehested M and Jensen PB (1996) Mapping of DNA topoisomerase II poisons (etoposide, Clerocidin) and catalytic inhibitors (aclarubicin, ICRF-187) to four distinct steps in the topoisomerase II catalytic cycle. Biochem Pharmacol 51:879-886.
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 879-886
-
-
Sehested, M.1
Jensen, P.B.2
-
37
-
-
0031029576
-
2 to M transition: Implications for gene therapy
-
2 to M transition: implications for gene therapy. Cancer Res 57:818-823.
-
(1997)
Cancer Res
, vol.57
, pp. 818-823
-
-
Skladanowski, A.1
Larsen, A.K.2
-
38
-
-
0031018456
-
Topoisomerase II inhibitors fail to induce chromosome-type aberrations in etoposide-resistant cells: Evidence for essential contribution of the cleavable complex formation to the induction of chromosome-type aberrations
-
Suzuki H, Tarumoto Y, and Ohsawa M (1997) Topoisomerase II inhibitors fail to induce chromosome-type aberrations in etoposide-resistant cells: evidence for essential contribution of the cleavable complex formation to the induction of chromosome-type aberrations. Mutagenesis 12:29-33.
-
(1997)
Mutagenesis
, vol.12
, pp. 29-33
-
-
Suzuki, H.1
Tarumoto, Y.2
Ohsawa, M.3
-
39
-
-
84961983931
-
Intrinsic conformational preferences of the Hoechst dye family and their influence on DNA binding
-
Vega MC, Coll M, and Aleman C (1996) Intrinsic conformational preferences of the Hoechst dye family and their influence on DNA binding. Eur J. Biochem 239:376-383.
-
(1996)
Eur J. Biochem
, vol.239
, pp. 376-383
-
-
Vega, M.C.1
Coll, M.2
Aleman, C.3
-
40
-
-
0030014783
-
DNA Topoisomerases
-
Wang JC (1996) DNA Topoisomerases. Ann Rev Biochem 65:635-692.
-
(1996)
Ann Rev Biochem
, vol.65
, pp. 635-692
-
-
Wang, J.C.1
|