Flow cytometric identification of candidate normal stem cell populations in CD45-negative B-cell precursor acute lymphoblastic leukaemia

British Journal of Haematology

Volumn 100, Issue 3, 1998, Pages 501-508

  Vormoor, J ^a   Baersch, G ^a   Baumann, M ^a   Ritter, J ^a   Jurgens H ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

B cell precursor ALL; CD34; Stem cells

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; B LYMPHOCYTE ACTIVATION; BLAST TRANSFORMATION; BONE MARROW PURGING; CELL COMPARTMENTALIZATION; CELL POPULATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKEMIA CELL; MINIMAL RESIDUAL DISEASE; PRIORITY JOURNAL; PROGNOSIS; SIGNAL TRANSDUCTION; STEM CELL;

ACUTE DISEASE; ANTIGENS, CD19; ANTIGENS, CD34; ANTIGENS, CD45; BONE MARROW CELLS; FLOW CYTOMETRY; HUMANS; LEUKEMIA, PRE-B-CELL; STEM CELLS;

EID: 0031840553     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.00610.x     Document Type: Article

References (37)

1. Baersch, G., Baumann, M., Meltzer, J., Möllers, T., Ritter, J., Jürgens, H. & Vormoor, J. (1996) Durchflusszytometrische Charakterisierung von Reifungsvorgängen und stammzellnahen Zellpopulationen bei der B-Vorläuferzell-ALL im Kindesalter. Klinische Pädiatrie, 208, 160-167.
2. Baersch, G., Möllers, T., Hötte, A., Dockhorn-Dworniczak, B., Rübe, C., Ritter, J., Jürgens, H. & Vormoor, J. (1997) Good engraftment of B-cell precursor ALL in NOH-SCID mice. Klinische Pädiatrie, 209, 178-185.
3. Baum, C.M., Weissman, I.L., Tsukamoto, A.S., Buckle, A.-M. & Peault, B. (1992) Isolation of a candidate human hematopoietic stem-cell population. Proceedings of the National Academy of Sciences of the United States of America, 89, 2804-2808.
4. Behm, F.G., Raimondi, S.C., Schell, M.J., Look, A.T., Rivera, G.K. & Pui, C-H. (1992) Lack of CD45 antigen on blast cells in childhood acute lymphoblastic leukemia is associated with chromosomal hyperdiploidy and other favorable prognostic features. Blood, 79, 1011-1016.
5. Billet, A.L., Kornmehl, E., Tarbell, N.J., Weinstein, H.J., Gelber, R.D., Ritz, J. & Sallan, S.E. (1993) Autologous bone marrow transplantation after a long first remission for children with recurrent acute lymphoblastic leukemia. Blood, 81, 1651-1657.
6. Bonnet, D. & Dick, J.E. (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive haemopoietic cell. Nature Medicine, 3, 730-737.
7. Borkhardt, A., Cazzaniga, G., Viehmann, S., Valsecchi, M.G., Ludwig, W.D., Burci, L., Mangioni, S., Schrappe, M., Riehm, H., Lampert, F., Basso, G., Masera, G., Harbott, J. & Biondi, A. (1997) Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials. Blood, 90, 571-577.
8. Borowitz, M.J., Guenther, K.L., Shults, K.E. & Stelzer, G.T. (1993) Immunophenotyping of acute leukemia by flow cytometric analysis. American Journal of Clinical Pathology, 100, 534-540.
9. Borowitz, M.J., Shuster, J., Carroll, A.J., Nash, M., Look, A.T., Camitta, B., Mahoney, D., Lauer, S.J. & Pullen, D.J. (1997) Prognostic significance of fluorescence intensity of surface marker expression in childhood B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group study. Blood, 89, 3960-3966.
10. Brenner, M.K., Rill, D.R., Moen, R.C., Krance, R.A., Mirro, J., Anderson, W.F. & Ihle, J.N. (1993) Gene-marking to trace origin of relapse after autologous bone-marrow transplantation. Lancet, 341, 85-86.
11. Craig, W., Kay, R., Cutler, R.L. & Lansdorp, P.M. (1993) Expression of Thy-1 on human hematopoietic progenitor cells. Journal of Experimental Medicine, 177, 1331-1342.
12. Craig, W., Poppema, S., Little, M.-T., Dragowska, W. & Lansdorp, P.M. (1994) CD45 isoform expression on human haemopoietic cells at different stages of development. British Journal of Haematology, 88, 24-30.
13. + cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML. Blood, 83, 3068-3076.
14. + myeloid progenitors using CD45-RA analysis. Blood, 81, 2301-2309.
15. - progenitor cells in c-ALL carry the clone specific T-cell receptor delta gene rearrangement. Blood, 86, (Suppl. 1). 730a.
16. -7. Proceedings of the National Academy of Sciences of the United States of America, 92, 537-541.
17. Gross, H.J., Verwer, B., Houck, D. & Recktenwald, D. (1993) Detection of rare cells at a frequency of one per million by flow cytometry. Cytometry, 14, 519-526.
18. + subpopulations. Blood, 86, 2906-2912.
19. Knuutlla, S., Alitalo, R. & Ruutu, T. (1993) Power of the MAC (morphology antibody chromosomes) method in distinguishing reactive and clonal cells: a report of a patient with acute lymphatic leukemia, eosinophils and t(5;14). Genes, Chromosomes and Cancer, 8, 219-223.
20. Lamkin, T., Brooks, J., Annett, G., Roberts, W. & Weinberg, K. (1994) Immunophenotypic differences between putative hematopoietic stem cells and childhood B-cell precursor acute lymphoblastic leukemia cells. Leukemia, 8, 1871-1878.
21. Lapidot, T., Sirard, C., Vormoor, J., Murdoch, B., Hoang, T., Caceres-Cortes, J., Minden, M., Patterson, B., Caligiuri, M.A. & Dick, J.E. (1994) A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature, 367, 645-648.
22. Larochelle, A., Vormoor, J., Hahnenberg, H., Wang, J.C.Y., Bhatia, M., Lapidot, T., Moritz, T., Murdoch, B., Xiao, X.L., Kato, I., Williams, D.A. & Dick, J.E. (1996) Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mice using retroviral gene marking and cell purification: implications for gene therapy. Nature Medicine, 2, 1329-1337.
23. Larramendy, M.L., El-Rifai, W., Saarinen, U., Alitalo, R., Luomahaara, S. & Knuutila, S. (1995) Myeloid lineage involvement in acute lymphoblastic leukemia: a Morphology Antibody Chromosomes (MAC) study. Experimental Hematology, 23, 1562-1566.
24. Pontvert-Declucq, S., Breton-Gorius, J., Schmitt, C., Baillou, C., Guichard, J., Najman, A. & Lemoine, F.M. (1993) Characterization and functional analysis of adult human bone marrow cells subsets in relation to B-lymphoid development. Blood, 82, 417-429.
25. - marrow compartment in children with acute lymphoblastic leukemia. Leukemia, 11, 1508-1515.
26. Reiter, A., Schrappe, M., Ludwig, W.-D., Hiddemann, W., Sauter, S., Henze, G., Zimmermann, M., Lampert, F., Havers, W., Niethammer, D., Odenwald, E., Ritter, J., Mann, G., Welte, K., Gadner, H. & Riehm, H. (1994) Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients: results and conclusions of the multicenter trial ALL-BFM 86. Blood, 84, 3122-3133.
27. Rill, D.R., Santana, V.M., Roberts, W.M., Nilson, T., Bowman, L.C., Krance, R.A., Heslop, H.E., Moen, R.C., Ihle, J.N. & Brenner, M.K. (1994) Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells. Blood, 84, 380-583.
28. Shah, V.O., Civin, C.I. & Loken, M.R. (1988) Flow cytometric analysis of human bone marrow. IV. Differential quantitative expression of T-200 common leukocyte antigen during normal hemopoiesis. Journal of Immunology, 140, 1861-1867.
29. Shapiro, H.M. (1995) Practical Flow Cytometry. Wiley-Liss, New York.
30. Sirard, C., Lapidot, T., Vormoor, J., Cashman, J.D., Doedens, M. Murdoch, B., Jamal, N., Messner, H., Addey, L., Minden, M., Laraya, P., Keating, A., Eaves, A., Lansdorp, P.M., Eaves, C.J. & Dick, J.E. (1996) Normal and leukemic SCID-repopulating cells (SRC) coexist in the hone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis. Blood, 87, 1539-1548.
31. Syrjälä, M., Anttila, V.-J., Ruutu, T. & Jansson, S-E. (1994) Flow cytometric detection of residual disease in acute leukemia by assaying blasts co-expressing mycloid and lymphatic antigens. Leukemia, 8, 1564-1570.
32. - progenitor cells. Blood, 77, 1218-1227.
33. Terstappen, L.W.M.M., Safford, M., Unterhalt, M., Könemann, S., Zurlutter, K., Piechotka, K., Drescher, M., Aul, C., Büchner, T., Hiddemann, W. & Wörmann, B. (1992) Flow cytometric characterization of acute myeloid leukemia. IV. Comparison to the differentiation pathway of normal hematopoietic progenitor cells. Leukemia, 6, 993-1000.
34. Verfaille, C., Blakolmer, K. & McGlave, P. (1990) Purified primitive human hematopoietic progenitor cells with long-term in vitro repopulating capacity adhere selectively to irradiated bone marrow stroma. Journal of Experimental Medicine, 172, 509-520.
35. Vervoordeldonk, S.E., Merle, P.A., Behrendt, H., Steenbergen, E.J., van den Berg, H., van den Wering, E.R., von dem Borne, A.E.G.K., van der Schoot, C.E., van Leeuwen, E.F. & Slaper-Cortenbach, I.C.M. (1997) PCR-positivity in harvested bone marrow predicts relapse after transplantation with autologous purged bone marrow in children in second remission of precursor B-cell acute leukaemia. British Journal of Haematology, 96, 395-402.
36. Vormoor, J., Lapidot, T., Pflumio, R. Risdon, G., Patterson, B., Broxmeyer, H.E. & Dick, J.E. (1994) Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice. Blood, 83, 2489-2497.
37. Vormoor, J., Ritter, J., Jürgens, H. & Dick, J.E. (1995) Significance of the SCID mouse models for the study of normal and leukemic human hemopoiesis and gene therapy. Onkologie, 18, 434-438.