Cytogenetically aberrant cells are present in the CD34+CD33-38-19- marrow compartment in children with acute lymphoblastic leukemia

Leukemia

Volumn 11, Issue 9, 1997, Pages 1508-1515

  Quijano, C A ^a   Moore II, D ^b   Arthur, D ^c   Feusner, J ^d   Winter, S S ^e   Pallavicini, M G ^b,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d CHILDREN S HOSPITAL OAKLAND   (United States)

^e UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acute lymphoblastic leukemia; CD34; Fluorescence in situ hybridization

Indexed keywords

CD19 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; CD38 ANTIGEN; LEUKEMIA ANTIGEN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; BONE MARROW; CHILD; CHILDHOOD LEUKEMIA; CLINICAL ARTICLE; CYTOGENETICS; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENOTYPE; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL;

EID: 0030804381     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2400754     Document Type: Article

References (12)

1. Dow LW, Martin P, Moohr J, Greenberg M, Macdougall LC, Najfeld V, Fialkow PJ. Evidence for clonal development of childhood acute lymphoblastic leukemia. Blood 1985; 66: 902-907.
2. Knuutila S, Teerenhovi L, Larramendy ML, Elonen E, Franssila KO, Nylund SJ, Timonen T, Heinonen K, Mahlamaki E, Winqvist R, et al. Cell lineage involvement of recurrent chromosomal abnormalities in hematologic neoplasms. Genes Chromosom Cancer 1994; 10: 95-102.
3. McCulloch EA. Stem cells in normal and leukemic hemopoieisis. Blood 1983, 62: 1-13.
4. Greaves MF. Differentiation-linked leukemogenesis in lymphocytes. Science 1986; 234: 697-704.
5. Tachibana N, Raimondi SC, Lauer SJ, Sartain P, Dow LW. Evi-dence for a multipotential stem cell disease in some childhood Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood 1987; 70: 1458-1461.
6. Greaves MF. Stem cell origins of leukaemia and curability. Br J Cancer 1993; 67: 413-423.
7. Szilvassy SJ, Cory S. Phenotypic and functional characterization of competitive long-term repopulating hematopoietic stem cells enriched from 5-fluorouracil-treated murine marrow. Blood 1993; 81: 2310-2320.
8. Stewart FM, Temeles D, Lowry P, Thraves T, Gross WW, Quesenberry PJ. Post-5-fluorouracil human marrow: stem cell characteristics and renewal properties after autologous marrow transplantation. Blood 1993; 81: 2283-2289.
9. Uckun FM, Jaszcz W, Chandan-Langlie M, Waddick KG, Gajl-Peczalska K, Song CW. Intrinsic radiation resistance of primary clonogenic blasts from children with newly diagnosed B-cell precursor acute lymphoblastic leukemia. J Clin Invest 1993; 91: 1044-1051.
10. -) in acute myeloid leukemia. Blood 1995; 86: 1139-1147.
11. Haase D, Feuring-Buske M, Konemann S, Fonatsch C, Troff C, Verbeek W, Pekrun A, Hiddemann W, Wormann B. Evidence for malignant transformation in acute myeloid leukemia at the level of early hematopoietic stem cells by cytogenetic analysis of CD34+ subpopulations. Blood 1995; 86: 2906-2912.
12. Civin CI, Strauss LC, Brovall C, Fackler MJ, Schwartz JF, Shaper JH. Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells. J Immunol 1984; 133: 157-165.